Education

Biography

He is an Associate Professor. 2003.09 − 2007.07, he studied for B. S. in Department of Polymer Science and Engineering, University of Science and Technology of China; 2007.09 − 2012.12, he enrolled in Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS), and received his Ph. D. in January 2013. Now, he serves as Associate Professor in CIAC, CAS.

Research Interest

His research focuses on the developments of (1) exploitations of stimuli-responsive polymers as the matrices of smart nanocarriers, (2) developments of cell-related nanoscale platforms for controlled drug delivery, and (3) regenerative biomaterials. He has published more than 90 pre-reviewed research papers in international academic journals including Biomaterials, Journal of Controlled Release, Chemical Communications, Advanced Healthcare Materials, Biomacromolecules, Polymer Chemistry

Professional Activities:

He has applied over 50 Chinese invention patents, of which more than 20 ones was authorized. Among them, one was awarded as First Prize of Jilin Province Invention Contest (ranked second), and the other one was rated as Excellence Award of Chinese Patent Award (ranked second). In addition, he was honored as Outstanding Paper Award for Young Scholars (Second Award) by National Biomaterials Congress in 2010, Best Poster Award by the First Symposium on Innovative Polymers for Controlled Delivery. (SIPCD 2010) in 2010, Tang Aoqing Chemistry Scholarship by Tang Aoqing Education Foundation of Jilin University in 2011, President Award (Excellence) by Chinese Academy of Sciences in 2012, Graduate National Scholarship by Ministry of Education in 2012, and Jilin Province Natural Science Academic Achievement Award by Science and Technology Association of Jilin Province in 2014. Recently, he is serving as Guest Editor of Current Pharmaceutical Biotechnology (Topic: Polymeric Nanomedicines for Malignancy Therapy, In Press), Polymers (Topic: Functional Polymers for Medical Applications), and Journal of Nanomaterials (Topic: Smart Polymeric Nanocarriers).

Publications

1. Zhao, L.; Ding J.; Xiao, C.*; Chen, X.; Gai, G.; Wang, L., Poly(L-glutamic acid) Microsphere: Preparation and Application in Oral Drug Controlled Release. Acta Chimica Sinica 2015, 73 (1), 60−65.
2. Zhao, L.; Xiao, C.; Ding, J.; Zhuang, X.; Gai, G.; Wang, L.; Chen, X.*, Competitive binding-accelerated insulin release from a polypeptide nanogel for potential therapy of diabetes. Polymer Chemistry 2015, 6 (20), 3807−3815.
3. Zhao, L.; Ding, J.; Xiao, C.; Zhuang, X.; Chen, X.*, Phenylboronic acid-functionalized polypeptide nanogel for glucose-responsive insulin release under physiological pH. Journal of Controlled Release 2015, 213, e69.
4. Zhang, Z.Z.; Jiang, D.; Wang, S.J.; Qi, Y.S.; Ding, J.X.*; Yu, J.K.*; Chen, X.S., Scaffolds drive meniscus tissue engineering. RSC Advances 2015, 5 (95), 77851−77859.
5. Zhang, Z.*; Gu, X.; Sun, D.*; Ding, J.; Li, Q.*; Zhuang, X.; Chen, X., pH-responsive PEGylated doxorubicin for efficient cancer chemotherapy. Journal of Controlled Release 2015, 213, e149.
6. Zhang, Y.; Sun, D.; Ding, J.*; Li, C.; Chang, F.*; Zhuang, X.; Chen, X.; Wang, J.*, Doxorubicin prodrug thermogel as sustained drug reservoir for in situ malignant therapy. Journal of Controlled Release 2015, 213, e126−e127.
7. Zhang, Y.; Ding, J.*; Sun, D.; Sun, H.; Zhuang, X.; Chang, F.*; Wang, J.*; Chen, X., Thermogel-mediated sustained drug delivery for in situ malignancy chemotherapy. Materials Science & Engineering C-Materials for Biological Applications 2015, 49 (0), 262−268.
8. Zhang, Y.; Chen, L.; Ding, J.*; Shen, K.; Yang, M.; Xiao, C.; Zhuang, X.; Chen, X., Self-programmed pH-sensitive polymeric prodrug micelle for synergistic cancer therapy. Journal of Controlled Release 2015, 213, e135−e136.
9. Zhang, Q.; Sun, X.; Ding, J.; He, P.; Liu, Y.; Cheng, H.; Zhou, C.; Meng, X.*, Autoserum: An Optimal Supplement for Bone Marrow Mesenchymal Stem Cells of Liver-Injured Rats. Stem Cells International 2015, 2015, 459580.
10. Zhang, J.; Liu, H.; Ding, J.X.*; Zhuang, X.L.; Chen, X.S.; Li, Z.M.*, Annealing regulates the performance of an electrospun poly(ε-caprolactone) membrane to accommodate tissue engineering. RSC Advances 2015, 5 (41), 32604−32608.
11. Yao, X.; Chen, L.*; Chen, X.; Xie, Z.; Ding, J.; He, C.; Zhang, J.; Chen, X., pH-responsive metallo-supramolecular nanogel for synergistic chemo-photodynamic therapy. Acta Biomaterialia 2015, 25, 162−171.
12. Xu, W.; Li, L.; Lu, S.; Ding, J.*; Xiao, C.; Zhuang, X.; Chen, X., Two-way combination chemotherapy for synergistic tumor capture. Journal of Controlled Release 2015, 213, e113−e114.
13. Xu, W.; Ding, J.*; Xiao, C.; Li, L.; Zhuang, X.; Chen, X.*, Versatile preparation of intracellular-acidity-sensitive oxime-linked polysaccharide-doxorubicin conjugate for malignancy therapeutic. Biomaterials 2015, 54 (0), 72−86.
14. Xu, W.; Ding, J.*; Li, L.; Xiao, C.; Zhuang, X.; Chen, X.*, Acid-labile boronate-bridged dextran-bortezomib conjugate with up-regulated hypoxic tumor suppression. Chemical Communications 2015, 51 (31), 6812−6815.
15. Xiao, C.; Ding, J.; Zhuang, X.; Chen, X.*, PEG-based thermo-responsive poly(β-thioether ester) for ROS-triggered drug delivery. Journal of Controlled Release 2015, 213, e22.
16. Xiao, C.; Ding, J.; Ma, L.; Yang, C.; Zhuang, X.; Chen, X.*, Synthesis of thermal and oxidation dual responsive polymers for reactive oxygen species (ROS)-triggered drug release. Polymer Chemistry 2015, 6 (5), 738−747.
17. Wei, J.*; Guo-Wang, P.; Han, Q.; Ding, J.*; Chen, X., Preparation of antibacterial silver nanoparticle-coated PLLA grafted hydroxyapatite/PLLA composite electrospun fiber. Journal of Controlled Release 2015, 213, e62−e63.
18. Wang, X.; Shan, H.; Wang, J.; Hou, Y.; Ding, J.*; Chen, Q.; Guan, J.; Wang, C.*; Chen, X., Characterization of nanostructured ureteral stent with gradient degradation in a porcine model. International Journal of Nanomedicine 2015, 10, 3055−3064.
19. Wang, J.; Xu, W.; Guo, H.; Ding, J.*; Chen, J.; Guan, J.*; Wang, C., Selective intracellular drug delivery from pH-responsive polyion complex micelle for enhanced malignancy suppression in vivo. Colloids and Surfaces B: Biointerfaces 2015, 135, 283−290.
20. Wang, J.; Xu, W.; Ding, J.*; Lu, S.; Wang, X.; Wang, C.*; Chen, X., Cholesterol-Enhanced Polylactide-Based Stereocomplex Micelle for Effective Delivery of Doxorubicin. Materials 2015, 8 (1), 216−230.
21. Wang, J.; Shen, K.; Xu, W.; Ding, J.; Wang, X.; Liu, T.*; Wang, C.*; Chen, X., Stereocomplex micelle from nonlinear enantiomeric copolymers efficiently transports antineoplastic drug. Nanoscale Research Letters 2015, 10 (1), 206.
22. Wang, J.#; Li, D.#; Li, T.; Ding, J.; Liu, J.*; Li, B.*; Chen, X., Gelatin Tight-Coated Poly(lactide-co-glycolide) Scaffold Incorporating rhBMP-2 for Bone Tissue Engineering. Materials 2015, 8 (3), 1009−1026.
23. Sun, D.; Ding, J.*; Xiao, C.; Chen, J.; Zhuang, X.; Chen, X., Drug Delivery: pH-Responsive Reversible PEGylation Improves Performance of Antineoplastic Agent (Adv. Healthcare Mater. 6/2015). Advanced Healthcare Materials 2015, 4 (6), 786−786.
24. Sun, D.; Ding, J.*; Xiao, C.; Chen, J.; Zhuang, X.; Chen, X., pH-Responsive Reversible PEGylation Improves Performance of Antineoplastic Agent. Advanced Healthcare Materials 2015, 4 (6), 844−855.
25. Song, Z.M.; Shi, B.; Ding, J.X.*; Zhuang, X.L.; Zhang, X.N.; Fu, C.F.*; Chen, X.S., Prevention of postoperative tendon adhesion by biodegradable electrospun membrane of poly(lactide-co-glycolide). Chinese Journal of Polymer Science 2015, 33 (4), 587−596.
26. Song, Z.; Shi, B.; Ding, J.*; Zhuang, X.; Zhang, X.; Fu, C.*; Chen, X., A comparative study of preventing postoperative tendon adhesion using electrospun polyester membranes with different degradation kinetics. Science China-Chemistry 2015, 58 (7), 1159-1168.
27. Shi, B.; Ding, J.*; Zhuang, X.; Chen, X.; Niu, Z.; Fu, C.*, Multifunctional three-dimensional scaffolds for treatment of spinal cord injury. Journal of Controlled Release 2015, 213, e12−e13.
28. Shi, B.; Ding, J.*; Wei, J.*; Fu, C.*; Zhuang, X.; Chen, X., Drug-Incorporated Electrospun Fibers Efficiently Prevent Postoperative Adhesion. Current Pharmaceutical Design 2015, 21 (15), 1960−1966.
29. Shen, K.; Zhang, Y.*; Ding, J.; Zhang, H.*, c(RGDfC)-decorated micelle as nanocarrier for targeting therapeutic of colon cancer. Journal of Controlled Release 2015, 213, e66.
30. Liu, H.; Ding, J.; Wang, J.; Wang, Y.*; Yang, M.; Zhang, Y.; Chang, F.*; Chen, X., Remission of Collagen-Induced Arthritis through Combination Therapy of Microfracture and Transplantation of Thermogel-Encapsulated Bone Marrow Mesenchymal Stem Cells. PLoS ONE 2015, 10 (3), e0120596.
31. Li, Y.; Tian, H.*; Ding, J.; Lin, L.; Chen, J.; Gao, S.; Chen, X.*, Guanidinated Thiourea-Decorated Polyethylenimines for Enhanced Membrane Penetration and Efficient siRNA Delivery. Advanced Healthcare Materials 2015, 4 (9), 1369−1375.
32. Li, X.; Ding, J.*; Wang, J.; Zhuang, X.; Chen, X.*, Biomimetic biphasic scaffolds for osteochondral defect repair. Regenerative Biomaterials 2015, 2 (3), 221−228.
33. Li, C.#; Xu, W.#; Ding, J.*; Zhang, Y.; Wang, J.*; Zhuang, X.; Chen, X., Back Cover: Macromol. Biosci. 3/2015. Macromolecular Bioscience 2015, 15 (3), 438.
34. Li, C.#; Xu, W.#; Ding, J.*; Zhang, Y.; Wang, J.*; Zhuang, X.; Chen, X., Micellization of Antineoplastic Agent to Significantly Upregulate Efficacy and Security. Macromolecular Bioscience 2015, 15 (3), 328−341.
35. Huang, K.; Shi, B.; Xu, W.; Ding, J.*; Yang, Y.; Liu, H.*; Zhuang, X.; Chen, X., Reduction-responsive polypeptide nanogel delivers antitumor drug for improved efficacy and safety. Acta Biomaterialia 2015, 27, 179−193.
36. Han, Q.; Ding, J.*; Zheng, Y.; Zhuang, X.; Chen, X.; Wang, J.*, Hydroxyapatite and vancomycin composited electrospun polylactide mat for osteomyelitis and bone defect treatment. Journal of Controlled Release 2015, 213, e92.
37. Ding, J.#; Li, C.#; Zhang, Y.#; Xu, W.; Wang, J.; Chen, X.*, Chirality-mediated polypeptide micelles for regulated drug delivery. Acta Biomaterialia 2015, 11 (0), 346−355.
38. Chen, J.; Zhang, Y.; Ding, J.; Xiao, C.; Zhuang, X.; Chen, X.*, pH-sensitive polyion complex micelles for tunable intracellular drug delivery. Journal of Controlled Release 2015, 213, e55.
39. Chen, J.#; Ding, J.#; Zhang, Y.; Xiao, C.; Zhuang, X.; Chen, X.*, Polyion complex micelles with gradient pH-sensitivity for adjustable intracellular drug delivery. Polymer Chemistry 2015, 6 (3), 397−405.
40. Chen, J.; Ding, J.*; Xiao, C.; Zhuang, X.; Chen, X.*, Emerging antitumor applications of extracellularly reengineered polymeric nanocarriers. Biomaterials Science 2015, 3 (7), 988−1001.
41. Zhang, Y.B.; Ding, J.X.*; Xu, W.G.; Wu, J.; Chang, F.*; Zhuang, X.L.; Chen, X.S.; Wang, J.C.*, Biodegradable thermogel as culture matrix of bone marrow mesenchymal stem cells for potential cartilage tissue engineering. Chinese Journal of Polymer Science 2014, 32 (12), 1590−1601.
42. Zhang, Y.; Xiao, C.; Li, M.; Ding, J.; Yang, C.; Zhuang, X.; Chen, X.*, Co-delivery of doxorubicin and paclitaxel with linear-dendritic block copolymer for enhanced anti-cancer efficacy. Science China-Chemistry 2014, 57 (4), 624−632.
43. Zhang, Y.; Xiao, C.; Li, M.; Ding, J.; He, C.; Zhuang, X.; Chen, X.*, Core-cross-linked micellar nanoparticles from a linear-dendritic prodrug for dual-responsive drug delivery. Polymer Chemistry 2014, 5 (8), 2801−2808.
44. Zhang, J.#; Liu, H.#; Xu, H.; Ding, J.X.*; Zhuang, X.L.; Chen, X.S.; Chang, F.*; Xu, J.Z.; Li, Z.M.*, Molecular weight-modulated electrospun poly([varepsilon]-caprolactone) membranes for postoperative adhesion prevention. RSC Advances 2014, 4 (79), 41696−41704.
45. Yu, S.#; Ding, J.#; He, C.*; Cao, Y.; Xu, W.; Chen, X., Disulfide Cross-Linked Polyurethane Micelles as a Reduction-Triggered Drug Delivery System for Cancer Therapy. Advanced Healthcare Materials 2014, 3 (5), 752−760.
46. Xiao, C.; Cheng, Y.; Zhang, Y.; Ding, J.; He, C.; Zhuang, X.; Chen, X.*, Side Chain Impacts on pH- and Thermo- Responsiveness of Tertiary Amine Functionalized Polypeptides. Journal of Polymer Science Part A: Polymer Chemistry 2014, 52 (5), 671−679.
47. Sun, D.; Ding, J.*; Xiao, C.; Chen, J.; Zhuang, X.*; Chen, X., Preclinical Evaluation of Antitumor Activity of Acid-Sensitive PEGylated Doxorubicin. ACS Applied Materials & Interfaces 2014, 6 (23), 21202−21214.
48. Shi, B.; Ding, J.*; Liu, Y.; Zhuang, X.; Zhuang, X.; Chen, X.; Fu, C.*, ERK1/2 Pathway-Mediated Differentiation of IGF-1-Transfected Spinal Cord-Derived Neural Stem Cells into Oligodendrocytes. PLoS ONE 2014, 9 (8), e106038.
49. Liu, D.H.; Ding, J.X.*; Xu, W.G.; Song, X.F.*; Zhuang, X.L.; Chen, X.S., Stereocomplex Micelles Based on 4-Armed Poly ( ethylene glycol ) -Polylactide Enantiomeric Copolymers for Drug Delivery. Acta Polymerica Sinica 2014, (9), 1265−1273.
50. Li, Y.; Tian, H.; Xiao, C.; Ding, J.; Chen, X.*, Efficient recovery of precious metal based on Au-S bond and electrostatic interaction. Green Chemistry 2014, 16 (12), 4875−4878.
51. Li, Y.; Tian, H.; Ding, J.; Dong, X.; Chen, J.; Chen, X.*, Thiourea modified polyethylenimine for efficient gene delivery mediated by the combination of electrostatic interactions and hydrogen bonds. Polymer Chemistry 2014, 5 (11),
52. 3598−3607.
53. Ding, J.; Chen, L.; Xiao, C.; Chen, L.; Zhuang, X.; Chen, X.*, Noncovalent interaction-assisted polymeric micelles for controlled drug delivery. Chemical Communications 2014, 50 (77), 11274−11290.
54. Zhao, L.; Xiao, C.; Ding, J.; He, P.; Tang, Z.; Pang, X.; Zhuang, X.; Chen, X.*, Facile one-pot synthesis of glucose-sensitive nanogel via thiol-ene click chemistry for self-regulated drug delivery. Acta Biomaterialia 2013, 9 (5), 6535−6543.
55. Zhao, L.; Ding, J.; Xiao, C.; He, P.; Tang, Z.; Chen, X.*, Phenylboronic acid functionalized polypeptide micelles for glucose-responsive insulin release at physiological pH. Journal of Controlled Release 2013, 172 (1), E110−E110.
56. Zhang, Z.; Ding, J.; Chen, X.; Xiao, C.; He, C.*; Zhuang, X.; Chen, L.*; Chen, X., Intracellular pH-sensitive supramolecular amphiphiles based on host-guest recognition between benzimidazole and beta-cyclodextrin as potential drug delivery vehicles. Polymer Chemistry 2013, 4 (11), 3265−3271.
57. Zhang, Y.; Xiao, C.; Li, M.; Chen, J.; Ding, J.; He, C.; Zhuang, X.; Chen, X.*, Co-delivery of 10-Hydroxycamptothecin with Doxorubicin Conjugated Prodrugs for Enhanced Anticancer Efficacy. Macromolecular Bioscience 2013, 13 (5), 584−594.
58. Zhang, A.; Zhang, Z.; Shi, F.; Xiao, C.; Ding, J.; Zhuang, X.*; He, C.; Chen, L.*; Chen, X., Redox-Sensitive Shell-Crosslinked Polypeptide-block-Polysaccharide Micelles for Efficient Intracellular Anticancer Drug Delivery. Macromolecular Bioscience 2013, 13 (9), 1249−1258.
59. Zhang, A.; Zhang, Z.; Shi, F.; Ding, J.; Xiao, C.; Zhuang, X.*; He, C.; Chen, L.*; Chen, X., Disulfide crosslinked PEGylated starch micelles as efficient intracellular drug delivery platforms. Soft Matter 2013, 9 (7), 2224−2233.
60. Yu, S.; He, C.*; Ding, J.; Cheng, Y.; Song, W.; Zhuang, X.; Chen, X., pH and reduction dual responsive polyurethane triblock copolymers for efficient intracellular drug delivery. Soft Matter 2013, 9 (9), 2637−2645.
61. Xiao, C.; Ding, J.; Li, Y.; Zhuang, X.; He, C.; Chen, X.*, Physical interaction induced self-assembly of glycopeptide and doxorubicin at physiological pH as promising hepatoma-targeted nanomedicine. Journal of Controlled Release 2013, 172 (1), E23−E24.
62. Li, M.; Tang, Z.; Sun, H.; Ding, J.; Song, W.; Chen, X.*, pH and reduction dual-responsive nanogel cross-linked by quaternization reaction for enhanced cellular internalization and intracellular drug delivery. Polymer Chemistry 2013, 4 (4), 1199−1207.
63. Li, D.#; Sun, H.#; Ding, J.*; Tang, Z.*; Zhang, Y.; Xu, W.; Zhuang, X.; Chen, X., Polymeric topology and composition constrained polyether-polyester micelles for directional antitumor drug delivery. Acta Biomaterialia 2013, 9 (11), 8875−8884.
64. Han, J.#; Ding, J.#; Wang, Z.; Yan, S.; Zhuang, X.; Chen, X.; Yin, J.*, The synthesis, deprotection and properties of poly(γ-benzyl-L-glutamate). Science China-Chemistry 2013, 56 (6), 729−738.
65. Ding, J.; Zhao, L.; Li, D.; Xiao, C.*; Zhuang, X.*; Chen, X., Thermo-responsive "hairy-rod" polypeptides for smart antitumor drug delivery. Polymer Chemistry 2013, 4 (11), 3345−3356.
66. Ding, J.; Xu, W.; Zhang, Y.; Sun, D.; Xiao, C.*; Liu, D.; Zhu, X.*; Chen, X.*, Self-reinforced endocytoses of smart polypeptide nanogels for "on-demand" drug delivery. Journal of Controlled Release 2013, 172 (2), 444−455.
67. Ding, J.; Xiao, C.; Li, Y.; Cheng, Y.; Wang, N.; He, C.; Zhuang, X.*; Zhu, X.*; Chen, X.*, Efficacious hepatoma-targeted nanomedicine self-assembled from galactopeptide and doxorubicin driven by two-stage physical interactions. Journal of Controlled Release 2013, 169 (3), 193−203.
68. Ding, J.*; Shi, F.; Xiao, C.; Zhuang, X.; He, C.; Chen, X.*, Facile preparation of pH and reduction responsive PEGylated polypeptide nanogel for efficient doxorubicin loading and intracellular delivery. Journal of Controlled Release 2013, 172 (1), E40−E41.
69. Ding, J.#; Shi, F.#; Li, D.; Chen, L.*; Zhuang, X.*; Chen, X., Enhanced endocytosis of acid-sensitive doxorubicin derivatives with intelligent nanogel for improved security and efficacy. Biomaterials Science 2013, 1 (6), 633−646.
70. Ding, J.; Li, D.; Zhuang, X.; Chen, X.*, Self-Assemblies of pH-Activatable PEGylated Multiarm Poly(lactic acid-co-glycolic acid)-Doxorubicin Prodrugs with Improved Long-Term Antitumor Efficacies. Macromolecular Bioscience 2013, 13 (10), 1300−1307.
71. Ding, J.; Chen, J.; Li, D.; Xiao, C.; Zhang, J.; He, C.; Zhuang, X.*; Chen, X.*, Biocompatible reduction-responsive polypeptide micelles as nanocarriers for enhanced chemotherapy efficacy in vitro. Journal of Materials Chemistry B 2013, 1 (1), 69−81.
72. Cheng, Y.; He, C.; Xiao, C.; Ding, J.; Ren, K.; Yu, S.; Zhuang, X.; Chen, X.*, Reduction-responsive cross-linked micelles based on PEGylated polypeptides prepared via click chemistry. Polymer Chemistry 2013, 4 (13), 3851−3858.
73. Cheng, Y.; He, C.; Xiao, C.; Ding, J.; Cui, H.; Zhuang, X.; Chen, X.*, Versatile Biofunctionalization of Polypeptide-Based Thermosensitive Hydrogels via Click Chemistry. Biomacromolecules 2013, 14 (2), 468−475.
74. Cheng, Y.; He, C.; Ding, J.; Xiao, C.; Zhuang, X.; Chen, X.*, Thermosensitive hydrogels based on polypeptides for localized and sustained delivery of anticancer drugs. Biomaterials 2013, 34 (38), 10338−10347.
75. Zhao, L.#; Ding, J.#; Xiao, C.; He, P.; Tang, Z.; Pang, X.; Zhuang, X.; Chen, X., Glucose-sensitive polypeptide micelles for self-regulated insulin release at physiological pH. Journal of Materials Chemistry 2012, 22, 12319−12328.
76. Zhang, J.C.; Ding, J.X.; Xiao, C.S.; He, C.L.; Zhuang, X.L.*; Yang, Y.N.*; Chen, X.S., Synthesis and characterization of tumor-acidity-sensitive poly(L-lysine)-doxorubicin conjugates. Chemical Journal of Chinese Universities-Chinese 2012, 33, 2809−2815.
77. Shi, F.#; Ding, J.#; Xiao, C.; Zhuang, X.*; He, C.; Chen, L.*; Chen, X., Intracellular microenvironment responsive PEGylated polypeptide nanogels with ionizable cores for efficient doxorubicin loading and triggered release. Journal of Materials Chemistry 2012, 22, 14168−14179.
78. Li, D.#; Ding, J.X.#; Tang, Z.H.*; Sun, H.; Zhuang, X.L.; Xu, J.Z.*; Chen, X.S., In vitro evaluation of anticancer nanomedicines based on doxorubicin and amphiphilic Yshaped copolymers. International Journal of Nanomedicine 2012, 7, 2687−2697.
79. Ding, J.; Xiao, C.; Zhuang, X.; He, C.; Chen, X.*, Direct formation of cationic polypeptide vesicle as potential carrier for drug and gene. Materials Letters 2012, 73, 17−20.
80. Ding, J.; He, C.; Xiao, C.; Chen, J.; Zhuang, X.; Chen, X.*, pH-responsive drug delivery systems based on clickable poly(L-glutamic acid)-grafted comb copolymers. Macromolecular Research 2012, 20, 292−301.
81. Cheng, Y.; He, C.; Xiao, C.; Ding, J.; Zhuang, X.; Huang, Y.; Chen, X.*, Decisive role of hydrophobic side groups of polypeptides in thermosensitive gelation. Biomacromolecules 2012, 13, 2053−2059.
82. Zhao, L.; Ding, J.; He, P.; Xiao, C.; Tang, Z.; Zhuang, X.; Chen, X.*, An efficient pH sensitive oral insulin delivery system enhanced by deoxycholic acid. Journal of Controlled Release 2011, 152, E184−E186.
83. Yan, L.; Ding, J.; Qi, R.; Yang, L.; Hu, X.; Huang, Y.; Jing, X.*, Versatile synthesis of functional biodegradable polymers by ring-opening polymerization and microwave-assisted click reaction. Journal of Controlled Release 2011, 152, E249−E250
84. Wang, W.#; Ding, J.#; Xiao, C.; Tang, Z.; Li, D.; Chen, J.; Zhuang, X.*; Chen, X., Synthesis of amphiphilic alternating polyesters with oligo(ethylene glycol) side chains and potential use for sustained release drug delivery. Biomacromolecules 2011, 12, 2466−2474.
85. Ding, J.; Zhuang, X.; Xiao, C.; Cheng, Y.; Zhao, L.; He, C.; Tang, Z.; Chen, X.*, Preparation of photo-cross-linked pH-responsive polypeptide nanogels as potential carriers for controlled drug delivery. Journal of Materials Chemistry 2011, 21, 11383−11391.
86. Ding, J.; Xiao, C.; Zhao, L.; Cheng, Y.; Ma, L.; Tang, Z.; Zhuang, X.; Chen, X.*, Poly(L-glutamic acid) grafted with oligo(2-(2-(2-methoxyethoxy)ethoxy) ethyl methacrylate): Thermal phase transition, secondary structure, and self-assembly. Journal of Polymer Science Part A-Polymer Chemistry 2011, 49, 2665−2676.
87. Ding, J.; Xiao, C.; Yan, L.; Tang, Z.; Zhuang, X.; Chen, X.*; Jing, X., pH and dual redox responsive nanogel based on poly(L-glutamic acid) as potential intracellular drug carrier. Journal of Controlled Release 2011, 152, E11−E13.
88. Ding, J.; Xiao, C.; Tang, Z.; Zhuang, X.; Chen, X.*, Highly efficient "grafting from" an alpha-helical polypeptide backbone by atom transfer radical polymerization. Macromolecular Bioscience 2011, 11, 192−198.
89. Ding, J.; Xiao, C.; He, C.; Li, M.; Li, D.; Zhuang, X.; Chen, X.*, Facile preparation of a cationic poly(amino acid) vesicle for potential drug and gene co-delivery. Nanotechnology 2011, 22, 494012.
90. Ding, J.; Shi, F.; Xiao, C.; Lin, L.; Chen, L.*; He, C.; Zhuang, X.*; Chen, X., One-step preparation of reduction-responsive poly(ethylene glycol)-poly(amino acid)s nanogels as efficient intracellular drug delivery platforms. Polymer Chemistry 2011, 2, 2857−2864.
91. Cheng, Y.; He, C.; Xiao, C.; Ding, J.; Zhuang, X.; Chen, X.*, Versatile synthesis of temperature-sensitive polypeptides by click grafting of oligo(ethylene glycol). Polymer Chemistry 2011, 2, 2627−2634.
92. Cheng, J.; Ding, J.X.; Wang, Y.C.; Wang, J.*, Synthesis and characterization of star-shaped block copolymer of poly(ε-caprolactone) and poly(ethyl ethylene phosphate) as drug carrier. Polymer 2008, 49, 4784−4790.