Education

Ph.D, Graduate Institute of Microbiology, National Taiwan University College of Medicine, Taipei, Taiwan.

Biography

Research Interest

Professional Activities:

Specialities

• Toxocariasis
• Toxoplasmosis
• Dirofilariasis
• Parasite Immunology & Molecular Biology
• Molecular pathogenesis of parasitic diseases

Invited Speaker In International Conference Or University

1. Fan CK. Human Toxocarosis: Genetics and Environmental Factors. Sun Yat-Sen University, Guangdong, China, 2014.
2. Fan CK. Human immunodeficiency virus related opportunistic parasitic infections in Taiwan. Cho University, Tokyo, Japan, 2014.
3. Fan CK. Clinical Profile of Parasitic Diseases and Challenges in Taiwan: Retrospective Study from 2001~2012. Department of Infectious Diseases, Juntendo University Hospital, Tokyo, Japan, 2014.
4. Fan CK. Status of Toxocara canis infection among schoolchildren in Swaziland and São Tomé and Príncipe of Africa. Nanjing Medical University, Nanjing, China, 2013.
5. Fan CK. Factors affecting disease manifestation of Toxocarosis in humans: genetics and environment. Toxocara2012 Conference, Budapest, Hungary, 2012.
6. Fan CK. Neglected Tropical Parasitic Diseases Research in Africa: Taipei Medical University Experience. Juntendo University, Tokyo, Japan, 2012.
7. Fan CK. Toxocariasis: from bench to the trenches. Sun Yat-Sen University, Guangdong, China, 2012.
8. Fan CK. Toxocariasis: from bench to the trenches. Juntendo University, Tokyo, Japan, 2011.

Editorial Board Member Or Reviewers Of International Journals

Part One: Editorial Board Member Of International Journal

1. Pathogens and Global Health (SCI-indexed, Liverpool, UK, 2011~) (formerly Annals of Tropical Medicine & Parasitology)
2. Journal of Helminthology (SCI-indexed, Cambridge, UK, 2015~2017)
3. Asian Pacific Journal of Tropical Biomedicine (SCI-indexed, Beijing, China, 2010~)
4. Journal of Microbiology, Immunology & Infection (SCI-indexed, Taipei, Taiwan, 2011~)
5. The Open Tropical Medicine Journal (London, UK, 2008~)
6. Journal of Chinese Clinical Medicine (Beijing, China, 2009~)
7. ISRN Infectious Diseases (India, 2012~)
8. Journal of Biomedical Sciences (India, 2012~)
9. Tropical Medicine & Surgery (USA, 2013~)

Part Two: Reviewers Of International Scientific Journals

1. Acta Tropica, 2005, 2008, 2010
2. African Journal of Microbiology Research, 2012,2013
3. American Journal of Tropical Medicine & Hygiene, 2009
4. Annals of Tropical medicine & Parasitology, 2010-2011
5. Asian Pacific Journal of Tropical Disease, 2013, 2014
6. BMC Infectious diseases, 2005-2011
7. BMC Public Health, 2005-2008
8. Chinese Journal of Physiology, 2005
9. Eastern Journal of Medicine, 2009
10. European Journal of Gastroenterology & Hepatology, 2007, 2012, 2013
11. Indian Journal of Medical Microbiology, 2005
12. International Journal of Experimental Pathology, 2005, 2007
13. International Journal of Medical Sciences, 2010
14. International Journal of Tropical Disease & Health, 2012
15. ISRN Infectious Diseases, 2012-2013
16. Journal of Experimental Biology, 2012
17. Journal of Experimental & Clinical Medicine, 2010
18. Journal of Helminthology, 2012, 2015
19. Journal of Infection, 2012
20. Journal of Infectious Diseases and Immunity, 2012
21. Journal of Microbiology, Immunology & Infection, 2006-20 14
22. Journal of Parasitology and Vector Biology, 2010
23. Journal of Pediatric Infectious Disease (Turkey), 2006, 2008
24. Journal of Primatology (USA), 2013
25. Kaohsiung Journal of Medical Sciences, 2009~2012
26. Medical Science Monitor, 2005-2006, 2009
27. Pathogens and Global Health, 2012
28. PLoS ONE, 2014
29. Reports and Research in Tropical Medicine, 2012
30. Parasites & Vectors, 2012, 2013
31. Parasitology International, 2012, 2013
32. Reviews in Infection, 2010
33. Vaccine, 2014
34. PLoS NTDs
35. Saudi Medical Journal, 2014

Nomination into WHO'S WHO in 2009-2014

Publications

Chapters In Books

1. National Science of Council, Taiwan (NSC 99~2628 ~B ~038~001 ~MY3, $134,700 USD; 2010-2013)
2. National Science of Council, Taiwan (NSC 96~2628 ~B ~038~004~MY3, $170,000 USD; 2007-2010)

(2003~2014) *corresponding author

1. Shieh YH, Huang HM, Wang CC, Lee CC, Fan CK, Lee YL. Zerumbone enhances the Th1 response and ameliorates ovalbumin-induced Th2 responses and airway inflammation in mice. Int Immunopharmacol 24(2):383-391, 2015. (SCI)
2. Ching-Sheng Hung, Hung-Wen Su, Yu-Luen Lee, Hui-Wen Weng, Yin-Chin Wang, Toshio Naito, Akiko Tsubouchi, Giueng-Chueng Wang, Chia-Kwung Fan*.Seroprevalence, seroconversion, and toxoplasmosis risk factors among pregnant women in Taipei City, Taiwan. Jpn J Infect Dis (in press) 2015. (SCI)
3. Chen SH, Fan CK,Miser JS, Liu YL, Huang YJ, Wang CY. An infant boy with widespread ecchymoses and severe eosinophilia. J Microbiol Immunol Infect. 2014 Oct 7.
4. .___ BVol.24 pp.107-133 2014
5. Cheng PC, Huang CC, Chiang PF, Lin CN, Li LL, Lee TW, Lin B, Chen IC, Chang KW, Fan CK, Luo TY. Radioprotective effects of Antrodia cinnamomea are enhanced on immune cells and inhibited on cancer cells. International Journal of Radiation Biology 90(10):841-52, 2014. (SCI)
6. Fu CJ, Chuang TW, Lin HS, Wu CH, Liu YC, Langinlur MK, Lu MY, Hsiao WW, Fan CK*. Toxoplasma gondii infection: seroprevalence and associated risk factors among primary school children in the capital area of the Republic of the Marshall Islands. Jpn J Infect Dis 67:405-10, 2014. (SCI)
7. Fu CJ, Chuang TW, Lin HS, Wu CH, Liu YC, Langinlur MK, Lu MY, Hsiao WW, Fan CK*. Seroepidemiology of Toxocara canis infection among primary schoolchildren in the capital area of the Republic of the Marshall Islands. BMC Infect Dis14:261, 2014. (SCI)
8. Takahashi H, Tsubouchi A, Murai K, Yamanouchi M, Tanei M, Sakamoto R, Uehara Y, Fan CK, Naito T*. Seroprevalence of Toxoplasma gondii Infection among HIV Infected Patients in Tokyo, Japan. Clin Res HIV/AIDS 1(2): 1007, 2014.
9. Akinwale OP*, Hock TT, Fan CK, Zheng Q, Haimo S, Ezeh C, Gyang PV. Differentiating Schistosoma haematobium from Schistosoma magrebowiei and other closely related schistosomes by polymerase chain reaction amplification of a species specific mitochondrial gene. Trop Parasitol. 4(1):38-42, 2014.
10. Fan CK*, Lin HC, Liao CW, Huang YC, Chou CM, et al. Angiostrongylus Cantonensis Infection: Potential Threats to Inhabitants through Consumption of Giant African Land Snail in Democratic Republic of Sao Tome E Principe, West Africa. Trop Med Surg 1: e108, 2013. doi: 10.4172/2329-9088.1000e108
11. Fan CK*, Chang YT, Hsu CH, Liao CW, Huang YC, et al. Lymphatic Elephantiasis in One Neglected African Country-Democratic Republic of Sao Tome e Principe. Trop Med Surg 1: 108, 2013. doi:10.4172/tpms.1000108
12. Hsiao WW, Liao HS, Lin HH, Lee YL, Fan CK*, Liao CW, Lin PY, Hwu ET, Chang CS*. Biophysical analysis of astrocytes apoptosis triggered by larval E/S antigen from cerebral toxocarosis-causing pathogen Toxocara canis. Analytic Science 29(9):885-92, 2013. (SCI)
13. Huang HM, Hsiao G, Fan CK,Lin CL, Leu SJ, Chiang BL, Lee YL*. Notch ligand delta-like 4-pretreated dendritic cells alleviate allergic airway responses by enhancing IL-10 production. PLoS One 8(5):e63613, 2013. (SCI)
14. Cheng PC, Lin CN, Peng SY, Li LL, Luo TY, Fan CK,Lee KM. A study of immunomodulatory genes responses to macrophages of Schistosoma japonicum infection during different stages by microarray analysis. Acta Trop 127: 251-260, 2013. (SCI)
15. Fan CK*, Liao CW, Cheng YC. Factors affecting disease manifestation of toxocarosis in humans: genetics and environment. Vet Parasitol 193:342-52, 2013. (SCI)
16. Liu CT, Chen YC, Chen TH, Barghouth U, Fan CK*.Intestinal paragonimiasis with colonic ulcer and hematochezia in an elderly Taiwanese woman. Korean J Parasitol 50:349-52, 2012. (SCI)
17. Cheng PC, Chiang PF, Lee KM, Yeh CH, Hsu KL, Liu SW, Shen LH, Peng CL, Fan CK, Luo TY. Evaluating the potential of a new isotope-labelled glyco-ligand for estimating the remnant liver function of schistosoma-infected mice. Parasite Immunol 35(3-4):129-39, 2013. (SCI)
18. Chu TB, Liao CW, Nara T, Huang YC, Chou CM, Liu YH, Fan CK*.Enterobius vermicularis infection is well controlled among preschool children in nurseries of Taipei City, Taiwan. Rev Soc Bras Med Trop 45:646-8, 2012. (SCI)
19. Chiang TY, Hsieh HH, Kuo MC, Chiu KT, Lin WC, Fan CK,Fang CT, Ji DD. Seroepidemiology of Toxoplasma gondii Infection among healthy blood donors in Taiwan. PLoS One 7:e48139, 2012. (SCI)
20. Chu T, Liao C, Huang Y, Chang Y, Costa A, Ji D, Nara T, Tsubouchi A, Chang PW, Chiu W, Fan C*. Prevalence of Schistosoma intercalatum and S. haematobium Infection among Primary Schoolchildren in Capital Areas of Democratic Republic Of São Tomé and Príncipe, West Africa. Iran J Parasitol 7: 67-72, 2012. (SCI)
21. Fan CK*, Lee LW, Liao CW, Huang YC, Lee YL, Chang YT, da Costa Âdos S, Gil V, Chi LH, Nara T, Tsubouchi A, Akinwale OP. Toxoplasma gondii infection: relationship between seroprevalence and risk factors among primary schoolchildren in the capital areas of Democratic Republic of São Tomé and Príncipe, West Africa. Parasit Vectors 5:141, 2012. (SCI)
22. Fan CK*, Liao CW, Lyu SY, Sukati H, Ji DD, Cho CM, Jien JY, Huang YC, Chang Peter WS, Chiu WT, Nara T, Tsubouchi A, Huang YH, Tu CC, Lan SJ, Chao Jane CJ. Prevalence of intestinal parasitic infections among primary schoolchildren in areas devoid of sanitation in northwestern Kingdom of Swaziland, Southern Africa. Pathogens and Global Health 106: 60-63, 2012. (SCI)
23. Nara T, Hashimoto M, Hirawake H, Liao CW, Fukai Y, Suzuki S, Tsubouchi A, Morales J, Takamiya S, Fujimura T, Taka H, Mineki R, Fan CK, Inaoka DK, Inoue M, Tanaka A, Harada S, Kita K, Aoki T. Molecular interaction of the first 3 enzymes of the de novo pyrimidine biosynthetic pathway of Trypanosoma cruzi. Biochem Biophys Res Commun. 418(1):140-3, 2012. (SCI)
24. Liao CW, Sukati H, Nara T, Tsubouchi A, Chou CM, Jian JY, Huang YC, Chang PW, Chiu WT, Huang YH, Fan CK*. Prevalence of Schistosoma haematobium infection among schoolchildren in remote areas devoid of sanitation in northwestern Swaziland, Southern Africa. Jpn J Infect Dis. 64(4):322-6, 2011. (SCI)
25. Chu TB, Liao CW, D’Lamini P, Chang Peter WS, Chiu WT, Du WY, Fan CK*. (2010). Prevalence of Schistosoma haematobium infection among inhabitants of Lowveld, Swaziland, an endemic area for the disease. Tropical Biomedicine 27(2): 337–342 (SCI)
26. Shih YC, Chen CM, Huang YH, Liao CW, Fan CK, Yang CH. (2010). Subcutaneous cysticercosis diagnosed by mitochondrial DNA analysis. Int J Dermatol. 49(6): 672-5. (SCI)
27. Liang SY, Hsia KT, Chan YH, Fan CK, Jiang DD, Landt O, Ji DD. (2010). Evaluation of a new single-tube multiprobe real-time PCR for diagnosis of Entamoeba histolytica and Entamoeba dispar. J Parasitol. 96(4):793-7. (SCI)
28. Liao CW, Sukati H, D’Lamini P, Chou CM, Liu YH, Huang YC, Chung MH, Mtsetfwa JS, Jonato J, Chiu WT, Chang PWS, Du WY, Chan HC, Chu TB, Cheng HC, Su WW, Tu CC, Cheng CY, Fan CK*. (2010). Seroprevalence of Toxocara canis infection among children in the Kingdom of Swaziland, southern Africa. Annals of Tropical Medicine and Parasitology 104(1):73-80. (SCI)
29. Li MH, Liao CW, Lee YL, Ooi HK, Du WY, Lu SC, Huan HI, Su KE, Fan CK*. (2010). Infectivity and development of Metagonimus yokagawai in experimentally infected domestic ducks (Cairina moschata). Veterinary Parasitology 168(1-2): 45-50. (SCI)
30. Liao CW, Lee YL, Sukati H, Lamini PD’, Huang YC, Chiu CJ, Liu YH, Chou CM, Chou WT, Du WY, Hung CC, Chan HC, Chu B, Cheng HC, Su J, Tu CC, Cheng CY, Fan CK*. (2009). Seroprevalence of Toxoplasma gondii infection among children in Swaziland, southern Africa. Annals of Tropical Medicine and Parasitology 103: 731–736. (SCI)
31. Chuang CC, Su KE, Chen CW, Fan CK, Lin FK, Chen YS, Du WY*. (2009). Anti-CCR3 monoclonal antibody inhibits eosinophil infiltration in Angiostrongylus cantonensis­infected ICR mice. Acta Tropica 113(3):209-13. (SCI)
32. Chang TK, Liao CW, Huang YC, Chang CC, Chou CM, Tsay HC, Huang A, Guu SF, Kao TC, Fan CK*.(2009). Prevalence of Enterobius vermicularis Infection among preschool children in kindergartens of Taipei City, Taiwan in 2008. Korean J Parasitol. 47(2): 185-7. (SCI)
33. Liao CW, Cho WL*, Kao TC, Su KE, Lin YH, Fan CK*. (2008). Blood-brain barrier impairment with enhanced SP, NK-1R, GFAP and claudin-5 expressions in experimental cerebral toxocariasis. Parasite Immunology, 30: 525-534. (NSC 94-2320-B-038 - 025;NSC 95-2320-B-038-007) (SCI)
34. Liao CW, Fan CK*, Kao TC, Ji DD, Su KE, Lin YH, Cho WL*. (2008). Brain injury-associated biomarkers of TGF-beta1, S100B, GFAP, NF-L, tTG, AbetaPP, and tau were concomitantly enhanced and the UPS was impaired during acute brain injury caused by Toxocara canis in mice. BMC Infectious Diseases, 8: 84. (NSC 94-2320-B-038 -025; NSC 95-2320-B-038-007) (SCI)
35. Wu MS, Liao CW, Du WY, Kao TC, Su KE, Lin YH, Chang CC, Fan CK*. (2008). Enhanced expression of transforming growth factor-beta 1 in inflammatory cells, alpha-smooth muscle actin in stellate cells, and collagen accumulation in experimental granulomatous hepatitis caused by Toxocara canis in mice. Acta Tropica, 105: 260-268. (SCI, NSC 93-2314-B-038-065) (SCI)
36. Lin SM, Liao CW, Lin YH, Lee CC, Kao TC, Fan CK* .(2008). Inducible nitric oxide synthase inhibition influenced granuloma formation with suppressed collagen expression in myositis caused by Toxocara canis in mice. Parasitology Research, 102: 577-585. (SCI)
37. Tsai YT, Cheng PC, Fan CK, Pan TM*. (2008).Time-dependent persistence of enhanced immune response by a potential probiotic strain Lactobacillus paracasei subsp. paracasei NTU 101. Int J Food Microbiol.(128):219-225. (SCI)
38. Wang IC, Fan PC, Lu SC, Fan CK,Su KE. (2008). Suppression of host Th1-type granulomatous inflammation by Taenia solium metacestodes is related to down-regulation of osteopontin gene expression. Int J Parasitol.(38) :239-248. (SCI)
39. Fan CK,* Hung CC, Su KE, Chiou HY, Gil V, Ferreira MCR, Tseng LF. (2007). Seroprevalence of Toxoplasma gondii infection among inhabitants in the Democratic Republic of Sao Tome and Principe. Transactions of the Royal Society of Tropical Medicine and Hygiene.(101) :1157-1158. (SCI)
40. Hung CC, Fan CK*, Su KE, Sung FC, Chiou HY, Gilf V, dos Reis Ferreir MC, de Carval JM, Cruz C. (2007). Serological screening and toxoplasmosis exposure factors among pregnant women in the Democratic Republic of Sao Tome and Principe. Transactions of the Royal Society of Tropical Medicine and Hygiene.(101):134-139. (SCI)
41. Chuang CC, Chen CW, Fan CK,Su KE, Tsai YT, Du WY. (2007). Angiostrongylus cantonensis: Apoptosis of in inflammatory cells induced by treatment with mebendazole or/and interleukin 12 in mice. Experimental Parasitology.(115):226-232. (SCI)
42. Lou HY, Tsai PC, Chang CC, Lin YH, Liao CW, Kao TC, Su KE, Lin YH, Chang CC, Fan CK* (2007) A case of human diphyllobothriasis in northern Taiwan after eating raw fish fillets. Journal of Microbiology, Immunology and Infection, 40: 452-456. (SCI Expanded)
43. Chia-Kwung Fan*, Chien-Ching Hung, Kua-Eyre Su, Fung-Chang Sung, Hung-Yi Chiou, Vilfrido Gil, Maria da Conceicao dos Reis Ferreira. (2006). Seroprevalence of Toxoplasma gondii infection among pre-schoolchildren aged 1 to 5 years in the Democratic Republic of Sao Tome and Principe, Western Africa. Transactions of the Royal Society of Tropical Medicine and Hygiene.(100) :446-449. (SCI)
44. Fan CK*, Liao CW, Kao TC, Li MH, Du WY, Su KE. (2005). Sero-epidemiology of Toxocara canis infection among aboriginal schoolchildren in the mountainous areas of north-eastern Taiwan. Annals of Tropical Medicine and Parasitology, 99: 593-600. (SCI)
45. Fan CK*, Lan HS, Hung CC, Chung WC, Liao CW, DU WY, Su KE(2004). Seroepidemiology of Toxocara canis infection among mountain aboriginal adults in Taiwan. American Journal of Tropical Medicine and Hygiene.(71):216-221. (SCI)
46. Fan CK*, Liao CW, Wu MS, Hu NY, Su KE(2004).Prevalence of Pediculus cap itis infestation among school children of Chinese refugees residing in mountainous areas of northern Thailand. Kaohsiung Journal of Medical Sciences. (20): 183-187.
47. Fan CK*, Lin YH, Hung CC, Su KE(2004). Larval migratory behavior of long-term‑ maintained Toxocara canis embryonated eggs in mice. Taiwan Veterinary Journal.(30) :99-105.
48. Fan CK*, Lin YH, Hung CC, Su KE(2004).Experimental ocular toxocariasis in mice infected with long-term-maintained embryonated eggs of Toxocara canis. Kaohsiung Journal of Medical Sciences.(20):317-322. (SCI)
49. Fan CK*, Su KE (2004).Cross-reactions of sera from Ascaris suum, Toxocara canis, and Angiostrongylus cantonensis infected mice with Ascaris suum antigens. Parasitology International.53:263-271. (SCI)
50. Fan Chia-Kwung*, Su Kua-Eyre, Tsai Yu-Zen (2004).Serological survey of Toxoplasma gondii infection among slaughtered pigs in northwestern Taiwan. Journal of Parasitology.(90):653-654. (SCI)
51. Fan CK*, Hung CC, Du WY, Liao CW, Su KE(2 004). Seroepidemiology of Toxocara canis infection among mountain aboriginal schoolchildren living in contaminated districts in eastern Taiwan. Tropical Medicine and International Health.(9):1312-1318. (SCI)
52. Fan CK, Lin YH, Hung CC, Chang SF, Su KE*(2004).Enhanced inducible nitric oxide synthase expression and nitrotyrosine accumulation in experimental granulomatous hepatitis caused by Toxocara canis in mice. Parasite Immunology.(26):273-281. (SCI)
53. Fan CK*, Hung CC, Lin HY, Li MH, Su KE(2004).Enhanced expressions of transforming growth factor-β1 in inflammatory cells and secretory granules in Paneth cells in the small intestine of mice infected with Toxocara canis. Parasitology Research.(94):397-404. (SCI)
54. Fan CK*, Liao CW, Wu MS, Su KE, Han BC. (2003).Seroepidemiology of Toxoplasma gondii infection among Chinese aboriginal and Han people resident in mountainous areas of northern Thailand. Journal of Parasitology.(89):1239-1242. (SCI)
55. Fan CK*, Lin YH, Du WY, Su KE (2003).Infectivity and pathogenicity of 14-month­cultured embryonated eggs of Toxocara canis in mice. Veterinary Parasitology.(113):145-155. (SCI)
56. Du WY, Liao JW, Fan CK, Su KE* (2003). Combined treatment with interleukin-12 and mebendazole lessened experimental eosinophilic meningitis caused by Angiostrongylus cantonensis in ICR mice. Infection and Immunity.(71):3947-3953. (SCI)