Hosam Elbaz
Hosam Elbaz, PhD
Research adviser of Pharmaceutical Sciences

Egypt Scholars Inc.


  • Ph.D. in Pharmaceutical and Pharmacological Sciences, 2011, West Virginia University
  • Bachelor Degree (B.SC.) in Pharmaceutical Sciences, 2005, Misr International University, Heliopolis, Cairo, Egypt
  • Eligible to practice pharmacy in USA after license acquisition



Hosam Elbaz is a pharmacist and a pharmacologist. He graduated from Misr International University, college of pharmacy in June 2005. He then received his PhD from West Virginia University School of Pharmacy in December 2011, and then he finished a two-year postdoctoral fellowship at Wayne State University School of Medicine on March 2014. Dr. Elbaz is interested in experimental cancer therapeutics, particularly those derived from nutritional origins. He recently published a research article titled “Epicatechin Stimulates Mitochondrial Activity and Selectively Sensitizes Cancer Cells to Radiation” in which he showed that epicatechin, a natural ingredient of coffee and dark chocolate, can increase the sensitivity of cancer cells to conventional radiotherapy while non-cancerous tissues remain unharmed. He showed that increasing mitochondrial respiration in cancer cells renders them sensitive to cell death by radiation.


Research Interest

Cancer biology and therapeutics, Drug discovery, Preclinical drug development, Experimental pharmacology, Experimental toxicology, Applied pharmaceutical sciences, Cell signaling.


Professional Activities:

06/2014 – Present  Reviewer / Research adviser   Egypt Scholars Inc. Cairo Egypt
04/2014 – present Postdoctoral Research Department of Internal Medicine, Division of Gastroenterology, University of Michigan
02/2012 –03/2014 Postdoctoral Research Department of Radiation Oncology and Center for Molecular Medicine and Genetics Wayne State University
08/2007 – 12/2011 Doctoral Research Department of Basic Pharmaceutical Sciences West Virginia University
01/2010 – 12/2011 Faculty Biopharmaceutical Colloquium PHAR 783, Chemistry of Drug Action PHAR 71,1Pharmaceutical Care Lab 1 PHAR 70,1Pharmaceutics 1 PHAR 702 West Virginia University


Honors and Awards


  1. Alshaarawy, O., and Elbaz, H. (2015) Serum Cotinine levels and Diabetes Mellitus in Never Smokers. Journal of Diabetes and Its Complications. August, 24, DOI: http://dx.doi.org/10.1016/j.jdiacomp.2015.08.018 (In press).
  2. Shay, J., Elbaz, H., Lee, I., Zielske, S., Malek, M. and Hüttemann, M. (2014) Molecular mechanisms and therapeutic effects of (-)-epicatechin and other polyphenols in cancer, inflammation, diabetes, and neurodegeneration. Oxidative Medicine and Cellular Longevity. December, 31.DOI: http://dx.doi.org/10.1155/2015/181260
  3. Fasih, A.*, Elbaz, H.*, Hüttemann, M., Konski, A., Zielske, S. (2014, * these authors contributed equally) Radiosensitization of pancreatic cancer cells by metformin through the AMPK pathway. Radiation Research. June 7. DOI: http://dx.doi.org/10.1667/RR13568.1
  4. Eldawud, R., Stueckle, T.A., Manivannan, S., Elbaz, H., Rojanasakul, Y., and Dinu, C.Z. (2014) Real Time Analysis of the Effects of Toxic, Therapeutic and Subtherapeutic Concentrations of Digitoxin on Lung Cancer Cells. Biosensors and Bioelectronics. March 26. DOI: 10.1016/j.bios.2014.03.030
  5. Elbaz, H., Liu, J., Antwih, D., Lee, I., Hüttemann, M., Zielske, S. (2014) Epicatechin Stimulates Mitochondrial Activity and Selectively Sensitizes Cancer Cells to Radiation. PLoS One. February 6; 9(2):e88322. DOI: 10.1371/journal.pone.0088322.
  6. Elbaz, H., Stueckle, T., Rojanasakul, Y., Dinu, C.Z., (2012) Digitoxin and its analogs as novel cancer therapeutics. Experimental Hematology and Oncology. April 5; 1. DOI: 10.1186/2162-3619-1-4
  7. Elbaz, H., Stueckle, T., Wang, H., O’Doherty, G., Lowery, D., Sargent, L., Wang, L., Dinu, C.Z., Rojanasakul, Y. (2012) Digitoxin and Synthetic Analog Inhibit Cell Viability in Lung Cancer Cells. Toxicology and Applied Pharmacology. January 1; 258(1): 51-60. DOI: 10.1016/j.taap.2011.10.007.
  8. Iyer, A., Zhou, M., Azad, N., Elbaz, H., Wang, L., Rogalsky, K., Rojanasakul, Y., O'Doherty, G. & Langenhan, J. (2010). A Direct Comparison of the Anti cancer Activities of Digitoxin MeON-Neoglycosides and O-Glycosides. ACS Medicinal Chemistry. Jul 12; 1(7):326-330. PMCID: PMC2916185.

Book chapter

  • Huttemann, M; Doan, JW; Goustin, AS; Sinkler, C; Mahapatra, G; Shay, J; Liu, J; Elbaz, H; Aras, S; Grossman, LI; Ding, Y; Zielske, SP; Malek, MH; Sanderson, TH; Lee, I. (2014). Regulation of cytochrome c in respiration, apoptosis, neurodegeneration and cancer – the good, the bad and the ugly. In: Cytochromes b and c: Biochemical Properties, Biological Functions and Electrochemical Analysis. Nova Science Publishers, New York. IN PRESS


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