Toru Watanabe, PhD
Clinical associate professor of Pediatrics
  • :+81-25-281-5151
    • :+81-25-281-5169

Niigata City General Hospital
Japan

Education

  • Ph.D. (Dr. of Medical Science), Niigata University Graduate School of Medical and Dental Sciences, 2002
  • Thesis: Glomerular CD8+ cells predict progression of childhood IgA nephropathy M.D., Niigata University, 1985

 

Biography

Dr. Toru Watanabeis an associate manager ofthe Department of Pediatrics, Niigata City General Hospital in Japan. He graduated from Niigata University School of Medicine in 1985, and has been working at the Department of Pediatrics, Niigata City General Hospital until now.He joined theDepartment of Cell Biology, Institute of Nephrology, Faculty of Medicine, Niigata University, from 1997 to 2001 as a guest researcher and got a PhD in 2002. His specialty ismainly pediatric nephrology, especially renal tubular disorders.
He was given the Plenary Presentation Award in 1994 and the Best Clinical Research Award in 1999 from the Japanese Society for Pediatric Nephrology, an Honorary Title of Leading Article to his article in 2013 from European Journal of Pediatrics, a Key Scientific Article, featured in Global Medical Discovery (Canada) in 2013, and a Cutting-Edge Biomedical Research, featured in World Biomedical Frontiers (USA), 2013.

During his career, he published more than 80 peer papers in peer reviewed international journals. He has reviewed more than 300 manuscripts submitted to international journalsincluding JAMA, Am J Kidney Dis, World J Nephrol, Ren Fail, Pediatr Nephrol, J Pediatr,Pediatrics and others. He is an editorial board member of 21 international journals (JNephrolRes, J Nephrol Urol, J Urol Res, Am J Clin ExpMed, World J Nephrol, Pediatr Nephrol and others) and one Japanese journal (Jpn J PediatrNephrol).

Research Interest

  • Nephrology
  • Electrolyte disorders
  • Pediatric Urology
  • Kawasaki disease
  • Vasculitis

 

Professional Activities:

Professional License

  • PALS (Pediatric Advanced Life Support) provider, certified by the AHA, 2004
  • Fellow of the Japan Pediatric Society, the Japan Pediatric Society, 1991
  • Japanese Medical Doctor License, the Japanese Ministry of Welfare, 1985

Career

  • Chief, Section of Medical Education and Training, Niigata City General Hospital, 2004-
  • Sub-chief, Department of Pediatrics, Niigata City General Hospital, 2000-
  • Staff, Department of Pediatrics, Niigata City General Hospital, 1991-1999
  • Resident, Department of Pediatrics, Niigata City General Hospital, 1985-1990

Awards and Honors

  • The plenary presentation award, the Japanese Society for Pediatric Nephrology, 1994
  • The best clinical research award, the Japanese Society for Pediatric Nephrology, 1999
  • The honorary title of leading article: Renal complications of seasonal and pandemic influenza A virus infections, European Journal of Pediatrics (Belgium), 2012
  • Key Scientific Article (Renal complications of seasonal and pandemic influenza A virus infections, European Journal of Pediatrics 2013;172:15-22), Global Medical Discovery (Canada), 2013
  • Cutting-edge biomedical research (Renal complications of seasonal and pandemic influenza A virus infections, European Journal of Pediatrics 2013;172:15-22), World Biomedical Frontiers (USA), 2013

 

Publications

  1. Watanabe T, Abe T, Satoh M, Oda Y, Takada T, Yanagihara T: Two children with bromate intoxication due to ingestion of the second preparation for permanent hair waving. Acta Pediatr Jpn 1992; 34:601-605
  2. Watanabe T, Satoh M, Abe T, Hayashi M, Oda Y: Stroke and meningitis in a case of SLE with anti-phospholipid antibodies. Acta Pediatr Jpn 1993; 35:423-425
  3. Watanabe T, Satoh M, Oda Y: Human parvovirus B19 encephalopathy. Arch Dis Child 1994; 70:71
  4. Watanabe T, Miyakawa K, Satoh M, Abe T, Oda Y: Kabuki make-up syndrome associated with chronic idiopathic thrombocytopenic purpura. Acta Pediatr Jpn 1994; 36:727-729
  5. Yuasa H, Ito M, Oiso Y, Kurokawa M, Watanabe T, Oda Y, Ishizuka T, Tani N, Ito S, Shibata A, Saito H: Novel mutations in the V2 Vasopressin receptor gene in two pedigrees with congenital nephrogenic diabetes insipidus. J Clin Endcrinol Metab 1994; 79:361-365
  6. Watanabe T, Takada T, Kihara I, Oda Y: Three cases of Henoch-Schönlein purpura preceded by IgA nephropathy. Pediatr Nephrol 1995; 9:674
  7. Watanabe T, Oda Y: Rhabdomyolysis and acute renal failure in acute necrotizing encephalopathy with influenza A. Pediatr Nephrol 1998; 12:85
  8. Watanabe T, Sato M, Abe T, Oda Y: Bacterial croup caused by Pasteurella haemolytica. Acta Pediatr Jpn 1998; 40:360-361
  9. Watanabe T: Serum ferritin levels in acute renal failure. Clin Nephrol 1998; 50:336
  10. Yoshikawa H, Watanabe T, Oda Y: Selective, reversible thalamic involvement with influenza A infection. Pediatrics 1998; 102:1494-1495
  11. Watanabe T: Urinary excretion of podocytes in patients with sepsis. Pediatr Nephrol 1999; 13:632-633
  12. Yoshikawa H, Watanabe T, Abe T, Oda Y: Clinical diversity in acute necrotizing encephalopathy. J Child Neurol 1999; 14:249-255
  13. Watanabe T, Oda Y: Henoch-Schönlein purpura nephritis associated with human parvovirus B19 infection. Pediatr Int 2000; 42:94-96
  14. Watanabe T, Abe T, Oda Y: Exercise-induced acute renal failure in a patient with renal hypouricemia. Pediatr Nephrol 2000; 42:851-852
  15. Watanabe T: Pseudohypoaldosteronism type 1 and respiratory distress syndrome. Pediatr Nephrol 2000; 14:884
  16. Watanabe T: Gitelman syndrome with hypocalciuria and normomagnesemia. Clin Exp Nephrol 2000; 4:271
  17. Watanabe T: Congenital penoscrotal lymphedema complicated by sepsis associated with a streptococcal infection. Pediatr Emerg Care 2000; 16:423-425
  18. Yoshikawa H, Watanabe T, Abe T, Sato M, Oda Y: Japanese siblings with congenital chloride diarrhea. Pediatr Int 2000; 42:313-315
  19. Yoshikawa H, Watanabe T, Abe T, Oda Y, Ozawa K: Haloperidol-induced rhabdomyolysis without neuroleptic malignant syndrome in a handicapped child. Brain Dev 2000; 22:256-258
  20. Watanabe T, Onda H: Henoch-Schönlein purpura with antiphospholipid antibodies following an influenza vaccination. Pediatr Nephrol 2001; 16:458-459
  21. Watanabe T, Kawachi H, Ikezumi Y, Yanagihara T, Oda Y, Shimizu F: Glomerular CD8+cells predict progression of childhood IgA nephropathy. Pediatr Nephrol 2001; 16:561-567
  22. Watanabe T, Yohsizawa N: Recurrence of acute poststreptococcal glomerulonephritis. Pediatr Nephrol 2001; 16:598-600
  23. Watanabe T: Hemolytic uremic syndrome associated with influenza A virus infection. Nephron 2001; 89:359-360
  24. Watanabe T: Rhabdomyolysis and acute renal failure in children. Pediatr Nephrol 2001; 16:1072-1075
  25. Yoshikawa H, Yamazaki S, Watanabe T, Abe T: Study of influenza-associated with encephalitis/encephalopathy in children during the 1997 to 2001 influenza seasons. J Child Neurol 2001; 16:885-890
  26. Yoshikawa H, Watanabe T, Abe T: Tubulo-interstitial nephritis caused by sodium valproate. Brain Dev 2002; 24:102-105
  27. Watanabe T: Patchy renal vasoconstriction after exercise in a child without renal hypouricemia. Pediatr Nephrol 2002; 17:284-286
  28. Watanabe T, Abe T, Oda Y: Exercise-induced acute renal failure in a patient with renal hypouricemia (overview). Urol Rev J 2002; 1:15-16
  29. Watanabe T: Membranous glomerulonephritis in a patient with unilateral renal agenesis. Nephron 2002; 91:159-161
  30. Yoshikawa H, Watanabe T, Abe T: Fanconi syndrome caused by sodium valproate: report of three severely disabled children. Eur J Paediatr Neurol 2002; 6:165-167
  31. Watanabe T, Nitta K: Hepatic glomerulosclerosis in a child with extrahepatic portal vein obstruction. Pediatr Int 2002; 17:456-459
  32. Watanabe T: Reflux nephropathy in a patient with crossed renal ectopia with fusion. Pediatr Nephrol 2002; 17:617-619
  33. Watanabe T, Nitta K: Transient hyporeninemic hypoaldosteronism in acute glomerulonephritis. Pediatr Nephrol 2002; 17:959-963
  34. Watanabe T, Yamazaki A: Pneumothorax and transient pseudohypoaldosteronism in an infant with hydronephrosis. Pediatr Nephrol 2003; 18:62-64
  35. Watanabe T: Acute renal failure in Kawasaki disease. Pediatr Nephrol 2003; 18:200
  36. Watanabe T: Ataxia as a delayed reaction to contrast medium for an intravenous pyelography. Pediatr Nephrol 2003; 18:303
  37. Watanabe T: Reversible secondary pseudohypoaldosteronism. Pediatr Nephrol 2003; 18:486
  38. Yoshikawa H, Yamazaki S, Watanabe T, Abe T: Vitamin K deficiency in severely disabled children. J Child Neurol 2003; 18:93-97
  39. Yoshikawa H, Yamazaki S, Watanabe T, Abe T: Hypouricemia in severely disabled children: influence of valproic acid and bed-ridden state. Brain Dev 2003; 25:186-190
  40. Watanabe T, Yoshikawa H, Abe Y, Yamazaki S, Uehara Y, Abe T: Renal involvement in children with influenza A virus infection. Pediatr Nephrol 2003; 18:541-544
  41. Watanabe T, Iwabuchi H, Oishi M: Accidental hypothermia in an infant with Prader-Willi syndrome. Eur J Pediatr 2003; 162:550-551
  42. Watanabe T: Renal involvement in human parvovirus B19 infection. Pediatr Nephrol 2003; 18:966-967
  43. Abe Y, Watanabe T: Pertussis pneumonia complicated by a hyponatremic seizure. Pediatr Emerg Care 2003; 19:262-264
  44. Watanabe T, Okazaki E, Shibuya H: Influenza A virus-associated encephalopathy with haemophagocytic syndrome. Eur J Pediatr 2003; 162:799-800
  45. Watanabe T, Iwabuchi H, Abe T: Rhabdomyolysis in a patient with Kawasaki disease. Eur J Pediatr 2003; 162:891-892
  46. Watanabe T, Abe Y: Muscle involvement in a patient with Henoch-Schönlein purpura nephritis. Pediatr Nephrol 2004; 19:227-228
  47. Watanabe T: Hyponatremia and hyperkalemia in infants with acute pyelonephritis. Pediatr Nephrol 2004; 19:361-362
  48. Watanabe T, Onda H: Hemichorea with antiphospholipid antibodies in a patient with lupus nephritis. Pediatr Nephrol 2004; 19:451-453
  49. Watanabe T: Hemolytic uremic syndrome associated with Epstein-Barr virus infection. Pediatr Nephrol 2004; 19:569
  50. Watanabe T: Ulcerative colitis that developed 8 years after human parvovirus B19 encephalopathy. Eur J Pediatr 2004; 163:341-342
  51. Watanabe T: Megalin and proximal renal tubular dysfunction in Dent disease. Pediatr Nephrol 2004;19:1305
  52. Watanabe T: Proximal renal tubular dysfunction in primary distal renal tubular acidosis. Pediatr Nephrol 2005;20:86-88
  53. Watanabe T, Nakayasu K, Nagayama Y: Autoimmune haemolytic anaemia and renal Fanconi syndrome caused by valproate therapy. Eur J Pediatr 2005;164:186-187
  54. Watanabe T, Tajima T: Renal cysts and nephrocalcinosis in a patient with Bartter syndrome type III. Pediatr Nephrol 2005;20:676-678
  55. Watanabe T, Yoshikawa H, Yamazaki S, Abe Y, Abe T: Secondary renal Fanconi syndrome caused by valproate therapy. Pediatr Nephrol 2005;20:814-817
  56. Watanabe T, Yamazaki A, Kurabayashi T, Hanaoka J: Familial multicystic dysplastic kidney. Pediatr Nephrol 2005;20:1200
  57. Watanabe T: IgA deficiency and membranous glomerulonephritis. Pediatr Nephrol 2006;21:131
  58. Watanabe T: Traumatic spinal epidural hematoma without bone disruption. Eur J Pediatr 2006;168:278-279
  59. Watanabe T: Hyponatremia in Kawasaki disease. Pediatr Nephrol 2006;21:778-781
  60. Watanabe T: Pathogenesis of hyponatremia in Kawasaki disease. Pediatr Nephrol 2006;21:1489
  61. Watanabe T: Syndrome of inappropriate secretion of antidiuretic hormone and Kawasaki disease. Pediatr Nephrol 2006;21:1492
  62. Watanabe T, Iinuma Y, Naito S, Nitta K: Eosinophilic tumor in a patient with bronchial asthma receiving pranlukast. Eur J Pediatr, 2007:166:183-184
  63. Watanabe T: Gitelman syndrome and glomerulonephritis. Pediatr Nephrol 2007;22:474
  64. Watanabe T: Thrombotic microangiopathy and intravenous immunoglobulin therapy. Pediatr Nephrol 2007;22:907-908
  65. Watanabe T, Abe Y, Sato S, Uehara Y, Ikeno K, Abe T: Sterile pyuria in patients with Kawasaki disease originates from both the urethra and the kidney. Pediatr Nephrol 2007;22:987-991
  66. Watanabe T, Yamazaki S, Nagayama Y: Persistent open anterior fontanel in a patient with distal renal tubular acidosis. Eur J Pediatr 2007;166:865-866
  67. Watanabe T, Sato Y: Renal involvement and hypocomplementemia in a patient with acute hemorrhagic edema of infancy. Pediatr Nephrol 2007;22:1979-1981
  68. Watanabe T: Nephrotic syndrome in mesangial proliferative lupus nephritis. Pediatr Int 2007;49:1009-1011
  69. Watanabe T: Parotitis and acute pancreatitis in a patient with ulcerative colitis. Eur J Pediatr 2008;167:945
  70. Watanabe T, Baba Y: Gallbladder wall thickening in a patient with acute poststreptococcal glomerulonephritis. Eur J Pediatr 2009;168:717-719
  71. Watanabe T, Kawashima H: Primary pyomyositis following influenza A virus infection and vigorous exercise. Pediatr Int 2010;52:e96-e97
  72. Watanabe T: Shock following an administration of contrast medium in a patient with Kawasaki disease. Pediatr Radiol 2010;40:1304-1305
  73. Watanabe T: Henoch-Schönlein purpura following influenza vaccinations during the pandemic of influenza A (H1N1). Pediatr Nephrol 2011;26:795-798
  74. Watanabe T: Atypical clinical manifestations of acute poststreptococcal glomerulonephritis. In: An Update on Glomerulopathies – Clinical and Treatment Aspects, Prabhakar S (eds), InTech, Rijeka, pp 151-168 , 2011
  75. Watanabe　T,　Fujita　M,　Hirayama　Y,　Iinuma　Y:　Superior　mesenteric　artery　syndrome　and　acute　pancreatitis in a boy with eating disorder: case report. Open J Pediatr 2011;1:94-97
  76. Abe Y, Sato T, Takagi M, Watanabe T, Nagayama Y, Hasegawa T, Abe T. A case of Rabson-Mendehhall syndrome with novel mutation in the tyrosine kinase domain of the insulin receptor gene complicated by medullary sponge kidney. J Pediatric Endocr Met 2012;25:587-590
  77. Watanabe T, Hideki Hashidate, Yutaka Hirayama, Yasushi Iinuma: Kikuchi-Fujimoto disease following vaccination against human papilloma virus infection and Japanese encephalitis. Eur J Pediatr 2012;171:1409-1411
  78. Watanabe T. Re-expansion pulmonary edema in a boy with spontaneous pneumothorax during an influenza B virus infection. Open J Pediatr 2012;2:261-263
  79. Watanabe T. Renal complications of seasonal and pandemic influenza A virus infection (Leading article). Eur J Pediatr 2013;172:15-22
  80. Watanabe T. Hyponatremia in Kawasaki disease: What does it mean and how does it occur? J Pediatr Biochem 2013;3:85-91
  81. Watanabe T. Acute cystitis in a patient with Kawasaki disease. Int J Clin Pediatr 2013;2:37-39
  82. Watanabe T. Kidney and urinary tract involvement in Kawasaki disease. Int J Pediatr 2013;2013:831834
  83. Abe Y, Watanabe T. Renal tubular dysfunction in patients with molecular defects of the insulin receptor gene. Eur J Pediatr 2014;173:263
  84. Abe Y, Nagasaki K, Watanabe T, Abe T, Fukami M. Association between compound heterozygous mutations of SLC34A3 and hypercalciuria. Hormone Res Pediatr 2014;82:65-71
  85. Watanabe T, Abe Y. Bartter-like syndrome in patients with molecular defect of the insulin receptor gene. Acta Diabetol 2014;51:891-892
  86. Watanabe T. Kawasaki disease with retropharyngeal edema following a black fly bite. Case Rep in Pediatr 2014;2014:296456
  87. Watanabe T. Pyuria in patients with Kawasaki disease. World J Clin Pediatr 2015;4:25-29
  88. Shimada S, Watanabe T, Sato S. A patient with Kawasaki disease following influenza vaccinations. Pediatr Infect Dis J 2015;34:913
  89. Takase M, Watanabe T. Reactivation of immune thrombocytopenia following a Japanese encephalitis vaccination. Pediatr Infect Dis J 2015;34:1276
  90. Watanabe T, Kawashima H. Acute encephalitis and encephalopathy associated with human parvovirus B19 infection in children. World J Clin Pediatr, in press

 

 

 

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