Chaur-Dong Hsu, MD, MPH, FACOG
Keith A. Eddleman, PhD
Professor of Obstetrics Gynecology & Reproductive Science

Education

Undergraduate 1974-1978 University of North Carolina, Chapel Hill, North Carolina B.S., Zoology, 1978
Graduate 1981-1985 Bowman Gray School of Medicine, Wake Forest University Winston-Salem, North Carolina M.D., 1985
Postgraduate 1985-1989   1989-1991     1993-1996 George Washington University, Medical Center, Washington, D.C. Mount Sinai Medical Center, New York, New York                                The New York Hospital-Cornell Medical Center, New York, New York                                                            Allan B. Weingold, M.D., Chairman Department of Obstetrics and Gynecology, Residency in Obstetrics and Gynecology Richard L. Berkowitz, M.D. Chairman Department of Obstetrics, Gynecology & Reproductive Science
Fellowship in Maternal-Fetal Medicine Jessica G. Davis, M.D., Director Division of Human Genetics Fellowship in Clinical Genetics
 

Biography

Dr. Eddleman graduated from the Wake Forest University School of Medicine in 1985. He works and specializes in Obstetrics and Gynecology and Genetics, Medical. Dr. Eddleman is affiliated with Mount Sinai Medical Center and White Plains Hospital.

Research Interest

  • Clinical Genetics
  • Maternal & Fetal Medicine
  • Obstetrics & Gynecology

Professional Activities:

Academic
1989-1991 Mount Sinai School of Medicine, New York, New York              Clinical Instructor in Obstetrics, Gynecology & Reproductive Science
1991-1996 Cornell University School of Medicine                                                            Assistant Professor of Obstetrics and Gynecology
2001-2008 Mount Sinai School of Medicine     
New York, New York                                                          		Associate Professor of Obstetrics
Gynecology & Reproductive Science and Associate Professor of Human Genetics  
2008-Present Mount Sinai School of Medicine     
New York, New York                                                          		Professor of Obstetrics Gynecology & Reproductive Science and  Professor of Genetics and Genomic Sciences

Non-Academic
1978-1979 Teratology Laboratory, Research Triangle Institute, Research Triangle Park, NC  Research Associate
1979-1981 Clinical Research Laboratory, Environmental Protection Agency, Chapel Hill, NC Research Associate
1987-1988 Planned Parenthood League Bailey’s Crossroads, Virginia Clinical Director
1991-1996 The New York Hospital New York, New York Director of Prenatal Diagnosis
1996-2001 Mount Sinai Medical Cente                                Associate Director, Maternal-Fetal Medicine Fellowship Program
2001-2005 Mount Sinai Medical Center Board of Governors, Faculty Practice Associates
2001-2006 Mount Sinai Medical Center Director, Maternal-Fetal Medicine
Fellowship Program                                                                            
2000-2006 Mount Sinai Medical Center Director, Division of Maternal-Fetal Medicine
2006-present Mount Sinai Hospital Director of Obstetrics
2015-present The Mount Sinai Health System Director of Obstetrics
 
HONOURS AND AWARDS:
2000 Invited Speaker, Mount Sinai 2000 Update: Ultrasound, Women’s Imaging and
Mammography, New York, New York
2001 Visiting Professor, Department of Obstetrics and Gynecology, Stamford Hospital,
Stamford, CT
2004-present Oral examiner, American Board of Obstetrics and Gynecology
2005 Invited Speaker, Staten Island University Hospital
2006-2015 Listed in Castle Connolly Top Doctors New York Metro Area
2010-2015 Listed in Castle Connolly America’s Top Doctors
2006 Listed in Guide to America’s Top Obstetricians and Gynecologists
2009-2015 Listed in New York magazine “Best Doctors in New York” issue
2010       Listed in Marquis Who’s Who in America
2010 Listed in Cambridge Who’s Who Registry among Executives and Professionals in the Field of Research, Medicine and Healthcare
2011 Visiting Professor/Grand Rounds, University of North Carolina at Chapel Hill, Chapel Hill, NC
   

Publications

  1. Eddleman, KA, Levine, AB, Chitkara, U, Berkowitz, RL:  Reliability of lymphocyte counts in the antenatal diagnosis of congenital chylothorax. Obstet Gynecol 1991;78:530.
  2. Levine, AB, Eddleman, KA, Chitkara, U, Willner, JP, Vosatka, RJ, Berkowitz, RL: Myotonic dystrophy:  An often unsuspected cause of severe polyhydramnios, Prenatal Diagnosis 1991;11:111-15.
  3. Eddleman, KA, Lockwood, CJ, Berkowitz, GS, Berkowitz, RL:  The clinical significance and sonographic diagnosis of velamentous umbilical cord insertion.  Am J Perinat 1992;9:123-126.
  4. Lescale KB, Eddleman, KA, Chervenak, FA: Prenatal diagnosis: Structural abnormalities. Current Opinions in Obstetrics and Gynecology 1992;4:249-55.
  5. Durand, B, Eddleman, K, Migliaccio AR, Migliaccio, G, Adamson, JW: Long-term generation of CFC from CD34+ cord blood cells.  Leuk-Lymph 1993;11:263-73.
  6. Migliaccio, AR, Baiocci, M, Durand, B, Eddleman, K, Migliaccio, G, Adamson, J: Aspects of the biology of the neonatal hematopoietic stem cell. Stem Cells 1993;11(suppl. 2):56-64.
  7. Durand B, Migliaccio G, Yee NS, Eddleman K, Huima-Byron T, Migliaccio AR, Adamson JW.  Long-term generation of human mast cells in serum-free cultures of CD43+ cord blood cells stimulated with stem cell factor and interleukin-3. Blood 1994;84:3667-74.
  8. Migliaccio AR, Baiocchi M, Durand B, Eddleman K, Migliaccio G, Adamson JW. Stem cell factor and the amplification of progenitor cells from CD34+ cord blood cells.  Blood Cells 1994;20:129-38.
  9. Skupski D, Eddleman K, Zellers N, Ward B.  Rapid exclusion of chromosomal aneuploidies by fluorescence in situ hybridization prior to fetal surgery for obstructive uropathy - A case report.  Fetal Diagn Ther 1994;9:353-6.
  10. Lasker, MR, Eddleman, K, Toor, AH  Neonatal hepatitis and excessive hepatic iron deposition following intrauterine blood transfusion.  Am. J. Perinatol 1995;12:14-7.
  11. Eddleman KA, Chervenak FA, George-Siegel P, Baiocchi M, Migliaccio G, Migliaccio AR: Circulating hematopoietic stem cell populations in human fetuses: Implications for fetal gene therapy.  Fetal Diagn Ther 1996;11:231-240.
  12. Lescale KB, Inglis SR, Eddleman KA, Peeper EQ, Chervenak FA, McCullough LB.  Conflicts between physicians and patients in non-elective cesarean delivery:  Incidence and the adequacy of informed consent.  Am J Perinatol 1996;13:171-6.
  13. Lescale, KB, Eddleman, KA, Cines, DB, Samuels, P, Lesser, ML, McFarland, JG, Bussel, JB.  Antiplatelet antibody testing in thrombocytopenic pregnant women. Am J Obstet Gynecol 1996;174:1014-8.
  14. Migliaccio G, Baiocci M, Hamel N, Eddleman K, Migliaccio AR  Circulating              progenitor cells  in  human ontogenesis: Response  to growth factors  and replating potential.  J Hematother 1996;5:161-70.
  15. Berkowitz, RL, Stone, JL, Eddleman, KA One hundred consecutive cases of selective termination of an abnormal fetus in a multifetal gestation. Obstet Gynecol 1997;90:606-610.
  16. Hayward A, Ambruso C, Battaglia F, Donlon T, Eddleman K, Giller, R, Hobbins J, Hsia YE, Quinones R, Shpall R, Tractenberg E, Giardina P.  Microchimerism and tolerance following intrauterine transplantation and transfusion for alpha-thalassemia-1. Fetal Diagn Ther 1998;13:8-14.
  17. Stone J, Bianco A, Lockwood CJ, Berkowitz RL, Eddleman K.  Does the morbidity of twin gestations after 36 weeks increase with advanced gestational age? Perinat Neonat Med 1998;3:1-7.
  18. Wasserstein MP, Gaddipati S, Snyderman SE, Eddleman K, Desnick RJ, Sansaricq C.  Successful Pregnancy in Severe Methylmalonic Acidemia.  J Inher Metab Dis 1999;22:788-94.
  19. Eddleman KA, Stone JL, Lynch L, Berkowitz RL.  Chorionic villus sampling prior to multifetal pregnancy reduction.  Am J Obstet Gynecol 2000; 183:1078-81.
  20. Migliaccio AR, Migliaccio G, Hayward A, Eddleman K.  Circulating hematopoietic progenitor cells in a fetus with alpha-thalassemia:  Comparison with the cells circulating in normal and non-thalassemic anemic fetuses an implications for in utero transplantation.  Bone Marrow Transplantation 2002; 30:75-80.
  21. Eddleman KA, Stone JL, Lynch L, Berkowitz RL.  Selective termination (ST) of anomalous fetuses in multifetal pregnancies:  200 cases at a single center.  Am J Obstet Gynecol 2002; 187:1168-72.
  22. Stone JL, Eddleman KA, Lynch L, Berkowitz RL.  A single center experience with 1000 consecutive cases of multifetal pregnancy reduction (MPR).  Am J Obstet Gynecol 2002; 187:1163-7.
  23. Weiss JL, Malone FD, Emig D, Ball H, Nyberg DA, Comstock CH, Saade G, Eddleman K, Carter S, Craigo SD, Carr, SR, D’Alton ME, for the FASTER Research Consortium.  Obesity, obstetrical complications and cesarean delivery rate – a population based screening study.  Am J Obstet Gynecol 2004;190:1091-7.
  24. Dugoff L, Hobbins JC, Malone FD, Porter TF, Luthy D, Comstock CH, Saade G, Eddleman K, Merkatz I, Craigo SD, Timor-Tritsch IE, Carr SR, Wolfe HM, Tibbetts N, D’Alton ME. Quad screen as a predictor of adverse pregnancy outcome.  Obstet Gynecol 2005;106:260-7.
  25. Cleary-Goldman J, Malone FD, Vidaver J, Ball RH, Nyberg DA, Comstock CH, Saade GR, Eddleman KA, Gross SJ, Dugoff L, Timor-Tritsch IE, Craigo SD, Carr SR, Wolfe HM, D’Alton ME.  Impact of maternal age on obstetric outcome-a population based screening study.  Obstet Gynecol 2005;105:983-90.
  26. Shevell T, Malone F, Vidaver J, Porter T, Luthy D, Comstock C, Hankins G, Eddleman K, Dolan S, Dugoff L, Craigo S, Timor I, Carr S, Wolfe H, D’Alton M.  Assisted reproductive technology and pregnancy outcome-a population based screening study (the FASTER trial). Obstet Gynecol 2005;106:1039-45.
  27. Bush MC, Csaba A, Eddleman KA, Saphier CJ.  Is misoprostol safe for labor induction in twin gestations? J Matern Fetal Neonatal Med 2006;19:35-8.
  28. Lambert-Messerlian, G, Dugoff L, Vidaver J, Canick, J, Malone F, Porter F, Comstock C, Luthy D, Bukowski R, Eddleman K, Gross S, Craigo S, Timor I, Carr S, Wolfe H, D’Alton M. First and second trimester Down syndrome screening markers in pregnancies achieved through assisted reproductive technologies (ART):  A FASTER trial study.  Prenat Diagn 2006;26:672-8.
  29. Simpson LL, Malone FD, Bianchi DW, Ball RH, Nyberg DA, Comstock CH, Saade G, Eddleman K, Gross SJ, Dugoff L, Craigo SD, Timor-Tritsch IE, Carr SR, Wolfe HM, Tripp T, D’Alton ME.  Nuchal translucency and the risk of congenital heart disease.  Obstet Gynecol 2007;109:376-83.
  30. Eddleman K, Malone F, Sullivan L, Dukes K, Berkowitz R, Kharbutli Y, Porter T, Luthy D, Comstock C, Saade G, Klugman S, Dugoff L, Craigo S, Timor I, Carr S, Wolfe H, D’Alton M. Pregnancy loss rates after midtrimester amniocentesis.  Obstet Gynecol 2006;108:1067-72.
  31. Belogolovkin V, Engel SM, Ferrara L, Eddleman KA, Stone JL.  Does sonographic determination of placental location predict fetal birth weight in diamniotic-dichorionic twins? J Ultrasound Med 2007;26:187-91.
  32. Belogolovkin V, Eddleman K, Malone F, Sullivan L, Ball R, Nyberg D, Comstock C, Saade G, Gross S, Dugoff L, Craigo S, Timor-Tritsch I, Carr S, Wolfe H, D’Alton M.  The affect of low body mass index on the development of gestational hypertension and preeclampsia.  J Matern Fetal Neonatal Med 2007;20:509-13..
  33. Dolan S, Gross SJ, Merkatz IR, Faber V, Sullivan LM, Malone FD, Porter TF, Nyberg DA, Comstock CH, Hankins GDV, Eddleman K, Dugoff L, Craigo SD, Timor-Tritsch I, Carr SR, Wolfe HM, Bianchi DW, D’Alton ME.  The contribution of birth defects to prematurity and low birthweight in a population-based screening study. Obstet Gynecol 2007; 110:318-24.
  34. Belogolovkin V, Engel SM, Ferrara L, Eddleman KA, Stone JL.  Does sonographic determination of placental location predict fetal weight in diamniotic-dichorionic twins?  J Ultrasound Med. 2007 Feb;26(2):187-91.
  35. Stone J, Belogolovkin V, Matho A, Berkowitz RL, Moshier E, Eddleman K.  Evolving Trends in 2,000 Cases of Multifetal Pregnancy Reduction: a single center experience.  Am J Obstet Gynecol.  2007 Oct:197(4):394.e1-4..
  36. Dugoff L, Cuckle H, Hobbins JC, Malone FD, Belfort MA, Nyberg DA, Comstock CH, Saade GR, Eddleman KA, Dar P, Craigo SD, Timor-Tritsch IE, Carr SR, Wolfe HM, D’Alton ME for the FASTER Trial Research Consortium.  Prediction of patient-specific risk for fetal loss using maternal characteristics and first and second trimester maternal serum Down syndrome markers. Am J Obstet Gynecol 2008 Sep; 199:290.e1-6.
  37. Lee KA, Williams B, Roza K, Ferguson H, David K, Eddleman K, Stone J, Edelmann L, Richard G, Gelb G, Kornreich R. PTPN11 Analysis for the Prenatal Diagnosis of Noonan Syndrome in Fetuses with Abnormal Ultrasound Findings.  Clin Genet 2009;75:190-4.
  38. Bukowski R, Malone FD, Porter TF, Nyberg DA, Comstock CH, Hankins GDV, Eddleman K, Gross SJ, Dugoff L, Craigo SD, Timor-Tritsch IE, Carr SR, Wolfe HM, D’Alton ME. Preconceptional folate supplementation and the risk of spontaneous preterm birth. PLoS Med 2009 May 5;6(5):e1000061.
  39. Ferrara L, Gandhi M, Litton C, McClung EC, Jandl K, Moshier E, Eddleman K, Stone J.  Chorionic villus sampling and the risk of adverse outcome in patients undergoing multifetal pregnancy reduction.  Am J Obstet Gynecol 2008 Oct; 199:408.e1-4.
  40. Belogolovkin V, Ferrara L. Moshier E, Gandhi M, Eddleman K, Stone J.  Differences in fetal growth, discordancy and placental pathology in reduced versus nonreduced twins.  Am J Perinatol 2007 Nov; 24:575-9.
  41. Stone J, Ferrara L, Kamrath J, Getrajdman J, Berkowitz R, Moshier E, Eddleman K.  Contemporary outcomes with the latest 1000 cases of multifetal pregnancy reduction.  Am J Obstet Gynecol 2008;199:406.e1-4.
  42. Dugoff L, Cuckle H, Hobbins JC, Malone FD, Ball R, Nyberg D, Comstock CH, Saade G, Eddleman K, Gross S, Craigo S, Timor-Tritsch IE, Carr SR, Wolfe HM, Bianchi D, D’Alton ME. Assessment of risk for preeclampsia requiring delivery prior to 34 weeks gestation using maternal characteristics and serum markers.  Submitted to Obstet Gynecol 10/08.
  43. Aagaard-Tillery K, Malone FD, Nyberg DA, Porter TF, Cuckle HS, Fuchs KM, Sullivan L, Comstock CH, Saade GR, Eddleman K, Gross S, Dugoff L, Craigo SD, Timor IE, Carr SR, Wolfe HM, Bianchi DW, D’Alton ME for the FaSTER Research Consortium.  Role of seond trimester genetic sonography following Down syndrome screening.  Obstet Gynecol 2009;114:1189-96.
  44. Litton C, Stone J, Eddleman K, Lee MJ.  Non-invasive prenatal diagnosis:  The past, present and future. Mount Sinai Journal of Medicine 2009;76:521–528.
  45. Aagaard-Tillery KM, Porter TF, Malone FD, Nyberg DA, Collins J, Comstock CH, Hankins GD, Eddleman K, Dugoff L, Wolfe HM, D’Alton ME. Influence of maternal BMI on genetic sonography in the FaSTER trial.  Prenat Diagn 2010;30:14-22.
  46. Bianchi DW, Platt LD, Goldberg JD, et al. on behalf of the MatErnal Blood IS Source to Accurately diagnose fetal aneuploidy (MELISSA) Study group.  Genome-wide Fetal Aneuploidy Detection by Maternal Plasma DNA Sequencing.  Obstet Gynecol 2012;119:890-901.
  47. Moise KJ Jr, Boring NH, O’Shaughnessy R, Simpson LL, Wolfe H, Baxter JK, Polzin W, Eddleman KA, Hassan SS, Skupski D, McLennan G, Paladino T, Oeth P, and Bombard A. Circulating cell-free fetal DNA for the detection of fetal RHD status and sex using reflex fetal identifiers.  Prenatal Diagnosis 2013;33:95-101.
  48. Bigelow C, Moshier E, Eddleman K, Stone J.  Current trends and outcomes with selective termination.  Presented at SMFM 2012.  Submitted to Am J Obstet Gynecol.
  49. Barber JCK, Rosenfeld JA, Fouilds N, Laird S, Batemen M, Thomas NS, Baker S, Anilkumar A, Smith WE, Banks V, Ellingwood S, Kharbutli Y, Mehta, L, Eddleman KA, Marble M, Zambrano R, Crolla JA, Lamb AN.  8p23.1 duplication syndrome:  cardinal, confirmed and novel features in six further patients.  Am J Med Genet Part A 2013;161A:487-500.
  50. Bernstein PS, Nero D, Laurio A, Buckley A, Eddleman KA, Fisher N.  Improving physician documentation on labor and delivery through audit and feedback.  Submitted 6/12.
  51. Strong NK, Eddleman KA.  Diagnosis and management of neonatal alloimmune thrombocytopenia in pregnancy.  Clin Lab Med. 2013 Jun;33(2):311-25.
  52. Mella MT, Eddleman KA, Alloimmune Thrombocytopenia. International J Clin Transfusion Med 2015,3:29-40.
  53. Connolly KA, Eddleman KA. Amniocentesis:  a contemporary review. World J Obstet Gynecol 2016; 5(1):56-65.
  1. Stone JL, Eddleman KA, Berkowitz RL.  The echogenic intracardiac focus. Contemporary OB/GYN 1998; 43:73-78.
  2. Eddleman KA. Stem Cells:  What the obstetrician needs to know. Contemporary Ob/Gyn, 1998; 43:141-155.
  3. Eddleman KA, Stone JL, Berkowitz RL. Fetal echogenic bowel on ultrasound:  the bottom line.  Contemporary OB/GYN, 1998: 43: 53-67.
  4. Stone JL, Eddleman K, Patel S. Controversies in the intrapartum management of twin gestations.  Obstetrics and Gynecology Clinics of North America 1999;26:327-42.
  5. Gleason P, Eddleman K, Stone J.  Fetal Gastrointestinal Anomalies. Clinics in Perinatology 2000;4:901-20.
  6. Stone J, Eddleman K.  Multifetal Pregnancy Reduction. Curr Opin Obstet Gynecol 2000;12:491-96.
  7. Bush M, Eddleman K. Multifetal pregnancy reduction and selective termination.  In: Clinics in Perinatology 2003; 27(4):623-41.
  8. Rochon M, Eddleman K. Controversial Ultrasound Findings.  In: Obstetrics and Gynecology Clinics of North America 2004; 31(1):61-99.
  9. Gyamfi C, Eddleman K.  Alloimmune Thrombocytopenia.  In: Clin Obstet Gynecol 2005;48:897-909.
   
     
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