Education

Biography

Dr. Nag is a graduate from California Institute of Technology. After postdoctoral training, she pursued research as a staff scientist at California Institute of Technology. She is starting her lab at the Clarkson School of Chemistry and Biochemistry at Clark University, in 2017.

Research Interest

• Inhibition of proteins involved in signal transduction pathways.
• Development of biomimetic metal- ligand frameworks for green energy processes such as water oxidation.
• Sensor development for phosphate containing small molecules.

Scientific Activities

HONORS AND AWARDS

• Recipient, American Chemical Society Dan Su Travel Award, 2016.
  Awarded to top four female applications for ACS Postdoc to Faculty (P2F) Workshop
• Travel award, American Peptide Society, 2015.
• National Finalist, NIH Director’s Early Independence Award (EIA/DP5), May 2014.
  Award supports exceptional young investigators who wish to pursue independent research      directly after completion of their terminal doctoral/research degree or clinical residency
• Nominee, Caltech for NIH Director’s Early Independence Award, December 2013. Two applicants chosen by Caltech as nominees.

Publications

1. Henning, R.K., Varghese, J.O., Das, S., Nag, A., Tang, G., Tang, K., Sutherland, A.M., Heath, J.R., Degradation of Akt Using Protein Catalyzed Capture Agents. Journal of Peptide Science, 2016, 22, 196-200. doi: 10.1002/psc.2858.
2. Das, S. #, Nag, A. #, Liang, J., Bunck, D. N., Umeda, A., Farrow, B., Coppock, M. B., Sarkes, D. A.,Finch, A. S., Agnew, H. D., Pitram, S., Heath, J. R., A General Synthetic Approach for Designing Epitope Targeted Macrocyclic Peptide Ligands. Angewandte Chemie International Edition 2015, 54(45), 13219–13224. doi:10.1002/anie.201505243 (# equal contribution)
3.  Farrow, B., Wong, M., Malette, J., Lai, B., Deyle, K. M., Das, S., Nag, A., Agnew, H. D. and Heath, J. R., Epitope Targeting of Tertiary Protein Structure Enables Target-Guided Synthesis of a Potent In-Cell Inhibitor of Botulinum Neurotoxin. Angewandte Chemie International Edition 2015, 54(24), 7114–7119. doi:10.1002/anie.201502451
4.  Deyle, K.M., Farrow, B., Hee, Y.Q., Work, J., Wong, M., Lai, B., Umeda, A., Millward, S.W., Nag, A., Das, S. and Heath, J.R. Protein-targeting strategy used to develop a selective inhibitor of the E17K point mutation in the PH Domain of Akt1. Nature Chemistry 2015, 7(5), 455-462. doi:10.1038/nchem.2223
5.  Nag, A., Das, S., Yu, M. B., Deyle, K. M., Millward, S. W. and Heath, J. R., A Chemical EpitopeTargeting Strategy for Protein Capture Agents: The Serine 474 Epitope of the Kinase Akt2. Angewandte Chemie International Edition 2013, 52(52), 13975– 3979.doi:10.1002/anie.201305882
6. Millward, S.W., Agnew, H.D., Lai, B., Lee, S.S., Lim, J., Nag, A., Pitram, S., Rohde, R. and Heath, J.R., In situ click chemistry: from small molecule discovery to synthetic antibodies. Integrative Biology 2013, 5 (1), 87-95. doi: 10.1039/c2ib20110k
7. Millward, S.W., Henning, R.K., Kwong, G.A., Pitram, S., Agnew, H.D., Deyle, K.M., Nag, A., Hein, J., Lee, S.S., Lim, J., Pfeilsticker, J.A., Sharpless, K.B., Heath, J.R. Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for Akt1. Journal of the American Chemical Society 2011, 133 (45), 18280-18288. doi:10.1021/ja2064389
8. Agnew, H.D., Rohde, R.D., Millward, S.W., Nag, A., Yeo, W.S., Hein, J.E., Pitram, S.M., Tariq, A.A., Burns, V.M., Krom, R.J. and Fokin, V.V. Sharpless, K.B., Heath, J.R., Iterative in situ click chemistry creates antibody-like protein-capture agents. Angewandte Chemie International Edition 2009, 48 (27), 4944-4948. doi:10.1002/anie.200900488
9. Nag, A., Chakraborty, D., Chandra, A., Effects of ion concentration on the hydrogen bonded structure of water in the vicinity of ions in aqueous NaCl solutions. Journal of Chemical Sciences 2008, 120(1), 71-77. doi:10.1007/s12039-008-0009-0.