Chaur-Dong Hsu, MD, MPH, FACOG
Bingyun Bing Li, PhD
Associate Professor & Director
  • Department of Orthopaedics
    School of Medicine, West Virginia University,
    Morgantown, West Virginia,USA
    Phone:     681-285-596 (C), 304-293-1075 (O)
    Email:     bili@hsc.wvu.edu

Education

Institution and location

Field of study

Degree

Year(s)

Central South University, China

Materials Science & Engineering

BS

1990-1994

Chinese Academy of Sciences

Biomaterials Science & Engineering

MS

1994-1997

Chinese Academy of Sciences

Biomaterials

PhD

1997-2000

University of Notre Dame, USA

Advanced Orthopaedics Materials

Postdoc.

2000-2002

Louisiana Tech University, USA

Nanotechnology & Protein Eng.

Postdoc.

2002-2005

 

Biography

Dr. Bingyun Li received his PhD from the Chinese Academy of Sciences in 2000.  Currently, he is an Associate Professor with tenure at West Virginia University Medical School. Dr. Li is an active reviewer for more than 50 international journals. He is a member of the Society for Biomaterials (SFB), Orthopaedic Research Society (ORS), American Society for Microbiology (ASM), Materials Research Society (MRS), and American Chemical Society (ACS). Dr. Li’s research focuses on infection, immunology, nanomaterials, and drug delivery. He has authored more than 70 peer-reviewed research articles and book chapters. Dr. Li has received several prestigious awards including the Berton Rahn Prize from AO Foundation in 2011, the Pfizer Best Scientific Paper Award from Asia Pacific Orthopaedic Association Annual Meeting in 2013, and the Collaborative Exchange Award from Orthopaedic Research Society in 2013.

Research Interest

  • Orthopaedic infection
  • Immunotherapy
  • Orthopaedic Biomaterials,
  • Nanomedicine,
  • Controlled/Targeted Drug Delivery,
  • Cellular Interaction,
  •  Biomimetic

 

Scientific Activities:

Honors

2016

Dr. Li was invited by the Chair of the Scientific Program to chair the “Anti-infective biomaterials and device related infections” session at the 10th World Biomaterials Congress (WBC2016), Montreal, Canada, May 18, 2016.

2016

Dr. Li received the international travel award from WVU, March 2016.

2016

On behalf of Dr. Xingbo Liu, lead of the Electrochemical Systems Research Center, Dr. Li was named, among six researchers (Cheryl Ball, digital publishing; Dan Carder, diesel emissions research; Sally Hodder, clinical and translational sciences; Bingyun Li, electrochemical systems research; Maura McLaughlin, neutron stars and NANOGrav; Sean McWilliams, LIGO and gravitational waves) as Outstanding Researchers at President E. Gordon Gee’s special State of the University address in celebrating the University's highest designation of Carnegie Classification of Institutions of Higher Education, March 1, 2016.

2015

The collaborative work with Xingbo Liu was picked as one of the Crowd Choice Awards for Audience Favorites in Pitch Session 3 at the 2015 Trans Tech Energy (TTE) Business Development Conference, Morgantown, WV, and November 2015. It was presented by Trina Wafle.

2015

Included in the 70th Platinum Anniversary Edition of Marquis Who's Who in America.

2015

Dr. Li was awarded a Travel Grant (600 $), West Virginia University, March 2015.

2015

Our paper titled “Advances in CO2 capture technology” received the “Applied Energy Highly Cited Award” with a certificate, March 2015. The award was selected by the Editor-in-Chief and the Publisher as one (represents only 1.75% of papers in the journal during 2012-2013) of the most highly-cited papers published in the Applied Energy journal in 2012-2013.

2013

Dr. Li was awarded the Collaborative Exchange Award from the Orthopaedic Research Society (ORS), October, 2013.

2013

Dr. Li was awarded the APOA (Asia Pacific Orthopaedic Association) Pfizer Best Scientific Paper Award at the combined 9th Asia Pacific Spine Society Congress, 9th APOA Paediatric Section Congress, and 5th APOA Infection Section Scientific Meeting, Kuching, Malaysia, August 2013. The title of the paper is “Intra-cellular Staphylococcus aureus alone causes infection: Direct in vivo evidence”. The paper was among three finalists.

2013

Dr. Li was an invited faculty presenter at the combined 9th Asia Pacific Spine Society Congress, 9th APOA Paediatric Section Congress, and 5th APOA Infection Section Scientific Meeting, Kuching, Malaysia, August 2013.

2013

Dr. Li was the Invited speaker at the 2013 Student Night of the American

   

Publications

  1. Yan J, Liu X, Li B*. (2016). Capacity fade analysis of sulfur cathodes in lithium sulfur batteries. Advanced Sciences (Accepted).
  2. Wang Q, Yan J, Yang J, Li B*. (2016). Nanomaterials promise better bone repair. Materials Today (IF=14.107) DOI: 10.1016/j.mattod.2015.12.003.
  3. Wang X, Akhmedov NG, Hopkinson D, Hoffman J, Duan Y, Egbebi A, Resnik K, B Li*. (2016). Phase change amino acid salt separates into CO2-rich and CO2-lean phases upon interacting with CO2. Appl Energy (IF=5.011) 161:41-7.
  4. Yan J, Li B, Liu X*. (2015). Nano-porous sulfur-polyaniline electrodes for lithium-sulfur batteries. Nano Energy (IF=10.325) 18:245-52.
  5. Yan J, Liu X, Qi H, Li W, Zhou Y, Yao M, Li B*. (2015). High-performance lithium-sulfur batteries with a cost-effective carbon paper electrode and high sulfur-loading. Chem Mater (IF=8.354). 27:6394-401.
  6. Huang H, Chen AY, Ye X, Li B, Rojanasakul Y, Rankin GO, Chen YC*. (2015). Myricetin inhibits proliferation of cisplatin-resistant cancer cells through a p53-dependent apoptotic pathway. Int J Oncol (IF=3.025) 47:1494-02. PMID: 26315556.
  7. Yan J, Liu X, Yao M, Wang X, Wafle T, Li B*. Long-life, high-efficiency lithium-sulfur battery from nano-assembled cathode. Chem Mater (IF=8.354) 27:5080-7.
  8. Wang X, Akhmedov NG, Duan Y, Li B*. (2015). NMR studies of CO2 absorption and desorption in aqueous sodium salt of alanine. Energy & Fuels (IF=2.790) 29:3780-4.
  9. Armstead  AL,  Minarchick  VC,  Porter  DW,  Nurkiewicz  TR,  Li  B*.     (2015). Acute inflammatory responses of nanoparticles in an intra-tracheal instillation rat model. Plos One (IF=3.534), 10(3):e0118778. PMC4349695.
  10. Wang X, Chen YC, Li B*. (2015). Aligning 3D nanofibrous networks from self-assembled phenylalanine nanofibers. RSC Advances (IF=3.708), 5:8022-7. PMC4303580.
  11. Liu LZ*, Ding M, Zheng JZ, Zhu Y, Fenderson BA, Li B, Yu JJ, Jiang BH. (2015). Tungsten carbide-cobalt nanoparticles induce reactive oxygen species, AKT, ERK, AP-1, NF-κB, VEGF, and angiogenesis. Biol Trace Elem Res (IF=1.608), DOI: 10.1007/s12011-015- 0331-6.
  12. Duan Y, Lekse J, Wang X, Li B, Alcántar-Vázquez B, Pfeiffer H, Halley JW. (2015).
  13. Electronic structural, phonon dynamic properties and CO2 capture capabilities of Na2- αMαZrO3 (M=Li, K, α=0.0, 0.5, 1.0, 1.5, 2.0): First-principles density functional theory investigations and experimental validations. Phys Rev Appl, 3:044013.
  14. Yan J, Liu X, Li B*. (2015). Nano-assembled Na2FePO4F/carbon nanotube multi-layered cathodes for Na-ion batteries. Electrochem Comm (IF=4.287), 56:46-50.
  15. Yan J, Liu X, X Wang, Li B*. (2015). Long-life, high-efficiency lithium/sulfur batteries from sulfurized carbon nanotube cathodes. J Mater Chem A (JMC's IF=6.101), 3:10127-33.
  16. Yan J, Liu X, Li B*. (2014). Recent progress in Li-rich layered oxides as cathode materials for Li-ion batteries. RSC Advances (IF=3.708), 4(108):63268-84.
  17. Hamza  T,  Li  B*.  (2014).  Differential  responses  of  osteoblasts  and  macrophages  upon
  18. Staphylococcus aureus infection. BMC Microbiology (IF=3.10), 14:207. PMC4116603.
  19. Armstead A.L, Arena C.B, Li B*. (2014). Exploring the potential role of tungsten carbide cobalt (WC-Co) nanoparticle internalization in observed toxicity toward lung epithelial cells in vitro. Toxicol Appl Pharmacol (IF=3.975), 278:1-8. PMC4062194.
  20. Duan Y*, Zhang K, Li X, King D, Li B, Zhao L, Xiao Y. (2014). Ab initio thermodynamic study of the CO2 capture properties of M2CO3(M=Na, K)- and CaCO3-promoted MgO sorbents towards forming double salts. Aerosol Air Qual Res (IF=2.827), 14(2) 470-9.
  21. Hamza T, Dietz M, Pham D, Clovis N, Danley S, Li B*. (2013). Intra-cellular Staphylococcus aureus alone causes infection in vivo. Eur Cells Mater (IF=4.558), 25:341- 50.
  22. Wang X, Ding B, Li B*. (2013). Biomimetic electrospun nanofibrous structures for tissue engineering. Materials Today (IF=10.850), 16(6):229-41. PMC4130655.
  23. Li H, Hamza T, Tidwell JE, Clovis N, Li B*. (2013). Unique antimicrobial effects of platelet-rich plasma and its efficacy as a prophylaxis to prevent implant-associated spinal infection. Adv Healthcare Mater (IF=4.880), 2:1277-84. PMC3774283.
  24. Noore J, Noore A, Li B*. (2013). Cationic antimicrobial peptide LL-37 is effective against both extra- and intra-cellular Staphylococcus aureus. Antimicrob Agents Chemother (IF=4.841) 57(3):1283-90. PMC3591932.
  25. Li H, Li B*. (2013). PRP as a new approach to prevent infection: Preparation and in vitro
  26. antimicrobial properties of PRP. J Vis Exp (JoVE) 74, e50351. PMC3653398.
  27. Luo H, Li B*, Li Z, Cutler SJ, Rankin GO, Chen Y*. (2013). Chaetoglobosin K inhibits tumor angiogenesis through down-regulation of VEGF-binding HIF-1α. Anticancer Drugs (IF=2.407). 24:715-24. PMC3826813.
  28. Jiang B, Wang X, Gray ML, Duan Y, Luebke D, Li B*. (2013). Development of amino acid and amino acid-complex based solid sorbents for CO2 capture. Appl Energy (IF=5.011) 109:112-8.
  29. Wang X, Akhmedov NG, Duan Y, Luebke D, Li B*. (2013). Immobilize amino acid ionic liquid into nanoporous microspheres as robust sorbents for CO2 capture. J Mater Chem A 1(9):2978-82.
  30. Wang X, Akhmedov NG, Duan Y, Luebke D, Hopkinson D, Li B*. (2013). Amino acid- functionalized ionic liquid solid sorbents for post-combustion carbon capture. ACS Appl Mater Interfaces (IF=5.008). 5(17):8670-7.
  31. Li B*, Duan Y, Luebke D, Morreale B. (2013). Advances in CO2 capture technology: A patent review. Appl Energy (IF=5.011) 102:1439-47.
  32. Duan Y*, Pfeiffer H, Li B, Romero-Ibarra IC, Sorescu DC, Luebke DR, Halley JW. (2013).
  33. CO2 capture properties of lithium silicates with different ratios of Li2O/SiO2: an ab initio thermodynamic and experimental approach. Phys Chem Chem Phys (IF=3.573), 15(32):13538-58. PMID: 23824271.
  34. Boyce BM, Lindsey BA, Clovis NB, Smith ES, Hobbs GR, Hubbard DF, Emery SE, Barnett JB, Li B*. (2012). Additive effects of exogenous IL-12 supplementation and antibiotic treatment in infection prophylaxis. J Orthop Res (IF=3.112) 30(2):196-202. PMC3699881.
  35. Luo H, Jiang B, Li B*, Li Z, Jiang BH, Chen Y*. (2012). Kaempferol nanoparticles achieve strong and selective inhibition of ovarian cancer cell viability. Int J Nanomed (IF=4.976). 7:3951-9. PMC3410694.
  36. Duan Y*, Luebke DR, Pennline HW, Li B, Janik MJ, Halley JW. (2012). Ab initio thermodynamic study of the CO2 capture properties of potassium carbonate sesquihydrate, K2CO3·1.5H2O. J Phys Chem C (IF=4.805). 116(27):14461-70.
  37. Armstead AL, Li B*. (2011). Nanomedicine as an emerging approach against intracellular pathogens. Int J Nanomed (IF=4.976) 6:3281-93. PMC3252676.
  38. Li B*, McKeague AL. (2011). IL-12 nanocoatings and microcapsules prevent open fracture infections. Clin Orthop Relat Res (IF=2.065) 469(11):3262-5. PMC3183209.
  39. Jiang B, Kish V, Fauth DJ, Gray ML, Pennline HW, Li B*. (2011). Performance of amine- multilayered solid sorbents for CO2 removal: Effect of fabrication variables. Int J Greenhouse Gas Control (IF=5.111) 5;1170-5.
  40. Li B*, Jiang B, Fauth DJ, Gray ML, Pennline HW, Richards GA*. (2011). Innovative nano- layered solid sorbents for CO2 capture. Chem Comm (IF=5.50) 47;1719-21. PMID: 21127800.
  41. Zhao Q, Li H, Li B*. (2011). Nanoencapsulating living biological cells using electrostatic layer-by-layer self-assembly: platelets as a model. J Mater Res (IF=1.667) 26(2);347-51. PMC3045201.
  42. Zhao Q, Apopa PL, Schwegler-Berry D, Qian Y, Li B*. (2011). Human microvascular endothelial cells uptake nanoparticles. Biomaterials Forum 8-9.
  43. Jiang B, DeFusco E, Li B*. (2010). Polypeptide multilayer film co-delivers oppositely- charged drug molecules in sustained manners. Biomacromolecules (IF=4.502) 11(12);3630– 7. PMC3006044.
  44. Li H, Ogle H, Jiang B, Hagar M, Li B*. (2010). Cefazolin embedded biodegradable polypeptide nanofilms promising for infection prevention: A preliminary study on cell responses. J Orthop Res (IF=3.112) 28;992-9. PMC3699871.
  45. Li B*, Jiang B, Dietz MJ, Smith ES, Clovis NB, Rao KMK. (2010). Evaluation of local MCP-1 and IL-12 nanocoatings for infection prevention in open fractures. J Orthop Res (IF=3.112) 28;48-54. PMC3886371.
  46. Hamza T, Barnett JB, Li B*. (2010). Interleukin 12 a key immunoregulatory cytokine in infection applications. Int J Mol Sci (IF=1.387) 11;789-806. PMC2869233.
  47. Li B*, Jiang B, Boyce B, Lindsey B. (2009). Multilayer polypeptide nanoscale coatings incorporating IL-12 for the prevention of biomedical device-associated infections. Biomaterials (IF=7.365) 30;2552-8. PMC3699876.
  48. Jiang B, Li B*. (2009). Tunable drug incorporation and release from polypeptide multilayer nanofilms. Int J Nanomed (IF=2.612) 4;37-53. PMC2720742.
  49. Jiang B, Li B*. (2009). Polypeptide nanotechnology coatings for preventing dental and orthopaedic device-associated infection. J Biomed Mater Res B (IF=2.185) 88B(2);332-8. PMID: 18161817.
  50. Jiang B, Barnett JB, Li B*. (2009). Advances in polyelectrolyte multilayer nanofilms as tunable drug delivery systems (invited mini review). Nanotechnol Sci Appl 2;21-7. PMC3781750.
  51. Zhao Q, Li B*. (2008). pH-controlled drug loading and release from biodegradable microcapsules. Nanomedicine (IF=5.440) 4;302-10. PMC3699869.
  52. Likibi F, Jiang B, Li B*. (2008). Biomimetic nanocoating promotes osteoblast cell adhesion on biomedical implants. J Mater Res (IF=1.667) 23(12);3222-8.
  53. Li B, Rozas J, Haynie DT. (2006). Structural stability of polypeptide nanofilms under extreme conditions. Biotechnol Prog (IF=2.398) 22(1);111-7. PMID: 16454500.
  54. Zhong Y, Li B, Haynie DT. (2006). Fine tuning of physical properties of designed polypeptide multilayer films by control of pH. Biotechnol Prog (IF=2.398) 22(1);126-32. PMID: 16454502.
  55. Zhong Y, Li B, Haynie DT. (2006). Control of stability of polypeptide multilayer nanofilms by quantitative control of disulfide bond formation. Nanotechnology (IF=3.137) 17;5726-34.
  56. Li B, Haynie DT, Palath N, Janisch D. (2005). Nano-scale biomimetics: fabrication and optimization of stability of peptide-based thin films. J Nanosci Nanotechn (IF=1.435) 12(5);2042-9. PMID: 16430138.
  57. Haynie DT, Palath N, Liu Y, Li B, Pargaonkar N. (2005). Biomimetic nanotechnology: inherent reversible stabilization of polypeptide microcapsules. Langmuir (IF=3.898) 21(3);1136-8. PMID: 15667201.
  58. Zhang L, Li B, Zhi Z, Haynie DT. (2005). Perturbation of nanoscale structure of polypeptide multilayer thin films. Langmuir (IF=3.898) 21(12);5439-45. PMID: 15924473.
  59. Li B, Haynie DT. (2004). Multilayer biomimetics: reversible covalent stabilization of a nanostructured biofilm. Biomacromolecules (IF=4.502) 5(5);1667-70. PMID: 15360273.
  60. Li B, Mukasyan A, Varma A. (2003). Combustion synthesis of CoCrMo (F-75) implant alloy: microstructure and properties. Mater Res Innov (IF=1.723) 7(4);245-52.
  61. Varma A, Li B, Mukasyan A. (2002). Novel synthesis of orthopaedic implant materials. Adv Eng Mater (IF=1.761) 4(7);482-7.
  62. Li B, Rong LJ, Li YY, Gjunter VE. (2001). Electric resistance phenomena in porous Ni-Ti shape memory alloys produced by SHS. Scripta Materialia (IF=2.949) 44(5);823-7.
  63. Li B, Rong LJ, Li YY, Gjunter VE. (2000). Synthesis of porous Ni-Ti SMA by SHS: reaction mechanism and anisotropy in pore structure. Acta Materialia (IF=3.760) 48(15);3895-904.
  64. Li B, Rong LJ, Li YY, Gjunter VE. (2000). Fabrication of cellular NiTi intermetallic compounds. J Mater Res (IF=1.667) 15(1);10-3.
  65. Li B, Rong LJ, Li YY, Gjunter VE. (2000). A recent development in producing porous Ni-Ti shape memory alloys. Intermetallics (IF=2.231) 8(8);881-4.
  66. Li B, Rong LJ, Li YY, Gjunter VE. (2000). An investigation of the synthesis of Ti-50at%Ni alloys through combustion synthesis and conventional powder sintering. Metall Mater Trans A (IF=1.564) 31(7);1867-71.
  67. Li B, Rong LJ, Li YY, Gjunter VE. (2000). Porous Ni-Ti shape memory alloys produced by two different methods. Z Metallkd (IF=0.723) 91(4);291-5.
  68. Li B, Rong LJ, Li YY, Gjunter VE. (2000). Development of biomedical porous Ti-Ni shape memory alloys. Chinese J Mater Res (Chinese edition) 14(6);561-7.
  69. Li B, Rong LJ, Li YY. (2000). Stress-strain behavior of Ni-Ti intermetallics synthesized from powder sintering. Intermetallics (IF=2.231) 8(5-6);643-6.
  70. Li B, Rong LJ, Li YY. (2000). The influence of addition of TiH2 in elemental powder sintering porous Ni-Ti alloys. Mater Sci Eng A-Struct (IF=1.901) A281;169-75.
  71. Li B, Rong LJ, Luo XH, Li YY. (1999). Transformation behavior of sintered porous NiTi alloys. Metall Mater Trans A (IF=1.564) 30;2753-6.
  72. Li B, Rong LJ, Li YY, Gjunter VE. (1999). Deformation behavior of porous NiTi shape memory alloy and effect of thermal-mechanical cycling on shape memory property. Acta Metall Sin (IF=0.483) (Chinese edition) 35(4);362-4.
  73. Li B, Rong LJ, Li YY. (1999). Microstructure and superelasticity of porous NiTi alloy. Sci China Ser E 42(1);94-9 (in English) (IF=0.682). Sci China Ser E 29(1);11-5 (in Chinese).
  74. Li B, Rong LJ, Li YY. (1998). Porous NiTi alloy prepared from elemental powder sintering.
  75. J Mater Res (IF=1.667) 10(13);2847-51.
  76. Li B, Rong LJ, Li YY. (1998). Anisotropy of dimensional change and its corresponding improvement by addition of TiH2 during elemental powder sintering of porous NiTi alloy. Mater Sci Eng A-Struct (IF=1.901) A255;70-4.
Book Chapter
  1. Wang X, Li B*. (2015). Phase-change solvents for CO2 capture. In Book “Novel Materials for Carbon Dioxide Mitigation Technology (ISBN 9780444632593).” Fan S and Morreale B, Eds. Elsevier. P.3-22. DOI: http://dx.doi.org/10.1016/B978-0-444-63259-3.00001-X or http://www.sciencedirect.com/science/article/pii/B978044463259300001X.
  2. Wang X, Li B*. (2014). Electrospun nanofibrous sorbents and membranes for carbon dioxide capture. In Book “Electrospun Nanofibers for Energy and Environmental Applications (ISBN 978-3-642-54159-9).” Ding B and Yu J, Eds. Springer. P.249-63. DOI: 10.1007/978- 3-642-54160-5_10.
  3. Wang X, Duan Y, Li B*. (2012). Development and evaluation of fibrous adsorbents for carbon dioxide removal. In Book “Atmosphere and Climate: Physics, Composition/Dynamics and Health Impacts (ISBN 978-1-62417-433-9).” Wright A and Johnson S, Eds. Nova Science Publishers, Inc. NY, USA. P.83-98.
  4. Li H, Li B*. (2011). Platelet-rich plasma: its biological properties and applications. In Book “Advances in Condensed Matter and Materials Research, Volume 8 (ISBN 978-1-60876- 159-3).” Geelvinck H and Reynst S, Eds. Nova Science Publishers, Inc. NY, USA. P.53-73.
  5. Li   B*.    (2009).    Polypeptide    multilayer    films    and    microcapsules.    In    Book “Soft Nanomaterials (ISBN 1-58883-133-7).” Nalwa HS Ed. Vol. 2. American Scientific Publishers, Stevenson Ranch, CA. P.123-50.
  6. Li B*, Haynie DT. (2005). Chiral drug separation. In “Encyclopedia of Chemical Processing”. Lee S, Ed. Vol. 1, Taylor & Francis, New York. P.449-58.

   

     
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