Ana Filipa Marques De Brito
Ana Filipa Marques De Brito
Researcher

University of Coimbra
Portugal

Education

2015

 

PhD

Health Sciences, field of Biomedical Sciences
Faculty of Medicine, University of Coimbra

2008

 

 MSc

 

 Biomedical Engineering
Faculty of Sciences and Technology, University of Coimbra

Biography

Ana Brito has completed the MSc in Biomedical Engineering, in the Faculty of Sciences and Technology, University of Coimbra, in September 2008. She performed a professional traineeship at Associação de Apoio ao Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (ACIMAGO). In addition, she has collaborated as Researcher and Research technician at Biophysics Unit of Faculty of Medicine, University of Coimbra. She was awarded with an individual PhD scholarship from the Portuguese Foundation for Science and Technology and developed its PhD project at Biophysics Unit / IBILI, Faculty of Medicine, University of Coimbra. Since April 2014 she is collaborator of Reg4life being responsible for regulatory affairs. In February 2015 completed a PhD in Health Sciences, field of Biomedical Sciences, in the Faculty of Medicine, University of Coimbra. It is co-author of 15 scientific papers, 1 book chapter and 160 abstracts in scientific conference proceedings.

Position and employment:

2007-2008 Centre of Ophthalmology and Vision Sciences / IBILI, Faculty of Medicine Internship / Masters StudentUniversity of Coimbra
 2008 to 2009 Biophysics Unit of the Faculty of Medicine Research technician (volunteer)University of Coimbra
   2009 to 2010   ACIMAGO Professional Internship University ofCoimbra
   2010 to 2014 Biophysics Unit of the Faculty of Medicine PhD student (Scholarship)University of Coimbra, Portugal
  2014 to present Reg4Life –Regeneration Technology, S. A., Regulatory affairs and ResearcherCantanhede, Portugal

 

Research Interest

 

Professional Activities:

Member Of Scientific Associations

European Association for the study of the Liver (EASL)from 2014
Portuguese Association for Cancer Research (ASPIC) from 2013
European Association for Cancer Research (EACR)  from 2011

Honors And Awards

  1. Best oral communication in the XXV National Congress of Portuguese Society of Surgery - 2015
  2. Honorable mention at the 18th Annual Meeting of the Portuguese Association for the study of the liver  -2015
  3. Best oral presentation at 2nd Luso-Brazilian Congress of Oncology -2015
  4. Poster of Excellence, United European Gastroenterology Week- 2014
  5. Travel Grant, United European Gastroenterology Week- 2014
  6. Young Investigator Bursary at European Association for the Study of the  Liver HCC Summit (Basic Science): Molecular Pathogenesis and Translational Research in Liver Cancer-2014
  7. Best oral presentation at the 16th Annual Meeting of the Portuguese Association for the study of the liver-2013
  8. Best oral presentation at the 14th Annual Meeting of the Portuguese Association for the study of the liver- 2011
  9. 1st Prize: Best communication in the XXI Congress of the Portuguese Society of Surgery-2011
  10. Ph.D. Scholarship – Portuguese Foundation for Science and Technology -2009

 

Publications

  1. Gomes AR, Abrantes AM, Brito AF, Laranjo M, Casalta-Lopes JE, Gonçalves AC, Sarmento-Ribeiro AB, Botelho MF, Tralhão JG, “P53 influence on the radiotherapeutic response of the hepatocellular carcinoma”, Clinical and molecular Hepatology, vol. 21, no. 3, 2015, pp. 257-267.
  2. Brito AF, Abrantes AM, Encarnação JC, Tralhão JG, Botelho MF, “Cholangiocarcinoma: from molecular biology to treatment”, Medical Oncology, vol. 32, no. 11, 2015, pp. 1-8.
  3. Brito AF, Ribeiro M, Abrantes AM, Pires AS, Teixo RJ, Tralhão JG, Botelho MF, “Quercetin in cancer treatment, alone or in combination with conventional therapeutics?”, Current Medicinal Chemistry, vol. 22, no. 26, 2015, pp. 3025-3039.
  4. Brito AF, Abrantes AM, Ribeiro M, Oliveira R, Casalta-Lopes J, Gonçalves AC, Sarmento-Ribeiro AB, Tralhão JG, Botelho MF, “Fluorine-18 Fluorodeoxyglucose
  5. Uptake in Hepatocellular Carcinoma: Correlation with Glucose Transporters and p53 Expression”, Journal of Clinical and Experimental Hepatology, vol. 5, no. 3, 2015, pp. 183-189.
  6. Cortez PP, Brito AF, Kapoor S, Correia AF, Atayde LM, Dias-Pereira P, Afonso A, Goel A, Ferreira JMF, “The in vivo performance of an alkali-free bioactive glass for bone grafting, FastOs®BG, assessed with an ovine model”, Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2015, doi: 10.1002/jbm.b.33529.
  7. Santos K, Laranjo M, Abrantes AM, Brito AF, Gonçalves AC, Sarmento-Ribeiro AB, Botelho MF, Soares MIL, Oliveira ASR, Pinho e Melo, TMVD, “Targeting triple-negative breast cancer cells with 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles”, European Journal of Medicinal Chemistry, vol. 79, no. 22, 2014, pp. 273-281.
  8. Mamede AC, Laranjo M, Carvalho MJ, Abrantes AM, Pires AS, Brito AF, Moura P, Maia CJ, Botelho MF, “Effect of amniotic membrane proteins in human cancer cell lines: an exploratory study”, J Membr Biol, vol. 274, no. 4, 2014, pp. 357-360.
  9. Brito AF, Mendes M, Abrantes AM, Tralhão JG, Botelho MF, “Positron Emission Tomography Diagnostic Imaging in Multidrug-Resistant Hepatocellular Carcinoma: Focus on 2-Deoxy-2-(18F)Fluoro-d-Glucose”, Molecular Diagnosis & Therapy, vol. 18, no. 5, 2014, pp. 495-504.
  10. Brito AF, Ribeiro M, Gonçalves AC, Sarmento-Ribeiro AB, Tralhão JG, Botelho MF, “Acção anti-cancerígena da Quercetina no Carcinoma Hepatocelular: o papel do GLUT-1”, Revista da Sociedade Portuguesa de Cirurgia, vol. 25, no. 1, 2013, pp. 23-30.
  11. Soares MIL, Brito AF, Laranjo M, Paixão JA, Botelho MF, Pinho e Melo TMVD, “Chiral 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles with anti-breast cancer properties”, European Journal of Medicinal Chemistry, vol. 60, no. 1, 2013, pp. 254-262.
  12. Brito AF, Abrantes AM, Pinto-Costa C, Gomes AR, Mamede AC, Casalta-Lopes J, Gonçalves AC, Sarmento-Ribeiro AB, Tralhão JG, Botelho MF, “Hepatocellular Carcinoma and Chemotherapy: The Role of p53”, Chemotherapy, vol. 58, no. 5, 2012, pp. 381-386.
  13. Catarino S, Bento CF, Brito A, Murteira E, Fernandes AF, Pereira P, “Regulation of the expression of interleukin-8 induced by 25-hydroxycholesterol in retinal pigment epithelium cells”, Acta Ophthalmologica, vol. 90, no. 4, 2012, pp. 255-263.
  14. Gomes AR, Abrantes AM, Costa CP, Mamede AC, Brito AF, Tralhão JG, Botelho MF, “Treatment of hepatocellular carcinoma with Cisplatin/Doxorubicin and 131-Iodine: Therapeutic Efficacy Study”, Radioprotecção, vol. 2, no. 18, 2011, pp. 5-8.
  15. Soares MIL, Brito AF, Laranjo M, Abrantes AM, Botelho MF, Paixão JA, Beja AM, Silva MR, Pinho e Melo TMVD, “Chiral 6-hydroxymethyl-1H,3H-pyrrolo[1,2-c]thiazoles: Novel antitumor DNA monoalkylating agents,” Journal Name, vol. 45, no. 10, 2010, pp. 4676-4681.
  16. Pires AS, Pinto M, Silveira P, Brito AF, Fonseca S, Castro I, Diaz S, Cunha AL, Ferreira M, Zambetti M, Lopes MC, Carreira I, Botelho MF, “Cytogenetic alterations induced by radiation in amniocytes,” Electrónica e Telecomunicações, vol. 4, no. 1, 2007, pp. 815-817.
  17.  Brito AF, Ribeiro AC, Abrantes AM, Mamede AC, Laranjo M, Casalta-Lopes J, Gonçalves AC, Sarmento-Ribeiro AB, Tralhão JG, Botelho MF, “New approach for treatment of primary liver tumors: the role of quercetin”, to be published in: Nutrition and Cancer.

 

 

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