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Case Report
Esophageal Angioectasia with Stigmata of Recent Bleeding within Barrett’s Esophagus

  S Sansone*      S Beg       K Ragunath       A Parra-Blanco   

NIHR Nottingham Digestive Diseases Biomedical Research Unit, Queens Medical Centre, Nottingham University Hospitals NHS Trust, UK

*Corresponding author: Stefano Sansone, Trauma NIHR Nottingham Digestive Diseases Biomedical Research Unit, Queen’s Medical Centre, Derby Road NG7 2UH, Nottingham, UK, Tel: 00447514116136; E-mail:

A 65-year-old lady presented with coffee ground vomiting, haemoglobin drop from 8.0 to 6.5 g/dL, urea rise from 2.8 to 9.6mmol and hypotension. Her medical history included a recent left total hip replacement for a vascular necrosis, alcoholic liver disease and Barrett’s esophagus for which she was undergoing 2-yearly surveillance. Her most recent Esophagogastroduodenoscopy (EGD) had been performed three months earlier. This confirmed the presence of 5cm hiatus hernia and long segment of Barrett’s esophagus, histology confirmed intestinal metaplasia with no evidence of dysplasia.

After supportive measures, including a 2-unit blood transfusion an EGD was performed. This confirmed the presence of Barrett’s esophagus (C10 M11), within which was a 5 mm vascular ectasia at 30 cm from the incisors, at the 5 O’clock position. A white nipple was noted on top of the ectasia, likely to represent a sign of recent bleeding. The EGD was completed, with no alternate sources of bleeding identified.

The area of ectasia within the Barrett’s segment was lifted with a submucosal injection of 3mL epinephrine (1:10’000) and treated with Argon Plasma Coagulation (APC). There were no complications, with no clinical or biochemical evidence of further bleeding within 30 days post therapy.

Angioectasias are uncommon cause of gastrointestinal bleeding [1]. However, there is just one previous case of esophageal angioectasia described in the literature to date [2]. This case similarly occurred within a segment of Barrett’s esophagus and was successfully treated with APC. Here we describe the first case of an esophageal angioectasia which appears to be responsible for significant blood loss, with stigmata of recent bleeding. We opted to manage this lesion with methods previously used for treatment of vascular ectasias [3]. However, in order to be cautious and prevent the risk of deep thermal injury we previously lifted the area with diluted epinephrine, which could also help in bleeding haemostasis [4,5].


  1. Foutch PG (1993) Angiodysplasia of the Gastrointestinal Tract. Am J Gastroenterol 88: 807-818. [Ref.]
  2. Khanna S, Arora AS, Topazian MD (2011) Esophageal vascular ectasia. Endoscopy 43: E281. [Ref.]
  3. Rosenfeld G, Enns R (2009) Argon photocoagulation in the treatment of gastric antral vascular ectasia and radiation proctitis. Can J Gastroenterol 23: 801-804. [Ref.]
  4. Hwang JH, Fisher DA, Ben-Menachem T, Chandrasekhara V, Chathadi K, et al. (2012) The role of endoscopy in the management of acute non-variceal upper GI bleeding.. Gastrointest Endosc 75: 1132- 1138. [Ref.]
  5. Manner H, Neugebauer A, Scharpf M, Braun k, May A, et al. (2014) The tissue effect of argon-plasma coagulation with prior submucosal injection (Hybrid-APC) versus standard APC: A randomized ex-vivo study vivo study. United European Gastroenterol J 2: 383-390. [Ref.]

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Article Information

Article Type: Case Report

Citation: Sansone S, Beg S, Ragunath K, ParraBlanco A (2017) Esophageal Angioectasia with Stigmata of Recent Bleeding within Barrett’s Esophagus. Clin Res Open Access 3(1): doi

Copyright: © 2017 Sansone S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history: 

  • Received date: 13 Mar 2017

  • Accepted date: 27 Mar 2017

  • Published date: 31 Mar 2017