Prasad R K Koduru
Prasad R K Koduru
Professor

Department of Pathology
UT Southwestern Medical Center
USA

Education

B.S- Biology

1972

Andhra University, India

M.S- Botany, Specialization in Genetics

1974

Andhra University, India

Ph.D-Cytogenetics

1979

Andhra University, India

MHA- Health Care Administration

2000

Hofstra University, Hempstead, New York

 

Biography

Dr. Prasad Koduru is currently a Professor of Pathology at the University of Texas SouthWestern Medical Center, Dallas. He earned PhD in Genetics and Fellowship trained in clinical cytogenetics and cancer genetics at Memorial Sloan-Kettering Cancer Center. After obtaining Board certification in clinical cytogenetics he joined North Shore University Hospital, Manhasset, NY as Director of cancer genetics laboratory. After spending 22 years at this institution as Chief of Genetics Services, he moved to the current position. He published over 95 research papers, primarily in cancer genetics and cytogenetics. In the current position he supervises the operations cytogenetics and molecular genetics laboratories and provides diagnostics service in clinical cytogenetics, fluorescence in-situ hybridization, chromosome microarray, and molecular diagnostics.

 

Research Interest

Cytogenetics

Cancer genetics

Cancer biomarkers

 

Professional Activities:

  • Founding Fellow, American College of Medical Genetics
  • American Board of Medical Genetics
  • American Society of Human Genetics
  • American Society of Hematology
  • American Society for the Advancement of Science
  • American College of Health Care Executives

 

Publications

  1. Koduru, P.R.K., Krishna Rao, M. 1978. Chromosome pairing and desynapsis in spontaneous autopolyploids of         Pennisetum typhoides. Cytologia 43: 445-452.
  2. Krishna Rao, M., Koduru, P.R.K. 1978. Asynapsis and spontaneous centromeric breakage in an inbred line of         Pennisetum typhoides (L.) Leeke. Proc. Ind. Acad. Sci. B. 87: 29-35.
  3. Krishna Rao, M., Koduru, P.R.K. 1978. Cytogenetics of a factor for formation and male sterility in             Pennisetum americanum. Theor. Appl. Genet. 53: 1-7.
  4. Krishna Rao, M., Koduru, P.R.K. 1978. Inheritance of genetic male sterility in Pennisetum americanum (L.)             Leeke. Euphytica 27: 777-785.
  5.  Krishna Rao, M., Koduru, P.R.K. 1979. Bi-parental plastid inheritance in Pennisetum americanum. J. Heredity          69: 327-330.
  6. Koduru, P.R.K., Krishna Rao, M. 1979. Inheritance of anthocyanin and way stem in Pennisetum. J. Cytol.             Genet. 14: 18-21.
  7.  Krishna Rao, M., Koduru, P.R.K. 1979. Genetics of five hairy phenotypes and a linkage group of Pennisetum      americanum. Euphytica 28: 445-451.
  8. Lakshmi, K.V., Murthy, T.G.K., Koduru, P.R.K. 1979. Cytogenetic behaviour and estimation of phosphate and      potassium content in desynaptic pearl millet. Theor. Appl. Genet. 55: 189-190.
  9. Koduru, P.R.K. 1979. Metaphase I centromere co-orientation in interchange heterozygotes of pearl millet.             Genet Res. (Camb.) 34: 69-74.
  10. Koduru, P.R.K., Krishna Rao, M. 1980. Spontaneous chlorophyll mutants of Pennisetum americanum:             Genetics and chlorophyll quantities. Theor. Appl. Genet. 56: 137-143.
  11. Koduru, P.R.K. 1980. Chromosome pairing and the meiotic behavior of univalents in synaptic mutants of             pearl millet, Pennisetum americanum (L.) Leeke, Graminae. Genetica 54: 191-197.
  12. Koduru, P.R.K., Murthy, T.G.K., Lakshmi, K.V. 1980. Sectional translocation monosomy in a plat of pearl             millet, Pennisetum americanum (L) Leeke. Chromosoma (Berl.) 78: 365-370.
  13. Koduru, P.R.K., Lakshmi, K.V., Murthy, T.G.K. Chromosome behavior in trisomic plants of pearl millet,             Pennisetum americanum (L) Leeke. Beitr. Biol. Pflanzen. 55: 289-297.
  14. Koduru, P.R.K., Krishna Rao, M. 1981. Cytogenetics of synaptic mutants of higher plants. Theor. Appl. Genet. 59: 197-214.
  15. Lakshmi, K.V., Koduru, P.R.K., Murthy, T.G.K., Rao, M.K. 1982. The effect of trisomy on the meiotic behavior          of interchange complexes in pearl millet, Pennisetum americanum (L) Leeke. Theor. Appl. Genet. 61:       333-335.
  16. Koduru, P.R.K., Murthy, T.G.K., Lakshmi, K.V., Krishna Rao, M. 1982. Analysis of chromosome pairing and      breakage in pearl millet. Genet. Res. (Camb.) 40: 165-174.
  17. Koduru, P.R.K., Grace, R.J., Krishna Rao, M. 1982. Genetic and pigment analysis of a yellow virescent             mutant of pearl millet, Pennisetum americanum (L) Leeke. Beitr. Biol. Pflanzen. 57: 431-438.
  18. Koduru, P.R.K., Krishna Rao, M. Genetics of qualitative traits and linkage studies in pearl millet. Zeitschrift             Pflanzenzuchtg 90: 1-23.
  19. Krishna Rao, M., Aswani Kumari, K., Koduru, P.R.K. 1983. Rate of early seed development in two heterotic          hybrids and their inbred lines of pearl millet, Pennisetum americanum (L) Leeke. Zeitschrift             Pflanzenzuchtg 91: 25-35.
  20. Krishna Rao, M., Subba Rao, B., Koduru, P.R.K. 1984. Genetic analysis of an induced double mutant             system in pearl millet, Pennisetum americanum (L) Leeke. Biol. Zbl. 103: 295-306.
  21. Koduru, P.R.K. Krishna Rao. M. 1984. Cytogenetics of a semi-dwarf mutant in pearl millet, Pennisetum             americanum (L) Leeke. Can. J. Genet. Cytol. 26: 272-278.
  22. Krishna Rao, M., Aswani Kumari, K., Uma Devi, K., Koduru, P.R.K. 1994. Some aspects of cell development   in the young seed of pearl millet, Pennisetum americanum (L) Leeke. Proc. Natl. Sem. Bot. Res., p83-89,   Chandigarh.
  23. Koduru, P.R.K., Krishna Rao. M., Lakshmi, K.V>, Sybenga, J. 1984. Anther development and the orientation       of an interchange quadrivalent in pearl millet. Chromosoma (Berl.) 90: 89-93.
  24. Koduru, P.R.K. 1984. Centromere orientation, reorientation, and segregation in an interchange             quadrivalent during anther development in peal millet. Chromosoma (Berl.) 90: 90-102
  25. Koduru, P.R.K. 1984. Metaphase I orientation of chain forming interchange quadrivalents - a theoretical             consideration. Genetics 108: 707-718.
  26. Koduru, P.R.K. Grace, R.J., Krishna Rao, M. 1985. Karyotype, heterochromatin content and meiotic features           of Poecilocera picta (Orthoptera, Acrididae). Genetica 67: 31-37.
  27. Burns J.P., Koduru, P.R.K. Alonso, M.L., Chaganti, R.S.K. 1986. Analysis of meiotic segregation in a man             heterozygous for two reciprocal translocations using hamster in-vitro fertilization system. Am. J. Hum.   Genet. 38: 954-964.
  28. Chaganti, R.S.K., Balazs, I. Jhanwar, S.C., Murthy, T.G.K., Koduru, P.R.K., Grzrschik, K.-H., Stavnenzer, E.         1986. C-ski, the cellular homologue of the transforming gene of SKV avian retrovirus maps to human             chromosome band 1q22-24, a site of specific translocations in tumors. Cytogenet. Cell Genet. 43: 181-     197.
  29. Doucette, L.A., Koduru, P.R.K., Long, L., Filippa, D. A., Chaganti, R.S.K. 1986. Molecular detection of the             14;18 translocation in non-Hodgkin’s lymphoma. Am. J. Hum. Genet. 38: 197.
  30. Koduru, P.R.K., Filippa, D. A., Richardson, M.E., Jhanwar, S.C., Chaganti, S.C., Koziner, B., Clarkson, B.D.,   Lieberman, P.H., Chaganti, R.S.K. 1987. Cytogenetic and histologic correlation in malignant lymphoma.      Blood 69: 97-102.
  31. Alonso, M.L., Richardson, M.E., Metroka, C.E., Mouradian, J.A., Koduru, P.R.K., Filippa, D.A., Chaganti,             R.S.K. 1987. Chromosome abnormalities in AIDS-related lymphadenopathy. Blood 69: 855-858.
  32. Richardson, M.E., Quanquang, C., Filippa, D.A., Offit, K.O., Hampton, A., Koduru, P.R.K., Jhanwar, S.C.,             Lieberman, P.H., Clarkson, B.D., Chaganti, R.S.K. 1987. Intermediate to high grade histology lymphomas      carrying t(14;18) is associated with additional nonrandom chromosome changes. Blood 70: 444-447.
  33. Chaganti, R.S.K., Koduru, P.R.K. 1987. Patterns of chromosome breakage in non-Hodgkin’s lymphoma:             significance of gene alteration in tumorigenesis. Cytogenet. Cell Genet. 45: 93-98.
  34. Carroll, P., Morse, M.J., Koduru, P.R.K., Chaganti, R.S.K. 1988. Testicular germ cell tumors in a patient with     Klinefelter syndrome. Urology 31: 72-74.
  35. Koduru, P.R.K., Chaganti, R.S.K. 1988. Congenital chromosome breakage clusters within giemsa light bands             and identifies sites of chromosome instability. Cytogenet. Cell Genet. 49: 269-274.
  36. Koduru, P.R.K., Chaganti, R.S.K. 1989. Meiotic chromosome segregation in human t(11;22)(q23;q11)             carriers: a theoretical consideration. Genome 32: 24-29.
  37. Offit, K., Richardson, M.E., Quanaquang, C., Hampton, A., Koduru, P.R.K., Jhanwar, S.C., Filippa, D.A.,             Lieberman, P.H., Clarkson, B., Chaganti, R.S.K. 1989. Non-random chromosome aberrations are             associated with sites of involvement in non-Hodgkin’s lymphoma. Cancer Genet. Cytogenet. 37: 85-93.
  38. Offit, K., Koduru, P.R.K., Hollis, R., Filippa, D.A., Jhanwar, S.C., Clarkson, B., Chaganti, R.S.K. 1989. 18q21 rearrangement in diffuse large cell lymphoma: incidence and clinical significance. Br. J. Haematol. 72:             178-193.
  39. Koduru, P.R.K., DiCostanzo, D., Jhanwar, S.C. 1989. Nonrandom cytogenetic changes characterize Merkel             cell carcinoma. Dis. Mar. 7: 153-161.
  40. Koduru, P.R.K., Offit, K., Jhanwar, S.C. 1989. Molecular analysis of structural chromosome changes             affecting chromosome band 11q23. Dis. Mar. 7: 145-152.
  41. Koduru, P.R.K. Offit, K., Filippa, D.A. 1989. Molecular analysis of breaks in BCL-1 proto-oncogene in B-cell       lymphomas with abnormalities of 11q13. Oncogene 4: 929-934.
  42. Koduru, P.R.K., Offit, K., Filippa, D.A., Lieberman, P.H., Jhanwar, S.C. 1989. Cytogenetic and molecular             genetic analysis of abnormal cells in Hodgkin’s disease. Cancer Genet. Cytogenet. 43: 109-119.
  43. Sun, T., Susin, M., Desner, M., Pergolezzi, R., Cuomo, J., Koduru, P. 1990. The clonal origin of two cell             populations in Richter’s syndrome. Hum. Pathol. 21: 722-728.
  44. Chaganti, R.S.K., Koduru, P.R.K., Chakraborty, R., Jones, W.B. 1990. Genetic origin of trophoblastic             carcinoma. Cancer Res. 50: 6330-6333.
  45. Koduru, P.R.K. 1991. Molecular structure of double reciprocal translocations: significance in B-cell             lymphomagenesis. Oncogene 6: 145-148.
  46. Koduru, P.R.K., Goh, J.C., Allen, S., karp, L., Jasti, H., DeMarco, L., Lichtman, S.M. 1991. Different patterns           of chromosome and molecular breakage in classic Ph1 chronic myelogenous leukemias (CMLs) and    variant Ph1 CMLs. Hematol Pathol. 5: 57-66.
  47. Sun, T., Cohen, N.S., Marino, J., Koduru, P., Cuomo, J., Henshall, J. 1991. CD3+, CD4-, CD8- large             granular T-cell lympho-proliferative disorder. Am. J. Hematol. 37: 173-178.
  48. Foti, A., Ahuja, H.G., Allen, S., Koduru, P., Schuster, M.W., Schulman, P., Bar-Eli, M., Cline, M.J. 1991.             Correlation between molecular and clinical events in the evolution of CML to blast crisis. Blood 77: 2441-   2444.
  49. Sun, T., Susin, M., Koduru, P., Coffey Jr. E.L., Weiss, R., Dittmar, K., Goh, J., Brody, J. 1991. Extranodal             blast crisis in chronic myelogenous leukemia. Demonstration of T-cell lineage and Philadelphia             chromosome in a paraspinal tumor. Cancer 68: 605-610.
  50. Koduru, P.R.K., Goh, J.C., Broome, J.D. 1992. Novel restriction fragment length polymorphism in the cellular             oncogene SEA. Hematol. Pathol. 6: 71-78.
  51. Sun, T., Schulman, P., Kolitz, J., Susin, M., Brody, J., Koduru, P., Muse, W., Hombal, S., Teichberg, S.,             Broome, J. 1992. A study of lymphoma of large granular lymphocytes with modern modalities: Report of         two cases and review of literature. Am. J. Hematol. 40: 135-145.
  52. Sun, T., Brody, J., Koduru, P., Vinciguerra, V., Weiselberg, L., Marino, J., Chaudhri, F., Pappas, J. Erickson,             R. 1992. Study of the major phenotype of the large granular T-cell lympho-proliferative disorder. Am. J.          Clin. Pathol. 98: 516-521.
  53. Sun, T., Susin, M., Koduru, P., Dittmar, K., Yamnopoulos, K., Mahapatro, D., Rogers, C. 1992. Phenotyping             and genotyping of composite lymphoma with KI-1 component. Hematol. Pathol. 6: 179-192.
  54. Lichtman, S., Brody, J., Kaplan, M., Susin, M., Koduru, P., Goh, J.C. 1993. Hodgkin’s disease and non-            Hodgkin’s lymphoma in an HIV positive patient. Leukemia Lymphoma 9: 393-398.
  55. Koduru, P., Susin, M., Schulman, P., Cattell, D., Goh, J., Karp, L., Broome, J.D. 1993. Phenotypic and             genotypic characterization of Hodgkin’s disease. Am. J. Hematol. 44: 117-124.
  56. Koduru, P.R.K., Lichtman, S.M., Smilari, T.F., Sun, T., Hall, W, Chiorazzi, N. Goh, J., Karp, L., Hassimoto, S.,        Broome, J.D. 1993. Serial phenotypic and genotypic studies in Richter’s syndrome: Demonstration of             lymphomagenesis through de-differentiation in chronic lymphocytic leukemia cells. Br. J. Haematol. 85:       613-616.
  57. Koduru, P.R.K., Lichtman, S.M., Broome, JD., Goh, J.C., Pergolizzi, R., Schuster, M., Schulman, P. 1993.             Molecular analysis of a variant t(9;22;11)(q34;q11;q13) reveals the translocation of the 3’-part of bcr to         11q23. Oncogene 8: 3239-3247.
  58. Sun, T., Brody, J., Susin, M., Marino, J., Teichberg, S., Koduru, P., Hall, W.W., Urmacher, C., Hajdu, S.H.             1993. Aggressive natural killer cell lymphoma/leukemia. A recently recognized clinicopathologic entity. Am. J. Sugr. Pathol. 17: 1289-1299.
  59. Morzek, K. Arthur, D.C., Karakousis, C.P., Koduru, P.R.K., Le Beau, M.L., et al., 1995. Der(16)t(1;16) is a             nonrandom secondary chromosome aberration in many types of human neoplasia, including myxoid             liposarcoma, rhabdomyosarcoma and Philadelphia chromosome-positive acute lymphoblastic leukemia.         Int. J. Oncol. 6: 531-538.
  60. Koduru, P.R.K., Susin, M., Kolitz, J., Soni, M., Teichberg, T., Siques, M.J., Sun, T., Amorosi, E., Budman,             D.R. 1995. Morphological, ultrastructural, and genetic characterization of an unusual T-cell lymphoma in   a patient with sinus histiocytosis with massive lymphadenopathy. Am. J. Hematol. 48: 192-200.
  61. Gong, J.Z., Zhou, H., Hu, Z., Schulman, P., Vinciguerra, V., Broome, J.D., Koduru, P.R.K. 1995. Absence of         somatic changes in p21 gene in non-Hodgkin’s lymphoma and chronic myelogenous leukemia. Hematol.         Pathol. 9: 171-177.
  62. Koduru, P.R.K., Zariwala, M. Soni, M., Gong, J.Z., Xiong, Y., Broome, J.D. 1995. Deletion of CDK4 inhibitor           genes p15 and p16 in non-Hodgkin’s lymphoma. Blood 86: 2900-2905.
  63. Brody, J., Allen, S., Schulman, P., Sun, T., Chan, W.C., Friedman, H.D., Teichberg, S., Koduru, P.R.K., Cone,   R.W., Loughran, Jr, T.P. 1995. Acute agranular CD4-positive natural killer cell leukemia. Cancer 75:             2464-2483.
  64. Soni, M., Brody, J., Allen, S., Schulman, P., Kolitz, J., Rai, K., Broome, J.D., Koduru, P.R.K. 1996. Clinical             and morphological features of cases of trisomy 13 in acute non-lymphocytic leukemia. Leukemia 10: 619-     623.
  65. Sun, T., Dittmar, K., Koduru, P., Susin, M., Teichberg, S., Brody, J. 1996. Relationship between hairy cell             leukemia variant and splenic lymphoma with villous lymphocytes: Presentation of a new concept. Am. J. Hematol. 51: 282-288.
  66. Koduru, P., Raju, K., Vadmal, V., Meneges, G., Susin, M., Kolitz, J., Broome, J. 1997. Correlation between             mutation in P53, p-53 expression, cytogenetic, histologic type and duration of survival in patients with B-            cell non-Hodgkin’s lymphoma. Blood 90: 4078-4091.
  67. Morzek, K., Heinonen, K., Lawrence, D., Carroll, A,.J., Koduru, P.R.K., Rao, K.W., Strout, M.P., Mutchson,       R.E., Moore, J.O., Mayer, R.J., Schiffer, C.A., Bloomfield, C.D. 1997. Adult patients with de novo acute       myeloid leukemia and t(9;11)(p22;q23) have a superior outcome to patients with other translocations involving band 11q23. A Cacner and Leukemia Group B study. Blood 90: 4532-4538.
  68. Sun, T., Susin, M., Tomao, F.T., Brody, J., Koduru, P., Hajdu, S.H. 1997. Histiocyte-rich B-cell lymphoma.             Hum. Pathol. 28: 1321-1324.
  69. Vadmal MS, Smilari TF, Brody JP, Koduru P, Hajdu SI. 1998. Cytodiagnosis of primary effusion lymphoma. A case report. Acta Cytol., 42: 374-376.
  70. Sun T, Susin M, Brody J, Tack K, Marsh J, Teichberg S, Koduru P. Schwartz, P. 1998. T-cell lymphom associated with natural killer-like T-cell reaction. Am J Hematol., 57: 331-337.
  71. Quain L., Gong, J.Z., Liu, J., Broome, J.D., Koduru, P. 1999. Cyclin-D2 promoter disrupted by t(12;22)             (p13;q11) during transformation of chronic lymphocytic leukemia (CLL) to non-Hodgkin’s lymphoma. Br. J. Haematol. 106: 477-485.
  72.  Mrozek K, Prior TW, Edwards C, Marcucci G, Carroll AJ, Snyder PJ, Koduru PRK, Theil KS, Pattenati MJ, Archer KJ, Caliguiri MA, Vardiman JW, Kolitz JE, Larson RA, Bloomfield CD. Comparison of cytogenetic and molecular genetic detection of t(8;21) and inv(16) in a prospective series of adults with de novo acute myeloid leukemia: A cancer and leukemia group B study. J Clin Oncol 19: 2482-2492, 2001.
  73.  Peng H, Shen N, Qian L, Koduru P, Goodwin LO, Iss J-P, Broome JD. Hypermethylation of CpG islands in mouse asparagine synthetase gene: Relationship to asparaginase sensitivity in lymphoma cells. Partial methylation in aging normal cells. Br J Cancer, 85: 930-935, 2001.
  74. Demiroglu A, Steer JE, Heath C, Taylor K, Bentley M, Allen SL, Koduru P, Brody JP, Hawson G, Rodwell R, Doody M-L, Carnicero F, Reiter A, Goldman JM, Melo JV, Cross NCP. The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins. Blood, 98: 3778-3783, 2001.
  75. Byrd JC, Mrozek K, Dodge RK, Carroll AJ, Edwards CG, Arthur DC, Pettenati MJ, Patil SR, Rao KW, Watson MS, Koduru PR, Moore JO, Stone RM, Mayer RJ, Feldman EJ, Davery FR, Schiffer CA, Larson RA, Bloomfield CD; Cancer and Leukemia Group B (CALGB 8461). Pretreatment cytogenetics abnormalities are predictive of induction success, cumulative incidence of relapse, and ovrall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461). Blood 100: 4325-4336. 2002.
  76. Byrd, JC, Mrojek, K, Carroll AJ, Pettenati MJ, Arthur DC, Koduru P, Bloomfiedl CD. Repetitive cycles of high-dose cytarabine benefits patients with acure myeloid leukemic and inv(16)(p13q22): Results from Cancer and Leukemia Group B (CALBG 8461). 2004. J Clin Oncol. 22: 1087-1094, 2004.
  77. Marcuccu G, Mrozek K, Ruppert AS, Archer KJ, Pettenati MJ, Heerema NA, Carroll AJ, Koduru PRK, Kolitz JE, Sterline LJ, Edwards CG, Anastasi J, Larson RA, Bloomfield CD. Abnormal cytogenetics at date of morphologic complete remission predicts short overall and disease-free survival, and higher relapse rate in adult acute myeloid leukemia: results from Cancer and Leukemia Group B study 8461. J. Clon. Oncol. 22: 2410-2418, 2004.
  78. Farag SS, Ruppert AS, Mrozek K, Mayer RJ, Stone RM, Carroll AJ, Powell BL, Moore JO, Pettenati MJ, Koduru PRK, Stamberg J, Baer MR, Block, AMW, Vardiman JW, Kolitz JE, Schiffer CA, Larson RA, Bloomfield CD. Outcome of induction and postremission therapy in younger adults with acute myeloid leukemia with normal karyotype: A cancer and Leukemia Group B study. J Clin. Oncol. 23: 482-493, 2005
  79. Messmer BT, Messmer D, Allen SL, Kolitz J, Kuldaker P, Cesar D, Murphy EJ, Koduru P, Ferrarini M, Zupo S, Cutrona G, Damle RN, Wasil, T, Rai KR, Hellerstein MK, Chiorazzi N. Invivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells. J. Clin. Invest. 115: 755-764, 2005.
  80. Grand FH, Koduru P, Cross NCP, Allen SL. NUP98-LEGDF fusion and t(9;11) in transformed chronic myeloid leukemia. Leuk. Research 29: 1469-1472, 2005.
  81. Farag SS, Archer KJ, Mrozek K, Ruppert AS, Carroll AJ, Vardiman JW, Pettenati MJ, Baer MR, Qumsiyeh MB, Koduru PR, Ning Y, Mayer RJ, Stone RM, Larson RA, Bloomfield CD. Pretreatment cytogenetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years of age and older with acute myeloid leukemia: results from Cancer and Leukemia Group B 8461. Blood 108: 73-73, 2006.
  82. Li L, Gupta S, Bashir T, Koduru PR, Brody J, Allen SL. Serial cytogenetic alterations resulting in transformation of a low-grade follicular lymphoma to Burkitt lymphoma. Cancer Genet Cytogenet. 170: 140-146, 2006.
  83. Langer C, Radmacher MD, Ruppert AS, Whitman SP, Paschka P, Mrózek K, Baldus CD, Vukosavljevic T, Liu CG, Ross ME, Powell BL, de la Chapelle A, Kolitz JE, Larson RA, Marcucci G, Bloomfield CD; Cancer and Leukemia Group B (CALGB). High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CALGB) study.. Blood 111: 5371-5379, 2008.
  84. Mrózek K, Carroll AJ, Maharry K, Rao KW, Patil SR, Pettenati MJ, Watson MS, Arthur DC, Tantravahi R, Heerema NA, Koduru PR, Block AW, Qumsiyeh MB, Edwards CG, Sterling LJ, Holland KB, Bloomfield CD. Central review of cytogenetics is necessary for cooperative group correlative and clinical studies of adult acute leukemia: the Cancer and Leukemia Group B experience. Int J Oncol. 33: 239-244, 2008.
  85. Heerema NA, Byrd JC, Dal Cin PS, Dell' Aquila ML, Koduru PR, Aviram A, Smoley SA, Rassenti LZ, Greaves AW, Brown JR, Rai KR, Kipps TJ, Kay NE, Van Dyke DL; Chronic Lymphocytic Leukemia Research Consortium. Stimulation of chronic lymphocytic leukemia cells with CpG oligodeoxynucleotide gives consistent karyotypic results among laboratories: a CLL Research Consortium (CRC) Study. Cancer Genet Cytogenet. 203: 134-140. 2010.
  86. Smoley SA, Van Dyke DL, Kay NE, Heerema NA, Dell' Aquila ML, Dal Cin P, Koduru P, Aviram A, Rassenti L, Byrd JC, Rai KR, Brown JR, Greaves AW, Eckel-Passow J, Neuberg D, Kipps TJ, Dewald GW.
  87. Standardization of fluorescence in situ hybridization studies on chronic lymphocytic leukemia (CLL) blood and marrow cells by the CLL Research Consortium. Cancer Genet Cytogenet. 203: 141-148, 2010
  88. Tirado CA, Chen W, Huang LJ, Laborde C, Hiemenz MC, Valdez F, Ho K, Winick N, Lou Z, Koduru P. Novel JAK2 rearrangement resulting from a t(9;22)(p24;q11.2) in B-acute lymphoblastic leukemia. Leuk Res. 34: 1674-1676, 2010.
  89. Kritharis A, Brody J, Koduru P, Teichberg S, Allen SL. Acute basophilic basophilic leukemia associated with loss of gene ETV6 and protean complications. J Clin Oncol 29: 623-626, 2011.
  90. Chu CC, zhang L, Dhayalan A, Agagnina BM, Magil AR, Fraher G, Didier S, Johnson LP, Kennedy WJ, Damle RN, Yan X-J, Patten PEM, Teichberg S, Koduru P, Kolitz JE, Allen SL, Rai, KR, Chiorazzi N. Torgue teno virus 10 isolated by genome amplification technique from a patient with concomitant chronic lymphocytic leukemia and polycythemia vera. Mol Med.17: 1338-1348, 2011.
  91. Tirado CA, Gotway G, Torgbe E, Iyer S, Dallaire S, Appleberry T, Suterwala M, Garcia R, Valdez F, Patel S, Koduru P. Recombinant chromosome 7 in a mosaic 45,X/47,XXX patient. Am J Med Genet A. 158A; 206-214, 2012.
  92. Walker A, Mrózek K, Kohlschmidt J, Rao KW, Pettenati MJ, Sterling LJ, Marcucci G, Carroll AJ,. Bloomfield CD, Crawford J, Bigner SH, Budman DR, Koduru PR, Bloomfield CD, Heerema NA, Levine EG, Block AW, Burstein HJ, Tantravahi R, Dal Cin P, Bartlett NL, Watson MS, Crawford EC, Garcia-Heras J, Hurd DD, Pettenati MJ, Vaena DA, Patil SR, Kindler HL, Le Beau MM, Peterson BA, Arthur DC, Nattam S, Bader PI, Graziano SL, Stein CK, Parker BA, Bernstein R, Edelman MJ, Testa JR, Lister J, Diggans GR, Diasio R, Carroll AJ, Dragnev K, Wurster-Hill DH, Grunberg SM, Tang M, Roberts JD, Jackson-Cook C, Rafla S, Verma RS, Freter CE, Miles JH, Shea TC, Rao KW, Sikov W, Padre-Mendoza T, Niell HB, Tharapel SA, Ganti A, Sanger WG, Ryan C, Richkind KE, Grubbs SS, Borgaonkar DS, Van Echo D, Richkind KE. New recurrent balanced translocations in acute myeloid leukemia and myelodysplastic syndromes: cancer and leukemia group B 8461. Genes Chromosomes Cancer. 52(4):385-401,2013
  93. Wei Y, Zou Z, Becker N, Anderson M, Sumpter R, Xiao G, Kinch L, Koduru P, Christudass CC, Veltri RW, Grishin NV, Peyton M, Minna J, Bhagat G, Levine B. EGFR-mediated phosphorylation of Beclin-1 in autophagy suppression, tumor progression and tumor chemoresistance. Cell, 154: 1269-1284, 2013.
  94. Kumar KR, Koduru P, Timmons C, Monaghan S, Cavalier ME, Luu HS. Myelodysplastic syndrome (MDS)-associated cytogenetic abnormalities in pediatric chronic myelogenous leukemia. Pediatr Blood Cancer , 2013.
  95. Owusu-Brackett N, Johnson R, Schindel DT, Koduru P, Cope-Yokoyama S. A novel ALK rearrangement in an inflammatory myofibroblastic tumor in a neonate. Cancer Genet 206: 353-356, 2013.
  96. Dang DN, Morris HD, Feusner JH, Koduru P, Wilson K, Timmons CF, Cavalier M, Luu HS. Therapy-induced secondary acute myeloid leukemia with t(11;19)(q23;p13.1) in a pediatric patient with relapsed acute promyelocytic leukemia. J Pediatr Hematol Oncol. 2014 Nov;36(8):e546-8. doi: 10.1097/MPH.0000000000000183.
  97. Wang L, Peters JM, Fuda F, Li L, Karandikar NJ, Koduru P, Wang HY, Chen W. Acute megakaryoblastic leukemia associated with trisomy 21 demonstrates a distinct immunophenotype. Cytometry B Clin Cytom. 2014 Oct 31. doi: 10.1002/cyto.b.21198.
  98. Kim J, Bu L, Koduru PR, Wilson KS, Fuda FS, Kumar KR, Timmons CF, Slone TL, Luu HS. Novel r(2)(p25q31) Cytogenetic Abnormality in a Pediatric Patient With Acute Leukemia of Ambiguous Lineage. Pediatr Dev Pathol. 2014 Dec 1.
  99. Kasten J, Chen W, Fuda F, Koduru P, Monaghan SA. “Diffuse large B-cell lymphoma with prominent cytoplasmic vacuoles involving peripheral blood, bone marrow and cerebrospinal fluid (2014).” Case Reports with Multiple Choice Questions, BloodMed.Com.
  100. Li L, Puliyappadamba VT, Chakraborty S, Rehman A, Vemireddy V, Saha D, Souza RF, Hatanpaa KJ, Koduru P, Burma S, Boothman DA, Habib AA. EGFR wild type antagonizes EGFRvIII-mediated activation of Met in glioblastoma. Oncogene 34: 129-134, 2015.
  101.  Dennis J, Parsa R, Chau D, Koduru P, Peng Y, Fang Y, MD, PhD, Sarode VR. Quantification of Human Epidermal Growth Factor Receptor 2 Immunohistochemistry using the Ventana Image Analysis System: Correlation with Gene Amplification by Fluorescence in Situ Hybridization: The importance of instrument validation for achieving high (>95%) concordance rate . Am J Surg Path 2015.
  102. Kumar KR, Chen W, Koduru PR, Luu HS. Myeloid and lymphoid neoplasm with abnormalities of FGFR1 presenting with trilineage blasts and RUNX1 rearrangement: a case report and review of literature. Am J Clin Pathol. 2015 May;143(5):738-748.
  103.  Witkiewicz AK, McMillan EA, Balaji U, Baek G, Lin WC, Mansour J, Mollaee M, Wagner KU, Koduru P, Yopp A, Choti MA, Yeo CJ, McCue P, White MA, Knudsen ES. Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets. Nat Commun. 2015 Apr 9;6:6744. doi: 10.1038/ncomms7744.
  104. Hatanpaa KJ, Fuda F, Koduru P, Young K, Lega B, Chen W. Lymphomatosis Cerebri: A Diagnostic Challenge. JAMA Neurol. 2015 Jul 6.
  105. Koduru PR, Chen W, Garcia R, Fuda F. Acquisition of a t(11;14)(q13;q32) in clonal evolution in a follicular lymphoma with a t(14;18)(q32;q21) and t(3;22)(q27;q11.2). Cancer Genet. 2015 Mar 18

 

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