Education

Biography

Research Interest

1. Cellular, molecular and genetic mechanisms regulating preimplantation embryogenesis.
2. Factors affecting early embryo arrest, mortality and survival in embryos produced by reproductive biotechnologies.
3. Epigenetic and signal transduction pathways in controlling early embryo development.
4. Metabolomic and proteomic assessment of embryonic health.

Scientific Activities

Publications

1. Selokar N, Liz St. John, Tamas Revay, W Allan King, Singla S and Pavneesh Madan. Effect of histone deacetylase inhibitor valproic acid (VPA) treatment on donor cell growth characteristics, cell cycle arrest, apoptosis and handmade cloned bovine embryo production efficiency. Cell Reprogram 2013 Nov 1. [Epub ahead of print].
2. Nathan T Bain, Pavneesh Madan, Dean H Betts. Elevated p66Shc is associated with intracellular redox imbalance in developmentally compromised bovine embryos. Mol Reprod Dev 2013 Jan; 80(1): 22-34.
3. Lindsay H. Bergeron, Stephanie G. Nykamp, Brigitte A. Brisson, Pavneesh Madan and Cathy J. Gartley. An evaluation of the efficacy of color Doppler ultrasonography of canine ovaries for detecting the preovulatory LH peak. Theriogenology 2013 Jan 15 79(2):274-83.
4. Mao Li, Matthilakath M. Vijayan, W. Allan King, John F. Leatherland and Pavneesh Madan (2012). Glucocorticoid receptor activation following elevated oocyte cortisol content is associated with zygote activation, early embryo cell division, and IGF system gene responses in rainbow trout. J Endocrinol2012 Oct 215(1):137-49.
5. Selokar N, Saini M, Muzaffer M, Krishnakanth G, Saha A, Chauhan M, Manik R, Palta P, Madan Pavneesh and Singla S. Roscovitine treatment improves synchronization of donor cell cycle in G0/G1 stage and invitro development of handmade cloned buffalo (Bubalus bubalis) embryos. Cell Reprogram2012 Apr 14(2):146-54.
6. Lindsay H. Bergenon, Stephanie G. Nykamp, Brigitte A. Brisson, Pavneesh Madan and Cathy J. Gartley. An evaluation of the efficacy of color Doppler ultrasonography of canine ovaries for detecting the preovulatory LH peak. Theriogenology (Revision MSID: THERIO-D-11-00793R1).
7. Pavneesh Madan. Arrest or survive: a decision of the early preimplantation embryo that influences fertility. In: Moo-Young M, (ed.) Comprehensive Biotechnology, Second Edition 2011, vol. 4, pp. 469-476.
8. Nathan T Bain, Pavneesh Madan, Dean H Betts. The early embryo response to intracellular reactive oxygen species is developmentally regulated. Reprod Fertil Dev 2011 May; 23(4): 561-75.
9. Blondin P, Beaulieu M, Fournier V, Morin N, Crawford L, Pavneesh Madan, King WA. Analysis of bovine sexed sperm for IVF from sorting to the embryo. Theriogenology 2009 Jan 1; 71 (1):30-8.
10. Dean H. Betts and Pavneesh Madan. Permanent Embryo Arrest: Current Concept and Molecular Mechanism. Molecular Human Reproduction 2008 Aug 14 (8): 445-53.