kalra, jawahar (jay)
Roger S. Riley, MD, PhD
Professor and Co-Director

Department of Pathology
VCU Medical Center
Virginia Commonwealth University
Richmond, VA 23298
Phone: 804-828-0338, Email: rsriley@hsc.vcu.edu


1971 Frostburg State University B.S., Biology
1975 West Virginia University School of Medicine Ph.D. Biochemistry
1978 West Virginia University School of Medicine  M.D.



Roger S. Riley, MD, PhD, FCAP is a professor of pathology at the Virginia Commonwealth University. He is currently Co-Director of the Hematology Laboratory, Director of the Hemostasis Laboratory, and Program Director for the Hematopathology Fellowship Program. He received his PhD in biochemistry and medical degree from West Virginia University. Prior to joining the Department of Pathology at VCU in 1997, he served as Director of the Immunopathology, Histocompatibility, and Flow Cytometry Laboratories at West Virginia University and Texas Tech University, and Director of Hematopathology at West Virginia University. At East Carolina University, he served as Pathologist-In-Charge of Molecular Immunopathology and Histocompatibility Testing and director of the Research Core Flow Cytometry Laboratory. He is a former member of the Immunopathology Council of the American Society for Clinical Pathology (ASCP) who served as the primary or participating faculty in numerous workshops at national ASCP meetings since 1987. He is currently a member of the Resident In Service Examination (RISE) Committee of the ASCP and the editorial board of the Journal of Clinical Laboratory Analysis.

Research Interest

His current research interests include the diagnosis and pathogenesis of diseases of hemostasis.


Scientific Activities:

Special Awards and Other Honors:
  1. CRC Achievement Award in Chemistry, Frostburg State College, 1968
  2. Senior Honor Award in Biological Sciences, Frostburg State College, 1971
  3. Scholar of the New York Life Insurance Company, 1975-1978
  4. Medical Student Summer Research Fellow, West Virginia University School of Medicine, 1975
  5. Nominee, National Board of Medical Examiners, 1991
  6. Faculty Mentor in Instructional Technology, Virginia Commonwealth University, 1998
  7. Recipient, Saul Kay Award, Department of Pathology, VCU Medical Center, Richmond, VA, 2004



  1. Shipe, T., Moore, B.L., and Riley, R.S. Glanzmann thrombocythemia, ASCP Case Reports (CHKS-2013-10-0080-H), 2014.
  2. Sayeed, S., Williams, L.A., Riley, R.S., Roseff, S.D. Catastrophic antiphospholipid syndrome - Distinguishing features for diagnosis and treatment. ASCP Check Sample Program, 2013.
  3.  Riley, R.S., Hollenstead, S.C., and Mongia, S. Bone marrow contamination of cerebral spinal fluid. ASCP Clinical Pathology CheckPath Program (CheckPath CP Case 0038), 2011.
  4. Riley, R.S. Williams, D., Ross, M., Zhao, S., Chesney, A., Clark, B.D., and Ben-Ezra, J.M. Bone marrow aspirate and biopsy: A pathologist’s perspective. II. Interpretation of the bone marrow aspirate and biopsy. J. Clin. Lab. Anal. 23 : 259–307, 2009.
  5. Williams, D.C., Massey, G.V., Russell, E.C., Riley, R.S., Ben-Ezra, J. Translocation positive acute myeloid leukemia associated with valproic acid therapy in a 2 year old child. Pediatr. Blood Cancer 50(3): 641-643, 2008.
  6. Chang, S.H. Park, H.K., Eryilmaz, R., Bu, D., Stone, J.J., Massey, D., Riley, R.S., Fisher, R.A..: A new alloantigen-independent control for chronic allograft nephropathy rat models. J. Surg. Res. 128(1):50-54, 2005.
  7. Riley, R.S., Idowu, M., Chesney, A., Zhao, S., McCarty, J., Lamb, L.S., and Ben-Ezra, J.M.: Hematologic aspects of myeloabalative therapy and bone marrow transplantation, J. Clin. Lab. Anal. 19:47-79, 2005.
  8. Riley, R.S., Tidwell, A.R., Zhao, S., McPherson, R.A., Bode, A.P., and Carr, M.E.: A review inhemostasis testing, Part 2. Advance for Administrators of the Laboratory, 13(10):56-62, 2004.
  9. Riley, R.S., Tidwell, A.R., Zhao, S., McPherson, R.A., Bode, A.P., and Carr, M.E.: A review in hemostasis testing, Part 1. Advance for Administrators of the Laboratory, 13(9): 80-90, 2004.
  10. Riley, R.S.: Drawing and modeling: Essential parts of medical education. Chem News, 14.2:12-13, 2004.
  11. Riley, R.S., Idowu, M., Chesney, A., Clark, B.D., Massey, D. Ben-Ezra, J.M.: Perspectives in pathology. The value of the bone marrow aspirate, biopsy: Part 2. Advance for Administrators of the Laboratory., 13 (4), 22, 2004.
  12. Riley, R.S., Idowu, M., Chesney, A., Clark, B.D., Massey, D. Ben-Ezra, J.M.: Perspectives in pathology. The value of the bone marrow aspirate, biopsy: Part 2. Advance for Administrators of the Laboratory., 13 (3), 14, 2004.
  13. Riley, R.S., Idowu, M., Chesney, A., Clark, B.D., Massey, D. Ben-Ezra, J.M.: Perspectives in pathology. The value of the bone marrow aspirate, biopsy: Part 1. Advance for Administrators of the Laboratory., 13 (2): 20, 2004.
  14. Riley, R.S., Ben-Ezra, J.M., Massey, D., Slyter, R.L., Romagnoli, G.: Digital photography: A primer forpathologists. J. Clin. Lab. Anal., 18(2):91–128, 2004.
  15. Riley, R.S., Hogan, T.F., Pavot, R., Forysthe,.R., Massey, D., Smith, E., Wright, Jr. Ben-Ezra, J.M.: A pathologist’s perspective on bone marrow aspiration and biopsy: I. Performing a bone marrow examination. J. Clin. Lab. Anal., 18(2):70-90, 2004.
  16. Massey, D., King, A., and Riley, R.,: Renal allograft dysfunction in kidney transplantation. American Society for Clinical Pathology Clinical Chemistry Check Sample No. CC 03-2 (CC-238), 43(2):19-34 , 2003.
  17. Riley, R.S., Idowu, M., Romagnoli, G.: The value of flow cytometry. Advance for Administrators of the Laboratory., 11(7):101-106, 2002.
  18. Riley, R.S., Massey, D., Jackson-Cook, C., Idowu, M., Romagnoli, G.: Immunophenotypic analysis of acute lymphocytic leukemia. Hematol. Oncol. Clin. North Am., 16(2): 245-299, 2002.
  19. Riley, R.S., Ben-Ezra, J.M., Tidwell, A., Romagnoli, G.: Reticulocyte analysis by flow cytometry and other techniques. Hematol. Oncol. Clin. North Am., 16(2): 373-420, 2002.
  20. Riley, R. S., Ben-Ezra, J.M., Massey, D., Cousar, J.: The virtual blood film. Clin. Lab. Med., 22(1): 317-345, 2002.
  21. Maluf, D.G., Fisher, R.A., Riley, R., Wallace, M., Tawes, J., Bu, D., Posner, M.: Immunobiology and long-term graft function in a transplant heterotopic renal rat model. Clin.Transplant., 16(7): 6-14, 2002.
  22. Idowu, M., Riley, R.S., and Ben-Ezra, J.M.: Acute erythroleukemia, FAB M-6 type. ASCP Check Sample Program, 2002.
  23. Riley, R.S., Ben-Ezra, J.M., and Tidwell, A.: Reticulocyte enumeration: Past and present. Lab. Med., 32(10):599-608, 2001.
  24. Stern, A., Riley, R., and Buckley, L.: Worsening of macrophage activation syndrome in a patient with adult onset Still’s disease after initiation of Etanercept therapy. Clin. Rheumatol., 7(4):252-256, 2001,
  25. Ben-Ezra, J.M., St. Louis, M., and Riley, R.S.: Automated malarial detection with the Abbott Cell-Dyn 4000 hematology analyzer. Lab. Hematol., 7:61-64, 2001.
  26. Cesca, C., Ben-Ezra, J.M., and Riley, R.S. Platelet satellitism as presenting finding in mantle cell lymphoma. Am. J. Clin. Pathol. 115:567-570, 2001
  27. Riley, R.S. and Idowu, M.O.: High resolution digital photography. Advance for Administrators of the Laboratory., 10(5):12, 2001.
  28. Riley, R.S., Ben-Ezra, J.M., Goel, R., and Tidwell, A.: Reticulocytes and reticulocyte enumeration. J. Clin. Lab. Anal., 15:267-294, 2001.
  29. Riley, R.S. and Fisher, L.M., Rowe, D.: Clinical utilization of the International Normalized Ratio (INR). J. Clin. Lab. Anal., 14:101-114, 2000.
  30. Saggi, B.H., Fisher, R.A., Bu, D., Tawes, J.W., Riley, R., and Posner, M.P.: Intragraft cytokine expression and tolerance induction in rat renal allografts. Transplantation., 67:206-210, 1999.
  31. Meda, B.A., Riley, R.S., and Rogers, J.S., II.: Gelatinous transformation of the bone marrow in anorexia nervosa: a case report and review. Lab. Hematol., 3(2):117-122, 1997.
  32. Riley, R. S., Friedline, J., Rogers, J. S., II.: Antiphospholipid antibodies: standardization and testing. Clin. Lab. Med., 17(3):395-430, 1997.
  33. Hogan, T. F., Riley, R. S., and Thomas, J. G.: Rapid diagnosis of acute eosinophilic pneumonia (AEP) in a patient with respiratory failure using bronchoalveolar lavage (BAL) with calcofluor white (CW) staining. J. Clin. Lab. Anal., 11(4):202-207, 1997.
  34. Riley, R.S., Friedline, J.A., Ritchey, A.K., and Ware, R.E.: Recent advances in the diagnosis and management of paroxysmal nocturnal hemoglobinuria. American Society of Clinical Pathologists, ASCP Check Sample Program, Clinical Hematology Section (CH 97-5, CH-23), 3(5): 65-99,1997.
  35. Menello, J.M., Riley, R.S., and Thomas, J.G.: Severe hemolytic anemia caused by Clostridium perfringes. American Society of Clinical Pathologists, ASCP Check Sample Program, Clinical Microbiology Section (Vol. 39:260, MB 96-9, MB-260), 1996.
  36. Maymind, M., Thomas, J.G., Abrons, H.L., and Riley, R.S.: Laboratory implementation of a rapid three-stain technique for detection of microorganisms from lower respiratory specimens. J. Clin. Lab. Anal., 10:104-109, 1996.
  37. Wiley, J., Posekany, K., Riley, R., Holbrook, T., Silverman, J., Joshi, V., Bowyer, S.: Cytogenetic and flow cytometric analysis of a pancreatoblastoma. Cancer Genet. Cytogenet., 79(2): 115-118, 1995.
  38. Riley, R.S.: Paroxysmal nocturnal hemoglobinuria: New discoveries about an old disease. J. Clin. Lab. Anal., 8:335-341, 1994.
  39. Riley, R.S.: The prognostic significance of DNA ploidy and proliferative activity in cancer of the female breast. Current Surg., 50 (8):50-55, 1993.
  40. Lee,T.K., Wiley, A.L. Jr, Esinhart, J.D., Riley, R.S., and Blackburn, L.D.: Variations associated with tissue disaggregation methods in DNA flow cytometry. Anal. Quant. Cytol. Histol., 15(3): 195-200, 1993.
  41. Riley, R.S., Taylor, D., Thomas, J.T., and Ross, W.S.: Histocompatibility testing for the sensitized allograft recipient. ASCP Check Sample Program, Immunopathology Section, Immunopathology No. IP92-5 (IP-98), 1993.
  42. Thomas, J.M., Carver, F.M., Cunningham, P.R., Gross, U., Verbanac, K.M., Rebellato, L.M., Riley, R., and Thomas, F.T.: Donor bone marrow infusion suppresses alloantibody response in RATG-treated recipients: A correlate of long survival. Transpl. Proc.,, 25:342-343, 1993.
  43. Rebellato, L., Gross, U., Carver, M., Cunningham, P., Riley, R., Ross, W., Knowles, R., and Thomas, J.: Treatment of Rhesus monkey allograft recipients with a combination of anti-T-cell monoclonal antibodies. Transpl. Proc.., 25:598-599, 1993,
  44. Riley, R.S.: Cellular proliferation markers in the evaluation of human cancer. Clin. Lab. Med., 12:163-199, 1992.
  45. Elsheikh, T.M., Silverman, J.F., McCool, J.W., Riley, R.S.: Comparative DNA analysis of solid tumors by flow cytometry and image analysis of touch imprints and flow cell suspensions. Am. J. Clin. Pathol., 98:296-304, 1992.
  46. Norris, H.T., Bode, A.P., Catrou, P.G., Christie, J.D., Gagnon, G.A., and Riley, R.S.: Fundamental issues in patient care and diagnostic approach. Current Sur., 48:101-107, 1991.
  47. Riley, R.S., Forney, R.F., Bradley, C.A., and Dunn, D.: Alpha-1-antitrypsin: New perspectives and clinical importance. Clin. Immunol. Newslr., 10: 95-99, 1990.
  48. Riley, R.S.: Cytoplasmic fluorescence in FANA testing. CAP Today, 2(5), 20-21, 1988.
  49. Riley, R.S. and Pence, B.: In-situ hybridization in diagnostic pathology. CAP Today, 2(2), 26, 1988.
  50. Kandzari, S.J., Riley, R.S., and Belis, J.A.: Histopathological effects of 125Iodine implantation. Prostate, 9(4):319-326, 1986.
  51. Moss, A.H. Riley, R.S., Murgo, A.J. and Skaff, L.A.: Over-the-counter Ibuprofen and nephritic syndrome. Ann. Int. Med., 105:303, 1986.
  52. Kandzari, S.J., Belis, J.A., Kim, K.C., Gnepp, D.R., and Riley, R.S.: Clinical results of early stage prostatic cancer treated by pelvic lymphadenopathy and 125Iodine implantation. J. Urol., 127:923-927,1982.
  53. Blair, P.A., Gnepp, D.R., Riley, R.S., and Sprinkle, P.M.: Blastomycosis of the larynx – Report of a case and review of the literature. South. Med. J., 74:880-882, 1981.
  54. Riley, R.S. and Rafter, G.W.: Further studies on the activation of (Na++K+)-dependent ATPase by a leukocytic product. Biochem. et Biophys. Acta, 410:832, 1975.
  55. Riley, R.S. and Rafter, G.W.: Activation of (Na++K+)-dependent ATPase by a leukocytic product: Modification of the reaction product. Fed. Proc., 34:506, 1975.
  56. Riley, R.S. and Rafter, G.W.: Activation of rabbit brain microsomal (Na++K+)-dependent ATPase by a leukocytic product. Biochem. et Biophys. Acta, 381:120, 1975.
  1. Zhao, S., Ladd, A., Dumar, C., Marcavagem, D., Sana, S., Smith, E., Riley, R., Ferreria- Gonzalez, A., Wilkinson, D.S., Garrett, C., and Ben-Ezra, J. Detection and quantitation of the fusion PML-RARa nRNA in acute promyelocytic leukemia with t(15;17) by a single step real-time Taqman PCR procedure. Lab. Hematol. 11:Abst. A24, 2005
  2. Maluf, D.G., Fisher, R.A., Riley, R., Wallace, M., Tawes, J., Bu, D., Posner, M.: Immunobiology and long-term graft function in a transplant heterotopic renal rat model. SEOPF Report, January, 2002.
  3. Zhao, S., Calvin, L., Chang, S., Guo, J.Q., Arlinghaus, R., Riley, R., and Andreeff, M.: Detection of BCR-ABL fusion mRNA, protein, and Ph+ chromosome in CML patients with complete clinical remission: A comparison study by real-time Taqman PCR, RT-PCR, Western blot, and cytogenetics., Blood 98(11):269b,2001.
  4. Ben-Ezra, J.M. and Riley, R.S.: Detection of malaria infection by the Cell-Dyn® 4000 automated hematology analyzer. Blood, 94(10, Suppl. 1), 5b, 1999.
  5. Brooks, K.P., Alboronoz, L., and Riley, R.S.: Amniotic fluid lamellar body number density on the Abbott Cell-Dyn 3500 compared with other measures of fetal lung maturity. Am. J. Clin. Pathol., 103, 431, 1996.
  6. Riley, R.S., Nestor, S., Hare, J., and Hall, S.: Utilization of an automated hematology analyzer for red and white blood cell enumeration in body fluid specimens. Am. J. Clin. Pathol., 103, 422, 1996.
  7. Faynor, S.M., Brooks, K.P., and Riley, R.S.: Comparison of the Abbott Cell-Dyn 3500 and the Coulter STKS in determination of amniotic fluid lamellar body number density, Clin. Chem., 41(6):S164, 1995.
  8. Maymind, M., Thomas, J., and Riley, R.: Implementation of new, rapid staining techniques for selected lower respiratory specimens, emphasizing Calcofluor White. Am. J. Clin. Pathol., 102:550, 1994.
  9. Riley, R., Ross, W.: Detection of antinuclear antibodies by flow cytometry. Am. J. Clin. Pathol., 100:343, 1993.
  10. Riley, R., Ross, W.: A comparative study of reticulocyte enumeration by flow cytometry and light microscopy in patients with sickle cell anemia. Am. J. Clin. Pathol., 100:335-336, 1993.
  11. Posekany, K.J., Riley, R.S., Gagnon, G.A., and Holbrook, C.T.: Bimodal CD45 fluorescence distribution in precursor B-cell acute lymphoblastic leukemia. Am. J. Clin. Pathol., 96:423-424, 1991.
  12. Elsheikh, T.M., Silverman, J.F., McCool, J.W., and Riley, R.S.: Comparative DNA analysis of solid tumors by flow cytometry and image analysis. Am. J. Clin. Pathol., 96:402, 1991.
  13. Forney, J.R., Riley, R.S., And Griffith, K.M.: Characterizing the alpha-1-antitrypsin isoform response in acute inflammation. Proceeding of the Society of Armed Forces Medical Laboratory Scientists, Washington, D.C., 1988.
  14. Riley, R.S., Mahin, E.J., Ashraf, M., Boyd, C.B., Perfetto, S.P., and Griffith, K.: Flow cytometric analysis of uterine cervical aspirates. Am. J. Clin. Pathol., 88(4):532, 1987,
  15. Riley, R.S., Forney, R.F., Brestel, E.A., Koss, W., and Griffith, K.: Demonstration of an acute inflammatory response in acute and chronic uticaria. J. South. Med. Assoc., 80(9):S58, 1987.
  16. deAndrade, R., Jordan, K., McCormick, S., Rogers, J., Riley, R., Raich, P., Koss, W., Shamma, J., and Fontana, J.: Immunoblastic lymphoma in a patient with acquired immune deficiency syndrome (AIDS). American College of Physicians, 6th Annual Meeting, Washington, D.C., 1985.
  17. Moreland, L., DiBartolomeo, A., and Riley, R.: Polyarteritis nodosa presenting as a renal mass in a patient with rheumatoid arthritis. American College Of Physicians, Washington, DC, 1985.
  18. Jagannathan, S.N., Caterson, B., and Riley, R.S.: Immunohistochemical location of proteoglycan monomers in human arteries using monoclonal antibodies directed against proteoglycan substructures. 7th International Symposium on Atherosclerosis, Sydney, Australia, October, 1985.
  19. Riley, R.S.: Prostatic adenocarcinoma: Histological effects of treatment with 125I-seed implantation. Am. J. Clin. Pathol., 78(2):269-270, 1982.



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