Consolato Maria Sergi
Consolato Maria Sergi
  • :+1-780-407-7951

Department of Pediatrics
University of Alberta


  1. Fellowship Examination in Pathology, Royal College of Canada (May 2013) Royal College of Medical Council of Canada Evaluating Examination / Examen d’évaluation du Conseil médical du Canada Royal College of Physicians and Surgeons of Canada (Nov 2009) / Conseil médical du Canada (Nov 2009)
  2. MSc Public Health / MSc de la santé publique Univ. Med. Inform. and Technology, Hall i.T., Austria (Oct 2005 – Jul 2007)
  3. University Personal Professorship (Habilitation), “Higher PhD Level” in Pathology (Venia docendi) Associate Professorships (U.S.A./Canada) Medical University of Innsbruck, Austria (Nov 2004)
  4. Pathology Board Examination / Commission d'examen de pathologie. German Medical Council, Baden Württemberg, Germany (Oct 2001)



Perinatal & Pediatric Pathologist, Full Prof. Pathology & Adj. Prof. Pediatrics (Canada) / Pathologiste pediatrique et Professor titulaire de Pathologie (Canada). Pediatric Pathologist and Assoc. Professor of Pathology (Austria) Mar/2004 – Jul/2008 Medical University of Innsbruck, Tyrol, Austria. His disciplines includes Translational Research, Gastrointestinal, Heart, and Liver Pathology. His Current Research Themes:

  1. Histologic and molecular phenotyping of medical diseases
  2. Investigating animal models
  3. Congenital heart diseases and cholangiopathies of liver


Research Interest

Molecular Pathology and Mechanisms of Gastrointestinal, Liver and Cardiac Diseases.


Professional Activities:

2010 “Paul Revere Award”- Young Scientist for Career - Ass. Clin. Scient.
2009 “Society of Obstetrics and Gynecology of Canada” – Best Proposal Canadian Foundation for Women’s Health, Ottawa, ON, Canada
2004 “Tyrolean Perinatal Program” Foundation, Founder and Organizer
2002 “German Society of Pathology” Bursary, 86th Annual Meeting
2001 “European Assoc. Study of the Liver” Young Investigator Bursary
Sep 1989 / Oct 1993 Postgraduate Residency in Pediatrics (Italy) & Fellowship in Ped. Pathology “G. Gaslini” Children’s Hosp., Univ. of Genoa, Italy
Dec/1993 – Jun/1994 Post-Doc Molecular-Biology Fellowship (Italy) “G. Fornaroli” Hospital, Univ. of Milan, Italy
Jul/1994 – Oct/2001 Postgraduate Residency in Human Pathology (Germany) Inst. of Pathology, Univ. of Heidelberg, Germany



  1. Abou Zeinab R, Wu H, Sergi C, Leng RP. Residues 240-250 in the C-Terminus of the Pirh2 Protein Complement the Function of the RING Domain in Self-Ubiquitination of the Pirh2 Protein. PLoS One. 2013 Dec 18;8(12):e82803. doi: 10.1371/journal.pone.0082803. eCollection 2013. PubMed PMID: 24367557; PubMed Central PMCID: PMC3867404.
  2. Alipour M, Lou Y, Zimmerman D, Bording-Jorgensen MW, Sergi C, Liu JJ, Wine E. A Balanced IL-1β Activity Is Required for Host Response to Citrobacter rodentium Infection. PLoS One. 2013 Dec 2;8(12):e80656. doi: 10.1371/journal.pone.0080656. eCollection 2013. PubMed PMID: 24312491; PubMed Central PMCID: PMC3846666.
  3. Solez K, Bernier A, Crichton J, Graves H, Kuttikat P, Lockwood R, Marovitz WF, Monroe D, Pallen M, Pandya S, Pearce D, Saleh A, Sandhu N, Sergi C, Tuszynski J, Waugh E, White J, Woodside M, Wyndham R, Zaiane O, Zakus D. Bridging the gap between the technological singularity and mainstream medicine: highlighting a course on technology and the future of medicine. Glob J Health Sci. 2013 Sep 9;5(6):112-25. doi: 10.5539/gjhs.v5n6p112. PubMed PMID: 24171879.
  4. Abdualmjid RJ, Sergi C. Hepatotoxic botanicals - an evidence-based systematic review. J Pharm Pharm Sci. 2013;16(3):376-404. PubMed PMID: 24021288.
  5. Pelletier JS, LaBossiere J, Dicken B, Gill RS, Sergi C, Tahbaz N, Bigam D, Cheung PY. Low-dose vasopressin improves cardiac function in newborn piglets with acute hypoxiareoxygenation. Shock. 2013 Oct;40(4):320-6. doi:10.1097/SHK.0b013e3182a4284e. PubMed PMID: 23856923.
  6. Metcalfe PD, Bascom A, Sergi C. Mimickers and tumours in the lower urinary tract: Do we need more efficient vigilance? Can Urol Assoc J. 2013 May-Jun;7(5-6):E421-5. doi: 10.5489/cuaj.1386. PubMed PMID: 23826055; PubMed Central PMCID: PMC3699090.
  7. Broome M, Vial Y, Jacquemont S, Sergi C, Kamnasaran D, Giannoni E. Complete Maxillo-Mandibular Syngnathia in a Newborn with Multiple Congenital Malformations. Pediatr Neonatol. 2013 Jun 15. pii: S1875-9572(13)00081-8. doi:10.1016/j.pedneo.2013.04.009. [Epub ahead of print] PubMed PMID: 23778189.
  8. Al-Bahrani R, Abuetabh Y, Zeitouni N, Sergi C. Cholangiocarcinoma: risk factors, environmental influences and oncogenesis. Ann Clin Lab Sci. 2013 Spring;43(2):195-210. Review. PubMed PMID: 23694797. C. Sergi, MD, PhD, MPH Edmonton, AB, Canada, 2014-03-25 7/26
  9. Valtuille L, Paterson I, Kim DH, Mullen J, Sergi C, Oudit GY. A case of lamin A/C mutation cardiomyopathy with overlap features of ARVC: a critical role of genetic testing. Int J Cardiol. 2013 Oct 9;168(4):4325-7. doi:10.1016/j.ijcard.2013.04.177. Epub 2013 May 16. PubMed PMID: 23684604.
  10. Liu JJ, Davis EM, Wine E, Lou Y, Rudzinski JK, Alipour M, Boulanger P, Thiesen AL, Sergi C, Fedorak RN, Muruve D, Madsen KL, Irvin RT. Epithelial cell extrusion leads to breaches in the intestinal epithelium. Inflamm Bowel Dis. 2013 Apr;19(5):912-21. doi: 10.1097/MIB.0b013e3182807600. PubMed PMID: 23511029.
  11. Sergi C, Gekas J, Kamnasaran D. Recurrent anencephaly: a case report and examination of the VANGL1 and FOXN1 genes. Fetal Pediatr Pathol. 2013 Jul;32(4):293-7. doi: 10.3109/15513815.2012.754526. Epub 2013 Jan 10. PubMed PMID: 23301910.
  12. Kulkarni KP, Sergi C. Appendix carcinoids in childhood: long-term experience at a single institution in Western Canada and systematic review. Pediatr Int. 2013 Apr;55(2):157-62. doi: 10.1111/ped.12047. Review. PubMed PMID: 23279208.
  13. Zeinab RA, Wu H, Sergi C, Leng R. UBE4B: A Promising Regulatory Molecule in Neuronal Death and Survival. Int J Mol Sci. 2012 Dec 10;13(12):16865-79. doi: 10.3390/ijms131216865. PubMed PMID: 23222733; PubMed Central PMCID: PMC3546727.
  14. Kulkarni K, Desai S, Grundy P, Sergi C. Infantile myofibromatosis: report on a family with autosomal dominant inheritance and variable penetrance. J Pediatr Surg. 2012 Dec;47(12):2312-5. doi: 10.1016/j.jpedsurg.2012.09.046. PubMed PMID: 23217896.
  15. Gekas J, Sergi C, Kamnasaran D. Molecular prenatal diagnosis of a sporadic alobar holoprosencephalic fetus: genotype-phenotype correlations. J Prenat Med. 2012 Jul;6(3):36-9. PubMed PMID: 23181171; PubMed Central PMCID: PMC3503521.
  16. Loh J, El-Hakim H, Sergi C, Fiorillo L. Branchiooculofacial syndrome and bilateral ectopic thymus: report of a family. Pediatr Dermatol. 2012 Nov-Dec;29(6):759-61. doi: 10.1111/j.1525-1470.2012.01877.x. PubMed PMID:23106675.
  17. Forsman CL, Ng BC, Heinze RK, Kuo C, Sergi C, Gopalakrishnan R, Yee D, Graf D, Schwertfeger KL, Petryk A. BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization. Dev Biol. 2013 Jan 1;373(1):95-106. doi:10.1016/j.ydbio.2012.10.007. Epub 2012 Oct 24. PubMed PMID: 23103586; PubMed Central PMCID: PMC3508155. C. Sergi, MD, PhD, FRCPC Edmonton, AB, Canada, 2014-03-25 8/26
  18. Johnston J, Al-Bahrani R, Abuetabh Y, Chiu B, Forsman CL, Nagamori S, Leng R, Petryk A, Sergi C. Twisted gastrulation expression in cholangiocellular and hepatocellular carcinoma. J Clin Pathol. 2012 Oct;65(10):945-8. Epub 2012 May 25. PubMed PMID: 22639408.
  19. Chassaing N, Sorrentino S, Davis EE, Martin-Coignard D, Iacovelli A, Paznekas W, Webb BD, Faye-Petersen O, Encha-Razavi F, Lequeux L, Vigouroux A, Yesilyurt A, Boyadjiev SA, Kayserili H, Loget P, Carles D, Sergi C, Puvabanditsin S, Chen CP, Etchevers HC, Katsanis N, Mercer CL, Calvas P, Jabs EW. OTX2 mutations contribute to the otocephaly-dysgnathia complex. J Med Genet. 2012 Jun;49(6):373-9. doi: 10.1136/jmedgenet-2012-100892. Epub 2012 May 10. PubMed PMID: 22577225.
  20. Sergi C, Kulkarni K, Stobart K, Lees G, Noga M. Clear cell variant of embryonal rhabdomyosarcoma: report of an unusual retroperitoneal tumor—case report and literature review. Eur J Pediatr Surg. 2012 Aug;22(4):324-8. doi:10.1055/s-0032-1308714. Epub 2012 May 10. Review. PubMed PMID: 22576307.
  21. Sergi C, Kamnasaran D. PRRX1 is mutated in a fetus with agnathia-otocephaly. Clin Genet 2011 Mar;79(3):293-5. doi: 10.1111/j.1399-0004.2010.01531.x.
  22. Brunner J, Boehler T, Ehemann V, Kassam S, Otto H, Sergi C. Decreased Apoptosis Despite Severe CD4 Depletion in the Thymus of a Human Immunodeficiency Virus-1 Infected Child. Klin Padiatr. 2011 Jan 26.
  23. Turner JM, Wales PW, Nation PN, Wizzard P, Pendlebury C, Sergi C, Ball RO, Pencharz PB. Novel neonatal piglet models of surgical short bowel syndrome with intestinal failure. J Pediatr Gastroenterol Nutr. 2011 Jan;52(1):9-16.
  24. Yu TW, Mochida GH, Tischfield DJ, Sgaier SK, Flores-Sarnat L, Sergi CM, Topcu M, McDonald MT, Barry BJ, Felie JM, Sunu C, Dobyns WB, Folkerth RD, Barkovich AJ, Walsh CA. Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture. Nat Genet. 2010 Nov;42(11):1015-20. Epub 2010 Oct 3.
  25. Sun M, Forsman C, Sergi C, Gopalakrishnan R, O'Connor MB, Petryk A. The expression of twisted gastrulation in postnatal mouse brain and functional implications. Neuroscience. 2010 Aug 25;169(2):920-31. Epub 2010 May 20.
  26. Glueckert R, Rask-Andersen H, Sergi C, Schmutzhard J, Mueller B, Beckmann F, Rittinger O, Hoefsloot LH, Schrott-Fischer A, Janecke AR. Histology and synchrotron radiation-based microtomography of the inner ear in a molecularly confirmed case of CHARGE syndrome. Am J Med Genet A. 2010 Mar;152A(3):665-73.
  27. Stambader JD, Dorn L, Mikuz G, Sergi C. Genetic polymorphisms in dilated cardiomyopathy. Front Biosci. 2010 Jan 1;2:653-76. Review.
  28. Chiu B, Sergi C. Dilated cardiomyopathy: etio-morphologic investigation. Front Biosci. 2010 Jan 1;2:112-6. Review. C. Sergi, MD, PhD, MPH Edmonton, AB, Canada, 2014-03-25 9/26
  29. Corfield A, Meyer P, Kassam S, Mikuz G, Sergi C. SNPs: At the origins of the databases of an innovative biotechnology tool. Front Biosci. 2010 Jan 1;2:1-4. Review.
  30. Meier JJ, Koehler CU, Alkhatib B, Sergi C, Junker T, Klein HH, Schmidt WE, Fritsch H. Beta-cell development and turnover during prenatal life in humans. Eur J Endocrinol. 2010 Mar;162(3):559-68. Epub 2009 Dec 18.
  31. Schmutzhard J, Schwentner I, Glueckert R, Sergi C, Beckmann F, Abraham I, Riechelmann H, Schrott-Fischer A, Mueller B. Pelizaeus Merzbacher disease: morphological analysis of the vestibulo-cochlear system. Acta Otolaryngol. 2009 Dec;129(12):1395-9.
  32. Schmutzhard J, Glueckert R, Bitsche M, Abraham I, Falkeis C, Schwentner I, Riechelmann H, Mueller B, Beckmann F, Sergi C, Schrott-Fischer A. The cochlea in fetuses with neural tube defects. Int J Dev Neurosci. 2009 Nov;27(7):669-76.
  33. Schwentner I, Schmutzhard J, Glueckert R, Charitidi K, Falkeis C, Sergi C, Canlon B, SchrottFischer A. Epidermal growth factor receptor expression in human fetal cochlea with Turner syndrome. Otol Neurotol. 2009 Sep;30(6):858-63.
  34. Geiger R, Treml B, Pinna A, Barnickel L, Prossliner H, Reinstadler H, Pilch M, Hauer M, Walther C, Steiner HJ, Giese T, Wemhoener A, Scholl-Buergi S, Gottardi W, Arnitz R, Sergi C, Nagl M, Loeckinger A. Tolerability of inhaled N-chlorotaurine in the pig model. BMC Pulm Med. 2009 Jul 14;9:33.
  35. Ressler S, Radhi J, Aigner T, Loo C, Zwerschke W, Sergi C. Insulin-like growth factor-binding protein-3 in osteosarcomas and normal bone tissues. Anticancer Res. 2009 Jul;29(7):2579-87.
  36. Nathan BM, Sockalosky J, Nelson L, Lai S, Sergi C, Petryk A. The use of hormonal therapy in pediatric heart disease. Front Biosci. 2009 Jun 1;1:358-75. Review.
  37. Brunner J, Freund M, Prelog M, Binder E, Sailer-Hoeck M, Jungraithmayr T, Huemer C, Sergi C, Zimmerhackl LB. Successful treatment of severe juvenile microscopic polyangiitis with rituximab. Clin Rheumatol. 2009 Aug;28(8):997-9.
  38. Schiesser M, Sergi C, Enders M, Maul H, Schnitzler P. Discordant outcomes in a case of parvovirus b19 transmission into both dichorionic twins. Twin Res Hum Genet. 2009 Apr;12(2):175-9.
  39. Dorn L, Menezes LF, Mikuz G, Otto HF, Onuchic LF, Sergi C. Immunohistochemical detection of polyductin and co-localization with liver progenitor cell markers during normal and abnormal development of the intrahepatic biliary system and in adult hepatobiliary carcinomas. J Cell Mol Med. 2009 Jul;13(7):1279-90. C. Sergi, MD, PhD, FRCPC Edmonton, AB, Canada, 2014-03-25 10/26
  40. Schmutzhard J, Schwentner I, Glueckert R, Sergi C, Beckmann F, Abraham I, Riechelmann H, Schrott-Fischer A, Muller B. Pelizaeus Merzbacher disease: morphological analysis of the vestibulo-cochlear system. Acta Otolaryngol. 2009 Feb 20:1-5.

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