Research Assistant Professor
Department of Molecular and Medical Genetics
University of North Texas Health Science Center
Graduate School of Biomedical Sciences
USA
Education
| Institution And Location | Degree |
Completion Date |
Field Of Study |
| Harbin Institute of Technology | B.S. |
07/1996 | Hydraulic Transmission and Control |
| Harbin Institute of Technology | M.S. |
07/1998 | Flight Mechanics |
| Harbin Institute of Technology | Ph.D. |
08/2001 | General Mechanics |
| Tsinghua University | Postdoctoral |
09/2003 | Computer Science |
| University of California, San Diego | Postdoctoral |
07/2008 | Bioinformatics |
| Indiana University-Purdue University Indianapolis | Postdoctoral |
10/2011 | Bioinformatics |
Biography
Fan Zhang, Ph.D. is currently a research assistant professor in the Department of Molecular and Medical Genetics at the University of North Texas Health Science Center. He obtained his Ph.D. at the Harbin Institute of Technology in 2001 and completed his first postdoctoral work in the State Key Laboratory of Intelligent Technology and Systems, Tsinghua University from 2001 to 2003. He was an associate professor in the School of Biomedical Engineering at the Capital Medical University, China in 2005. He worked as a postdoctoral researcher in the Medical School of University of California at San Diego from 2006 to 2008 and in the School of Informatics at the Indiana University-Purdue University Indianapolis from 2008 to 2011. He worked as a Data Analyst at the Mount Sinai School of Medicine prior to joining UNT Health Science Center. He has contributed greatly to the understanding of molecular mechanisms of pathway biomarkers in cancer. He is involved in the development of research programs in integrative disease bioinformatics and computational discovery, verification and validation for disease biomarker.”
Research Interest
- Develop research programs in integrative disease bioinformatics and computational analysis for disease biomarker
- Develop algorithm, methods and tools in pathway analysis, data mining, machine learning and system biology
Professional Activities:
Positions and Honors
| 2005-2006 | Associate Professor, Biomedical Engineering School, Capital University of Medical Sciences, and director of biomedical informatics lab, Beijing, China |
| 2006-2008 | postdoc, Department of Radiology, University of California San Diego Medical School, San Diego, CA |
| 2008-2011 | postdoc, School of Informatics, Indiana University-Purdue University Indianapolis, Indianapolis, IN |
| 2011-2012 | data analyst, Department of Nephrology, Mount Sinai School of Medicine, NY |
| 2012-2015 | bioinformatician, Department of Academic and Institutional Resources and Technology, University of North Texas Health Science Center, Fort Worth, TX |
| 2015 - Present | Research Assistant Professor, Department of Molecular and Medical Genetics, University of North Texas Health Science Center, Fort Worth, TX |
Publications
- Fan Zhang, Mu Wang, Tran Michael, Renee Drabier. (2013) Novel Alternative Splicing Isoform Biomarkers Identification from High-Throughput Plasma Proteomics Profiling of Breast Cancer. BMC Systems Biology.
- Fan Zhang and Renee Drabier. (2013). SASD: the Synthetic Alternative Splicing Database for Identifying Novel Isoform from Proteomics. BMC Bioinformatics.
- Fan Zhang and Renee Drabier. (2012) IPAD: the Integrated Pathway Analysis Database for Systematic Enrichment Analysis. BMC Bioinformatics Vol. 13 Suppl 14.
- Ao Zhou, Fan Zhang, and Jake Y. Chen (2010) PEPPI: A Peptidomic Database of Human Protein Isoforms for Proteomics Experiments, BMC Bioinformatics, Vol. 11, Supplement 6, S7.
- Fan Zhang and Jake Y. Chen (2011) Computational Biomarker Discovery.
- Fan Zhang and Jake Chen (2010) Novel Protein Isoform Biomarkers Identification from Proteomes, BIBM workshop (DMBD 2010) December 18 - 21.
- S. E. O'Bryant, G. Xiao, F. Zhang, M. Edwards, D. C. German, X. Yin, et al. (2014) Validation of a serum screen for Alzheimer's disease across assay platforms, species, and tissues, J Alzheimers Dis, vol. 42, pp. 1325-35.
- D. German, P. O'Suilleabhain, F. Zhang, and S. O'Bryant (2014) ALZHEIMER'S DISEASE AND PARKINSON’S DISEASE: BLOOD BIOMARKER DIFFERENCES,Alzheimer's & Dementia, vol. 10, p. P348.
- O'Bryant SE, Xiao G, Edwards M, Devous M, Gupta VB, Martins R, Zhang F, Barber R, Texas Alzheimer's R, Care C: (2013) Biomarkers of Alzheimer's disease among Mexican Americans. Journal of Alzheimer's disease : JAD 2013, 34(4):841-849.
- Huebinger RM, Xiao G, Wilhelmsen KC, Diaz-Arrastia R, Zhang F, O'Bryant SE, Barber RC (2012): Comparison of protein concentrations in serum versus plasma from Alzheimer's patients. Advances in Alzheimer's Disease 2012, 1(3):51-58.
- Fan Zhang, Xiaogang Wu, and Jake Y. Chen (2013) Computational Biomarker Discovery.
- Fan Zhang, Tao Liu, Mu Wang, Renee Drabier. (2013) Dual-function biomarkers for detection of breast cancer and its cancer type: invasive versus non-invasive, BIBM 2013, Shanghai, China, December 18-21, 2013.
- Fan Zhang and Renee Drabier:(2012) Computational Discovery, Verification, and Validation of Functional Biomarkers. Royal Society of Chemistry of the United Kingdom.
- Fan Zhang and Renee Drabier. (2012) Recursive SVM Biomarker Selection for Early Detection of Breast Cancer in Peripheral Blood. BMC Medical Genomics Vol. 6 Suppl 1.
- Fan Zhang and Jake Y. Chen (2012) Breast cancer subtyping from plasma proteins. BMC Medical Genomics Vol. 6 Suppl 1.
- Fan Zhang and Jake Y. Chen (2010) Data Mining Methods for Biomarker Discovery. Bioinformatics for Omics data: Methods and Protocols.
- Fan Zhang and Renee Drabier (2014) Pathway-based biomarkers for breast cancer in proteomics. Cancer Bioinformatics.
- Fan Zhang, Youping Deng and Renee Drabier (2013) Multiple Biomarker Panels for Early Detection of Breast Cancer in Peripheral Blood. BioMed Research International.
- Fan Zhang, Jake Chen, Mu Wang, Renee Drabier: (2013) A Neural Network Approach to Multi-biomarker Panel Discovery by High-Throughput Plasma Proteomics Profiling of Breast Cancer. GLBIO 2013, PITTSBURGH, May 14-16, 2013 BMC Proceedings.
- Fan Zhang and Renee Drabier (2012) IPAD: the Integrated Pathway Analysis Database for Systematic Enrichment Analysis. BMC Bioinformatics Vol. 13 Suppl 14.
- Fan Zhang and Jake Y Chen (2010) Discovery of Pathway Biomarkers from Coupled Proteomics and Systems Biology Methods. BMC Genomics, Vol. 11, Supplement 2, S12
- Fan Zhang, Chen JY (2009)A Neural Network Approach to Multi-biomarker Panel Development Based on LC/MS/MS Proteomics Profiles: A Case Study in Breast Cancer, The 22nd IEEE International Symposium on Computer-Based Medical Systems. Aug 2-4.
