Associate Professor of Neurology
University of Colorado Denver
USA
Education
1973-1983 | School #5, Khabarovsk, Russia, graduated with Gold Medal, GPA 5.00 of 5.00 |
1983-1989 | Far Eastern State Medical University (Khabarovsk State Medical Institute), Khabarovsk, Russia, GPA 5.00 of 5.00, graduated with Honors, |
1989-1996 | Neurology Residency, Far Eastern State Medical University, Khabarovsk, Russia |
1996 | Neurophysiology Fellowship, Far Eastern State Medical University, Khabarovsk |
2001-2002 | Internal Medicine Internship, Resurrection Medical Center, Westlake Hospital Melrose Park, Illinois |
2002-2005 | Neurology Residency, University of Colorado Denver, Aurora, Colorado |
2005-2006 | Movement Disorders Fellowship, Stanford University Medical Center, Stanford, California |
Profile
Olga S. Klepitskaya, M.D. is a board-certified and fellowship-trained movement disorders neurologist with expertise in Deep Brain Stimulation(DBS). She is an Associate Professor of Neurology and a co-director of the University of Colorado DBS program, one of the busiest and most experienced in the nation. She sees patients at the University of Colorado Hospital and the Veterans Administration Hospital in Denver. She has delivered multiple research presentations about DBS at national and international meetings. She is actively participating in clinical trials of new pharmacological and surgical treatments of movement disorders, and has been the Primary Investigator on more than a dozen studies.
Research Interest
Dr. Klepitskaya’s research interests include the outcomes of Deep Brain Stimulation, specifically the long-term effect of DBS on the progression of Parkinson’s Disease (PD) and changes in non-motor symptoms after DBS. She is also interested in the neurophysiological aspects of PD studied by intra-operative recording during DBS surgeries.
Professional Activities:
Academic Appointments:
1990-1992 | Instructor in Neurology, Department of Speech Disorders and Therapy, Far Eastern State Pedagogical University, Khabarovsk, Russia |
1990-1992 | Instructor in Neurology, Department of Neurology, Far Eastern State Medical University, Khabarovsk, Russia |
1994-1998 | Instructor in Neurophysiology, Department of Continued Medical Education, Far Eastern State Medical University, Khabarovsk, Russia |
2006-2008 | Clinical Instructor, Department of Neurology, University of Colorado Denver, Aurora, CO |
2008-2014 | Assistant Professor, Department of Neurology, University of Colorado Denver, Aurora, CO |
2008-present | Co- Director, Deep Brain Stimulation Center, University of Colorado Hospital, Aurora, CO |
2014-present | Associate Professor Department of Neurology, University of Colorado Denver, Aurora, CO |
Hospital, government or other professional positions:
1989-1990 | Research Associate, Central Research Laboratory, Far Eastern State Medical University, Khabarovsk, Russia |
1989-1996 | Teaching Assistant, Department of Neurology, Far Eastern State Medical University, Khabarovsk, Russia |
1992-1994 | Director of Public Relations Department, Far Eastern Association of Medical Workers, Khabarovsk, Russia |
1992-1994 | Medical Journalist and Editor, Far Eastern TV/Radio Station, Khabarovsk, Russia |
1994-1998 | Attending Neurologist, Department of Neurology, Regional Hospital #1, Khabarovsk, Russia |
1996-1998 | Director, Electroencephalography Laboratory, Department of Neurodiagnositcs, Regional Hospital #1, Khabarovsk, Russia |
1996-1998 | Neurophysiologist, Department of Neurodiagnostics, Regional Hospital #1, Khabarovsk, Russia |
1998-1999 | Research Assistant, Department of Neuroscience, Sleep Laboratory, Washington State University, Pullman, Washington |
1999-2001 | Medical and Social Interpreter, Social and Health Services, State of Washington, Spokane, Washington |
2000 | Medical Consultant, Ukrainian-American Educational Project, Washington State University, Pullman, Washington |
2000-2001 | Electroencephalography Technician, Gritman Medical Center, Moscow, Idaho |
2006-present | Attending Neurologist, University of Colorado Hospital, Aurora, Colorado |
2007-2008 | Attending Neurologist, The Children’s Hospital, Aurora, Colorado |
2007-present | Staff Neurologist, Veterans AdministrationHospital, Denver, Colorado |
Professional Organizations and Affiliations:
1999-indefinite | Russian Association of Neurologists and Neurosurgeons |
2003-present | American Academy of Neurology (AAN) |
2006-present | Movement Disorders Society (MDS) |
2006-2007 | International Society of History of Neurology |
2006-present | Parkinson Association of the Rockies (PAR) |
2007-present | Parkinson Study Group (PSG) – membership by credentialing |
2006-present | Colorado Society of Clinical Neurology |
2013-present | American Neurological Association (ANA) |
Honors and Awards
Publications
Peer-reviewed Articles:
- Klepitskaya OS,Shishmakov, YV. Biological Activity of Pine-Tree Oil.Questions of the Ecological Biochemistry and Physiology;1988: 45-49 Article in Russian
- Klepitskaya OS,Ottieva, EN. Neurological Disorders in Patients with Lupus Erythematosus.Far Eastern Medical Journal;1998(2):67-68 Article in Russian
- Klepitskaya OS, Rykova MG. Modern Clinical Variations of Conversion Disorder.Topics in Psychopathology. Publication of the Russian Institute of Mental Diseases named after Serbskiy; 1998:22-28Article in Russian
- Goetz CG, Tilley BC, Shaftman SR, Stebbins GT, Fahn S, Martinez-Martin P, Poewe W, Sampaio C, Stern MB, Dodel R, Dubois B, Holloway R, Klepitskaya O,Jankovic J, Kulisevsky J, Lang AE, Lees A, Leurgans S, LeWitt PA, Nyenhuis D, Olanow CW, Rascol O, Schrag A, Teresi JA, van Hilten JJ, LaPelle N; Movement Disorder Society UPDRS Revision Task Force. Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results. Movement Disorders. 2008; 23 (15): 2129 - 2170
- Kluger BM, Klepitskaya O, Okun MS. Surgical Treatment of Movement Disorders. Neurologic Clinics of North America;2009:633-677
- Patel SG, Stickrath CR, Anderson M, Klepitskaya O. How Should Parkinson’s Disease be Managed Perioperatively? The Hospitalist. 2010;15(6):19-22 http://www.thehospitalist.org/details/article/704937/How_should_Parkinsons_disease_be_managed_perioperatively.html
- Spielman J, Mahler L, Halpern, A, Gilley P, Klepitskaya O, Ramig L. Intensive Voice Treatment (LSVT®LOUD) for Parkinson's disease following Deep Brain Stimulation of the Subthalamic Nucleus. Journal of Communication Disorders. 2011;doi:10.1016/j.jcomdis.2010.05.003
- Klepitskaya OS, Cole W, Henderson J, Bronte-Stewart H. Deep Brain Stimulation in “On”- Parkinson Hyperpyrexia. Neurology. 2011;76(7): s69-s71
- Hall D, Klepitskaya O, Leehey M. Fragile X-Associated Tremor Ataxia Syndrome in FMR1 Gray Zone Allele Carriers.Movement Disorders. 2011;27(2):297-301
- Klepitskaya O, Neuwelt AJ, Nguyen T, Leehey M. Primary dystonia misinterpreted as Parkinson disease: Video case presentation and practical clues. Neurology: Clinical Practice. 2013; 3(6), 469-474.
Book Chapters:
- Klepitskaya O. Parkinsonism- Hyperpyrexia syndrome.In: Kompoliti K, and Verhagen Metman L (eds.) Encyclopedia of Movement disorders. 2010; vol. 1, pp. 399-401 Oxford: Academic Press.
- Klepitskaya O. Dopamine Dysregulation syndrome. In: Kompoliti K, and Verhagen Metman L. (eds.) Encyclopedia of Movement disorders. 2010; vol. 1, pp. 323-326 Oxford: Academic Press.
- Berk J,Klepitskaya O. Thalamotomy. In: Mechanisms and emerging therapies of tremor disorders. New York: Springer; 2013(24):431-461
- Klepitskaya O. Restless Leg Syndrome. In: Barton B and Hall D (eds.)Non-Parkinsonian Movement Disorders. 2013; Oxford: Wiley-Blackwell (in print)
Scientific Abstracts and Poster Presentations(competitive):
- Klepitskaya OS, Maa EH, Tyler KL. Delayed Seroconversion in Immunocompromised Patient with West Nile Virus-Associated Brainstem Encephalitis. 57th Annual Meeting of the American Academy of Neurology, April 2005, Miami, Fl, USA
- Klepitskaya OS, Proskokova TN.Hepatolenticular Degeneration: Wilson- Konovalov’s Disease. 58th Annual Meeting of the American Academy of Neurology, April 2006, San Diego, CA, USA Neurology;2006(66):A2
- Grenier Y, Spielman JL, Klepitskaya OS, Ramig LO, Henderson JM, Bronte-Stewart HM.Methodology for objective motor speech assessment outcome after deep brain stimulation for Parkinson’s disease. 10thInternational Movement Disorders Congress, Kyoto, Japan, October 2006 Movement Disorders;2006(21):S655
- Klepitskaya OS, Cole WL, Bronte-Stewart HMEvolution of Parkinson disease during 4 years of Deep Brain Stimulation: a case report. 10th International Movement Disorders Congress, Kyoto, Japan, October, 2006 Movement Disorders;2006(21):S665
- Klepitskaya OS, Fischbein NJ, Hall DA, Bronte-Stewart HM. Superficial Siderosis with supranuclear palsy, parkinsonism and falls. 10th International Movement Disorders Congress, Kyoto, Japan, October, 2006Movement Disorders;2006(21):S525- S526
- Klepitskaya OS, Cole WL, Henderson JM, Bronte-Stewart HM. Deep brain stimulation decreases the risks for Parkinsonism-Hyperpyrexia syndrome and suppresses levodopa-induced dyskinesias: a case report.10th International Movement Disorders Congress, Kyoto, Japan, October, 2006.Movement Disorders;2006(21):S666-S667 and Annual meeting of Parkinson Study Group, Chicago IL, USA, 2006 Movement Disorders;2006(21):1552
- Richardson MS, Ojemann SG, Klepitskaya OS. Response of the subthalamic nulcleus neurons to vocalization.11th International Movement Disorders Congress, Istanbul, Turkey, June 2007.Movement Disorders;2007(22):S53 and 1st international symposium “Basal ganglia speech disorders and Deep Brain Stimulation,” July 2007, London, UK
- Klepitskaya OS, Kim Z, Richardson MD, Ojemann SG. Three-dimensional computerized model of subthalamic nucleus. 12th International Movement Disorders Congress, Chicago, IL, USA, June 2008.Movement Disorders;2008(23):S108 – Poster was selected for guided poster tour
- Klepitskaya O, Kumar R. Efficacy and Safety of Low Level Electromagnetic Fields Treatment in Parkinson’s Disease. Annual meeting of Parkinson’s Study Group, Salt Lake City, UT, USA. Movement Disorders;2008(11):1633
- Klepitskaya OS, Fowler JJ, Kluger BM, Ojemann SG. Number of microelectrode recording passes during bilateral staged vs. unstaged deep-brain stimulation surgery for Parkinson's disease. 13th International Movement Disorders Congress, Paris, France, June 2009. Movement Disorders;2009(24):S485-S486
- Klepitskaya OS, Koop MM, Bronte-Stewart HM. Longitudinal study of Microlesion Effect on Bradykinesia after Subthalamic Nucleus Deep Brain Stimulation Surgery for Parkinson's disease. 13th International Movement Disorders Congress, Paris, France, June 2009 Movement Disorders;2009(24):S485
- Reid KA, Hoyt B, Tanabe J, Ojemann SG, Legenska A, Klepitskaya OS. Prevalence of dopamine dysregulation syndrome in Parkinson’s disease patients-candidates for deep brain stimulation. 14th International Movement Disorders Congress, Buenos Aires, Argentina, June 2010 Movement Disorders;2010(25):S282
- Klepitskaya OS, Hoyt B, Berk JJ, Ojemann SG. Reversible cognitive impairment induced by deep brain stimulation of subthalamic nucleus. 14th International Movement Disorders Congress, Buenos Aires, Argentina, June 2010 Movement Disorders;2010(25):S446
- Pelak VS, Choi M, Jung S, Halliday B, Hager E, Klepitskaya O, Ojemann S, Filley C, Dubin M. “Visuospatial Assessment By Virtual 3D Radial Optic Flow Illusion In Healthy Aging, Mild Alzheimer’s Disease (AD), And Pre-Deep-Brain Stimulation (DBS) Parkinson’s Disease (PD) Subjects.” Abstract A-316-0002-01523. 10th Annual International Conference on Alzheimer’s and Parkinson’s Disease. Barcelona, Spain. March 9-13th, 2011
- Hall D, Klepitskaya OS, Tassone F, Spector E, Leehey M. FXTAS in Patients with Fragile X Gray Zone Alleles. 63rd Annual AAN Meeting, Honolulu, Hawaii, March 2011. Neurology; 2011(76)9:SA399
- O.S. Klepitskaya, Z. Kim, S.G. Ojemann. Mock microelectrode recording is undistinguishable from a real time recording in sham surgery controlled clinical trial of new surgical treatment for Parkinson’s disease [Abstract 221]. International Movement Disorders Congress. Toronto, Canada, June 2011.Movement Disorders; 2011;26(Suppl 2): page S73
- Ragole T, Michas-Martin A, Moss A, Juarez-Colunga E, Klepitskaya O. “Review of published outcomes of subthalamic nucleus deep brain stimulation in Parkinson disease supports hypothesis of disease-modifying effect.”2013 International Movement Disorders Congress. Sydney, Australia, June 2013.Movement Disorders; 2013(25):1316, 25th Annual meeting of Parkinson’s Study Group & 27th Annual PSG Symposium, Montreal, Canada.