Education

Biography

Prof. Antonio M. Rabasco is Full Professor of Pharmaceutical Technology at the University of Seville since 1993. He received his Ph. D. degree in Pharmaceutical Technology from Seville University, Spain. He was the Head of the Department of Pharmacy and Pharmaceutical Technology at the University of Seville from 1997 to 2012. He is currently the Director of the Chair Avenzoar (University of Seville) in order to apply the new technologies of information and communication to pharmaceutical care.

Research Interest

Study of innovative formulations aimed to the production of drug delivery systems such as colloidal systems, liposomes, nanoparticles and microbeads containing drug – cyclodextrin complexes.

Scientific Activities

Employment History

Professional Activities

Membership in Scientific/Professional Organizations

• 2017 - Member of the Editorial Board of the Journal of Biomedical Research and Practice
• 2017 - President of the Alumni Association of the Faculty of Pharmacy of Seville 2017 - Member of the Board of Directors of Pharmacists without Borders of Spain
• 2014 - Member of the Academic Council of the Ibero-American Academy of Pharmacy
• 2014 - Member of the Editorial Committee of the Ars Pharmaceutica Magazine 2014 - Evaluator of the FONCYT Agency of Argentina
• 2012 - Autonomous Member of Industry of the Andalusian Council of Pharmaceutical Colleges
• 2011 - Member of the Editorial Board of The Scientific World Journal
• 2010 - 2011 Member of the working group of the International Pharmaceutical Federation (FIP) that elaborated the document "FIP reference paper on the effective utilization of pharmacists in improving maternal, newborn and child health (MNCH)"

Honors and Awards

• Prof. Rabasco is a life member of scientific academies.
• He also played instrumental role in different prestigious internal collaborative research projects with European and American countries.
• He was Chair of the Spanish Portuguese Local Chapter of the Controlled Release Society

Publications

1. Alginate/chitosan particulate systems for sodium diclofenac release ML González-Rodrıguez, MA Holgado, C Sanchez-Lafuente, ...International Journal of Pharmaceutics 232 (1), 225-234
2. Effect of cholesterol and ethanol on dermal delivery from DPPC liposomes JM Lopez-Pinto, ML Gonzalez-Rodriguez, AM Rabasco. International journal of pharmaceutics 298 (1), 1-12
3. Preparation and characterisation of liposomes encapsulating ketoprofen–cyclodextrin complexes for transdermal drug delivery. F Maestrelli, ML González-Rodríguez, AM Rabasco, P Mura.International journal of pharmaceutics 298 (1), 55-67
4. Development, characterization and in vivo evaluation of benzocaine-loaded liposomes P Mura, F Maestrelli, ML González-Rodríguez, I Michelacci, C Ghelardini, ...European Journal of Pharmaceutics and Biopharmaceutics 67 (1), 86-95
5. Effect of preparation technique on the properties of liposomes encapsulating ketoprofen–cyclodextrin complexes aimed for transdermal delivery. F Maestrelli, ML González-Rodríguez, AM Rabasco, P Mura. International journal of pharmaceutics 312 (1), 53-60
6. Lipids in pharmaceutical and cosmetic preparations. AMR Alvarez, MLG Rodríguez. Fats and oils 51 (1-2), 74-96
7. Diclofenac salts, II. Solid dispersions in PEG6000 and Gelucire 50/13. A Fini, JR Moyano, JM Ginés, JI Perez-Martinez, AM Rabasco. European journal of pharmaceutics and biopharmaceutics 60 (1), 99-111
8. Development of sustained release matrix tablets of didanosine containing methacrylic and ethylcellulose polymers C Sánchez-Lafuente, MT Faucci, M Fernández-Arévalo, ...International journal of pharmaceutics 234 (1), 213-221
9. Effects of the host cavity size and the preparation method on the physicochemical properties of ibuproxam-cyclodextrin systems.P Mura, E Adragna, AM Rabasco, JR Moyano, JI Perez-Martinez, ... Drug development and industrial pharmacy 25 (3), 279-287
10. Influence of the preparation method of solid dispersions on their dissolution rate: study of triamterene-D-mannitol system. MJ Arias, JM Gines, JR Moyano, JI Perez-Martinez, AM Rabasco. International journal of pharmaceutics 123 (1), 25-31
11. Percolation theory: application to the study of the release behaviour from inert matrix systems. I Caraballo, M Fernández-Arévalo, MA Holgado, AM Rabasco. International journal of pharmaceutics 96 (1-3), 175-181
12. Didanosine extended-release matrix tablets: optimization of formulation variables using statistical experimental design.C Sánchez-Lafuente, S Furlanetto, M Fernández-Arévalo, ...International journal of pharmaceutics 237 (1), 107-118
13. Characterization of ibuproxam binary and ternary dispersions with hydrophilic carriers.M Cirri, P Mura, AM Rabasco, JM Gines, JR Moyano, ...Drug development and industrial pharmacy 30 (1), 65-74
14. Development of enteric-coated pectin-based matrix tablets for colonic delivery of theophylline P Mura, F Maestrelli, M Cirri, M Luisa González Rodríguez, ...Journal of drug targeting 11 (6), 365-371
15. Application of statistical experimental design to study the formulation variables influencing the coating process of lidocaine liposomes. ML Gonzalez-Rodriguez, LB Barros, J Palma, PL Gonzalez-Rodriguez, ...International journal of pharmaceutics 337 (1), 336-345
16. Relationship between drug percolation threshold and particle size in matrix tablets.I Caraballo, M Millan, AM Rabasco. Pharmaceutical research 13 (3), 387-390
17. Study of the dissolution characteristics of oxazepam via complexation with β-cyclodextrin. JR Moyano, JM Ginés, MJ Arias, AM Rabasco.International Journal of Pharmaceutics 114 (1), 95-102
18. Effect of preparation technique on the properties and in vivo efficacy of benzocaine-loaded ethosomes. F Maestrelli, G Capasso, ML González-Rodríguez, AM Rabasco, ...Journal of liposome research 19 (4), 253-260
19. The role of the drug/excipient particle size ratio in the percolation model for tablets. M Millán, I Caraballo, AM Rabasco. Pharmaceutical research 15 (2), 216-220
20. Charged liposomes as carriers to enhance the permeation through the skin ML Gonzalez-Rodriguez, AM Rabasco.Expert opinion on drug delivery 8 (7), 857-871
21. New “drug-in cyclodextrin-in deformable liposomes” formulations to improve the therapeutic efficacy of local anaesthetics. F Maestrelli, ML González-Rodríguez, AM Rabasco, C Ghelardini, P Mura. International journal of pharmaceutics 395 (1), 222-231
22. In vitro release of sodium diclofenac from a central core matrix tablet aimed for colonic drug delivery ML González-Rodríguez, F Maestrelli, P Mura, AM Rabasco. European journal of pharmaceutical sciences 20 (1), 125-131
23. Characterization and dissolution properties of ketoprofen in binary and ternary solid dispersions with polyethylene glycol and surfactants. P Mura, JR Moyano, ML González-Rodríguez, AM Rabasco-Alvarez, ...Drug development and industrial pharmacy 31 (4-5), 425-434
24. Evaluation of Eudragit® RS-PO and Ethocel® 100 matrices for the controlled release of lobenzarit disodium A Boza, I Caraballo, J Alvarez-Fuentes, AM Rabasco Drug development and industrial pharmacy 25 (2), 229-233
25. Nuclear magnetic resonance investigations of the inclusion complexation of gliclazide with β‐cyclodextrin.JR Moyano, MJ Arias-Blanco, JM Gines, AM Rabasco, JI Pérez-Martínez, ... Journal of pharmaceutical sciences 86 (1), 72-75
26. Dissolution properties and in vivo behaviour of triamterene in solid dispersions with polyethylene glycols. MJ Arias, JM Gines, JR Moyano, AM Rabasco Swiss Pharmaceutica Journal 71 (4), 229-235
27. Dissolution Behavior of Oxazepam in Presence of Cyclodextrins: Evaluation of Oxazepam-Dimeb Binary Systemxs .JR Moyano, MJ Arias, JM Gines, JI Perez, AM Rabasco. Drug development and industrial pharmacy 23 (4), 379-385
28. Dissolution rate of diazepam from polyethylene glycol 6000 solid dispersions. AM Rabasco, JM Ginés, M Fernández-Arévalo, MA Holgado. International journal of pharmaceutics 67 (2), 201-205
29. Elaboration and thermal study of interactions between cinnarizine and gelucire® 5310 physical mixtures and solid dispersions. JM Gines, MD Veiga, MJ Arias, AM Rabasco. International journal of pharmaceutics 126 (1-2), 287-291
    
    Estimation of the percolation thresholds in dextromethorphan hydrobromide matrices. LM Melgoza, AM Rabasco, H Sandoval, I Caraballo. European journal of pharmaceutical sciences 12 (4), 453-459
30. Design of controlled release inert matrices of naltrexone hydrochloride based on percolation concepts. I Caraballo, LM Melgoza, J Alvarez-Fuentes, MC Soriano, AM Rabasco. International journal of pharmaceutics 181 (1), 23-30
31. The application of solid dispersion technique with D-mannitol to the improvement in oral absorption of triamterene. MJ Arias, JM Gines, JR Moyano, AM Rabasco. Journal of drug targeting 2 (1), 45-51
32. Influence of diluents and manufacturing method on the in vitro dissolution of carteolol hydrochloride matrix tablets. MA Holgado, I Caraballo, J Alvarez-Fuentes, MJ Fernández-Hervás, ...International journal of pharmaceutics 118 (2), 151-160
33. Communications simultaneous HPLC determination of some drugs commonly used in cold medications: dextromethorphan, dephenhydramine, phenylephrine, phenylpropanolamine and pseudoephedrine. I Caraballo, M Fernandez-Arevalo, MA Holgado, J Alvarez-Fuentes, ...Drug development and industrial pharmacy 21 (5), 605-613
34. Physical characterization of carteolol: Eudragit® L binding interaction. MA Holgado, M Fernandez-Arevalo, J Alvarez-Fuentes, I Caraballo, ...International journal of pharmaceutics 114 (1), 13-21
35. Study of the release mechanism of carteolol inert matrix tablets on the basis of percolation theory. I Caraballo, M Fernández-Arévalo, MA Holgado, AM Rabasco, ...International journal of pharmaceutics 109 (3), 229-236
36. Positively and negatively charged liposomes as carriers for transdermal delivery of sumatriptan: in vitro characterization.S Villasmil-Sánchez, W Drhimeur, SCS Ospino, AM Rabasco Alvarez, ...Drug development and industrial pharmacy 36 (6), 666-675
37. Development and validation of a reverse-phase liquid chromatographic method for the assay of lidocaine hydrochloride in alginate-Gantrez® microspheres .S Salas, B Talero, AM Rabasco, ML González-Rodríguez. Journal of pharmaceutical and biomedical analysis 47 (3), 501-507
38. Study of percolation thresholds in ternary tablets. I Caraballo, M Fernández-Arévalo, M Millán, AM Rabasco, ...International journal of pharmaceutics 139 (1-2), 177-186
39. Characterization study of a diclofenac salt by means of SEM and fractal analysis. MA Holgado, MJ Fernandez-Hervas, AM Rabasco, A Fini International journal of pharmaceutics 120 (2), 157-167
40. Study of morphine hydrochloride percolation threshold in Eudragit® RS–PM matrices. LM Melgoza, I Caraballo, J Alvarez-Fuentes, M Millán, AM Rabasco. International journal of pharmaceutics 170 (2), 169-177
41. Zero-order release periods in inert matrices. Influence of the distance to the percolation threshold. I Caraballo, M Millán, AM Rabasco, H Leuenberger. Acta Pharmaceutica Switzerland, 71 (5), 335-339
42. Factors governing the dissolution of diclofenac salts A Fini, G Fazio, MJF Hervás, MA Holgado, AM Rabasco. European journal of pharmaceutical sciences 4 (4), 231-238