Education

Profile

Prof.Dr. Sermin Tetik has received his PhD in Marmara University during the period of 2003. Currently, she is working as a researcher and an academic person at the same University. She has successfully completed her administrative responsibilities as an advisor of several PhD and MSc students. Her research has included thrombosis, hemostasis and angiology and proteomics based on this research and fellowship training she has received several awards and honors, such as scientific research award, International publishing award. She is serving as an editorial member of several reputed journals like Advances in Biochemistry, American Journal of Life Sciences. She have one of the authored Clinical Biochemistry book. She is a member of ISTH.

Research Interest

Pharmaceutical sciences, Thrombosis and hemostasis, Clinical research, proteomics, pathophysiology of several diseases, biomarkers on cardiovascular diseases, analytical and instrumental approach for biomarker discovery, mass spectrometry

Professional Activities:

Honors and Awards

Publications

1. Sehirli, A.O., Cetinel, S., Ozkan, N., Selman, S., Tetik, S., Yuksel, M., Dulger, F.G. (2015): St.John’s Wort may ameliorate 2,4,6-trinitrobenzenesulfonic acid colitis of rats throgh the induction of pregnane X receptors and/or p-glycoproteins.   Journal of physiology and pharmacology:   66(2), 203-214.
2. Ozakpınar, O.B., Sahin, S., Verimli, N., Simsek, G.G., Maurer, A.M., Eroğlu, M., Tetik, S., Uras, F. (2015): Association between the growth arrest-specific 6 (Gas6) gene polymorphism c.834 + 7G>A and preeclampsia. J Matern Fetal Neonatal Med. 27:1-5.
3. Tetik, S., Kılıç, A., Ahmad, S., Aksoy, H., Yardımcı, K.T. (2015): Oxidative stress causes plasma protein modification. IJEB, 53, 25-30.
4. Sehirli, A.O., Tetik, S.,Yiginer, O.,  Çetinel, S., Özkan, N.,  Akkiprik, M., Kaya, M.,  Yeğen, B.C.,  Tezcan, M.,  Aykaç, A., Şener, G.Alterations in Cardiac Caveolin-3 Expression and Na/K ATPase Activity in Rats with Myocardial Infarction Are Reversed by Resveratrol. The American Journal of Cardiology 2015;15, Supplement 1,Pages, S8-S9
5. Sahin, S.,  Ozakpınar, O.B., Eroglu, M.,Tulunay, A., Çıracı E., Uras, F., Tetik, S. (2015): The impact of platelet functions and inflammatory status on the severity of preeclampsia J Maternal-Fetal&Neonatal Medicine, 28(6), 643-648.
6. Syed, D., Jezovnik, M., Poredos, P., Hoppensteadt, D., Tetik, S., Iqbal, O., Kalodiki, E. (2014): Circulating levels of Rivaroxaban provide different results in different clot based and amidolytic assays. A study of 106 patients treated with two different dosing of Rivaroxaban. A J Hematology, 89(6), E72-E73.
7. Mateja, J., Daneyal, S.,  Tetik, S.,  Hoppensteadt, D.,  Pavel, P., Jawed, F.  (2014): Comparison of local and systemic inflammatory, fibrinolytic and hemostatic parameters in patients with varicose veins.  AJ Hematology, 89(6), E39-E40.
8. Hoppensteadt, D., Syed, D.,  Jezovnik, M.,  Poredos, P., Tetik, S., Iqbal, O., Walenga,J.M.   Fareed. J. (2014): Circulating Levels of Rivaroxaban Provide Different Results in Different Clot Based and Amidolytic Assays. A Study on Patients Treated with Two Different Dosages of Rivaroxaban. Blood, 124(21), 5084-5084.
9. Sahin, S., Ozakpinar, O.B., Ak, K., Eroglu, M., Açikel, M., Tetik ,S., Uras, F, Cetinel, S. (2014): The protective effects of tacrolimus on rat uteri exposed to ischemia-reperfusion injury: a biochemical and histopathologic evaluation.  Fertil Steril, 101(4), 1176-1182.
10. Sehirli, A.O., Koyun, D.,  Tetik, S., Ozsavci, D.,Yiginer, O., Cetinel, S., Tok, O.E., Kaya, Z., Akkiprik, M., Kilic, E., Sener, G. (2013): Melatonin protects against ischemic heart failure in rats. J. Pineal Res, 55(2), 138-148
11. *Tetik, S., Kaya, K., Yardimci, K.T. (2011): Effect of Oxidized Fibrinogen on Haemostatic System: in vitro Study. Clin Appl Thromb Hemost, 17(3), 259-63.
12. *Tetik, S., Ak, K., Sahin, Y., Isbir, S., Gulsoy, O., Arsan, S., Yardimci, K.T. (2011): Postoperative statin therapy attenuates the intensity of systemic inflammation and increases fibrinolysis after coronary artery bypass grafting. Thromb hemost Clin Appl, 17(5), 526-31
13. Ersahin, M., Toklu, H.Z., Erzik, C., Akakın, D., Tetik, S., Sener, G., Yegen, B.C. (2011): Ghrelin alleviates spinal cord injury in rats via its anti-inflammatory effect. T Neurosurgery, 21, 599-605
14. Tetik, S., Ermengu, E., Ak, K., Tekkeşin, N., Ahmad, S., Yardımcı, K.T. (2013). Evaluations of Haemostatic    Alterations in Coronary Artery Bypass Graft Patients Before and After Angiography Using Thrombelastography. Curr Trend in Biotech Pharm, 7, 492-498. 
15. Ak, E., Dulger, E.C.,  Sehirli, A.O., Tetik, S., Pisiriciler, R., Sener, G., Cetinel, S. (2015): Effect of oxytocin on rat urinary applicated stress of running away from water: Evaluation by light and electron microscopy. Marmara Pharmaceutical Journal, 19,19-26. 
16. Tetik S. Protective effect of betaine against burn induced pulmonary injury in rats. Turkish Journal of Trauma & Emergency Surgery. (UTD-60137, ACCEPTED FOR PUBLICATION, 2015-10-27)
17. Tekkesin, N., Ardal, H., Tetik, S. (2014): The Frequency of Aspirin Resistance and Its Relationship with Clinical and Laboratory Parameters in Patients with Stable Coronary Artery Disease. Clinical of Turkey  J Med Sci 2014;34(4):363-72 (İngilizce)
18. Sahin, S., Ozakpinar, O.B., Eroglu, M., Tetik, S.  (2014): Platelets in Preeclampsia: Function and Role in the Inflammation. MUSBED, 4(2), 111-116.
19. Silay, M.S., Toklu, H.Z., Ozagari, A., Aydin, M., Tetik, S., Sener, G., Miroglu, C., Kendirci, M. (2014): Montelukast prevents testes against ischemia-reperfusion injury through suppression of iNOS expression. Turkish Journal of Urology, 40(4), 221-227
20. Sahin, S., Ozakpinar, O.B.,Tulunay, A., Eroglu, M.,Ciraci, E.,Tetik, S., Uras, F. (2014): Cytokine Levels and Platelet Functions in Preeclampsia. MUSBED, Volume 133, Supplement 3, Page S113.
21. Sahin, S., Eroglu, M., Tetik, S., Guzin, K. (2014): Disseminated intravascular coagulation in obstetrics: Etiopathogenesis and up to date management strategies  J Turk Soc Obstet Gynecol, 11(1), 42-51.
22. Sahin, S., Eroglu, M., Ozakpinar, O.B., Tulunay,A. Konukcu, B., Tetik, S. (2013): Evaluation of Platelet Aggregation by Aggregometry in         Preeclamptic Women. Zeynep Kamil Med Bulletin, 44(3), 111-5.
23. Ergün, I.S., Tetik, S. (2012): Isolation and Polymorphism of Platelet Glycoprotein IIb/IIIa Receptor in Breast Cancer Cases. MUSBED, 3(2), 49.
24. Tetik,  S., Ozaltun, K., Ozakpinar, O.B., Disbudak, M., Rizaner, N., Yavuz, S., Yardimci K.T. (2011): in vivo effect of cholchicine, colchine and anti-agregating agent on protein oxidation in Behcet’s diseases. Cumhuriyet Med J, 33, (4): 435-442.
25. Sehirli, O., Unlu, B., Cetinel, S., Tetik, S., Sener, E., Sener, G. Etanercept protects remote organ damage in a rat model of thermal injury. Marmara Pharmaceutical Journal 2011;3(15):118-124.
26. Tetik, Ş., Ak, K., Yardımcı, K.T. (2012): Factors which have  effected test of platelet functions  Cumhuriyet Med J, 34, 123-127
27. Tetik, S. (2012): To be a Pharmacist in North Cyprus. Pharmacist Journal, 90, 25.

Chapter of Book

28. Tetik, S. (2015): Biochemistry of cardiovascular diseases.  Clinical Biochemistry Book.  Eds: Prof.Dr. Nesrin Emekli, Assoc.Prof.Dr. Turkan Yigitbası. Chapter 19 , page199-208. Nobel Med Publish
29. Sehirli, A.O., Tetik, S.,Yiginer, O.,  Çetinel, S., Ozkan, N.,  Akkiprik, M., Kaya, M.,   Yegen, B.C.,  Tezcan, M., Aykac, A., Sener, G. Alterations in Cardiac Caveolin-3 Expression and Na/K ATPase Activity in Rats with Myocardial Infarction Are Reversed by Resveratrol. The American Journal of Cardiology 2015;26-29 March, OP-022.
30. Tetik, S. Sample preparation of Mass Spectrometry. International Summit on Current Trends in Mass Spectrometry. July 13-15, 2015 New Orleans, USA
31. Tetik, S. Overview of Mass Specrometry. International Summit on Current Trends in Mass Spectrometry. July 13-15, 2015 New Orleans, USA
32. Tetik, S. The Ethics of Evolution by Design. 3Rd International Gen-Arel Molecular Biology and Genetic Student Congress, Istanbul Arel University, Sefakoy Campus, 24-25 April 2015. 
33. Low, C.,  Syed, D., Khan, D., Tetik, S., Hoppensteadt, D., Mosier, M., Fareed, J. Modulation of Interleukins in Sepsis Associated Coagulopathy: Interplay with Thrombosis. 2014 American Society for Clinical Investigation(ASCI)/Association of American Physicians(AAP) Joint Meeting, April 25-27, Chicago, Illinois.
34. Mateja, J., Daneyal, S.,  Tetik, S., Hoppensteadt, D., Poredos, P., Fareed, J. Comparison of local and systemic inflammatory, fibrinolytic and hemostatic parameters in patients with varicose weins,  10-12 April 2014 Thrombosis Hemostasis, Chicago,IL US.
35. Syed, D., Jezovnik, M., Poredos, P., Hoppensteadt, D., Tetik, S., Iqbal, O., Kalodiki, E. Circulating levels of Rivaroxaban provide different results in different clot based and amidolytic assays. A study of 106 patients treated with two different dosing of Rivaroxaban, 10-12 April 2014 Thrombosis Hemostasis, Chicago,IL US ISSN:0361-8609.
36. Ozakpinar, O.B., Sahin, S., Verimli, N., Eroğlu, M., Tetik, S., Uras, F. The growth arrest-spesific 6 (GAS6) gene polymorphism c.834+7G>A associated with preeclampsia. 23rd Biennial International MLTD Congress, 14-17 Mayıs 2014, Valencia, Spain.
37. Sahin, S., Ozakpinar, O.B., Tulunay, A., Eroglu, M.,  Ciraci, E.,  Uras, F.,  Tetik, S.  Cytokine Levels and Platelet Functions in Preeclampsia. 23rd Biennial International MLTD Congress, 14-17 Mayıs 2014, Valencia, Spain.
38. Ak, A., Ergun, I.S., Altinoz, H., Çıracı, E., Uyguner, O., Isbir, S., Arsan, S., Tetik, S.  GG Polymorphism of platelet glycoprotein IIB ITGA2B gene increases the magnitude of interleukin-6 release after cardiopulmonary bypass. Fourth International Meeting on Pharmacy and Pharmaceutical Sciences (IMPPS-4), 18-21 September 2014, Istanbul-Turkey  (PP248).
39. Sahin, S., Ozakpinar, O.B., Eroğlu, M., Tulunay, A., Ciraci, E., Uras, F., Tetik, S. The impact of platelet functions and inflammatory status on the severity of preeclampsia. Fourth International Meeting on Pharmacy and Pharmaceutical Sciences (IMPPS-4), 18-21 September 2014, Istanbul-Turkey  (PP247).
40. Sahin, S., Ozakpinar, O.B., Ak, Koray., Eroglu, M., Acikel M., Tetik, S., Uras, F., Cetinel, S. The protective effects of Tacrolimus on rat uteri exposed to ischemia-reperfusion injury: A biochemical and histopathologic evaluation. X. Turkish German Gynecology Congress. 30 April-4 May, 2014. Antalya-Turkey. =-06. ID:0349
41. Sahin, S., Ozakpinar, O.B., Eroglu, M., Tulunay, A., Ciraci, E., Uras, F., Tetik, S. Maternal Serum Levels of Cytokines are associated with the severity of preeclampsia. The 18th World Congress on Controversies in Obstetrics. Gynecology &Infertility (COGI). Wienna, Austria, October 24-27 2013.
42. Sahin, S., Ozakpinar, O.B., Ak, K., Eroglu, M., Açıkel MA, Tetik, S., Uras, F., Çetinel S. Tacrolimus ameliorates oxidative damage and protects from uterine ischemia-reperfusion injury in rats. The 18th World Congress on Controversies in Obstetrics. Gynecology &Infertility (COGI). Wienna, Austria, October 24-27 2013.
43. Sahin, S., Ozakpinar, O.B.,  Tulunay, A., Eroglu M,. Ciraci, E., Uras, F., Tetik, S. Alterations in platelet functions in the pre-eclamptic patients. Society of gynecologic investigation. Summit Turkey 2013.  Innovation in Obstetics and Gynecology September 5-8, 2013.
44. Altinoz, H., Ergun, I.S., Ak, K., Uyguner, Z.O., Yardimci, K.T. Tetik, S.  Evaluation of platelet GpIIb rs5911 polymorphism in relation to inflammation in patients with chronic obstructive pulmonary disease. AACC Annual Meeting&Clinical Lab Expo 2013 July-28-Agust 1 Houston-US.
45. Ergun, I.S., Altinoz, H., Uyguner, Z.O., Erdogan, N., Yardimci, K.T., Tetik, S.  The relationship platlet glycoprotein IIb rs 5911 polymorphism and prognostic parameters in female Turkish Patients with cancer. Trombosis Research Volume 130, Supplement 1, ISSN: 0049-3848 (International Congress on Thrombosis, 6-9 October, 2012, Nice-France)
46. Ersahin, M., Toklu, H., Erzik, C,. Akakin ,D,. Tetik, S., Sener, G., Yegen, B. The Antinflammatory Effects of Ghrelin on Experimental Spinal Cord Injury in Rats. 1th Middle East Neurosurgical Symposia. 8–11 April, 2010, Istanbul, Turkey (PP–24).
47. Tetik, S.  Evaluation of laboratory and test on Fibrinolytic System. 9th National Thrombosis, hemostasis and Anjiology Congress.  1Th Courses of Hemostasis. 6-8 March 2015 Florence Nightingale Hospital, Istanbul-Turkey.