Education

Biography

Dr. David A. Stout is an assistant professor with a joint appointment in the Department of Mechanical and Aerospace Engineering and in the Department of Biomedical Engineering at California State University, Long Beach. He received his B.Sc. degree in Aerospace Engineering with a minor in Chemistry from California State University, Long Beach in 2010, and a Ph.D. from Brown University in Biomedical Engineering in 2014. While at Brown, Dr. Stout was a member of the Nanomedicine Laboratories focusing on the development of cardiovascular nano-biomaterials and the developed a system to investigate the migration forces of human neutrophils in a 3D environment to better understand cell mechanics and cancer migration.

Currently, Dr. Stout is the founding director of the Long Beach Bioengineering Laboratory at California State University, Long Beach, a BSL-2 facility, where he oversees all research projects—ranging from nano-cardivascular research to contraceptive design to 3D tissue printing.

Dr. Stout's main research focus is applying engineering techniques to the biomedical world to combat some of the most deadly diseases and infections. His research expertise is in cardiovascular biomaterials, orthopedic biomaterials, nano-medicine, solid mechanics, cell mechanics and migration.

Dr. Stout is a recipient of numerous awards ranging from The National Science Foundation (NSF) Graduate Student Fellowship to the (twice) Indo-US Science and Technology Forum (IUSSTF) Research Fellowship. He is a member of BMES, Tau Beta Pi, SigmaXi, and SFB.

Research Interest

Professional Activities:

Awards, Honors and Membership in Honorary Societies:

Publications

Research Publications, Peer Reviewed:

1. Yang, Y., V. Chinthapenta, Q. Li, D.A. Stout, A. Liang, B. Sheldon, and T.J. Webster."Understanding Osteoblast Responses on Stiff Nanotopographies through Experiments and Computational Simulation." Journal of Biomedical Materials Research Part A. 97A, 2011.
2. Stout, D.A., B. Basu, and T.J. Webster. "Poly Lactic-Co-Glycolic Acid: Carbon Nanofiber Composites for Myocardial Tissue Engineering Applications." Acta Biomaterialia, 7(1): 3101-3112, 2011.
3. Stout, D.A., and T.J. Webster. "Novel Nano Drug Systems for Cardiovascular Applications."Recent Patents on Biomedical Engineering, 5(1): 3-13, 2012.
4. Stout, D.A., and T.J. Webster. "Carbon Nanotubes for Stem Cell Control." Materials Today, 15(7-8): 312-318, 2012.
5. Meng X., D.A. Stout, L. Sun, H. Fenniri, and T.J. Webster. "Novel injectable biomimetic hydrogels with carbon nanofibers and self-assembled rosette nanotubes for myocardial applications."Journal of Biomedical Materials Research Part A, 101(4):1095-102, 2012.
6. Stout, D.A., J. Yoo, A.N. Santiago-Miranda, and T.J. Webster. "Mechanisms of Greater Cardiomyocyte Functions on Conductive Nanoengineered Composites for Cardiovascular Applications."International Journal of Nanomedicine, 7(1): 5653-5669, 2012.
7. Stout, D.A., and T.J. Webster. "The Effect of Carbon Nanofiber Density in Poly(lactic-co-glycolic acid) Composites for Myocardial Tissue Engineering Applications."Nano Bulletin, 1(1): 120102-1:120102-6, 2012.
8. Sun L., D.A. Stout, and T.J. Webster. "The Nano-Effect: Improving the Long-Term Prognosis for Musculoskeletal Implants."Journal of Long Term Effects of Medical Implants, 22(3): 195-209, 2012.
9. Aninwene II G.E., D.A. Stout, Z. Yan, and T.J. Webster. "Nano-BaSO4: A Novel Antimicrobial Additive to Pellethane."International Journal of Nanomedicine, 8(1): 1197-1205, 2013.
10. Webster, T.J., D.A. Stout, S. Kalmodia, and B. Basu. "Experimental Methods and In Vitro Cytoxicity and Genotoxicity of Nanomaterials."Nano LIFE, 3(3): 1340-1361, 2013.
11. Stout, D.A., E. Raimondo, G. Marostica, and T.J. Webster. "Growth characteristics of different heart cells on novel nanopatch substrate during electrical stimulation."Bio-Medical Materials and Engineering, 3(3): 1340-1361, 2013.
12. Stout, D.A., "Recent Advancements in Carbon Nanofiber and Carbon Nanotube Applications in Drug Delivery and Tissue Engineering." Current Pharmaceutical Design, 21(15): 20372044, 2015. (PMID:25732658)
13. Stout, D.A., J. Toyjanova, and C. Franck. "Planar Gradient Diffusion System to Investigate Chemotaxis in a 3D Collagen Matrix." Journal of Visualized Experiments (JoVE), Jun 12;(100): e52948, 2015. (PMID:26131645)
14. Stout, D.A., E. Bar-Kochba, J.B. Estrada, J. Toyjanova, H. Kesari, J.S. Reichner, and C. Franck. “Mean deformation metrics for quantifying 3D cell-matrix interactions without requiring information about material properties." Proceedings of the National Academy of Sciences (2016): (201510935).
15. Gagan, J., C. Fraze, and D.A. Stout. "Three-Dimensional Stem Cell Bioprinting." Cell Stem cells and Regenerative Medicine, 2(2): 2016. doi: http://dx.doi.org/10.16966/csrm.110
16. Amezcua R., A. Shirolkar, C. Fraze, and D.A. Stout. "Nanomaterials for Cardiac Myocyte Tissue Engineering." Nanomaterials, 6(133): 2016. dio:10.3390/nano6070133

Recent Refereed Proceeding Publications

1. Stout, D.A., and H.H. Chen. "Hawksat-1: Introducing 'COTS' CubeSat Satellite System Variable."Proceedings of the National Conference on Undergraduate Research. Asheville: University of North Carolina at Asheville, 9(1): 246-253, 2009.
2. Yang, L., D.A. Stout, A. Liang, and T.J. Webster. "The Impact of Substrate Topography on Cell Filopodia Extension and Cell Spreading." in Business and Safety Issues in the Commercialization of Nanotechnology, edited by S.S. Mao, L. Merhari, J. van Schijndel, L. Tsakalakos, R. Hurt, H. Liu, T.J. Webster. Mater. Res. Soc. Symp. Proc., Volume 1209, Paper #1209-YY02-03, 2010.
3. Stout, D.A., J. Yoo, and T.J. Webster. "Poly Lactic-Co-Glycolic Acid Carbon Nanofiber Composite for Enhancing Cardiomyocyte Function." in Nanofunctional Materials, Nanostructures, and Nanodevices for Biomedical Applications II, Mater. Res. Soc. Symp Proc.,Volume 1316, Paper #913663-QQ06-33, 2011.
4. Stout, D.A., B. Basu, and T.J. Webster. "Cytocompatible Poly-Lactic-co-Glycolic Acid: Carbon Nanofiber Composite Analysis for Cardiovascular Applications." Northeast Bioengineering Conference, IEEE 2011, 978-1-61284-826-6, 2011.
5. Stout, D.A., J. Yoo, and T.J. Webster. "Conductivity and Cardiomyocyte compatibility of Poly Lactic-co-Glycolic Acid Carbon Nanofiber Composites." 8th International Conference on Composite Materials Proceedings, Paper #F-26, 2011.
6. Stout, D.A., E. Raimondo, and T.J. Webster. "Improved Cardiomyocyte Functions of Carbon Nanofiber Cardiac Patches," in Biomaterials for Tissue Regeneration, Mater. Res. Soc. SympProc., Volume 1417E, Paper #KK036, 2012.
7. Meng, X., D.A. Stout, L. Sun, H. Fenniri, and T.J. Webster. "Injectable Composites with Carbon Nanofibers and Helical Rosette Nanotubes for Myocardial Tissue Engineering." in Biomaterials for Tissue Regeneration, Mater. Res. Soc. Symp Proc., Volume 1417E, Paper #KK03.22, 2012.
8. L. Weng, D.A. Stout, and T.J. Webster. "Nanophased Magnesium for Orthopedic Applications."Northeast Bioengineering Conference, IEEE 2012, 2012.

Recent Book Chapters

1. Meng, X., Stout, D.A., Sun, L., Fenniri, H. and Webster, T. "Injectable Biomimetic Hydrogels with Carbon Nanofibers and Novel Self Assembled Chemistries for Myocardial Applications." in Biomaterials Science: Processing, Properties and Applications II: Ceramic Transactions, Volume 237, ed by R. Narayan, S. Bose and A. Bandyopadhyay, (Hoboken, NJ): John Wiley & Sons, Inc., 2012.
2. Taylor, E., D.A. Stout, G. Aninwene II, and T.J. Webster. "In Vivo assessment of Nanotechnology in Biomaterials." in Nanomedicine: Principles and Perspectives, Volume 1 & 2 ed Yi Ge (New York, NY): Springer, 2013.
3. Stout, D.A., N.G. Drumus, and T.J. Webster. "Synthesis of Carbon based Nanomaterials for Tissue Engineering." in Nanomaterials in Tissue Engineering: Characterization, Fabrication and Applications ed by Gaharwar, Sant, Hancock, and Hancking (Cambridge, UK): Woodhead, 2013.