peter-de-boves-harrington
Peter de Boves Harrington, Ph.D
Professor of Chemistry & Biochemistry

Ohio University Athens
Ohio City, Ohio, USA
Phone: 01-740-994-0265 (Office)
E-mail: Peter.Harrington@Ohio.edu

Education

  1888   Ph.D. (Analytical Chemistry), University of North Carolina, Chapel Hill, NC, Dissertation Advisor, Thomas L. Isenhour   US
        1980   B.S. (Chemistry), Randolph-Macon College, Ashland, VA   US

Biography

 

Research Interest

  • Intelligent analytical instrumentation
  • chemo metrics
  • micro scale sensors
  • ion mobility and mass spectrometry’s
  • automated and online decision-making
  • pattern recognition
  • artificial intelligence and novel representations of chemical information
  • Successful developments include fuzzy rule-building expert systems
  • temperature constrained neural networks
  • analysis of variance – principal component analysis (ANOVA-PCA)
  • generalized sensitivity analysis of neural networks
  • two-dimensional wavelet compression and modeling of sensor data
  • The Latin-partition bootstrap method for statistically evaluating classifiers.

Scientific Activities

  • CannaPrint, Board of Advisors, 2016-2017
  • Director of the Forensic Chemistry Programs, 2012-2015
  • Visiting Scholar, Universitetet i Agder, Kristiansand, NO, August, 2010.
  • Director of the Master of Science Program in Forensic Chemistry, 2009-2015
  • Chercheur Etranger, Université Paul Cézanne, Marseille, FR September-December, 2008.
  • Summer Visiting Fellow (ORISE) Food and Drug Administration/Center for Food Safety and Applied Nutrition, MD, June-August, 2007
  • Summer Visiting Fellow (Contractor) National Institutes of Health/National Institute of Mental Health, Bethesda, MD, July-August, 2005
  • Director of the Forensic Chemistry Program, 2004-2009
  • Professor, Ohio University, 2004-Present
  • Summer Faculty Fellow, Idaho National Engineering and Environmental Laboratory, Idaho Falls, ID, June-July, 2003
  • Director, Ohio University Center for Intelligent Chemical Instrumentation, 2002- Present
  • Faculty Fellow, Idaho National Engineering and Environmental Laboratory, Idaho Falls, ID, 2001-2002
  • Associate Professor, Ohio University, 1995-2004 (Tenured 1995)
  • Adjunct Professor Environmental Science, Ohio University, 1994-Present
  • Assistant Professor, Ohio University, 1989-1995
  • Research Assistant Professor, The Colorado School of Mines, Golden, CO, 1988- 1989
  • Research Associate, The Colorado School of Mines, Golden, CO, 1987-1988
  • Flavor Chemist, Nabisco Brands Inc., Wilton, CT, 1980-1982

Awards and Recognition

  • Analytics (Editorial Advisory Board, 2017-)
  • Investigative Forensic Sciences (Editor, 2016-)
  • Journal of Analysis and Testing (Editorial Advisory Board, 2016-)
  • Ohio University College of Arts & Sciences Outstanding Faculty Research Award (2016)
  • Nature: Scientific Reports (Editorial Board Member 2015-)
  • Fellow of the American Academy of Forensic Sciences (2015-)
  • International Journal of Spectroscopy (Editor, 2007-2017).
  • Award for Academic Achievement, North East Normal University, Changchun, PRC, December 7, 2006.
  • Research Opportunity Award, the Research Corporation 2001-2003.
  • Appointed Visiting Professor at North East Normal University, Changchun, PRC, 2001.
  • Analytica Chimica Acta (Editorial Advisory Board, 1997-2000)
  • Analytica Chimica Acta (Editorial Advisory Board, 2003-2005)
  • Chemometrics and Intelligent Laboratory Instruments (Editorial Advisory Board, 1991-)
  • Critical Reviews in Analytical Chemistry (Editorial Advisory Board, 2013-)
  • Journal of Spectroscopy and Dynamics (2010-)
  • Talanta (Editorial Advisory Board, 2005-2010)
  • Analytical Sciences Digital Library (Contributing Editor 2003-2005)
  • “The Future of Spectroscopy: Bright Young Stars” Spectroscopy, October 1995, 60.

Professional Affiliations

  • American Academy of Forensic Sciences (Criminalistics, 2008- ) Fellow, 2015-
  • Commissioner, Forensic Science Education Programs Accreditation Commission (FEPAC), 2008-2009.
  • American Chemical Society (1980-2009)
  • Forensic Science Institute of Ohio
  • International Chemo metrics Society
  • International Society for Ion Mobility Spectrometry
    Steering Committee (2005-2007)
    Secretary (2006-2007)
  • International Forensic Science Education Consortium
  • New York Academy of Sciences (Lifetime Member)
  • North American Academy of Arts & Sciences Fellow (Lifetime Member)
  • Society for Analytical Chemists of Pittsburgh (Lifetime Member)
  • Society for Applied Spectroscopy
  • Sigma Xi Secretary (2012-present) Local Section Ohio University, Athens, OH
  • Sigma Xi President (2005-2012) Local Section Ohio University, Athens, OH


Publications

  1. A.K. Aloglu, P.B. Harrington*, S. Sahin, C. Demir, and M.E. Gunes, Chemical Profiling of Floral and Chestnut Honey using High-Performance Liquid Chromatography-Ultraviolet Detection, Journal of    Food Composition and Analysis (2017) DOI: 10.1016/j.jfca.2017.06.002.
  2. Y. Mao, L. Yu*, R. Yang, C. Ma, L. Qu*, P.B. Harrington, New peptide inhibitors modulate the self-assembly of islet amyloid polypeptide residues 11-20, European Journal of Pharmacology (2017) 804 102-110 DOI: 10.1016/j.ejphar.2017.03.015.
  3. P.B. Harrington* and X. Wang, Spectral Representation of Proton NMR Spectroscopy for the Pattern Recognition of Complex Materials, Journal of Analysis and Testing (2017) 1:10 DOI: 10.1007/s41664-017-0003-y.
  4. P.B. Harrington*, Automated Support Vector Regression, Journal of Chemometrics (2017) 31 1-14 DOI: 10.1002/cem.2867.
  5. P.B. Harrington*, Support Vector Machine Classification Trees Based on Fuzzy Entropy of Classification, Analytica Chimica Acta (2017) 954 14-21 DOI: 10.1016/j.aca.2016.11.072.
  6. A.K. Aloglu, P.B. Harrington*, S. Sahin, C. Demir, Prediction of Total Antioxidant Activity of Prunella L. Species by Automatic Partial Least Square Regression Applied to 2-Way Liquid Chromatographic UV Spectral Images. Talanta (2016) 161 503-510 DOI: 10.1016/j.talanta.2016.09.014.
  7. N.R. Saichek, C.R Cox, S. Kim, P.B. Harrington, N.R. Stambach and K.Voorhees*, Strain-level Staphylococcus differentiation by CeO2-metal oxide laser ionization mass spectrometry fatty acid profiling. BMC Microbiology (2016) 16:72 1-11 DOI: 10.1186/s12866-016-0658-y.
  8. Z. Chen, Z. Zhang*, R. Zhu, Y. Xiang, and P.B. Harrington, Diagnosis of patients with chronic kidney disease by using two fuzzy classifiers. Chemometrics and Intelligent Laboratory Systems (2016) 153 140-145 DOI: 10.1016/j.chemolab.2016.03.004.
  9. J. Li, J. Qu, L. Qu, R. Yang*, P.B. Harrington, A sensitive electrochemical sensor of quercetin based on graphene quantum dots/gold nanoparticles nanocomposite. Electrochimica Acta (2016) 28:6 1322-1330 DOI: 10.1002/elan.201500490.
  10. J.M. Harnly*, P. Chen, J. Sun, H. Huang, K. Colson, J. Yuk, J.A. McCoy, D.H. Reynaud, and P.B. Harrington, MS, NMR, and DNA Barcoding, Complementary Methods for Identification and Authentication of Black Cohosh (Actaea racemosa L.). Planta Medica (2015) 82:03 250-262 DOI: 10.1055/s-0035-1558113.
  11. Y. Mao, L. Yu, R. Yang, C. Ma, L. Qu, and P.B. Harrington, New insights into side effect of solvents on the aggregation of human islet amyloid polypeptide 11–20. Talanta (2015) 148 380-386 DOI:  0.1016/j.talanta.2015.11.012.
  12. P.B. Harrington*, Support Vector Machine Classification Trees. Analytical Chemistry (2015) 87:21 11065-11071 DOI: 10.1021/acs.analchem.5b03113.
  13. J. Harnly*, P. Chen, K. Colson, J.A. McCoy, D.H. Reynaud, and P.B. Harrington, MS, NMR, and DNA barcoding, complementary methods for identification and authentication of Black Cohosh (Actaea racemosa L.). Planta Medica (2015) 81:11 PA1 DOI: 10.1055/s-0035-1556184.
  14. R. Yang*, D. Miao, Y. Liang, L. Qu, J. Li, P.B. Harrington, Ultrasensitive electrochemical sensor based on CdTe quantum dots-decorated poly(diallyldimethylammonium chloride)-functionalized grapheme nanocomposite modified glassy carbon electrode for the determination of puerarin in biological samples. Electrochimica Acta (2015) 173:10 839-846 DOI: 10.1016/j.electacta.2015.05.139.
  15. Z. Zhang*, Z. Chen, R. Zhu, Y. Xiang, Y. Yang, and P.B Harrington, Application of Terahertz Time-Domain Spectroscopy Combined with Chemometrics to Quantitative Analysis of Imidacloprid in Rice Samples. Journal of Quantitative Spectroscopy and Radiative Transfer (2015) 167 1-9 DOI: 10.1016/j.jqsrt.2015.07.018.
  16. A.H. Bani Rashaid, P.B. Harrington*, and Glen P. Jackson Profiling Amino Acids of Jordanian Scalp Hair as a Tool for Diabetes Mellitus Diagnosis. Analytical Chemistry (2015) DOI: 10.1021/acs.analchem.5b00460.
  17. M. Zhang, Y. Zhao, P.B. Harrington, and Pei Chen*, Differentiation of Aurantii Fructus Immaturus and Fructus Poniciri Trifoliatae Immaturus by Flowinjection with Ultraviolet Spectroscopic Detection and Proton Nuclear Magnetic Resonance using Partial Least-squares Discriminant Analysis. Analytical Letters (2015) 10.1080/00032719.2015.1045588.
  18. M. Zhang, P.B. Harrington, and P. Chen*, Classification of Cultivation Locations of Black Pepper (Piper nigrum L.) using Gas Chromatography and Chemometrics. Current Chromatography (2015) 2 1-1 DOI: 10.2174/2213240602666150518235059.
  19. L. Wang, R. Yang*, J. Li, L. Qu, and P.B. Harrington, High-sensitive electrochemical sensor of Sudan I based on template-directed self-assembly of graphene-ZnSe quantum dots hybrid structure. Sensors and Actuators BChemical (2015) 215 181-187 DOI: 10.1016/j.snb.2015.03.034.
  20. M. Zhang and P.B. Harrington*, Application of Chemometrics to Resolve Overlapping Mass Spectral Peak Clusters Between Trichloroethylene and its Deuterated Internal Standard. Rapid Communications in Mass Spectrometry (2015) 29 789-794 DOI: 10.1002/rcm.7164.
  21. G. Downey, L.L. Botros*, J. Jablonski, C. Chang, M.M. Bergana, P. Wehling, J.M. Harnly, P.B. Harrington, A.R. Potts, and J.C. Moore, Exploring the variance of authentic skim and non-fat dry milk powder spectra. NIR News (2015) 26:2 11-14 DOI: 10.1255/nirn.1512.
  22. M. Zhang and P.B. Harrington*, Determination of Trichloroethylene in Water by Liquid-Liquid Microextraction Assisted Solid Phase Microextraction. Chromatography (2015) 2:1 66-78 DOI: 10.3390/chromatography2010066.
  23. L. Wang, R. Yang*, H. Wang, J. Li, L. Qu*, and P.B. Harrington, Highselective and sensitive voltammetric sensor for butylated hydroxyanisole based on AuNPs-PVP-graphene nanocomposites. Talanta 138:1 (2015) 169- 175 DOI: 10.1016/j.talanta.2015.01.016.
  24. Y. Mao, L. Yu*, J. Li, L. Qu*, and P.B. Harrington, A novel method for the study of molecular interaction by using microscale thermophoresis. Talanta 132 (2015) 894-901 DOI: 10.1016/j.talanta.2014.09.038.
  25. N. Qi, Z. Zhang*, Y. Xiang, Y. Yang, X. Liang, and P.B. Harrington, Terahertz time-domain spectroscopy combined with support vector machines and partial least squares-discriminant analysis applied for the diagnosis of cervical carcinoma. Analytical Methods 7:6 (2015) 2333-2338 DOI: 10.1039/C4AY02665A.
  26. A.H. Bani Rashaid, P.B. Harrington, and G.P. Jackson*, Amino Acid Composition of Human Scalp Hair as a Biometric Classifier and Investigative Lead. Analytical Methods 7:5 (2015) 1707-1718 DOI: 10.1039/C4AY02588A.
  27. N. Qi, Z. Zhang*, Y. Xiang, Y. Yang, and P.B. Harrington, Terahertz Timedomain Spectroscopy Combined with Fuzzy Rule-building Expert System and Fuzzy Optimal Associative Memory Applied to Early Diagnosis of Cervical Carcinoma. Medical Oncology 32:1 (2014) 1-6 DOI: 10.1007/s12032-014- 0383-z.
  28. K.J. Voorhees*, N.R. Saichek, K.R. Jensen, C.R. Cox, and P.B. Harrington, Comparison of Metal Oxide Catalysts for Pyrolytic MALDI-TOF MS Bacterial Identification. Journal of Analytical and Applied Pyrolysis (2014) DOI: 10.1016/j.jaap.2014.10.016.
  29. Z. Wang, L. Lin, J.M. Harnly, P.B. Harrington, and P. Chen*, Computer-aided method for identification of major flavone/flavonol glycosides by highperformance liquid chromatography-diode array detection-tandem mass spectrometry (HPLC-DAD-MS/MS). Analytical and Bioanalytical Chemistry 406 (2014) 7695-7704 DOI: 10.1007/s00216-014-8187-8.
  30. D. Miao, J. Li, R. Yang*, J. Qu, L. Qu, and P.B. Harrington, Supersensitive electrochemical sensor for the fast determination of rutin in pharmaceuticals and biological samples based on poly(diallyldimethylammonium chloride)- functionalized graphene. Journal of Electro analytical Chemistry 732 (2014)17-24 DOI: 10.1016/j.jelechem.2014.08.018.
  31. M. Zhang and P.B. Harrington*, Simultaneous Quantification of Aroclor Mixtures in Soil Samples by Gas Chromatography/Mass Spectrometry with Solid Phase Micro extraction using Partial Least-Squares Regression.Chemosphere 118C (2014) 187-193, DOI: 10.1016/j.chemosphere.2014.08.018.
  32. Z. Wang, M. Zhang, and P.B. Harrington*, A Comparison of Three Algorithms for the Baseline Correction of Hyphenated Data Objects. Analytical Chemistry 86:18 (2014) 9050-9057, DOI: 10.1021/ac501658k.
  33. L. Wang, R. Yang*, J. Chen, J. Li, L. Qu*, and P.B. Harrington, Sensitive voltammetric sensor based on Isopropanol–Nafion–PSS–GR nanocomposite modified glassy carbon electrode for determination of Clenbuterol in pork. Food Chemistry 164 (2014) 113-118, DOI: 10.1016/j.foodchem.2014.04.052.
  34. A.H. Bani Rashaid, G.P. Jackson, and, P.B Harrington*, Validation of a Method of Measuring the Amino Acid Composition of Proteins by Gas Chromatography/Mass Spectrometry. Enliven: Bio Analytical Techniques 1:002 (2014), http://www.enlivenarchive.org/bioanalytical-002.pdf.
  35. M. Zhang, G.P. Jackson, N.A. Kruse, J.R. Bowman, and P.B. Harrington*, Determination of Aroclor 1260 in Soil Samples by GC-MS with Solid-Phase Microextraction. Journal of Separation Science 118 (2014) 187-193, DOI: 10.1002/jssc.201400102.
  36. J. M. Harnly*, P.B. Harrington*, L.L. Botros, J.E. Jablonski, C. Chang, M.M. Bergana, P. Wehling , G. Downey, A.R. Potts , and J.C. Moore, Characterization of Near Infrared Spectral Variance in the Authentication of Skim and Nonfat Dry Milk Powder Collection Using ANOVA-PCA, Pooled- ANOVA, and Partial Least Squares Regression. Journal of Agriculture and Food Chemistry 62:32 (2014) 8060-8067, DOI: 10.1021/jf5013727.
  37. J. Wang, Z. Zhang*, Z. Zhang, Y. Xiang, and P.B. Harrington, THz-TDS combined with a fuzzy rule-building expert system applied to identification of official rhubarb samples. Analytical Methods 6:19 (2014) 7695-7702, DOI: 10.1039/C4AY00555D.
  38. P.B. Harrington*, Fuzzy Grid Encoded Independent Modeling for Class Analogies (FIMCA). Analytical Chemistry 86:10 (2014) 4883-4892, DOI: 10.1021/ac5001543.
  39. J. Li, D. Miao, R. Yang, L. Qu, and P.B. Harrington, Synthesis of poly(sodium 4-styrenesulfonate) functionalized graphene/cetyltrimethylammonium bromide (CTAB) nanocomposite and its application in electrochemical oxidation of 2,4-dichlorophenol. Electrochimica Acta 125 (2014) 1-8.
  40. F. Yu, S. Yu, L. Yu, Y. Li, Y. Wu*, H. Zhang, L. Qu, P.B. Harrington, Determination of residual enrofloxacin in food samples by a sensitive method of chemiluminescence enzyme immunoassay. Food Chemistry 149 (2014) 71-75 DOI: 10.1016 /j.foodchem.2013.10.024.
  41. J.M. Harnly*, P. Chen, and P.B. Harrington, Probability of Identification: Adulteration of American Ginseng with Asian Ginseng. Journal of AOAC International 96 (2013) 1258-1265 DOI: 10.5740/jaoacint.13-290.
  42. M. Zhang and P.B. Harrington*, Automated Pipeline for Classifying Aroclors in Soil by Gas Chromatography/Mass Spectrometry using Modulo Compressed Two-way Data Objects, Talanta 117 (2013) 483-491 DOI: 10.1016/j.talanta.2013.09.050.
  43. H. Zhang, Y. Wu*, F. Yu, S. Yu, H. Zhang, L. Qu, P.B. Harrington, Study on the reaction mechanism and the static injection chemiluminescence method for detection of acetaminophen, Luminescence 28:6 (2013) 905-909 DOI: 10.1002/bio.2455.
  44. Z. Wang and P.B. Harrington*, Feature Selection from Gas Chromatography/Mass Spectrometry Data Using a Bootstrapped Fuzzy Rule- Building Expert System, Analytical and Bioanalytical Chemistry 405 (2013) 9219-9234, DOI: 10.1007/s00216-013-7327-x.
  45. J. Li, X. Li, R. Yang*, L. Qu, and P.B. Harrington, A sensitive electrochemical chlorophenol sensor based on nanocomposite of ZnSe quantum dots and cetyltrimethylammonium bromide, Analytica Chimica Acta 804 (2013) 76-83, DOI: 10.1016/j.aca.2013.09.049.
  46. L. Botros, J.E. Jablonski , C. Chang , M.M. Bergana , P. Wehling , J.M. Harnly, G. Downey, P.B. Harrington, A.R. Potts , and J.C. Moore, Exploring Authentic Skim and Nonfat Dry Milk Powder Variance for the Development of Nontargeted Adulterant Detection Methods Using NIR Spectroscopy and Chemometrics. Journal of Agriculture and Food Chemistry 61:41 (2013) 9810-9818, DOI: 10.1021/jf4023433.
  47. G. Wang, M. Ma, Z. Zhang*, Y. Xiang, and P.B. Harrington, A novel DPSO– SVM system for variable interval selection of endometrial tissue sections by near infrared spectroscopy. Talanta 112 (2013) 136-142, DOI: 10.1016/j.talanta.2013.03.016.
  48. Z. Wang, P. Chen, L. Yu, and P.B. Harrington*, Authentication of Organically and Conventionally Grown Basil by Gas Chromatography/Mass Spectrometry Chemical Profiles. Analytical Chemistry 85:5 (2013) 2945-2953, DOI: 10.1021/ac303445v.
  49. N. Qi, Z. Zhang*, Y. Xiang, and P.B. Harrington, Locally linear embedding method for dimensionality reduction of tissue sections of endometrial carcinoma by near infrared spectroscopy. Analytica Chimica Acta 724 (2012) 12-19.
  50. F. Yu, Y. Wu*, S. Yu, H. Zhang, H. Zhang, L. Qu, and P.B. Harrington, A competitive chemiluminescence enzyme immunoassay for rapid and sensitive determination of enrofloxacin. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 93 (2012) 164-168.
  51. Z. Wang, Y. Zhang, H. Zhang, P.B. Harrington*, H. Chen*, Fast and Selective Modification of Thiol Proteins/Peptides by N-(Phenylseleno) phthalimide, Journal of the American Society for Mass Spectrometry 23:3 (2012) 520-529 DOI: 10.1007/s13361-011-0317-3.
  52. X. Sun, P. Chen, S. Cook, G.P. Jackson, J.M. Harnly, P.B. Harrington*, Classification of Cultivation Locations of Panax Quinquefolius L Samples using High Performance Liquid Chromatography-Electrospray Ionization Mass Spectrometry and Chemometric Analysis, Analytical Chemistry 84:18 (2012) 3628–3634.
  53. F. Yang, J. Tian, Y. Xiang, Z. Zhang*, and P.B. Harrington, Near infrared spectroscopy combined with least squares support vector machines and fuzzy rule-building expert system applied to diagnosis of endometrial carcinoma. Cancer Epidemiology 36:3 (2012) 317-323 DOI: 10.1016/j.canep.2011.10.009.
  54. J. Harnly*, P. Chen and P. B. Harrington, Detection of Adulterated Botanicals. Planta Medica 77:5 (2011) P_36 DOI: 10.1055/s-0031-1273565.
  55. P. Chen*, D. Luthria, P.B. Harrington, and J.M. Harnly, Discrimination between Panax Species using Spectral Fingerprinting. Journal of AOAC International 94:5 (2011) 1411-1421.
  56. Z. Xu, X. Sun, P.B. Harrington*, Baseline Correction Method Using an Orthogonal Basis for Gas Chromatography/Mass Spectrometry Data. Analytical Chemistry, 83:19 (2011) 7464-7471 DOI: 10.1021/ac2016745.
  57. X. Sun, Z. Miao, P.B. Harrington*, J. Colla, and H. Chen*, Coupling of single droplet micro-extraction with desorption electrospray ionization-mass spectrometry. International Journal of Mass Spectrometry, 301:1-3 (2011) 102-108.
  58. P. Chen*, J. M. Harnly, P.B. Harrington, Flow Injection Mass Spectroscopic Fingerprinting and Multivariate Analysis for Differentiation of Three Panax Species. Journal of AOAC International, 94:1 (2011) 90-99.
  59. W. Lu, J.H. Callahan, F. Fry, D. Andrzejewski, S.M. Musser, and P.B. Harrington*, A discriminant based charge deconvolution analysis pipeline for protein profiling of whole cell extracts using liquid chromatographyelectrospray ionization-quadrupole time-of-flight mass spectrometry. Talanta, 84:4 (2011) 1180-1187.
  60. J. Zhang, Z. Zhang*, Y. Xiang, Y. Dai, and P.B. Harrington, An emphatic orthogonal signal correction-support vector machine for the classification of tissue sections of endometrial carcinoma. Talanta, 83:5 (2011) 1401-1409.
  61. X. Sun, C.M. Zimmermann, G.P. Jackson, C.E. Bunker, and P.B. Harrington*, Classification of Jet Fuels by Fuzzy Rule-Building Expert Systems Applied to Two-Way Data by Fast Gas Chromatography-Fast Scanning Quadrupole Ion Trap Mass Spectrometry. Talanta, 83:4 (2011) 1260-1268.
  62. Z. Xu, C.E. Bunker, and P.B. Harrington*, Classification of Jet Fuel Properties by Near Infrared Spectroscopy Using Fuzzy Rule-Building Expert Systems and Support Vector Machines. Applied Spectroscopy, 64:11 (2010) 1251-1258.
  63. Y. Lu and P.B. Harrington*, Classification of bacteria by simultaneous methylation–solid phase microextraction and gas chromatography/mass spectrometry analysis of fatty acid methyl esters. Analytical and Bioanalytical Chemistry, 397 (2010) 2959-2966.
  64. A. Baum, Y. Lu, Z. Muccio, G.P. Jackson, and P.B. Harrington*, Differentiation between origins of extra virgin olive oils by GC/C/IRMS using principal component analysis, linear discriminant analysis and hierarchical cluster analysis. Spectroscopy, 25:2 (2010) 40-47.
  65. Y. Xiang, Z. Zhang*, Y. Dai, and P.B. Harrington, Near-infrared spectroscopic applications for diagnosis of endometrial carcinoma. Biomedical Optics, 15:6 (2010) 067002, DOI: 10.1117/1.3512183.
  66. W. Lu and P.B. Harrington*, Radial Basis Function Cascade Correlation Networks. Algorithms, 2 (2009) 1045-1068.
  67. Y. Lu, R.M. O'Donnell, and P.B. Harrington*, Detection of Cocaine and Its Metabolites in Urine Using Solid Phase Extraction–Ion Mobility Spectrometry with Alternating Least Squares. Forensic Science International, 189 (2009) 54-59.
  68. Y. Lu, P. Chen, and P.B. Harrington*, Comparison of Differential Mobility Spectrometry and Mass Spectrometry for Gas Chromatographic Detection of Ignitable Liquids from Fire Debris Using Projected Difference Resolution. Analytical and Bioanalytical Chemistry, 394 (2009) 2061-2067, DOI: 10.1007/s00216-009-2786-9.
  69. P.B. Harrington*, J. Kister, J. Artaud, and N. Dupuy, Automated Principal Component-Based Orthogonal Signal Correction Applied to Fused Near Infrared-Mid Infrared Spectra of French Olive Oils. Analytical Chemistry, 81:17 (2009) 7160-7169, DOI: 10.1021/ac900538n.
  70. A.A. Christy*, Z. Xu, and P.B. Harrington, Thermal degradation and isomerisation kinetics of triolein studied by infrared spectrometry and GC–MS combined with chemometrics. Chemistry and Physics of Lipids, 158:1 (2009) 23-31.
  71. P. Chen, Y. Lu, and P.B. Harrington*, Application of Linear and Nonlinear Discrete Wavelet Transforms to MALDI-MS Measurements of Bacteria for Classification. Analytical Chemistry, 80:19 (2008) 7218-7225, 10.1021/ac8004549.
  72. P. Chen, Y. Lu, and P.B. Harrington*, Biomarker Profiling and Reproducibility Study of MALDI-MS Measurements of Escherichia coli by Analysis of Variance-Principal Component Analysis. Analytical Chemistry, 80:5 (2008) 1474-1481.
  73. P. Chen and P.B. Harrington*, Discriminant Analysis of Fused Positive and Negative Ion Mobility Spectra Using Multivariate Self-Modeling Mixture Analysis and Neural Networks. Applied Spectroscopy, 62:2 (2008) 133-141.
  74. R.M. O’Donnell, X. Sun, and P.B. Harrington*, Pharmaceutical Applications of Ion and Differential Mobility Spectrometries. Trends in Analytical Chemistry, 27:1 (2008) 44-53.
  75. P.B. Harrington*, C. Laurent, D.F. Levinson, P. Levitt, and S.P. Markey, Bootstrap Classification and Point-Based Feature Selection from Age-Staged Mouse Cerebellum Tissues of Matrix Assisted Laser Desorption/Ionization Mass Spectra using a Fuzzy Rule-Building Expert System. Analytica Chimica Acta, 599 (2007) 219-231.
  76. Yao Lu and P.B. Harrington*, Forensic Application of Gas Chromatography- Differential Mobility Spectrometry with Two-Way Classification of Ignitable Liquids from Fire Debris. Analytical Chemistry, 79:17 (2007) 6752-6759.
  77. Z.Y. Zhang*, Y.M. Wang, G.Q. Fan, and P.B. Harrington, A comparative study of multilayer perceptron neural networks for the identification of rhubarb samples. Phytochemical Analysis, 18 (2007) 109-114.
  78. P. Rearden and P.B. Harrington*, Fuzzy Rule-Building Expert System Classification of Fuel Using Solid Phase Microextraction Two-Way Gas Chromatography Differential Mobility Spectrometric Data. Analytical Chemistry, 79:4 (2007) 1485-1491.
  79. P.B. Harrington*, Statistical Validation of Classification and Calibration Models Using Bootstrapped Latin Partitions. Trends in Analytical Chemistry, 25:11 (2006) 1112-1124, DOI: 10.1016/j.trac.2006.10.010.
  80. F. Wang, Z. Zhang*, X. Cui, P.B. Harrington, Identification of rhubarbs by using NIR spectrometry and temperature-constrained cascade correlation networks. Talanta, 70 (2006) 1170-1176.
  81. X. Cui, Z. Zhang*, X. Yuan, J. Zhang, S. Liu, L. Guo, and P.B. Harrington, Application of Density Functional Theoretic Descriptors to Quantitative Structure Activity Relationships with Temperature Constrained Cascade Correlation Network Models of Nitrobenzene Derivatives. Chemical Research in Chinese Universities, 22:4 (2006) 439-442.
  82. Z. Zhang*, H. Zhou, S. Liu, and P.B. Harrington, An Application of Takagi- Sugeno Fuzzy System to the Classification of Cancer Patients Based on the Elemental Contents in Serum Samples. Chemometrics and IntelligentnLaboratory Systems, 82 (2006) 294-299.
  83. P.B. Harrington*, N.E. Vieira, P. Chen, J. Espinoza, J.K. Nien, R. Romero, and A.L. Yergey, Proteomic Analysis of Amniotic Fluids Using Analysis of Variance- Principal Component Analysis and Fuzzy Rule-Building Expert Systems Applied to Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry. Chemometrics and Intelligent Laboratory Systems, 82 (2006) 283-293.
  84. P. Rearden and P.B. Harrington*, Detection of VOCs Using Gas Chromatography-Differential Mobility Spectrometry (GC-DMS). LabPlus International, 20:1 (2006) 20-24 (http://www.labplusinternational.com/artimg/a20061217243159.PDF).
  85. G.M. Bota and P.B. Harrington*, Direct Detection of Trimethylamine in Meat Food Products Using Ion Mobility Spectrometry. Talanta, 68:3 (2006) 629- 635.
  86. R.V. Fox*, R.D. Ball, P.B. Harrington, H.W. Rollins, and C.M. Wai, Holmium Nitrate Complexation with Tri-n-butyl Phosphate in Supercritical Carbon Dioxide. Journal of Supercritical Fluids, 36:2 (2005) 137-144.
  87. Z.Y. Zhang*, G. Chen, and P.B. Harrington, Detection of trace organic compounds by using ion mobility spectrometry and SIMPLISMA. Spectroscopy and Spectral Analysis, 25:9 (2005) 1530-1533.
  88. C. Laurent*, D.F. Levinson, S.A. Schwartz, P.B. Harrington, S.P. Markey, R.M. Caprioli, and P. Levitt, Direct Profiling of the Cerebellum by MALDI MS: A Methodological Study in Postnatal and Adult Mouse. Journal of Neuroscience Research, 81:5 (2005) 613-621.
  89. Z. Zhang* and P.B. Harrington, Recent Studies on Artificial Neural Networks and Their Application. Current Topics in Analytical Chemistry, 5 (2005) 24- 41.
  90. M.L. Ochoa and P.B. Harrington*, Immunomagnetic Isolation of Enterohemorrhagic Escherichia coli O157:H7 from Ground Beef and Identification by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry and Database Searches. Analytical Chemistry, 77 (2005) 5258-5267.
  91. M.R. Rainsberg and P.B. Harrington*, Thermal Desorption Solid-Phase Microextraction Inlet for Differential Mobility Spectrometry. Applied Spectroscopy, 59 (2005) 754-762.
  92. P. Rearden and P.B. Harrington*, Rapid Screening of Precursor and Degradation Products of Chemical Warfare Agents in Soil by Solid-Phase Microextraction Ion Mobility Spectrometry (SPME-IMS). Analytica Chimica Acta, 545 (2005) 13-20.
  93. P.B. Harrington*, N.E. Vieira, J. Espinoza, J.K. Nien, R. Romero, and A.L. Yergey, Analysis of Variance-Principal Component Analysis: A Soft Tool for Proteomic Discovery. Analytica Chimica Acta, 544 (2005) 118-127.
  94. L. Cao, P.B. Harrington*, and J. Liu, SIMPLISMA and ALS Applied to Twodimensional Nonlinear Wavelet Compressed Ion Mobility Spectra of Chemical Warfare Agent Simulants. Analytical Chemistry, 77:8 (2005) 2575-2586.
  95. M.L. Ochoa and P.B. Harrington*, Chemometric Studies for the Characterization and Differentiation of Microorganisms Using in Situ Derivatization and Thermal Desorption Ion Mobility Spectrometry. Analytical Chemistry, 77 (2005) 854-863.
  96.  X.J. Cui, Z.Y. Zhang*, P.B. Harrington, and Y.L. Ren, Quality control of the powder pharmaceutical samples of metronidazole based on near infrared reflectance spectra with temperature-constrained cascade correlation neural networks. Chemical Journal of Chinese Universities, 25:7 (2004) 1251-1253.
  97. R.V. Fox*, R.D. Ball, P.B. Harrington, H.W. Rollins, J.J. Jolley, and C.M. Wai, Praseodymium Nitrate and Neodymium Nitrate Complexation with Organophosphorus Reagents in Supercritical Carbon Dioxide Solvent. Journal of Supercritical Fluids, 31 (2004) 273-286.
  98. Z. Zhang*, D. Wang, P.B. Harrington, K.J. Voorhees, and J. Rees, Forward Selection Radial Basis Function Networks Applied to Bacterial Classification Based on MALDI-TOF-MS. Talanta, 63 (2004) 527-532.
  99. L. Cao and P.B. Harrington*, Two-dimensional Nonlinear Wavelet Compression (NLWC) of Ion Mobility Spectra of Chemical Warfare Agent Simulants. Analytical Chemistry, 76 (2004) 2859-2868.
  100. M. Ochoa and P.B. Harrington*, Detection of Methamphetamine in the Presence of Nicotine Using In Situ Chemical Derivatization and Ion Mobility Spectrometry. Analytical Chemistry, 76 (2004) 985-991.
  101. P. Rearden and P.B. Harrington*, Rapid Screening of Precursor and Degradation Products of Chemical Warfare Agents in Soil by Solid-Phase Microextraction Ion Mobility Spectrometry (SPME-IMS). Analytica Chimica Acta, 545 (2005) 13-20.
  102. P.B. Harrington*, N.E. Vieira, J. Espinoza, J.K. Nien, R. Romero, and A.L. Yergey, Analysis of Variance-Principal Component Analysis: A Soft Tool for Proteomic Discovery. Analytica Chimica Acta, 544 (2005) 118-127.
  103. L. Cao, P.B. Harrington*, and J. Liu, SIMPLISMA and ALS Applied to Twodimensional Nonlinear Wavelet Compressed Ion Mobility Spectra of Chemical Warfare Agent Simulants. Analytical Chemistry, 77:8 (2005) 2575-2586.
  104. M.L. Ochoa and P.B. Harrington*, Chemometric Studies for the Characterization and Differentiation of Microorganisms Using in Situ Derivatization and Thermal Desorption Ion Mobility Spectrometry. Analytical Chemistry, 77 (2005) 854-863.
  105. X.J. Cui, Z.Y. Zhang*, P.B. Harrington, and Y.L. Ren, Quality control of the powder pharmaceutical samples of metronidazole based on near infrared reflectance spectra with temperature-constrained cascade correlation neural networks. Chemical Journal of Chinese Universities, 25:7 (2004) 1251-1253.
  106. X.J. Cui, Z.Y. Zhang*, Y.L. Ren, and P.B. Harrington, Quality control of the powder pharmaceutical samples of sulfaguanidine by using NIR reflectance spectrometry and temperature-constrained cascade correlation networks. Talanta, 64:4 (2004), 943-948.
  107. R.V. Fox*, R.D. Ball, P.B. Harrington, H.W. Rollins, J.J. Jolley, and C.M. Wai, Praseodymium Nitrate and Neodymium Nitrate Complexation with Organophosphorus Reagents in Supercritical Carbon Dioxide Solvent. Journal of Supercritical Fluids, 31 (2004) 273-286.
  108. Z. Zhang*, D. Wang, P.B. Harrington, K.J. Voorhees, and J. Rees, Forward Selection Radial Basis Function Networks Applied to Bacterial Classification Based on MALDI-TOF-MS. Talanta, 63 (2004) 527-532.
  109. L. Cao and P.B. Harrington*, Two-dimensional Nonlinear Wavelet Compression (NLWC) of Ion Mobility Spectra of Chemical Warfare Agent Simulants. Analytical Chemistry, 76 (2004) 2859-2868.
  110. M. Ochoa and P.B. Harrington*, Detection of Methamphetamine in the Presence of Nicotine Using In Situ Chemical Derivatization and Ion Mobility Spectrometry. Analytical Chemistry, 76 (2004) 985-991.
  111. A. Mehay, C. Cai, and P.B. Harrington*, Regularized Linear Discriminant Analysis of Wavelet Compressed Ion Mobility Spectra. Applied Spectroscopy, 56:2 (2002), 219-227.
  112. 116) P.B. Harrington*, K.J. Voorhees, F. Basile, and A.D. Hendricker, Validation Using Sensitivity and Target Transform Factor Analyses of Neural Network Models for Classifying Bacteria from Mass Spectra. Journal of the American Society of Mass Spectrometry, 13 (2002) 10-21.
  113. P.B. Harrington* and C. Wan, Sensitivity analysis applied to artificial neural networks: what has my neural network actually learned? International Journal of Ion Mobility Spectrometry, 5 (2002) 1-18.
  114. A.A. Urbas and P.B. Harrington*, Two-Dimensional Wavelet Compression of Ion Mobility Spectra. Analytica Chimica Acta, 446 (2001) 393-412
  115. P.B. Harrington*, T.L. Buxton G. Chen, Classification of Bacteria by Thermal Methylation Hydrolysis Ion Mobility Spectrometry Using SIMPLISMA and Multidimensional Wavelet Compression. International Journal of Ion Mobility Spectrometry, 4:2 (2001) 148-153.
  116. P.B. Harrington*, G. Chen, and A.A. Urbas, Strategies for Smarter Chemical Sensors. International Journal of Ion Mobility Spectrometry, 4:1 (2001) 26- 30.
  117. P.B. Harrington*, P.J. Rauch, and C. Cai, Multivariate Curve Resolution of Wavelet and Fourier Compressed Spectra. Analytical Chemistry, 73:14 (2001) 3247-3256.
  118. Z. Zhang*, H. Zhuo, S. Liu, and P.B. Harrington, Classification of cancer patients based on elemental contents of serums using bidirectional associative memory networks. Analytica Chimica Acta, 436:2 (2001) 281- 291.
  119. G. Chen and P.B. Harrington*, Real-Time Interactive Self-Modeling Mixture Analysis. Applied Spectroscopy, 55:5 (2001) 621-629.
  120. T.L. Buxton and P.B. Harrington*, Rapid Multivariate Curve Resolution Applied to Identification of Explosives by Ion Mobility Spectrometry. Analytica Chimica Acta, 434:2 (2001) 269-282.
  121. L.A. Shaw and P.B. Harrington*, Seeing through the Smoke with Dynamic Data Analysis: Detection of Methamphetamine in Forensic Samples Contaminated with Nicotine. Spectroscopy, 15:11 (2000) 40-45.
  122. P.B. Harrington*, A. Urbas, and C. Wan, Evaluation of Neural Network Models with Generalized Sensitivity Analysis. Analytical Chemistry, 72 (2000) 5004- 5013.
  123. P.B. Harrington*, A. Urbas, and P.J. Tandler, Two-Dimensional Correlation Analysis. Chemometrics and Intelligent Laboratory Systems, 50 (2000) 149-174.
  124. C. Wan and P.B. Harrington*, Screening GC-MS data for carbamate pesticides with temperature-constrained-cascade correlation neural networks. Analytica Chimica Acta, 408 (2000) 1-12.
  125. C. Wan and P.B. Harrington, Self-Configuring Radial Basis Function Neural Network for Chemical Pattern Recognition. Journal of Chemical Information and Computer Science, 39:6 (1999) 1049-1056.
  126. S.L. Slagel, P.B. Harrington*, and P. Schmittauer, Pulling the Plug on the Data Cable: Wireless transmission of chemical sensor data using a cordless phone. Spectroscopy, 14:10 (1999) 42-44, 66+.
  127. C. Cai and P.B. Harrington*, Prediction of Substructure and Toxicity of Pesticides with Temperature Constrained-Cascade Correlation Network from Low-Resolution Mass Spectra. Analytical Chemistry, 71 (1999) 4134-4141.
  128. C. Cai and P.B. Harrington*, Wavelet Transform Preprocessing for Temperature Constrained Cascade Correlation Neural Networks. Journal of Chemical Information and Computer Science, 39 (1999) 874-880.
  129. E.S. Reese and P.B. Harrington*, Analysis of Methamphetamine Hydrochloride by Thermal Desorption Ion Mobility Spectrometry and SIMPLISMA. Journal of Forensic Sciences, 44 (1999) 68-76.

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