nir-yakoby
Nir Yakoby, PhD
Associate Professor of Biology

Rutgers University
Camden, New Jersey, USA
Phone: (856) 225-6150
E-mail: yakoby@camden.rutgers.edu

Education

 1994  BSc in Plant Protection Hebrew University of Jerusalem, Jerusalem, Israel
 2001  PhD in Plant-Microbe Interact Hebrew University of Jerusalem, Jerusalem, Israel
 2004  Postdoctoral in Protein Biotech Rutgers University, New Jersey, USA
 2008 Postdoctoral in Developmental Biology Princeton University, New Jersey, USA

Biography

Dr. Nir Yakoby is an Associate Professor at the Biology Department, Rutgers, The State University of New Jersey, Camden. Currently, he serves as the Director of the Center for Computational and Integrative Biology (CCIB) at Rutgers Camden. He received his BSc and PhD from the Hebrew University, Israel. The research in his laboratory is using genetic, molecular, and computational approaches to study cell signaling, tissue patterning, and morphogenesis of the Drosophila eggshell.


Research Interest

  • Cell to cell signaling (EGFR, BMP, JAK-STAT)
  •  Drosophila oogenesis
  •  Tissue patterning
  •  The evolution of Drosophila eggshell
  •  Mechanisms underlying the evolution of morphologies

Scientific Activities

Academic Positions
2016-Present Director, Center for Computational and Integrative Biology (CCIB), Rutgers University, New Jersey, USA
2014-2016 Graduate Program Director, Center for Computational and Integrative Biology (CCIB), Rutgers University, New Jersey, USA
2014-Present Associate Professor, Biology Department, Rutgers University, Camden, New Jersey, USA
2008-2014 Assistant Professor, Biology Department, Rutgers University, Camden, New Jersey, USA
2010-Present Adjunct Faculty Member of the Graduate School of Biomedical Sciences at School of Osteopathic Medicine, Rowan University, New Jersey, USA
Professional Activities
2015-Present The Society for Developmental Biology
2005-Present The Genetics Society of America
2010 The American Society for Cell Biology
Honors & Awards
2014 The Rutgers University Board of Trustees Research Fellowship for Scholarly Excellence
2012 NSF-CAREER Award IOS-1149144
2007 Postdoctoral poster award, Genetics Society of America, 48th Drosophila Annual Meeting
2000 Vaadia-BARD Postdoctoral Fellow, number FI-302-2000
1999 Outstanding Student Lecture, Israel Phytopathological Society 20th Convention
1998-2000 Future Leadership in Orchards, The Fruit Board of Israel and Agricultural Ministry
1998 Avigad and his daughter Dovrat. The Association of Trustees and Friends of Agricultural Research at the Volcani Center
1996 Yehuda Horin, The Association of Trustees and Friends of Agricultural Research at the Volcani Center
1995 The Fruit Board of Israel Award

Publications

  1. N. Revaitis, R.A. Marmion, M. Farhat, V. Ekiz, W. Wang, N. Yakoby. Simple expression domains are regulated by discrete CRMs during Drosophila oogenesis. 2017. G3 7:2705-2718; early online June 20, 2017.
  2. G. Pyrowolakis, V. Veikkolainen, N. Yakoby, S.Y. Shvartsman. Gene regulation during Drosophila eggshell patterning. 2017. PNAS Jun 6;114(23):5808-5813. 
  3. F. Rossi, N.P. Duteil, N. Yakoby, B. Piccoli. Control of reaction-diffusion equations on time-evolving manifolds. 2016. Decision and Control (CDC), IEEE 55th Conference on, 1614-1619.
  4. F. Rossi, N. PouradierDuteil, N. Yakoby, B. Piccoli: Control of reaction-diffusion equations on time-evolving manifolds, Proceedings of the IEEE Conference on Decision and Control 2016, Las Vegas, NV, 2016.
  5. M.G. Niepielko, N. Yakoby. Evolutionary changes in TGF-alpha distribution underlie morphological diversity in Drosophila eggshells. 2014. Development 15;141(24):4710-4715.
  6. M.G. Niepielko, R. A. Marmion, K. Kim, D. Luor, C. Ray, N. Yakoby. Chorion Patterning: A window into gene regulation and Drosophila species-relatedness. 2014. Molecular Biology & Evolution. 31 (1):154-164.
  7. R.A. Marmion, M. Jevtic, A. Springhorn, G. Pyrowolakis, and N. Yakoby. The Drosophila BMPRII, Wishful thinking, is required for eggshell patterning. 2013. Developmental Biology. 375:45-53.
  8. M.G. Niepielko, K. Ip, J.S. Kanodia, D. Lun, and N. Yakoby. The evolution of BMP signaling in Drosophilaoogenesis: a receptor-based mechanism. 2012. Biophysical Journal. 102:1722-1730.
  9. J.J. Zartman, L.S. Cheung, M.G. Niepielko, C. Bonini, B. Haley, N. Yakoby, and S.Y. Shvartsman. Pattern formation by a moving morphogen source. 2011. Physical Biology. Aug;8(4):045003. Epub 2011 Jul 12.
  10. M.G. Niepielko, Y. Hernáiz-Hernández, and N. Yakoby. BMP signaling dynamics in the follicle cells of multiple Drosophila species. 2011. Developmental Biology. 354:151-159.
  11. J. Lembong, N. Yakoby, and S.Y. Shvartsman. Modeling of epithelial patterning by interacting signaling pathways. 2009. PNAS. 9:3213-3218.
  12. J.J. Zartman, J.S. Kanodia, N. Yakoby, X. Schafer, C. Watson, K. Schlichting, C. Dahmann and S.Y. Shvartsman. Expression patterns of cadherin genes in Drosophila oogenesis. 2009. Gene Expression Patterns. 9(1):31-36
  13. J. J. Zartman, N. Yakoby, C. A. Bristow, X. Zhou, K. Schlichting, K. Dahmann, and S. Y. Shvartsman. Cad74A is regulated by BR and is required for robust dorsal appendage formation in Drosophila oogenesis. 2008. Developmental Biology. 322:289-301.
  14. N. Yakoby, C.A. Bristow, D. Gong, X. Schafer, J. Lembong, J.J. Zartman, M. Halfon, T. Schupbach, and S.Y. Shvartsman. A combinatorial code for pattern formation in Drosophila oogenesis. 2008. Developmental Cell. 15:725-737.
  15. J. Lembong, N. Yakoby, and S.Y. Shvartsman. Spatial regulation of BMP signaling by patterned expression. 2008. Tissue Engineering. 14:1469-1477.
  16. N. Yakoby, J. Lembong, T. Schüpbach, and S. Y. Shvartsman. Drosophila eggshell is patterned by sequential action of feedforward and feedback loops. 2008. Development. 135:343-351.
  17. S. Komarnytsky, N. Borisjuk, N. Yakoby, A. Garvey, and I. Raskin. Co-secretion of proteinase inhibitor stabilizes antibodies produced by plant roots. 2006. Plant Physiology. 141:1185-1193.
  18. N. Yakoby, A.S., Garvey, and I. Raskin. Tobacco ribosomal DNA spacer element enhances BBI expression in tomato plants. 2006. Plant Cell Reports. 25:573-581.
  19. L.A. Goentoro, N. Yakoby, J. Goodhouse, T. Schüpbach, and S.Y. Shvartsman. Fluorescence-based quantitative analysis of GAL4/UAS systems in Drosophila oogenesis. 2006. Genesis. 44:66-74.
  20. N. Yakoby, C.A. Bristow, I. Gouzman, M.P. Rossi, Y. Gogotsi, T. Schüpbach, and S.Y. Shvartsman. Systems-level questions in Drosophila oogenesis. 2005. IEE Systems Biology. 152:169-302.
  21. N. Yakoby, and I. Raskin. A simple method to determine trypsin and chymotrypsin inhibitory activity. Journal of Biochemical and Biophysical Methods. 2004. 59:241-251.
  22. D. Prusky, and N. Yakoby. Pathogenic fungi: leading or led by ambient pH? Molecular Plant Pathology. 2003. 6:509-516.
  23. I. Raskin, D.M. Ribnicky, S. Komarnytsky, N. Ilic, A. Poulev, N. Borisjuk, A. Brinker, D.A. Moreno, C. Ripoll, N. Yakoby, J.M O’Neal, T. Cornwell, I. Pastor, and B. Fridlender. Plants and human health in the twenty-first century. Trends in Biotechnology. 2002. 12:522-531.
  24. N. Yakoby, D. Beno-Moualem, I. Kobiler, and D. Prusky. The analysis of fruit protection mechanisms provided by reduced pathogenicity mutants of Colletotrichumgloeosporioidesobtained by restriction enzyme mediated integration. Phytopathology. 2002. 92:1196-1201.
  25. N. Yakoby, D. Beno-Moualem, N. T. Keen, A. Dinoor, O. Pines, and D. Prusky.
    ColletotrichumgloeosporioidespelB is an important virulence factor in avocado fruit fungus interactions. Molecular Plant Microbe Interactions. 2001. 14:988-995.
  26. D. Prusky, D. Eshel, I. Kobiler, N. Yakoby, D. Beno-Moualem, M. Akerman, Y. Zuthi, and R. Ben Arie. Post-harvest chlorine treatments for the control of the persimmon black spot disease caused by AlternariaAlternata. Post-harvest Biology and Technology. 2001. 22:271-277.
  27. N. Yakoby, R. Zhou, I. Kobiler, A. Dinoor, and D. Prusky. Development of Colletotrichumgloeosporioides restriction enzyme mediated integration mutants as biocontrol agents against anthracnose disease in avocado fruit. Phytopathology. 2001. 91:143-148.
  28. N. Yakoby, S. Freeman, A. Dinoor, N.T. Keen, and D. Prusky. Expression of pectate lyase from Colletotrichumgloeosporioidesin C. magna promotes pathogenicity. Molecular Plant Microbe Interactions. 2000. 13:887-891.
  29. N. Yakoby, I. Kobiler, A. Dinoor, and D. Prusky. pH regulation of pectate lyase secretion modulates the attack of Colletotrichumgloeosporioides on avocado fruits. Applied and Environmental Microbiology. 2000. 66:1026-1030.

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