Education

Biography

Dr. Feng’s integrated training, experience and expertise in cancer education, clinical practice, community service, cancer research and cancer patient care enable him to incorporate essential components of knowledge, clinical skills, biomedical research, community outreach and service into high quality patient care and medical education. Dr. Feng received his Ph.D. training in Cellular and Molecular Physiology and PharmD training specialized in pharmacy education and clinical pharmacy practice. He started biomedical research career nineteen years ago in the Department of Dermatology, School of Medicine at Stony Brook. After three years of fellowship, he continued research and teaching as an Assistant Professor in Department of Dermatology, School of Medicine, State University of New York at Stony Brook for another 4 years. Currently he is teaching at California Northstate University College of Medicine and College of Pharmacy as Professor of Pharmacology and Oncology. He also has administrative role as Associate Dean for Student Affairs, Admissions and Outreach at California Northstate University College of Medicine. He has over twenty years of clinical and biomedical research experience in cancer, wound healing, and cardiovascular diseases. He also practices as a clinical pharmacist at Sutter Davis Hospital and oncology pharmacy specialist at Dignity Health Medical Foundation. His current research interests include drug discovery for anti-angiogenesis therapy and tumor metastasis, and application of pharmacogenomics in patient care. Two US patents on strategies of anti-angiogenesis and cancer treatments have recently been issued for Dr. Feng. Personalizing pharmacotherapy using pharmacogenomics has always been his professional passion. He edited a text book on clinical application of pharmacogenomics in therapeutics.

Research Interest

Angiogenesis, Wound healing, Pharmacology, Oncology and Pharmacogenomics

Scientific Activities:

Teaching Experience

Professional Activities

Honors & Awards

Publications

1. Yingqi Zhang, Seumsack Dennis Somtakoune, Mario Listiawan, Christina Cheung, Xiaodong Feng.Therapeutic Application of Pharmacogenomics in Oncology (invited clinical review). AAPSJ. 2016; 18(4): 819-29. doi: 10.1208/s12248-016-9926-x
2. Seumsack Dennis Somtakoune, Yingqi Zhang, Myron Phillip Todd, Heather Cohen, Xiaodong Feng. Cancer Vaccines and Immunotherapy for Tumor Prevention and Treatment. US Pharm. 2015; 41(2) (Specialty&Oncologysuppl): 13-18.
3. Xiaodong Feng, Randall L. Mello, Mario Listiawan, Robert Quadro. Future Medicine for Today’s Cancer Patients: Therapeutic Application of Pharmacogenomics in Oncology (invited clinical review). J Pharmaceutical Care and Health Sciences. J Pharma Care Health Sys. 2014 1: 119. doi: 10.4172/2376-0419.1000119
4. Xiaodong Feng. Angiogenesis and Antiangiogenesis Therapies: Spear and Shield of Pharmacotherapy (invited editorial). J Pharmaceutical Care and Health Sciences. 2014; 1(3); doi:10.4172/jpchs.1000e110.
5. Xiaodong Feng, Amie Cai, Kevin Dong, Wendy Chaing, Kevin Yamashiro, Tibebe Woldemariam, and Bin Guan. Assessing Risks of Impaired Healing and Osteomyelitis Associated with Bisphosphonates Using FDA Adverse Event Reporting System (FAERS).J Pharmacovigilance 3: 158. doi: 0.4172/2329-6887.1000158
6. Vyas D, Bhutada N, Ofstad W, Feng X. Comparing a Simulation Based Introductory Pharmacy Practice Experience (IPPE) to Traditional Direct Patient Care IPPEs. Pharmacy Education: An International Journal for Pharmaceutical Education. 2014; (14); 1-9.
7. Xiaodong Feng, Wendy Chaing, Dang-Khoa Huynh and Jenny Nhi Boi Chau. Metformin and Cancer Control: Beyond glycemia (invited clinical review). US Pharmacist. 2014; 39 (9) (Specialty & Oncology suppl): 3-7.
8. Xiaodong Feng: Cell Based Immunotherapy for Cancer (invited clinical review). US Pharm. 2013; 38(9) (Oncology suppl): 8-11.
9. Xiaodong Feng, Marcia Tonnesen, Shaker A. Mousa, Richard. Clark. Fibrin and Collagen Differentially but Synergistically Regulate Sprout Angiogenesis of Human Dermal Microvascular Endothelial Cells in 3-Dimensional Matrix. International Journal of Cell Biology International Journal of Cell Biology. 2013; vol2013:1-11
10. Feng X, Cai A, Dong K, Chaing W, Feng M, et al. Assessing Pancreatic Cancer Risk Associated with Dipeptidyl Peptidase 4 Inhibitors: Data Mining of FDA Adverse Event Reporting System (FAERS). J Pharmacovigilance. 2013; 1: 110. doi:10.4172/2329-6887.1000110
11. Feng X, Dong K, Pham D, Pence S, Inciardi J, Bhutada NS. Efficacy and cost of single-dose rasburicase in prevention and treatment of adult tumor lysis syndrome: a meta-analysis. J Clinical Pharmacy and Therapeutics. 2013 Apr 3. doi: 10.1111/jcpt.12061. [Epub ahead of print]
12. Xiaodong Feng, Deepti Vyas and Bin Guan: Novel Immune and Target Therapy for Skin Cancer. US Pharmacist (invited clinical review) (Hematology and Oncology suppl): 2012; 37 (11) (Oncology suppl): 7-11.
13. Deepti Vyas, PharmD, Nilesh S. Bhutada, Xiaodong Feng. Patient Simulation to Demonstrate Students’ Competency in Core Domain Abilities Prior to Beginning Advanced Pharmacy Practice Experiences. American Journal of Pharmaceutical Education 2012; 76 (9) Article 176.
14. Xiaodong Feng, et al. Pharmacogenomic Biomarkers for Toxicities Associated with Cancer Therapy. US Pharmacist. (Hematology and Oncology suppl): 2012 ;37(1): 2-7.
15. Xiaodong Feng, Brad Brazill, and David Pearson. Therapeutic Application of Pharmacogenomics in Oncology: Selective Biomarkers for Cancer Treatment. (invited clinical review)US Pharmacist. 2011; 36(11) (Hematology and Oncology suppl): 5-12.
16. Xiaodong Feng, William Ofstad and David Hawkins. Antiangiogenesis therapy: a new strategy for cancer treatment (invited clinical review). US Pharmacist. 2010; 35(7) (Oncology Suppl): 4-9.
17. Berhane Ghebrehiwet, Boon-Leong Lim, Rajeev Kumar, Xiaodong Feng, Ellinor IB Peerschke. Effects of surfactants on the stabilization of the bovine lactoperoxidase activity. Biotechnology Progress. 2008; 14 (4): 653-656.
18. Berhane Ghebrehiwet, Boon-Leong Lim, Rajeev Kumar, Xiaodong Feng, Ellinor IB Peerschke. Biosynthesis and secretion of tremerogen a-10, a polysioprenyl peptide mating pheromone of tremella mesenterica.European Journal of Biochemistry. 2008; 147(3): 489-493.
19. Mousa SA, Davis FB, Mohamed S, Davis PJ, Feng X. Pro-angiogenesis action of thyroid hormone and analogs in a three-dimensional in vitro microvascular endothelial sprouting model.Int Angiol. 2006 Dec; 25(4): 407-13.
20. Shaker Mousa, Xiaodong Feng, et al. Synthetic Oligosaccharide Stimulates and Stabilizes Angiogenesis: Structure-Function Relationships and Potential Mechanisms. J Cardiovasc Pharmacol. 2006 Aug; 48(2): 6-13.
21. Berhane Ghebrehiwet, Boon-Leong Lim, Rajeev Kumar, Xiaodong Feng, Ellinor IB Peerschke. Inflammation, immunity, vaccines for helicobacter infection. Helicobacter. 2006; 11(S1): 21-26.
22. Berhane Ghebrehiwet, Xiaodong Feng, et al. Complement component C1q induces endothelial cell adhesion and spreading through a docking/signaling partnership of C1q receptors and integrins. Int Immunopharmacol. 2003; 3(3): 299-310.
23. Xiaodong Feng, Marcia G. Tonnesen, Ellinor I.B. Peerschke, and Berhane Ghebrehiwet. C1q-mediated endothelial cell adhesion and spreading. J. Immunology. 2002; 168(5): 2441-2448.
24. Berhane Ghebrehiwet, Boon-Leong Lim, Rajeev Kumar, Xiaodong Feng, Ellinor I.B. Peerschke. GCiq/p33, a member of a new class of multifunctional and multicompartmental cellular proteins, is involved in inflammation and infection. Immunology reviews. 2001; 180, 129-141.
25. Marcia G. Tonnesen, Xiaodong Feng, Richard A.F. Clark. Angiogenesis in wound healing. J. Invest. Derm. 2000; 5; 40-46.
26. Xiaodong Feng, Richard A.F. Clark, Dennis Galanakis, Marcia G. Tonnesen, Fibrin and collagen differentially regulate human dermal microvascular endothelial cell integrins: stabilization of av/b3 mRNA by fibrin. J. Invest. Derm. 1999; 113(6), 913-919.
27. Xiaodong Feng, Yingnian Cai, K.E. Dawes, G.J. Laurent. Study on chemotaxis and DNA synthesis of pulmonary artery smooth muscle cells. Chinese J. of Tuberc and Respiring Diseases. 1997. 20(2).80-83.
28. Xiaodong Feng, Yingnian Cai and Xixian Deng. Study on the effect of endothelin, nitric oxide and hypoxia on collagen synthesis and calcium influx of pulmonary artery smooth muscle cells. Chinese Journal of Applied Physiology. 1997; 13(1).
29. Xiaodong Feng and Yinnian Cai. Hypoxia and endothelin –1 stimulate DNA synthesis of pulmonary artery smooth muscle cells. Chinese Medical Sciences Journal. 1996; 11(1): 28-31.
30. Yingnian Cai, Lan Luo, Shiqiang Li and Xiaodong Feng. Hypoxia stimulates DNA synthesis and c-myc gene expression of newborn calf pulmonary artery smooth muscle cells. Chinese J. of Physiological Sciences. 1996; 12(1): 189-191.
31. Xiaodong Feng, Yingnian Cai and Xixian Deng. Study on the effect of endothelin, nitric oxide and hypoxia on collagen synthesis and calcium influx of pulmonary artery smooth muscle cells. Chinese Journal of Applied Physiology. 1996; 12(3): 212-215.
32. Xiaodong Feng and Yingnian Cai. The endothelium derived factors and hypoxic pulmonary hypertension (review). Clinics and Basic Medical Sciences. 1996; 16(1): 6-10.
33. Xiaodong Feng, Yingnian Cai, K.E. Dawes and G,J, Laurent. Endothelian-1 induces chemotaxis of pulmonary artery smooth muscle cells. Acta Academiae Medicinae Scinicae. 1996; 18(5): 338-342.
34. Xiaodong Feng and Yinnian Cai, Study on the effect of endothelin-1 and nitric oxide on DNA synthesis of pulmonary artery smooth muscle cells and modulation of hypoxia. ActaAcademy Medicinae Scinicae. 1995; 17(3): 172-177.
35. Xiaodong Feng and Yingnian Cai. Mitogenic effect of endothelin-1 on pulmonary artery smooth muscle cells under hypoxia. Chinese J. of Applied Physiology 1995; 11(3): 197-200.
36. Xiaodong Feng and Yingnian Cai. Hypoxia stimulates the expression of heat shock protein 70 in cultured pulmonary smooth muscle cells. Acta Physiology Sinica. 1995; 47(5):448-452.
37. Xiaodong Feng and Yingnian Cai. Mitogenic effect of endothelin-1 on vascular smooth muscle cells (review). Chinese Journal of applied Physiology. 1994; 10(2):189-191.