Education

Biography

Ismail Kucukkurt is an Associate Professor in the Department of Biochemistry at the University of Afyon Kocatepe. Dr Kucukkurt completed his Ph.D. at Afyon Kocatepe University. His research interests lie in the area of saponins and some plants extract its antioxidant effects on tissue and organism. Also, he investigated obesity, effects of elements, especially boron, on tissue morphology, molecular and biochemical mechanism. He has collaborated actively with researchers in several other disciplines of biological science. He has taught biochemistry on undergraduate topics in veterinary medicine.

Research Interest

• Animal and Veterinary Sciences
• Biochemistry
• Hormones
• Oxidative Stress
• Lipid Peroxidation

Professional Activities:

Publications

1. R. Aslan, Y. Dündar, A. Eryavuz, A. Bülbül, I. Kucukkurt, A.F. Fidan, Z. Akıncı, "Effects of Different Dietary Levels of Yucca shidigera powder (deodorase) added to diets on performance, some hemotological and biochemical blood parameters and total antioxidant capacity of laying hens.", Revue de Médecine Vétérinaire, 156 (6), 350-355 pp. 2005.
2. G. Avcı, E. Kupeli, A. Eryavuz, E. Yesilada, I. Kucukkurt. "Antihypercholesterolaemic and antioxidant activity assessment of some plants used as remedy in Turkish Folk Medicine ." Journal of Ethnopharmacology. 107 (3), 418-423. pp. 2006.
3. H. Enginar, A. Eryavuz, G. Avcı, E. Kaya, I. Kucukkurt, A.F. Fidan, "Effect of Yucca schidigera extract on lipid peroxidation and antioxidant activity in rabbits exposed to γ-radiation", Revue de Médecine Vétérinaire,157 (8-9), 415-419 pp. 2006    
4. A. Eryavuz, G. Avcı, I. Kucukkurt, A.F. Fidan, "Comparison of Plasma Leptin, Insulin and Thyroid Hormone Concentrations and Some Biochemical Parameters Between Fat-Tailed and Thin-Tailed Sheep Breeds", Revue de Médecine Vétérinaire, 158 (5), 244-249 pp. 2007. 
5. A. Eryavuz, G. Avcı, H.A. Çelık, I. Kucukkurt. “Plasma Leptın, Insulın, Glucose and Urea Concentratıons throughout Lactatıon in Daıry Cows”. Bull Vet Inst Pulawy. 52 (3), 381-385. pp. 2008.
6. A.F. Fidan, İ.H. Ciğerci, N. Baysu-Sozbilir, I. Kucukkurt, H. Yuksel, H. Keleş. "The Effects of the Dose-dependent γ-Hexachlorocyclohexane (Lindane) on Blood and Tissue Antioxidant Defense Systems, Lipid Peroxidation and Histopathological Changes in Rats", Journal of Animal and Veterinary Advances, 7 (11), 1480-1488 pp. 2008.
7. I. Kucukkurt, S. Ince, A.F. Fidan, A. Ozdemır. "The Effects of Dietary Supplementation of Different Amount of Yucca schidigera Powder (Sarsaponin 30®) on Blood and Tissue Antioxidant Defense Systems and Lipid Peroxidation in Rats", Journal of Animal and Veterinary Advances, 7 (11), 1413-1417 pp. 2008.
8. N. Öztaşan, A. Bülbül, A. Eryavuz, G. Avcı, I. Kucukkurt, A. F. Fidan, "Effect of Yucca schidigera extract on blood pressure, antioxidant activity and some blood parameters in the L-name-induced hypertensive rats", Ankara Üniversitesi Veteriner Fakültesi Dergisi, 55 (3), 149-153 pp. 2008.
9. A.F. Fidan, İ.H. Ciğerci, M. Konuk, I. Kucukkurt, R. Aslan, Y. Dündar. "Determination of Some Heavy Metal Levels and Oxidative Status in Carassius carassius L. 1758 from Eber Lake", Environmental Monitoring and Assessment, 147 (1-3), 35–41 pp. 2008.
10. İ.S. Çetingul, M. Yardimci, E.H. Sahin, İ. Bayram, I. Kucukkurt, A.B. Akaya. “The effects of hazelnut oil usage on live weight, carcass, rumen, some blood parameters and femur head ash in Akkaraman lambs.” Meat Science. 83 (4), 647-650 pp. 2009.
11. A.F. Fidan, I. Kucukkurt, A. Ozdemır, H. Yuksel, S. Ince, Y. Dündar. "The Effects of Structurally Different Saponin Containing Plants on Tissue Antioxidant Defense Systems, Lipid Peroxidation and Histopathological Changes in Streptozotocin-Induced Diabetic Rats". Journal of Animal and Veterinary Advances, 8 (5), 920-927 pp. 2009.
12. A.F. Fidan, I. Kucukkurt, A. Eryavuz, İ.H. Ciğerci, M. Yardimci, A. Ozdemır. "Effects of shearing procedures on oxidant-antioxidant status in Chios sheep", Revue de Médecine Vétérinaire, 160 (7), 349-355 pp., 2009
13. İ.H. Ciğerci, A.F. Fidan, M. Konuk, H. Yüksel, I. Kucukkurt, A. Eryavuz, N. Bayşu Sözbilir. "The Protective Potential of Yucca schidigera (Sarsaponin 30®) against Nitrite-Induced Oxidative Stress in Rats", Journal of Natural Medicines. 63 (3), 311-317 pp. 2009.
14. A.E. Küpeli, G. Avcı, I. Kucukkurt, H. Keles, U. Tamer, S. İnce, E. Yesilada. “Cholesterol-reducer, antioxidant and liver protective effects of Thymbra spicata L. var. Spicata”. Journal of Ethnopharmacology. 126 (2), 314-319. pp. 2009.
15. G. Avcı, I. Kucukkurt, E. Küpeli Akkol, E. Yeşilada. “Effects of Escin Mixture from the Seeds of Aesculus Hippocastanum on Obesity in Mice Fed on High-Fat Diet”. Pharmaceutical Biology. 48 (3), 247-252. pp. 2010.
16. H. Keles, A.F. Fidan, İ.H. Ciğerci, I. Kucukkurt, E. Karadas, Y. Dündar. "Increased DNA damage and oxidative stress in chickens with Natural Marek's Disease." Veterinary Immunology and Immunopathology”. 133 (1), 51-58 pp. 2010.
17. S. Ince, I. Kucukkurt, İ.H. Cigerci, A.F. Fidan, A. Eryavuz. "The effects of dietary boric acid and borax supplementation on lipid peroxidation,antioxidant activity, and DNA damage in rats.", Journal of Trace Elements in Medicine and Biology.” 24 (3),161-164 pp. 2010.
18. S. Ince, I. Kucukkurt, İ. Aytekin, E. Bacak. “Short-Term Effect of Deltamethrin Treatment on Oxidative Stress Biomarkers in Anatolian Water Buffaloes”. Asian Journal of Animal and Veterinary Advances. 5 (4), 266-270. pp. 2010.
19. S. Ince, E. Kozan, I. Kucukkurt, E. Bacak. “The effect of levamisole and levamisole + vitamin C on oxidative damage in rats naturally infected with Syphacia muris.” Experimental Parasitology. 124 (4), 448-452. pp. 2010.
20. I. Kucukkurt, S. Ince, H. Keleş, E.A. Küpeli, G. Avcı, E. Yeşilada, E. Bacak. “Beneficial effects of Aesculus hippocastanum seed extract on the bodys own antioxidant defense system on subacute administration”. Journal of Ethnopharmacology. 129 (1), 18-22. pp. 2010.
21. G. Avcı, C. Uğuz, İ. Bayram, M. Erdoğan, I. Kucukkurt, M. Dosay Akbulut, M. Özdemir, Ö.F. Lenger, M. İşcan, İ. Togan. “Effects of Nonylphenol on Growth Parametersand Antioxidant Defense System in Japanese Quails (Coturnix japonica).” Kafkas Univ Vet Fak Derg. 16 (4), 537-546. pp. 2010.
22. I. Kucukkurt, S. Ince, H. Enginar, A. Eryavuz, A.F. Fidan, M. Kargıoglu. “Protective effects of Agrostemma githago L. and Saponaria officinalis L. extracts against ionizing radiation-induced oxidative damage in rats.” Revue de Médecine Vétérinaire, 162 (6), 289-296 pp., 2011.
23. H. Keleş, S. İnce, I. Kucukkurt, İ.İ. Tatlı, E.K. Akkol, Ç. Kahraman, H.H. Demirel. “The effects of Feijoa sellowiana fruits on the antioxidant defense system, lipid peroxidation, and tissue morphology in rats.” Pharmaceutical Biology. 50 (3), 318-325. pp. 2012.
24. G. Avci, I. Kucukkurt, Y.O. Birdane, A. Eryavuz, M. Ozdemir. “Influence of high dietary nitrate intake and sulphur supplementation on oxidant / antioxidant balance and on some haematological parameters in angora goats.” Revue de Médecine Vétérinaire, 163 (2), 76-78 pp., 2012.
25. S. Ince, H. Keles, M. Erdogan, O. Hazman,  I. Kucukkurt. “Protective effect of boric acid against carbon tetrachloride-induced hepatotoxicity in mice.” Drug and Chemical Toxicology. 35 (3), 285-292 pp. 2012.
26. S. İnce, I. Kucukkurt, H.H. Demirel, R. Turkmen, E. Sever. “Thymoquinone attenuates cypermethrin induced oxidative stress in Swiss albino mice.” Pesticide Biochemistry and Physiology. 104 (3), 229-235 pp. 2012.
27. G. Avcı, I. Kucukkurt, T. Kontaş, A. Eryavuz, A.F. Fidan. “Farklı ırk koyunlarda rasyona çinko ilave edilmesinin plazma leptin, insulin ve tiroid hormon düzeyleri ile bazı biyokimyasal parametreler üzerine etkisi.” Ankara Üniversitesi Veteriner Fakültesi Dergisi. 60 (1), 1-5 pp. 2013.
28. S. İnce, I. Kucukkurt, H.H. Demirel, R. Turkmen, F Zemheri, E. Akbel. “The role of thymoquinone as antioxidant protection on oxidative stres induced by imidacloprid in male and female Swiss albino mice.” Toxicological and Environmental Chemistry. 95 (2), 318-329 pp. 2013.
29. S. İnce, I. Kucukkurt, H.H. Demirel, R. Turkmen, E. Sever. “Dietary Yucca schidigera supplementation reduces arsenic-induced oxidative stress in Swiss albino mice.” Toxicology and Industrial Health. 29 (10) 904-914 pp. 2013.
30. I. Kucukkurt, Y. Dündar. Effects of dietary Yucca schidigera supplementation on plasma leptin, insulin, iodated thyroid hormones and some biochemical parameters in rats. Revue Méd. Vét., 164 (7) 362-367 pp. 2013.
31. I. Kucukkurt, İ.H. Cigerci,  S. Ince, E Kozan, I Aytekin, A. Eryavuz, A.F. Fidan. The Effects of Babesiosis on Oxidative Stress and DNA Damage in Anatolian Black Goats Naturally Infected with Babesia ovis. Iranian J Parasitol, 9 (1), 90-98 pp. 2014.
32. S. Ince, I. Kucukkurt, H.H. Demirel, D.A. Acaröz, E. Akbel, İ.H. Cigerci. Protective effects of boron on cyclophosphamide induced lipid peroxidation and genotoxicity in rats. Chemosphere, 108, 197-204 pp. 2014.
33. M. Özdemir, A. Eryavuz, G. Avcı, Y.O. Birdane, I. Kucukkurt. Effects of supplementation of inorganic sulfur on some biochemical parameters in Angora goat’s diet containing high nitrate levels. Turk J Vet Anim Sci. 38, 526-533 pp. 2014.
34. S. İnce, D.A. Acaröz, O. Neuwirth, H.H. Demirel, B. Denk, I. Kucukkurt, R. Türkmen.  Protective effect of polydatin, a natural precursor of resveratrol, against cisplatin-induced toxicity in rats. Food and Chemical Toxicology. 72, 147-153 pp. 2014.
35. I. Kucukkurt, E. Akbel, F. Karabağ, S. İnce. “The Effects of Dietary Boron Compounds in Supplemented Diet on Hormonal Activity and Some Biochemical Parameters in Rats.” Toxicology and Industrial Health. 31 (3), 255-260 pp. 2015.
36. F.K. Çoban, S. İnce, İ Küçükkurt, H.H. Demirel, Ö. Hazman. “Boron attenuates malathion-induced oxidative stress and acetylcholinesterase inhibition in rats.” Drug Chem Toxicol,; 38(4): 391–399 pp. 2015.
37. I. Kucukkurt, S. Ince, H.H. Demirel, R. Turkmen, E. Akbel, Y. Celik. “The Effects of Boron on Arsenic-Induced Lipid Peroxidation and Antioxidant Status in Male and Female Rats.” Journal of Biochemical and Molecular Toxicology. 29, 12 564–571 2015.
38. I. Kucukkurt, E.K. Akkol, F.K. Çoban, S. İnce, İ. Süntar, A. Eryavuz, N.B. Sözbilir. “Determination of the regulatory properties of Yucca schidigera extracts on the biochemical parameters and plasma hormone levels associated with obesity.” Revista Brasileira de Farmacognosia. In press. 2016.
39. H.A. Çelik, G. Avcı, A. Bülbül, İ. Aydın, I. Kucukkurt. “İneklerde seksüel siklusun çeşitli evrelerinde dominant ve sekonder follikül sıvılarında oksidan antioksidan dengenin izlenmesi.” Hayvancılık Araştırma Dergisi. S: 7-13, 2006.
40. N. Oztasan, Y. Ocak, I. Kucukkurt, L. Akgün, A. Eryavuz. “Effects of Football Matches on Lipid Peroxidation and Antioxidant in Blood of Soccers.” Egzersiz Çevirimiçi Dergi, 1 (2), S: 19-23. 2007.
41.  G. Avcı, I. Kucukkurt, T. Kontaş, A. Eryavuz, A.F.Fidan, “Tavşanlarda Rasyona İlave Edilen Farklı Miktarlardaki Yucca schidigera Ekstraktının (De-Odorase®) Bazı Serum Makro ve Mikro Element Düzeylerine Etkisi”, F.Ü.Sağ.Bil.Vet.Derg ,21 (6), S: 257 – 262,  2008.
42. G. Avcı, I. Kucukkurt, A.F. Fidan, A. Eryavuz, R. Aslan, Y. Dündar. “Nakil İşlemine Tabi Tutulan Koyunlarda Vitamin C ve Ksilazin Uygulamasının Kortizol ve Lipid Peroksidasyon ile Bazı Biyokimyasal Parametrelere Etkisi”, F.Ü.Sağ.Bil.Vet.Derg., 22 (3), S: 147-152, 2008.
43. I. Kucukkurt, A.F. Fidan, “Saponinler ve Bazı Biyolojik Etkileri”, Kocatepe Veterinary Journal, 89-96 pp. 2008.
44. I. Kucukkurt, G. Avci, A. Eryavuz, İ. Bayram, İ.S. Çetingul, A.B. Akkaya, C. Uyarlar. “Effects of Supplementation of Aniseed (Pimpinella anisum L.) at Various Amounts to Diets on Lipid Peroxidation, Antioxidant Activity and Some Biochemical Parameters in Laying Quails (Coturnix coturnix japonica).” Kocatepe Veterinay Journal, 2 (1), S: 1-5, 2009.
45. A.F. Fidan, I. Kucukkurt, N. Bayşu Sözbilir, A. Eryavuz, İ. Bayram, İ.S. Çetingül, M. Yardimci, “Effects of supplementation of poopy seed and poopy seed oil at various quantities on oxidant-antioxidant balance in laying hens”, Kocatepe Veterinary Journal, 3 (1), S: 1-5, 2010.
46. I. Kucukkurt, S. Ince, I. Aytekin, Y.O. Birdane. The effects of flumethrin and flumethrin+vitamin C application on oxidative stress biomarkers in Chios sheep. Kocatepe Veterinary Journal, 3 (2): 13-17 pp. 2010
47. C. Çevik, A. Eryavuz, E. Ulutaş, I. Kucukkurt, A. Bülbül, H.H. Demirel, N. Taşkıran, R. Aslan. “Ratlarda kaplıca suyu ve kaplıca suyu ile birlikte C vitaminin uzun süre tüketilmesinin oksidan antioksidan denge ve bazı biyokimyasal parametreler üzerine etkisinin belirlenmesi.” Kocatepe Veterinary Journal, 4 (2), 23-32 pp. 2011.
48. I. Kucukkurt. “The Effects of Leptin on Other Hormones.” Kocatepe Veterinary Journal, 8 (1), 75-83 pp. 2015.
49. A. Eryavuz, I. Kucukkurt, S. İnce, A.F. Fidan, G. Avcı, T. Bülbül (2015). “Effects of supplementation of Yucca schidigera to diet and its dailydose on somerumen and blood parameters, live weight gain in lambs.” Kocatepe Veterinary Journal, in press.