Papadopoulou Lefkothea
Manuela Martins-Green, Ph.D
Professor of Cell Biology
  • Department of Cell Biology and Neuroscience
    University of California
    California, USA
    Phone: (951) 827-2585



B.S., Biology

University of Lisbon, Portugal

M.S., Plant Pathology

University of California, Riverside

Ph.D., Zoology

University of California, Davis



Manuela Martins-Green is Professor of Cell Biology in the Department of Cell Biology and Neuroscience at the University of California, Riverside. Professor Martins-Green came to the US from Portugal on a Fulbright Fellowship and received a PhD in Zoology with emphasis in Developmental Biology from the University of California, Davis Dec 1987. She held a postdoctoral fellowship at the Lawrence Berkeley National Laboratory and a National Research Service Award, and was Adjunct Assistant Professor at Rockefeller University before joining the UC Riverside faculty in 1993.

Research Interest

Research and Teaching: She is an internationally recognized researcher in wound healing and tissue engineering and pioneered the role of chemokines in wound healing and angiogenesis. More recently, her research program has expanded to development of ways to improve burn healing using insulin dressings, has developed a murine model for study of the basic cell and molecular mechanisms of chronic wounds, studies on the effects of tobacco toxin on healing and studies the effects of pomegranate juice components on metastasis of prostate cancer.


Scientific Activities:

Honors and Awards


  • Fulbright Travel Grant for graduate study in USA.
  • Departmental Fellowship, Department of Plant Pathology, UC Riverside.
  • Elected to Phi Kappa Phi.
  • NIH Traineeship, Cellular and Molecular Training Grant, UC Davis.
  • Regents Fellowship, UC Davis.
  • Graduate Research Award, UC Davis.
  • Jastro-Shields Research Award, UC Davis.


  • NRSA Postdoctoral Fellowship (NIH), Lawrence Berkeley Laboratory.



Associate Editor, Journal of Molecular Oncology


Regents Faculty Fellowship, UC Riverside


Department of Defense Breast Cancer Rev Panel, Immunology Study Section #2


Speaker for the Annual Wound Healing Society Meeting


Nominee, Academic Achievement Jr. Award, Women in Cell Biology, ASCB.


Member, WHS Membership Committee


Invited Speaker, Keystone Meeting on Chemokines and their Receptors.


Faculty Development Award, UC Riverside


Visiting Scientist, Lab. of Molecular Immunoreg., Natl. Cancer Inst., Frederick, MD.


Nominee for the Outstanding Teaching Award at UCR


Selected to organize a pre-meeting sub-group symposium on “The Cell Biology of Chemokines in Host Defense, Wound Healing and Disease” for the annual meeting of the American Society for Cell Biology (ASCB)


Invited to participate as a chemokine expert on a workshop sponsored by the Radiation Research Program, Division of Cancer Treatment and Diagnosis, NCI.


Member, ASCB Standing Committee, Women in Cell Biology (WICB) and representative of this committee on the education committee


Speaker, Angiogenesis Minisymposium, ASCB 42nd Annual meeting


Abstract selected for the ASCB Press Book (1stTime)


Member, UCR Committee on Committees/Chair 2003-04 (Elected by faculty)


Major speaker at the Gordon Conference in Vascular Biology, Ventura CA


Award from CORE 21, The Technology Forum Series at UC Riverside, for Contrib. to Research Leadership and Technical Innovation to our Larger Society


Member of the Advisory Board for the Calif Annual Tissue Engineering Meeting


Abstract selected for the ASCB Press Book (2nd Time)


Chair of the UCR Division of the Academic Senate (Elected by faculty)


External Associate, Vanderbilt Institute of Integrative Biosystems Research and  Education (VIIBRE), Vanderbilt University, Nashville, Tennesse


Nominated by UCR for the Independent Citizens Oversite Committee (ICOC) of the California Institute of Regenerative Medicine


Member, Editorial Board of “Current Stem Cell Research & Therapy”


Abstract selected for the ASCB Press Book (3rd Time)


Visiting Scientist, Stanford University


Program Co-chair for the Wound Healing Society annual meeting


UCR Distinguished Service Award


UCR Innovative Teaching Award


Guest Professor, Northwest University, Xian, China


Chair of the Awards Committee for the Wound Healing Society


Editor of the Wound Healing Society Newsletter

2010- present

Member, Inaugural Board of Directors of the UC School of Global Health


Elected Fellow of the American Association for the Advancement of Science (AAAS)


Abstract selected for the ASCB Press Book (4th Time)


Member, External Advisory Board to evaluate junior Portuguese scientists funded by the International Program “Ciencia 2007” (a program funded by the European Union)


Member, Chancellor’s Council on Campus Climate, Communication &Inclusion


Affiliated Professor of the Faculty of Medicine, University of Porto, Portugal


Member, UC President’s Faculty Diversity Working Group of the Advisory Council on Climate, Culture, Communication and Inclusion (CCC&I)


Chair, UC-wide Senate Committee on Affirmative Action and Diversity (UCAAD) and Member, Academic Council of the Statewide Senate of the Univ of California


Member, Advisory Board for the “UCR ADVANCE”NSF Grant for Women of Color


Member, Board of Directors of the Wound Healing Society


Abstract selected for the ASCB Press Book (5th Time)


Member of the WRR strategic task force


Member of the WHS annual meeting strategic task force


Nominated for Distinguished Teaching Award



  1. Borges, M.L. and M. Martins (1972). Etiology of tobacco reversion.Agronomia Lusitana,33: 443-453 (in Portuguese).
  2. Ascencao, L.M., M.L. Borges and M. Martins (1974). Ultrastructural and physiological changes in Nicotiana tabacum L. leaves infected with Tobacco Vein Mosiac Virus. Agronomia Lusitana 35: 232-241 (in Portuguese).
  3. Antunes, T., M.L. Borges and M. Martins (1974). Cell ultrastructure of Vicia fabe L. infected with Bread Bean Mosaic Virus, Agronomia Lusitana 35: 465-477. (in Portuguese).
  4. Portela-Gomes, G., M. Martins and J. Pinto Correia (1974). Ultrastructural changes of Jejunal epithelial cells in liver cirrhosis, Scand. J. Gastroent.9: 657-663.
  5. Martins-Green, M. (1978). A simple procedure to obtain thick flat cornea sections for optical microscopy, Stain Technology53: 296-298.
  6. Roth, A.R., J.L. Keltner, W.G. Ellis and M. Martins-Green (1979). Virus-simulating structures in the optic nerve head in Creutzfeldt-Jakob disease, Amer. J. Ophthalmology 87: 827-833.
  7. Martins-Green, M. and A.R. Roth (1982). Tubular aggregates in the non-pigmented epi-thelial cells of the ciliary body of the Rhesus Monkey.J. Ultrastruct. Res. 80:206-213.
  8. Martins-Green, M. and C.A. Erickson (1986). The development of neural tube basal lamina during neurulation and neural crest cell emigration in the trunk of the mouse embryo.J. Embryol. Exp. Morph. 98: 219-236.
  9. Martins-Green, M. (1987). Ultrastructural and immunolabeling studies of the neural crest: Processes leading to neural crest cell emigration. PhD Dissertation, Univ. Calif., Davis, 194pp.
  10. Martins-Green, M. and C.A. Erickson (1987). Basal lamina is not a barrier to neural crest cell emigration: Documentation by TEM and by immunofluorescent and immunogold labeling. Development 101: 517-533.
  11. Martins-Green, M. and K.T. Tokuyasu (1988). A pre-embedding immunolabeling technique for basal lamina and extracellular matrix molecules.J. Histochem. and Cytochem. 36: 453-458.
  12. Martins-Green, M. (1988). Origin of the dorsal surface of the neural tube by progressive delamination of epidermal ectoderm and neuroepithelium: Implications for neurulation and neural tube defects. Development 103: 687-706.
  13. Martins-Green, M. and C.A. Erickson (1988). Patterns of cholinesterase staining during neural crest cell morphogenesis in mouse and chick embryos. J Exp. Zool. 247:62-68.
  14. Martins-Green, M. (1990). Transmission electron microscopy and immunolabeling of tissues for light and electron microscopy. In The Postimplantation Mammalian Embryo: A Practical Approach, A. Copp, ed, pp.127-154, IRL Press, Oxford, UK.
  15. Martins-Green, M. and M.J. Bissell (1990). Localization of 9E3/CEF4 in avian tissues: Expression is absent in RSV-induced tumors but is stimulated by injury. J. Cell Biol. 110: 581-595. (photo on journal cover)
  16. Stoker, A., C. Streuli, M. Martins-Green and M.J. Bissell (1990).Designer microenvironments for the analysis of cell and tissue function.Current Opinion in Cell Biol. 22: 864-874.
  17. Martins-Green, M., C. Tilley, R. Schwarz, C. Hatier, and M.J. Bissell (1991). Wound-factor-induced and cell cycle phase-dependent expression of 9E3/CEF4, the avian gro gene. Cell Regulation2: 739-752. (photo on journal cover)
  18. Martins-Green, M., A. Aotaki-Keen, L. Hjelmeland and M.J. Bissell. (1992) The 9E3 protein: Immunolocalization in vivo and evidence for multiple forms in culture. J. Cell Science 101: 701-707.
  19. Martins-Green, M., N. Boudreau, and M.J. Bissell (1994). Inflammation is responsible for the development of wound tumors in RSV-infected newly-hatched chicks.  Cancer Res. 54:4334-4341.
  20. Martins-Green, M. and M.J. Bissell (1995). Cell-extracellular matrix interactions in development.Sems. in Dev. Biol. 6:149-159.
  21. Fang, K., M.Martins-Green, L. T. Williams and H. Hanafusa (1996). Molecular cloning of chicken protein tyrosine phosphatase and its expression in the central nervous system. Molecular Brain Research37: 1-14. (photo on journal cover)
  22. Martins-Green, M., M. Stoeckle, S. Wimberly, A. Hampe and H. Hanafusa (1996). The 9E3/CEF4 cytokine: kinetics of secretion, processing by plasmin, and interaction with extracellular matrix. Cytokine8: 448-459.
  23. Martins-Green, M. (1997) Dynamics of Cell-ECM interactions with implications for tissue engineering. In Principles of Tissue Engineering. Ed. R.P. Lanza, W.L. Chick and R. Langer. R.G. Landes Co. pp 25-48 (invited review).
  24. Martins-Green, M. and H. Hanafusa (1997). The 9E3/CEF4 gene and its product the chicken Chemotactic and Angiogenic Factor (cCAF): potential roles in wound healing and tumor development. Cytokines and Growth Factor Rev. 8(3): 219-230.
  25. Vaingankar, S. and M. Martins-Green (1998). Thrombin activation of the 9E3/CEF4 chemokine involves tyrosine kinases including c-src and the EGF receptor. J Biol Chem. 273:5226-5234.
  26. Martins-Green, M., and J.E. Feugate (1998). The 9E3/CEF4 gene product is a chemotactic and angiogenic factor that can initiate the wound healing cascade in vivo.Cytokine 10:522-535.
  27. Martins-Green M., and T. Kelly (1998). The chicken chemotactic and angiogenic factor (cCAF): Its Angiogenic properties reside in the C-terminus of the molecule. Cytokine 10:819-829.
  28. Li, QJ., S. Vaingankar, H. M. Green, and M.Martins-Green (1999). Activation of the 9E3/cCAF chemokine by phorbol esters occurs via multiple signal transduction pathways that converge in MEK1/ERK2 and activate the Elk1 transcription factor. J. Biol. Chem.274:15454-15465.
  29. Martins-Green, M. (2000) Dynamics of cell-ECM interactions with implications for tissue engineering. In Principles of Tissue Engineering.2nd Edition, Eds. R.P. Lanza, W.L. Chick and R. Langer. R.G. Landes Co. (invited). pp33-55.
  30. Melkonian, G., C. Li, W. Zheng, P. Talbot and M. Martins-Green (2000). Normal patterns of angiogenesis and extracellular matrix deposition in chick chorioallantoic membranes are disrupted by mainstream and side stream cigarette smoke. Toxicology and Applied Pharmacology163:26-37.
  31. Martins-Green, M. (2000). The 9E3/cCAF chemokine. Chapter 10012 in "A Compendium of Cytokines and Other Mediators of Host Defense" (eds. J. Oppenheim, S. Durum), Academic Press Ltd.
  32. Martins-Green, M., J. L. Bixby, T. Yamamoto, T. Graf and M. Sudol (2000). Tissue specific expression of Yrk kinase: implications for differentiation and inflammation. International J. of Biochem.and Cell Biol. 32:351-364.
  33. Li, QJ., S. Lu, R. Ye and M. Martins-Green (2000). Isolation and characterization of a novel CXC chemokine receptor gene.Gene 257:307-317.
  34. Li, QJ., S. Vaingankar, F. Sladek, M. Martins-Green (2000). Novel nuclear target for thrombin: activation of the Elk1 transcription factor leads to chemokine gene expression. Blood 96:3692-3702.
  35. Liang, TS, JK Hartt, S. Lu, M. Martins-Green, J-L Gao, PM Murphy (2001). Cloning, mRNA distribution, and functional expression of an avian counterpart of the chemokine receptor/HIV coreceptor CXCR4.J. Leukocyte Biol.69:297-305.
  36. Martins-Green, M. (2001). The chicken chemotactic and angiogenic factor, a CXC chemokine.Special Issue on Angiogenesis, J. Laurent and L. Claesson-Welsh (eds).International J. of Biochem.and Cell Biol.33: 427-432.
  37. Martins-Green, M. (2001). The 9E3/cCAF chemokine. Chapter 10012 in "A Compendium of Cytokines and Other Mediators of Host Defense" (eds. J. Oppenheim, S. Durum), Academic Press Ltd. 2nd update.
  38. Feugate, J.E., QJ Li, L Wong, Martins-Green, M. (2002). The CXC chemokine cCAF stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure in vivo. Journal of Cell Biology156: 161-172.
  39. Martins-Green, M. (2002). Functions of the chicken IL-8 (cCAF) in wound healing. Wounds14:187-198 (Invited Review).
  40. Feugate, J.E., Wong, L, Li, QJ and Martins-Green, M. (2002). The CXC chemokine cCAF stimulates precocious deposition of ECM molecules by wound fibroblasts, accelerating development of granulation tissue. BMC Cell Biology 3:1-15.
  41. Salcedo, R., M. Martins-Green, B. Gertz, J. J. Oppenheim, and W. J. Murphy (2002).Combined administration of human IL-8 and EGFR antibodies results in synergistic anti-tumor effects on human breast carcinoma xenografts.Clin. Cancer Res.8: 2655-2665.
  42. Li, Q-J., Yang, S-H., Maeda, Y.,. Sladek, F.M., Sharrocks, A. D. and Martins-Green, M. (2003). Map kinase phosphorylation-dependent activation of Elk-1 leads to activation of the coactivator p300. EMBO Journal22: 1-11.
  43. Salcedo, R., X. Zhang, H. A. Young, M. Nelson, K. Wasserman, W.-H. Ma, M. Martins-Green, W. J. Murphy,and J. J. Oppenheim (2003). Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells. Blood102:1966-1977.
  44. Altstein, M., QJ Li, M. Martins-Green. (2003) Tissue specific expression of the Pyrokinin/PBAN receptors. Peptides, 24:1335-1347.
  45. Wong, L., HM Green, JE Feugate, M Yadav, EA Nothnagel, M. Martins-Green (2004). Effects of "second-hand" smoke on structure        and function of fibroblasts, cells that are critical for tissue repair and remodeling. BMC Cell Biology5:1-14. With press release.
  46. Wong, L. and M. Martins-Green (2004). “Firsthand” cigarette smoke alters fibroblasts migration and survival: Implications for impaired Healing. Wound Repair and Regeneration 12:471-84.
  47. Zhou, Rui-Hai*, Min Yao*, Tzong-Shyuan Lee, Yi Zhu, Manuela Martins-Green, and John Y-J. Shyy (2004).Vascular Endothelial Growth Factor Activation ofSerol Regulatory Element Binding Protein: A Potential Role in Angiogenesis. Circ Res. 95:471-8. Epub 2004 Jul 22. PMID: 15271857.
  48. Li, QJ, M. Yao, W. Wong, V. Parpura, M. Martins-Green. (2004). The N- and C-terminal peptides of hIL8/CXCL8 are ligands for hCXCR1 and hCXCR2. FASEB Epub Feb 6.
  49. Li, QJ, M. Yao, W. Wong, V. Parpura, M. Martins-Green. (2004). The N- and C terminal peptides of hIL8/CXCL8 are ligands for hCXCR1 and hCXCR2. FASEB J. 18:776-8. Three page summary + unique figure
  50. Martins-Green, M. Q-J Li and Min Yao (2005). A new generation organ culture arising from cross-talk between multiple primary human cell types. The FASEB Journal express article 10.1096/fj.04-1725fje. Published online 2004 December 9.
  51. Martins-Green, M. Q-J Li and Min Yao (2005). A new generation organ culture arising from cross-talk between multiple primary human cell types. FASEB J.19:222-224. Three page summary + unique figure.
  52. Li, Q.U., Yao, M., Dueck, M.L., Parpura, V., Martins-Green, M. 2005. cCXCR1 is a Receptor for cIL8 (9E3/cCAF) and its N- and C-Terminal Peptides, and is also Activated by hIL8 (CXCL8). J. Leukocyte Biol, 7: 1-14.
  53. Ueda, Eric, Ugur Ozerdem, Yen-Hao Chen, Min Yao, Huiqin Sun, Manuela Martins-Green, Paolo Bartolini and Ameae M. Walker (2006). A molecular mimic demonstrates that phosphorylated human prolactin is a potent anti-angiogenic hormone. Endocr. Relat. Cancer13:95-111.
  54. Yao,Min, Rui-Hai Zhou, Melissa Petreaca, John Shyyand Manuela Martins-Green (2006). “Signal Transduction Pathways Stimulated by Different Types of Angiogenic Factors Converge in Activation of SREBPs and RhoA”.J. Leukocyte Biology80: 608-620. Epub Jul 18.
  55. Dueck-Petreaca, Melissa and Manuela Martins-Green (2006). "Biologic and Molecular Basis of Regenerative Medicine: Cell-Extracellular Matrix Interactions" in Principles of Regenerative Medicine,eds. A. Atala, R. Lanza, James Thomson, Robert Nerem.
  56. Dueck-Petreaca, Melissa and Manuela Martins-Green (2006). "Cell-Extracellular Matrix Interactions with implications for Tissue engineering" in Principles of Tissue engineering, 3rd edition, edited by Robert Lanza, R. Langer and J. Vacanti.
  57. Yuan, Hongwei, Lina Wong, Monideepa Bhattacharya, Matthias Schneider,Robert E. Pitasand Manuela Martins-Green (2007). Second-Hand Smoke Effects on Biological Processes Important in Atherogenesis.BMC Cardiovascular Disorders, 7: 1-16.
  58. Zheng, Lei, Christian Lytle, Ching-ni Njauw, Miriam Altstein and Manuela Martins-Green (2007). Cloning and Characterization of the Pheromone Biosynthesis Activating Neuropeptide Receptor Gene in Spodoptera littoralis Larvae.Gene, doi:10.1016/j.gene.2006.12.025.
  59. Zheng, Lei and Manuela Martins-Green (2007). Molecular Mechanisms of Thrombin-Induced Interleukin-8 Expression in THP-1-derived and primary human Macrophages. J Leukoc. Biol82:619-629.
  60. Zheng, L., Njauw, C.N., Manuela Martins-Green. 2007. An hCXCR1 transgenic mouse model containing a conditional color-switching system for imaging of hCXCL8/IL-8 functions in vivo.J Leukoc. Biol.82:1-10.[Epub ahead of print].
  61. Patreaca, M., Yao, M., Liu, Y., DeFea, K., Martins-Green, M. 2007. Transactivation of Vascular Endothelial Growth Factor Receptor-2 (VEGFR2) by Interleukin-8 (IL-8/CXCL8) Is Required For IL-8-Induced Endothelial Permeability. Molecular Biology of the Cell 18:5014–5023.
  62. Huynh N, Mallik B, Zhang L, Martins-Green M, Morikis D. 2008. Computational studies of CXCR1, the receptor of IL-8/CXCL8, using molecular dynamics and electrostatics. Biopolymers.89:52-61.
  63. Dueck-Petreaca, Melissa and Manuela Martins-Green 2007. "Dynamics of Cell-ECM Interactions" in Principles of Tissue Engineering, 3rd edition, Chapter 7, edited by Robert Lanza, Robert Langer and Joseph Vacanti. (Refereed, Non-Electronic, Invited).
  64. Dueck-Petreaca, Melissa and Manuela Martins-Green2008. "Biologic and Molecular Basis of Regenerative Medicine: Cell-Extracellular Matrix Interactions in Repair and Regeneration" in Principles of Regenerative Medicine, Chapter 5, pp 66-99. Edited by Anthony Atala, Robert Lanza, James Thomson, Robert Nerem. Publisher, Elsevier (Refereed, Non-Electronic, Invited).
  65. Njauw, Ching-Ni, Hongwei Yuan 1, Lei Zheng, Min Yao, Manuela Martins-Green(2008). Origin of periendothelial cells in microvessels derived from human microvascular endothelial cells. The International Journal of Biochemistry & Cell Biology 40:710–720.Available online at
  66. Zheng, Lei, Ching-Ni Njauw, Manuela Martins-Green (2008).A one-plasmid conditional color-switching transgenic system for multimodal bioimaging.Transgenic Res. 17: 741-747.
  67. Martins-Green,Manuela, Melissa Petreaca,and Min Yao (2008). An assay system for in vitro detection of permeability in human “endothelium”.Methods in Enzymology443::137-53
  68. Petreaca, M.L., Yao, M., and M. Martins-Green (2008). VEGF promotes macrophage apoptosis through stimulation of Tumor Necrosis Factor superfamily member 14 (tnfsf14/light). Wound Repair and Regeneration16:602-614.
  69. Liu, Yan, Melissa Petreaca, and Manuela Martins-Green (2008). Cell and Molecular Mechanisms of Insulin-Induced Angiogenesis.J. Cell and Molec.Medicine12: 1-13.
  70. Liu, Yan, Melissa Petreaca, Min Yao, Manuela Martins-Green (2009). Insulin accelerates re-epithelialization during wound healing through integration of multiple aspects of keratinocyte behavior. BMC Cell Biology, 10:1-15.
  71. Ma, G., and Manuela Martins-Green. (2009). Second-hand Cigarette Smoke Inhibits Wound Healing of the Cornea by Stimulating Inflammation and Delaying Corneal Re-epithelialization.Wound Repair and Regeneration, 17:387-396.
  72. Hongwei Yuan, John Y.-J Shyy, Manuela Martins-Green (2009). Second-Hand Smoke Stimulates Lipid Accumulation in the Liver by Modulating AMPK and SREBP-1.HEPT 51:535-547.With extensive editorial comments by:
  73. Editorial:Ariane Mallat and Sophie Lotersztajn (2009). Cigarette smoke exposure: A novel cofactor of NAFLD progression? JHEPT51(3):430-432.
  74. Martins-Green, M, Y. Vodovotz, P. Liu (2010). Systems Biology Applied to Wound Healing. Wound Repair and Regeneration18:1-2
  75. Yuan, H.,Chongze Ma,Lisa Moinet,Noboru Sato and Manuela Martins-Green(2010). Thymosin 4 in combination with anti-inflammatory agents reverses “second-hand” cigarette smoke-induced impairment of cornea wound healing. Investigative Ophthalmology & Visual Science51:1-12.
  76. Martins-Green, M. and Petreaca, M. (2010). A Family of Small Cytokines Called Chemokines is Important in Regulation of Wound Repair. Advances in Wound Care1: Section 5- Inflammation, Chapter 28. Editor, Chandan K. Sen. ISBN13: 978-1-934854-01-3 ISBN10: 1-934854-01-8.
  77. Dueck-Petreaca, M. and M. Martins-Green (2010). "Biologic and Molecular Basis of Regenerative Medicine: Cell-Extracellular Matrix Interactions in Repair and Regeneration" Foundations of Regenerative Medicine, Part II. Chapter 5, pp 66-69, edited by Anthony Atala, Robert Lanza, James Thomson, Robert Nerem, Acad. Press.
  78. Hrynyk, M., M. Martins-Green, A. E. Barron and R. J. Neufeld (2010). PLGA microspheres as a vehicle for sustained topical delivery of bioactive human insulin. International Journal of Pharmaceutics 398:146–154
  79. Wang, Lei, Andre Alcon, Hongwei Yuan, Jing Li and M. Martins-Green (2011). Cellular and Molecular Mechanisms of Pomegranate Juice-Induced Anti-Metastatic Effect on Prostate Cancer Cells. Integrative Biology3: 742-754
  80. Matt, G. E. Penelope J. E. Quintana, Hugo Destaillats, Lara A. Gundel,
  81. Mohamad Sleiman, Brett C. Singer, Peyton Jacob III, Neal Benowitz, Jonathan P. Winickoff, Virender Rehan, Prue Talbot, Suzaynn Schick, Jonathan Samet, Yinsheng Wang, Bo Hang, Manuela Martins-Green, James F. Pankow, Melbourne F. Hovell (2011). Thirdhand Tobacco Smoke: Emerging Evidence and Arguments for a Multidisciplinary Research Agenda. Environmental Health Perspectives, doi: 10.1289/ehp.1103500.
  82. Martins-Green, M. (2012). The Yin and Yang of Integrin Function in Re-epithelialization During Wound Healing. In Advances in Wound Care: Volume 1:1-7.
  83. Petreaca M. L., Danh Do, Sandeep Dhall, Darcie McLelland, Avo Serafino,Julia Lyubovitsky, Neal Schiller, and M. Martins-Green (2012). Deletion of a Tumor Necrosis Superfamily Gene in Mice Leads to Impaired Healing that Mimics Chronic Wounds in Humans. Wound Repair and Regeneration20: 353-366.
  84. Hrynyk, Michael,Manuela Martins-Green, Annelise E. Barron and Ronald J. Neufeld (2012). Alginate-PEG Sponge Architecture and Its Influence on Next-Generation Bioactive Insulin Releasing Dressings.Biomacromolecules14:1478-85.
  85. Huang, Zhouchun, Li, Xiang,Martins-Green, Manuela, Liu, Yuxin (2012) Microfabrication of Cylindrical Microfluidic Channel Networks for Microvascular Research. Lab on a Chip. Biomed Microdevices
  86. Wang, Lei, Jeffrey Ho, Carlotta Glackinand M. Martins-Green (2012). Specific Pomegranate Juice Components as Potential Inhibitors of Prostate Cancer Metastasis.Translational Oncology5: 1-12.
  87. Petreaca, Melissa and Manuela Martins-Green 2012. "Dynamics of Cell-ECM Interactions" in Principles of Tissue Engineering, 4th edition, Chapter 7, edited by Robert Lanza, Robert Langer and Joseph Vacanti. (Refereed, Non-Electronic, Invited).
  88. Rocha, Ana,Lei Wang, Manuela Penichet, Manuela Martins-Green .(2012). Pomegranate Juice and Specific Components Inhibit Cell and Molecular Processes Critical for Metastasis of Breast Cancer Cells. BREA,Published on line Oct 12th, 2012. DOI 10.1007/s10549-012-2264-5.
  89. Zhouchun Huang, Xiang Li, Manuela Martins-Green, Yuxin Liu (2012). Microfabrication of cylindrical microfluidic channel networks for microvascular research. Biomedical Devices BioMEMS and Biomedical Nanotechnology.
  90. Martins-Green, M. and Petreaca, M. (2013) Chemokines: chemokines and their receptors are key players in the orchestra that regulates wound healing. Advances in Wound Care vol1: 217-223.
  91. Li, X. Samantha Mearns, Manuela Martins-Green, Yuxin Liu (2013). Procedure for the Development of Multi-Branching and Multi-Depth Microvessels-on-a-Chip.JOVE 4:1-9.
  92. Wang Lei, Martins-Green M. The potential of pomegranate and its components for prevention and treatment of breast cancer.Agro Food Ind Hi Tech. 2013; 24(5):58-61.
  93. Richmond, Nicholas A., Jeffrey Davidson, Manuel Martins-Green, Chandan Sen, Marjana Tomic-Canic, Sonia A. Lamel, Alejandra C. Vivas, Liza R. Braun, Robert S. Kirsner (2013).NIH Funded Research for Cutaneous Wounds in 2012.WRR in Press.
  94. M. Martins-Green, N. Adhami, M. Frankos, M. Valdez, B. Goodwin, J. Lyubovitsky, S. Dhall, M. Garcia, I. Egiebor, B. Martinez, H.W. Green, C. Havel, L. Yu, S. Liles, G, Matt,            H. Destaillats, M. Sleiman, L.A. Gundel, N. Benowitz, P. Jacob III, M. Hovell, J.P. Winickoff, M. Curras-Collazo (2014). Cigarette smoke toxins deposited on surfaces: Implications for human health. PLOS ONE, 9, Issue 1, 12 pages:
  95. Wang, Lei, Wenfang Li, Muqing Lin, Monika Garcia, David Mulholland, Michael Lillyand Manuela Martins-Green (2014). Luteolin, Ellagic Acid and Punicic Acid are Natural Products that Inhibit Prostate Cancer Metastasis. Carcinogenesis 35, 2321-2330.
  96. Wang, Leiand Manuela Martins-Green (2014). Pomegranate and its Components as Alternative Treatment for Prostate Cancer.Int. J. Mol. Sci., 15(9), 14949-14966; doi:10.3390/ijms150914949
  97. Baquerizo Nole, Katherine L., Elizabeth Yim, Freya Van Driessche, Jeffrey M. Davidson, Manuela Martins-Green, Chandan K. Sen, Marjana Tomic-Canic, Robert S. Kirsner (2014). Wound research funding from alternative sources of federal funds in 2012. WRR 22:295-300.
  98. Dhall, S., Monica Garcia, Dayanjan Shanaka Wijesinghe,Angelika Brandon, Rakesh Pravindrachandra Patel, and Manuela Martins-Green (2014). A novel model of chronic wounds in a mouse model of impaired healing: Importance of redox imbalance and biofilm-forming bacteria for establishment of chronicity. PLOS ONE 9, Issue 10: 17 pages,
  99. Dhall, S., D. C. Do,M. Garcia,J. Kim,S. H. Mirebrahim,J.Lyubovitsky,S. Lonardi,E. A. Nothnagel,N. Schiller,and M. Martins-Green .Generating and Reversing Chronic Wounds In Diabetic Mice By Manipulating Wound Redox Parameters.Journal of Diabetes Research
Vol: 2014, Article ID 562625, 18 pages.
  100. Karim, Z.A., F. Z. Alshbool, H. P. Vemana, N. Adhami, S. Dhall, O. A. Lin1, E. V. P. Espinosa, M. Martins-Green2 and F. T. Khasawneh (2015). Third Hand Smoke: Impact on Hemostasis and Thrombogenesis. J Cardiovasc Pharmacol. In Press J Cardiovasc Pharmacol. Apr 7.
  101. Dhall, S. , Dayanjan Shanaka Wijesinghe, Zubair A Karim, Anthony Castro, Hari Priya Vemana, Fadi T. Khasawneh, Charles E. Chalfant and Manuela Martins-Green(2015). Arachidonic acid-derived signaling lipids and functions in impaired healing. WRR 13p.
  102. Silva, J.P., S. Dhall, M. Garcia, A. Chan, C. Costa, M. Gama, M. Martins-Green(2015).
  103. Improved burn wound healing by the antimicrobial peptide LLKKK18 released from conjugates with dextrin embedded in a carbopol gel. Acta Biomaterialia. 14p.
  104. Dhall,S., J. P. Silva, Y. Liu, M. Hrynyk, M. Garcia, R. Neufeld, and M. Martins-Green(2015). Sustained release of insulin from alginate dressings enhances healing of burns. Clinical Science. 15p.
  105. Shelley R. Starck, Jordan Tsai, Keling Chen, Michael Shodiya, Allen Wang, Kinnosuke Yahiro, Manuela Martins-Green, Nilabh Shastri, Peter Walter (2015).A non-canonical uORF sustains BiP expression during the Integrated Stress Response. Science, In Press
  106. Ren, W., Ji, A., Karmash, O., Carter, D.G., Martins-Green, M., Ai H. A Membrane-Activatable Near-Infrared Fluorescent Probe with Ultra-Photostability for Imaging Mitochondrial Membrane Potential.
  107. Adhami, Neema, Shelley R. Starck, Cristina Flores, Manuela Martins Green (2016).A health threat to bystanders living in the homes of smokers: How smoke toxins deposited on surfaces can cause insulin resistance.
  108. Sandeep Dhall, Zubair A Karim, Fadi T. Khasawneh, and Manuela Martins-Green(2016).
  109. Platelet Hyperactivity in Impaired Healing.Advances in Wound Care.In Press.
  110. Omran Karmachand Manuela Martins-Green(2016). Prostate Cancer and the Therapeutic Potential of Pomegranate. Chapter in a book entitled: Complementary and Alternative Medicines in Prostate Cancer: A Comprehensive Approach. Invited review. In Press
  111. Dhall, S., R. Alamat, A. Castro, A. H Sarker, J-H. Mao, A. Chan, B. Hang, andM. Martins-Green (2016). Tobacco Toxins Deposited on Surfaces (Third Hand Smoke) Impair Wound Healing.  Clinical Sciences 130, 1269-1284.
  112. Flores C, Adhami N, Martins-Green M (2016) THS Toxins Induce Hepatic Steatosis by Altering Oxidative Stress and SIRT1 Levels. J Clin Toxicol 6: 318.
  113. Peyton Jacob III, Neal L. Benowitz,Hugo Destaillats, Lara Gundel, Bo Hang, Manuela Martins-Green, Georg E. Matt, Penelope JE. Quintana,Jonathan M. Samet,Suzaynn F. Schick, Prue Talbot, Noel J. Aquilina, Melbourne F. Hovell, Jian-Hua Mao, Todd P. Whitehead (2016). Thirdhand Smoke: New Evidence, Challenges, and Future Directions. Chemical Research in Toxicology. Invited review In Press.
  114. Petreaca M. M.Martins-Green (2017). Cell-ECM Interactions in Repair and Regeneration. Principles of Regenerative Medicine, 3rd Ed. Invited review.
  115. Liu, Y., Cheng X-L, Martins-Green M. Insulin antagonizes thrombin-induced micro vessel leakage. Under revision.
  116. Karmash, O,Lei Wang, Sandeep Dahll, Yuxin Liu and Manuela Martins-Green. Successful Passaging of Cultured Primary Human Hepatocytes. Submitted.



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