alaa-a-a-aljabali
Alaa A A Aljabali, Ph.D
Assistant Professor of Nanoscience and Biotechnology

University of California San Diego Fellow in Responsible Conduct of Research
Assistant Dean (Quality Assurance)
Pharmacy Department, Yarmouk University, Irbid
Phone:  00962-797011031
E-mail: alaaj@yu.edu.jo

Education

  2015 - 2016 Fellowship in Responsible Conduct of Research,
University of California San Diego		   US
  2007 - 2011 Ph.D in Bionanoscience,
University of East Anglia- John Innes Centre 		  UK
  2006 - 2007 Masters of Research in Biotechnology,
University of Essex 		  UK
  1998 - 2002 B. Sc. Biological Sciences, with major in microbiology,
Yarmouk University, Irbid 		  JORDAN
  1992 General Certificate of Secondary Education, Tawjihi- Jordan   JORDAN

Biography

  • B.Sc. Yarmouk University- Biological science
  • Masters of Research- Essex University-UK- (working on breast cancer biomarkers for early detection and diagnosis)
  • PhD in Bionanoscience from John Innes Centre- UK (working on the development of plant viruses as tools and templates for nanomaterials synthesis
  • ​University of California San Diego Fellow in Responsible Conduct of Research
  • ​Assistant Dean (Quality Assurance)

Dr. Aljabali have published and co-authored more than 28 papers (one in Nature Communication and another in JACS) in peer-reviewed journal and 4 book chapters.

Dr. Aljabali Worked as:

  • a postdoctoral scientist at John Innes centre on the development of plant viruses as drug carriers and for drug targeting
  • Postdoctoral Research fellow at the department of the Cardiovascular medicine at the University of Oxford for 3 years working on the development of nanoparticles for medical applications
  • Assistant professor at the department of pharmacy Yarmouk university- Jordan

Dr. Aljabali’s lab mission is to push to new frontiers in biomaterials science and medicine through design, development, and testing of novel natural bio-inspired materials using plant virus-based scaffold. Leading a research laboratory interfacing of bio-inspired, molecular engineering approaches with medical research, technology development, and materials science. His group’s research focuses on the design of viral nanoparticles-based materials for applications in imaging, therapy, and drug targeting.


Research Interest

  • Nanomaterials development; naturally occurring nanoparticles/ synthetic, for application in Medicine
  • Nano-imaging
  • Synthesis, processing, and characterisation of novel nanomaterials for wide-range of applications
  • Bionanotechnology
  • Targeted drug delivery for cancer
  • Self-assembly, nano devices for biosensing applications

Scientific Activities

Honors And Awards

ACHIEVEMENTS

  • Awarded John Innes foundation first prize for excellence in science communication 2012
  • Best oral presentation in the 11th Eurasian Conference on the Chemical Sciences 2010
  • University of California San Diego fellow in Responsible Conduct of Research

PROFESSIONAL AFFILIATIONS

  • Royal Society of Chemistry (RSC) - Affiliate member
  • British Society for Nanomedicine
  • American Academy for the Advancement of Science (AAAS)
  • International Virtual Bionano Institute (iVBi)
  • Institute of nanotechnology

Publications

  1. Naveed Akbar, Janet E Digby, Thomas J Cahill, Abhijeet N Tavare, Sushant Saluja, Sam Dawkins, Laurienne Edgar, Nadia Rawlings, Klemen Ziberna, Eileen McNeill, Errin Johnson, Alaa A Aljabali, Rebecca A Dragovic, Mala Rohling, T Grant Belgard, David R Greav (2017) “A Endothelium-derived extracellular vesicles promote splenic monocyte mobilisation in myocardial infarction.” Heart 2017;103:A150
  2. Alaa A. A. Aljabali, Alberto Berardi, David J. Evans “Natures nanoparticles. Using viruses as nanomedicines” In Nanoparticles and nanostructured materials. Eksevuer S & T books. Volume II, Chapter XXX PP XXXX
  3. Naveed Akbar, Janet E Digby, Thomas J Cahill, Abhijeet N Tavare, Sushant Saluja, Sam Dawkins, Laurienne Edgar, Nadia Rawlings, Klemen Ziberna, Eileen McNeill, Errin Johnson, Alaa A Aljabali, Rebecca A Dragovic, Mala Rohling, T Grant Belgard, David R Greav (2017) “A Endothelium-derived extracellular vesicles promote splenic monocyte mobilisation in myocardial infarction.” Heart 2017;103:A150
  4. Rogen L. C. Leung, Matthew D. M. Robinson, Alaa A. A. Aljabali, Gogulan Karunanithy, Timothy D. W. Claridge, Andrew J. Baldwin and Benjamin G. Davis “Monitoring the Disassembly of Virus-like Particles by F19-NMR” Journal of ACS.
  5. AI Zoubi MS, Zavaglia K, Mazanti C, AI Hamad M, AI Batayneh K, Aliabali A A, Bevilacqua G (2017) “Polymorph isms and mutations in GSTP1, RAD51, XRCC1 and XRCC3 genes in breast cancer patients”, 2017, The international journal of Biological Markers, XXXXXXX
  6. Francisco Perez-Balderas, Sander I. van Kasteren, Alaa A. A. Aljabali, Andrew Jefferson, Sébastien Serres, Manuel Sarmiento Soto, Alexandre A. Khrapitchev, James R. Larkin, Claire Bristow, Seung Seo Lee, Guillaume Bort, Filippo De Simone, Robin P. Choudhury, Daniel C. Anthony, Nicola R. Sibson, Benjamin G. Davis (2017) “Covalent assembly of nanoparticles as a peptidase-degradable platform for molecular MRI” Nature Communications 8, 14254, 2017, pp1-10
  7. Mazhar Salim Al Zoubi, Katia Zavaglia, Chiara Mazanti, Mohammad Al Hamad, Khalid Al Batayneh, Alaa A. A. Aljabali, Generoso Bevilacqua (2017) “Polymorphisms and mutations in GSTP1, RAD51, XRCC1 and XRCC3 genes in breast cancer patients” The international journal of Biological Markers.
  8. Alaa A A Aljabali and David J Evans “Internal deposition of cobalt metal and iron oxide within CPMV eVLPs” In Virus-Derived Nanoparticles for Advanced Technologies Christina Wege and George Lomonossoff (eds), Humana Press, Chapter 16, pp xxxx
  9. Alaa A Aljabali (2016) “Recent Advances in Protein-Based Nano-Templates for Drug Delivery” Jordan Journal of Chemistry Vol. 11 No. 4, pp. 227-245
  10. Alaa A A Aljabali, David J Evans (2015) “Bionanomaterials from Plant Viruses” CRC Press Chapter 17 pages 263, 2015
  11. Mazhar Salim Al-Zoubi, Ibrahim Ali Al-Tayyar, Emad Hussein, Alaa Aljabali, Salih Khudairat  (2015) “Antimicrobial susceptibility pattern of Staphylococcus aureus isolated from clinical specimens in Northern area of Jordan” Iranian Journal of Microbiology, 7 (5), 265-272
  12. A. A. A. Aljabali, J. T. Chai, V. Thornton, J. E. Schneider, B. G. Davis, R. P. Choudhury (2014) “Multimeric microparticles of iron oxide (mMPIO) for dual modality molecular imaging with CT & MRI” (35) 284-285
  13. M. Jaafar, A. A. A. Aljabali, I. Berlanga, R. Mas-Ballesté, P. Saxena, S. Warren, G. P. Lomonossoff, D. J. Evans, and P. J. de Pablo (2014) “Structural Insights into Magnetic Clusters Grown Inside Virus Capsids” Applied Materials and Interfaces, 6(23) 20936–20942
  14. Frank Sainsbury, Pooja Saxena, Alaa A. A. Aljabali, Keith Saunders, David J Evans, George P Lomonossoff (2014) Genetic engineering and characterization of Cowpea Mosaic Virus empty virus-like particles. In Virus Hybrids as Nanomaterials: Methods and Protocols, Methods in Molecular Biology, 1108, B. Lin and B. Ratna (eds), Chapter 11, pp 139-153.
  15. Alaa A. A. Aljabali and David J. Evans (2014) Polyelectrolyte-modified Cowpea Mosaic Virus for the synthesis of gold nanoparticles. In Virus Hybrids as Nanomaterials: Methods and Protocols, Methods in Molecular Biology, 1108, B. Lin and B. Ratna (eds), Chapter 7, pp 97-103.
  16. Alaa A. A. Aljabali and David J. Evans (2014) Templated mineralization by charge-modified Cowpea Mosaic Virus. In Virus Hybrids as Nanomaterials: Methods and Protocols, Methods in Molecular Biology, 1108, B. Lin and B. Ratna (eds), Chapter 6, pp 89-95
  17. Caterina Arcangeli, Patrizia Circelli, Marcello Donini, Alaa A. A. Aljabali, Eugenio Benvenuto, George P Lomonossoff and Carla Marusic ( 2014) Journal of Biomolecular Structure & Dynamics (32) 4, 630-647.
  18. Alaa A. A. Aljabali, Sourabh Shukla, George P. Lomonossoff, Nicole F. Steinmetz and David J. Evans (2013) CPMV-DOX Delivers. Molecular Pharmaceutics, 10 (1), 3–10
  19. Alaa A. A. Aljabali, J. Elaine Barclay, Nicole F. Steinmetz, George P. Lomonossoff, and David J. Evans (2012) Controlled immobilisation of active enzymes on the Cowpea mosaic virus capsid. Nanoscale (4) 5640-5645
  20. Amy M. Wen, Sourabh Shukla, Pooja Saxena, Alaa A. A. Aljabali, Ibrahim Yildiz, Sourav Dey, Josh Mealy, Alice Yang, David J. Evans, George P. Lomonossoff, Nicole F. Steinmetz (2012) Interior engineering of a viral nanoparticle and its tumor homing properties. Biomacromolecules, 13 (12), 3990–4001.
  21. Alaa A. A. Aljabali, J. Elaine Barclay, Oscar Cespedes, Abdul Rashid, Sarah S. Staniland, George P. Lomonossoff and David J. Evans (2011) Charge modified Cowpea mosaic virus particles for templated miner Advanced Functional Materials (21) 4137-4142
  22. Frank Sainsbury, Keith Saunders, Alaa A. A. Aljabali, David J. Evans and George P. Lomonossoff (2011) Peptide-Controlled Access to the Interior Surface of Empty Virus Nanoparticles, ChemBioChem (12) 2435-2440.
  23. Alaa A. A. Aljabali, George P. Lomonossoff and David J. Evans (2011) CPMV-polyelectrolyte-templated gold nanoparticles,  Biomacromolecules (12) 7, 2723-2728.
  24. Alaa A. A. Aljabali, Sachin N. Shah, Richard Evans-Gowing, George P. Lomonossoff and David J. Evans (2011) Chemically-coupled-peptide-promoted virus nanoparticle template mineralization, Integrative Biology (3) 119-125. (Front Cover).
  25. Alaa A. A. Aljabali, J. Elaine Barclay George P. Lomonossoff and David J. Evans (2010) Virus templated metallic nanoparticles. Nanoscale (2) 2596-2600
  26. Alaa A. A. Aljabali, J. Elaine Barclay, Julea, N. Butt, George P. Lomonossoff and David J. Evans (2010) “Redox active ferrocene-modified Cowpea mosaic virus nanoparticles” Dalton Transactions, 7569-7574.
  27. Alaa A. A. Aljabali, Frank Sainsbury, George P. Lomonossoff and David J. Evans (2009) “Unmodified empty virus like particles can be loaded with metal and metal oxide” Small (6) 818-821.
  28. Sachin S. N. Shah, Nicole N. F. Steinmetz, Alaa A. A. Aljabali, George P. Lomonossoff and David J. Evans (2009) “Environmentally benign synthesis of virus-templated, monodisperse, iron-platinum nanoparticles” Dalton Transactions, 8479-8480.

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