Lawrence R. Poree
Lawrence R. Poree
Professor and Director
  • :415-885-7246
    • :415-885-7575

Department of Anesthesia and Perioperative Care
University of California at San Francisco
Canada

Education

2001-2002 Pain Fellowship, University of California at San Francisco, San Francisco, CA
 
1998-2001 		Anesthesia Residency, Stanford University Medical Center, Stanford, CA.
  1997-1998 Transitional Internship; Santa Clara Valley Medical Center, San Jose, CA
  1993-1997 M.D.; Stanford University School of Medicine
  1988-1989 Postdoctoral Fellowship in Biomedical Engineering and Neuroscience: The Johns Hopkins University School of Medicine

 

Biography

Dr. Poree is medical director at the Pain Clinic of Monterey Bay and Professor in the Department of Anesthesia at the University of California at San Francisco where he trains pain fellows in neuromodulation techniques. He also serves on the board of the North American Neuromodulation Society where he co-authored the NANS neuromodulation training guidelines and the S.A.F.E. principles for incorporating neuromodulation technologies in pain algorithms. He received his PhD from the University of California, Berkeley in Toxicology and went on to do a postdoctoral fellowship in biomedical engineering and neuroscience at Johns Hopkins University where he studied spinal modulation of the sympathetic nervous system. He completed medical school and anesthesia residency at Stanford University and his pain fellowship at the University of California at San Francisco.

Research Interest

Pain management; Neuromodulation; Spinal Cord Stimulation; Intrathecal Therapy; Cancer Pain; Pelvic Pain

Professional Activities:

2015-present Clinical Professor and Director of Neuromodulation Service, Department of Anesthesia, University of California at San Francisco
2012-present Board of Directors for the California Society of Interventional Pain Physicians
2013-2014 Editor of North American Neuromodulation Society Newsletter
2011-present Board of Directors for the North American Neuromodulation Society
2011-2014 Volunteer Associate Professor, Department of Anesthesia;  UCSF

 

Publications

  1. Deer T.R., Mekhail N., Provenzano D., Pope J., Krames E., Leong M., Levy R.M., Abejon D., Buchser E., Burton A., Buvanendran A., Candido K., Caraway D., Cousins M., DeJongste M., Diwan S., Eldabe S., Gatzinsky K., Foreman R.D., Hayek S., Kim P., Kinfe T., Kloth D., Kumar K., Rizvi S., Lad S.P., Liem L., Linderoth B., Mackey S., McDowell G., McRoberts P., Poree L., Prager J., Raso L., Rauck R., Russo M., Simpson B., Slavin K., Staats P., Stanton-Hicks M., Verrills P., Wellington J., Williams K., North R. The Appropriate Use of Neurostimulation of the Spinal Cord and Peripheral Nervous System for the Treatment of Chronic Pain and Ischemic Diseases: The Neuromodulation Appropriateness Consensus Committee. Neuromodulation 2014; 17: 515–550.
  2. Deer, T. R., Mekhail, N., Provenzano, D., Pope, J., Krames, E., Thomson, S., Raso, L., Burton, A., DeAndres, J., Buchser, E., Buvanendran, A., Liem, L., Kumar, K., Rizvi, S., Feler, C., Abejon, D., Anderson, J., Eldabe, S., Kim, P., Leong, M., Hayek, S., McDowell, G., Poree, L., Brooks, E. S., McJunkin, T., Lynch, P., Kapural, L., Foreman, R. D., Caraway, D., Alo, K., Narouze, S., Levy, R. M. and North, R. The Appropriate Use of Neurostimulation: Avoidance and Treatment of Complications of Neurostimulation Therapies for the Treatment of Chronic Pain. Neuromodulation 2014; 17: 571–598. 
  3. Deer, T. R., Krames, E., Mekhail, N., Pope, J., Leong, M., Stanton-Hicks, M., Golovac, S., Kapural, L., Alo, K., Anderson, J., Foreman, R. D., Caraway, D., Narouze, S., Linderoth, B., Buvanendran, A., Feler, C., Poree, L., Lynch, P., McJunkin, T., Swing, T., Staats, P., Liem, L. and Williams, K. (2014), The Appropriate Use of Neurostimulation: New and Evolving Neurostimulation Therapies and Applicable Treatment for Chronic Pain and Selected Disease States. Neuromodulation: 2014; 17: 599–615. 
  4. Epidural Hematomas Following Removal of Percutaneous Spinal Cord Stimulator Trial Leads: Two Case Reports; Giberson,C; Barbosa,J; Brooks, E; McGlothlen, G; Grigsby, E; Kohut, J; Wolbers, L; Poree, L.; 2013 Regional Anesthesia and Pain Medicine • Volume 39, Number 1, 2014
  5. Poree,L; Krames,E; Pope, J; Deer, T; Levy,R; Dhillon,V; Shultz, L: Spinal Cord Stimulation as treatment for Complex Regional Pain Syndrome Should be Considered Earlier than Last Resort Therapy   Neuromodulation 2012.  
  6. Poree, L; Wolbers,L: Spinal Targets for interventional Pain Management: in AAPM Textbook of Pain Medicine; ed: Deer, T. and Leong, M.:  2012;
  7. Krames, Elliot S.;  Monis, Sayed; Poree, Lawrence; Deer, Timothy; Levy, Robert :  Using the SAFE Principles When Evaluating Electrical Stimulation Therapies For the Pain of  Failed  Back  Surgery Syndrome  Neuromodulation: 2011 July/August issue, Volume 14, Number 4 in Press
  8. Henderson, Jaimie.; Levy, Robert ; Bedder, Marshall ; Staats, Peter; Slavin, Konstantin; Poree, Lawrence ; North, Richard  NANS Training Requirements for Spinal Cord Stimulation Devices: Selection, Implantation, and Follow-up.: Neuromodulation 2009 vol 12:3(p 171-174)
  9. Krames, E., Poree, L.R., Deer, T., Levy, R:  Implementing the SAFE Principles for the Development of Pain Medicine Therapeutic Algorithms That Include Neuromodulation Techniques Neuromodulation 2009 vol 12:2(p 104-113)
  10. Krames, E., Poree, L., Deer, T., Levy, R:  Editorial: Neuromodulation for pain management: Pain Medicine Vol. 10:1, 1-5, 2009
  11. Poree, L.R., Guo, T.Z., Kingery, W.S., Maze, M.: The analgesic potency of dexmedetomidine is enhanced after nerve injury: a possible role for peripheral  alpha2-adrenoceptors.  Anesth Analg.  87(4): 941-948,  1998
  12. Kingery, W.S., Guo, T.Z., Poree, L.P., Maze, L.P.:  Colchicine treatment of the sciatic nerve reduces neurogenic extravasation, but does not affect nociceptive thresholds or collateral sprouting in neuropathic or normal rats. Pain 74(1): 11-20, 1998
  13. Guo, T.Z., Poree,L., Golden, W., Fujinaga,M., Maze,M.:  The antinociceptive response to nitrous oxide is medaited by supraspinal opiate and spinal 2 adrenergic recetpors in the rat.  Anesthesiology, 85(4): 846-852, 1996
  14. Poree, L.R. and Schramm, L.P. Role of cervical neurons in propriospinal inhibition of thoracic dorsal horn neurons. Brain.Res. 599:302-308, 1992.
  15. Poree, L.R. and Schramm, L.P. Interaction between medullary and cervical regulation of renal sympathetic activity. Brain.Res. 599:297-301, 1992.
  16. Schramm, L.P., and Poree, L.R.: Medullo-spinal modulation of sympathetic output and spinal afferent input.  J. Cardiovascular Electrophysiology Supp. 2:S18-S25, 1991
  17. Poree,L.P., Dickenson, A.H., and Wei, E.T.: Corticotropin‑releasing factor inhibits the response of trigeminal neurons to noxious heat.  Brain Res.  502:349-355, 1989
  18. Poree,L.P., Dickenson, A.H., and Wei, E.T.: Corticotropin‑releasing factor inhibits the response of trigeminal neurons to noxious heat.  Brain Res.  502:349-355, 1989
  19. Kiang, J.G., Poree, L.R., and Wei, E.T.:  Anti‑inflammatory activity of corticotropin‑releasing factor: II. Mechanisms of action.  Proc. West. Pharmacol. Soc. 30:63‑65, 1987

Abstracts

  1. Timothy Deer MD1, Robert Levy MD PhD2, Eric Grigsby MD3, Kasra Amirdelfan MD4, Lawrence Poree MD5, Peter Staats MD6, David Caraway MD7, Nagy Mekhail MD PhD8, Jeffery Kramer PhD9; A prospective, randomized, multi-center, controlled clinical trial to assess the safety and efficacy of the Spinal Modulation Axium® Neurostimulation System in the treatment of chronic pain (ACCURATE Trial): Trial Design; NANS 2014
  2. Poree, L; Quinn, R.; Wolbers, L; Rawlings, J: Baclofen and Clonidine Withdrawal in Two Patients Due to Mismanagement of Intrathecal Pumps: Two Case Studies that Support the Need For Improved Intrathecal Pump Training Guidelines. NANS 2013
  3. Giberson, C; Barbosa, J. ; Wolbers, L.; Henderson, J; Poree, L: Case Report:  Epidural Hematoma After Removal of Percutaneous SCS Trial Leads 2012 North American Neuromodulation Society
  4. Poree, Lawrence R.  Anatomy, Pathophysiology, and Neuromodulation of the Dorsal Root Ganglion-Why You Should Care; Australian Neuromodulation Society; Neuromodulation 2011;14:89-91
  5. Poree, LR; Krames, E. : Use of anatomical and biochemical techniques to confirm intrathecal catheterization:  A case report.  International Neuromodulation Conference 2007.
  6. Angst,M.S.; Poree,L.R.; Ramaswamy,B.:  Reliable quantification of opioid analgesia with a new experimental pain model in man.  Clinical Pharmacology & Therapeutics 61(2):III1, 1997
  7. Poree LR, Angst MS, Dyck JB. Evaluation of a new experimental electrical pain model in humans. 8th World Congress on Pain, Vancouver, Canada. International Association for the Study of Pain Press, Seattle, Washington, 1996;Abstracts page 332(5).
  8. Angst MS, Poree LR, Dyck JB. Evaluation of sequential, centering and spacing bias in a new experimental pain model in humans. International Association for the Study of Pain Press, Seattle, Washington 1996;Abstracts page 332(6).
  9. Kingery, W.S., Poree,L.R., Guo, T.Z., Maze, M.:  Colchine treatment of the sciatic nerve causes a prolonged reduction of neurogenic extravasation, but does not affect saphenous mediated nociceptive thresholds, autotomy behavior, or saphenous collateral sprouting in normal or sciatic transected rats.  International Association for the Study of Pain 8:27, 1996
  10. Maze, M., Kingery, W.S., Guo, T.Z., Macmillan, L., Limbird, L., Poree,L.R.: Tibial sectioned mice become insensitive to the analgesic but not the sedative effects of dexmedetomidine, and can develop a neuropathic hyeralgesia independent of 2-A receptor function.  International Association for the Study of Pain 8:348, 1996
  11. Angst, M.S., Poree, L.R., Dyck, J.B.: Evaluation of sequential, centering and spacing bias in a new experimental pain model in humans.  International Association for the Study of Pain 8:332, 1996
  12. Poree, L.R., Angst,M.S., Dyck, J.B.:  Evaluation of a new experimental electrical pain model in humans.  International Association for the Study of Pain 8: 332, 1996
  13. Poree, L.R.,  Guo, K.; Limbird, L.; Maze, M:  Dexmedetomidine inhibits nociception in wild type but not transgenic mice with alpha-2A adrenoceptors uncoupled from potassium channels.   American Pain Society meeting,  1995
  14. Poree, L.R.; Guo, K.; Kingery, W.; Maze, M: Analgesic actions of  dexmedetomidine in an animal model of neuropathic pain:  Society for Neuroscience Abstracts 20: 305, 1994
  15. Poree, L.R. and Schramm, L. P.: Role of thoracic interneurons in cervically-evoked sympathoinhibition in the rat. Society for Neuroscience Abstracts 16:216, 1990
  16. Poree, L.R. and Schramm, L. P.: Bilateral injection of muscimol into the rat rostral ventrolateral medulla fails to decrease mean renal nerve activity.  Society for Neuroscience Abstracts 15:592, 1989
  17. Poree, L.R., Dickenson, A.H., and Wei, E.T.: Corticotropin-releasing factor inhibits trigeminal nociceptive neurons.  The Pharmacologist  29:129,  1987.
  18. Poree, L.R. and Wei, E.T.:  Evidence for peripheral inhibitory actions of an enkephalin analog on trigeminal nociceptive neurons.  International Narcotics Research Conference, 18:176,  1987

 

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