Education

• Ph. D. Degree, Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, University of Marmara, 2006.
• M. Sc. Degree, Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Marmara, 1996
• B. Pharm. Degree, Faculty of Pharmacy, University of Istanbul, 1992

Profile

Associate Prof. Ali Demir SEZER, after completing his bachelor’s degree from University of Istanbul, Faculty of Pharmacy, Associate Prof. Ali Demir SEZER began working as a research assistant at the Department of Pharmaceutical Technology of the Marmara University, Faculty of Pharmacy in 1993, and completed his masters degree in new generation controlled release systems, which was followed by the completion of his PhD in Pharmaceutical Biotechnology at the same department. Dr. Sezer, who was appointed as a Lecturer briefly after, and carried out his research at the same branch, became associate professor in 2013. Dr. Sezer’s areas of expertise are protein formulation, nanobiotechnology, pharmaceutical biotechnology and production methodologies, and the use of the new generation of drug delivery systems and biopolymers in pharmaceutical industry. Dr. Sezer has numerous publications in the journals in international indexes, international book editions, chapter authorships, and patents. Moreover, Dr. Sezer actively took part in and mentored a variety of corporate and other institutional projects, particularly Scientific and Technological Research Council of Turkey (TÜBİTAK). He is also a peer reviewer and member of the editorial boards in international journals, and has papers at international congresses.

Research Interest

Nanobiotechnology, nano and microcarrier systems, drug delivery and formulations dizyn, modern therapeutic systems, biopolymers, wound healing, recombinant DNA technology, antisense technology.

Professional Activities:

• Associate Professor - Faculty of Pharmacy, Department of Pharmaceutical Technology and Biotechnology, Marmara University, Turkey
• Membership in Societies: International Microencapsulation Society, Chitin and Chitosan Society, European Society of Biotechnology, Association Pharmaceutical Sciences of Ankara (FABAD), Turkish Pharmacetical Technology Scientists Association (TÜFTAD)

Honors and Awards

Publications

Research Papers

1. A.D. Sezer, J. Akbuğa, Controlled release of piroxicam from chitosan beads, International Journal of Pharmaceutics, 121 (1995) 113-116.
2. A.D. Sezer, J. Akbuğa, Release characteristics of chitosan treated alginate beads I: Sustained release of a macromolecular drug from chitosan treated alginate beads, Journal of Microencapsulation, 16 (1999) 195-203.
3. A.D. Sezer, J. Akbuğa, Release characteristics of chitosan treated alginate beads II: Sustained release of low molecular drug from chitosan treated alginate beads, Journal of Microencapsulation, 16 (1999) 687-696.
4. A.D. Sezer, A. L. Baş, J. Akbuğa, Encapsulation of enrofloxacin in liposomes I: Preparation and in vitro characterization of LUV, Journal of Liposome Research, 14 (2004) 77-86.
5. A.D. Sezer, J. Akbuğa, Fucosphere – new microsphere carriers for peptide and protein delivery: preparation and in vitro characterization, Journal of Microencapsulation, 23 (2006) 513-522.
6. A.D. Sezer, J. Akbuğa, A. L. Baş, In vitro evaluation of enrofloxacin – loaded MLV liposomes, Drug Delivery, 14 (2007) 47-53.
7. A.D. Sezer, F. Hatipoğlu, E. Cevher, Z. Oğurtan, A. L. Baş, J. Akbuğa, Chitosan films containing fucoidan as a wound dressing for dermal burn healing: Preparation and in vitro/in vivo evaluation, AAPS PharmSciTech, 8:2 (2007) Article 39, E1-E8.
8. F. Hatipoğlu, Z. Oğurtan, A. D. Sezer, K. Üney, M. Erol, Ö. Özdemir, A. L. Baş, J. Akbuğa, Effect of laminarin and chitosan gel formulations on the treatment of hydrofluoric acid induced corneal burns in the rabbits, Revue de Médecine Vétérinaire, 159:4 (2008) 203-210.
9. A.D. Sezer, E. Cevher, F. Hatipoğlu, Z. Oğurtan, A. L. Baş, J. Akbuğa, The use of fucosphere in the treatment of dermal burns in rabbits, European Journal of Pharmaceutics and Biopharmaceutics , 69:1 (2008) 189-198.
10. A.D. Sezer, E. Cevher, F. Hatipoğlu, Z. Oğurtan, A. L. Baş, J. Akbuğa, Preparation  of fucoidan-chitosan hydrogel and its application as burn healing accelerator on rabbit, Biological and Pharmaceutical Bulletin, 31:12 (2008) 2326-2333.
11. A.D. Sezer, J. Akbuğa, Comparison on in vitro characterization of fucospheres and chitosan microspheres encapsulated plasmid-DNA (pGM-CSF): Formulation design and release characteristics, AAPS PharmSciTech, 10:4 (2009) 1193-1199.
12. S.Özbaş-Turan, J. Akbuğa, A. D. Sezer, Topical Application of Antisense Oligonucleotide Loaded Chitosan Nanoparticles to Rats, Oligonucleotides, 20:3 (2010) 147-153.
13. A.D. Sezer, H. Kazak, E. T. Öner, J. Akbuğa, Levan-based nanocarrier system for peptide and protein drug delivery: Optimization and influence of experimental parameters on the nanoparticle characteristics, Carbohydrate Polymers, 84:1 (2011) 358-363. 
14. A.D. Sezer, J. Akbuğa, The design of biodegradable core-shell microspheres contaning ofloxacin: influence of the formulation parameters on in vitro characterization, Drug Development and Technology, 17:1 (2012) 118-124.
15. A.L. Baş, K. Üney, H. H. Hadimli, A. D. Sezer, F. Hatipoğlu, M. Maden, J. Akbuğa, Cytologic-enzymologic diagnosis of experimental pneumonia formed with Klebsiella pneumoniae serotype II in rats and its treatment with liposomal enrofloxacin, Kafkas Universitesi Veteriner Fakultesi Dergisi, 19:2 (2013) 183-190.

Review

1. A.D. Sezer, F. Yağcı. ‘Overview of peptide and protein PEGylation: properties and general strategies’ Acta Pharmaceutica Sciencia 52 (2010) 376-388.
2. A.D.Sezer, E. Cevher. ‘Topical drug delivery using chitosan nano- and microparticles’     Expert Opinion on Drug Delivery, 9:9 (2012) 1129-1146.

Book Chapters

1. A.D. Sezer. Chitosan: properties and its pharmaceutical and biomedical aspects. In: Samuel P. Davis, editor. Focus on chitosan research. pp. 377-398, Hauppauge, NY, USA: Nova Publisher; 2011 (ISBN: 978-1-61324-454-8).
2. A.D. Sezer, E. Cevher. Fucoidan: a versatile biopolymer for biomedical applications. In: Meital Zilberman, editor. Biomaterials and nanostructures for active implants. pp. 377-406, Heidelberg, Berlin, Germany, Springer-Verlag Publisher, 2011 (ISBN: 978-3-642-18064-4).
3. A.D. Sezer, E. Cevher. Biopolymers as wound healing materials: Challenges and new strategies. In: Rosario Pignatello, editor, Biomaterial / Book 3. pp. 383-414, Rijeka, Croatia, In Tech Open Acesss Publisher, 2011 (ISBN 979-953-307-295-0).
4. E. Cevher, A. D. Sezer, E.Ş. Çaglar. Gene delivery systems: Recent progress in viral and non-viral therapy. In: Ali Demir Sezer, editor, Recent advances in novel drug carrier systems. pp. 437-470, Rijeka, Croatia, InTech Open Acesss Publisher, 2012 (ISBN 978-953-51-0810-8).
5. S. Bucak, B. Yavuztürk, A. D. Sezer. Magnetic nanoparticles: Synthesis, surface modifications and application in drug delivery. In: Ali Demir Sezer, editor, Recent advances in novel drug carrier systems. pp. 165-200, Rijeka, Croatia, InTech Open Acesss Publisher, 2012 (ISBN 978-953-51-0810-8).
6. M. Çağdaş, A.D. Sezer, S. Bucak. Liposomes as potential drug carrier systems for drug delivery application of nanotechnology in Drug Delivery. In: Ali Demir Sezer, editör, Application of nanotechnology in drug delivery. pp.1-50, Rijeka, Croatia, InTech Open Acesss Publisher ISBN 978-953-51-1628-8.
7. K. Elçioğlu, A.D. Sezer. Nanoparticle insulin drug delivery — Applications and new aspects. In: Ali Demir Sezer, editör, Application of nanotechnology in drug delivery. pp.237-257, Rijeka, Croatia, InTech Open Acesss Publisher ISBN 978-953-51-1628-8.

Book Editor

1. Recent advances in novel drug carrier systems, Edited by Ali Demir Sezer, ISBN 978-953-51-0810-8, Publisher: InTech, Open Acesss Publisher, Published: October 31, 2012 under CC BY 3.0 license, insubject Pharmaceutical Science.
2. Application of nanotechnology in drug delivery, Edited by Ali Demir Sezer, ISBN 978-953-51-1628-8, Publisher: InTech, Open Acesss Publisher, Published: July 25, 2014 under CC BY 3.0 license, insubject Pharmaceutical Science.