Chaur-Dong Hsu, MD, MPH, FACOG
Hassan Nooman Sallam, MB, ChB, DGO, Dr Ch O&G, FRCOG, PhD.
Professor in Obstetrics and Gynaecology
  • Department of Obstetrics and Gynaecology
    University of Alexandria
    Alexandria, Egypt
    Phone: - +20 3 4245750
    E-mail: - hnsallam@link.net

Education

Academic qualifications
1972 MB, ChB (Alex), (Excellent grades, top of class)
1975 D.G.O. (Alex)
1981 Dr Ch O&G (Alex)
1982                                MRCOG
1983 PhD (London), (Reproductive biochemistry)
1995                                 Elevated to FRCOG
 

Biography

Hassan Nooman Sallam is professor and former head of the department of obstetrics and gynaecology in Alexandria University in Egypt and clinical director of the Alexandria Fertility and Assisted Reproduction Center established in 1984. He was a founding member of the IVF unit at King’s College Hospital (London, UK) in 1981 and St-Luke’s Roosevelt Hospital Center – Columbia University (New York, NY, USA) in 1984. Dr. Sallam qualified form Alexandria University where he also completed his residency in obstetrics and gynaecology. He subsequently worked in the UK under the chairmanship of Professor Sir Malcolm McNaughton in Glasgow Royal Maternity Hospital in 1978 and Professor Stuart Campbell at King’s College Hospital in London from 1979 to 1984. Besides the fellowship of the Royal College of Obstetricians and Gynaecologists (FRCOG), he holds a doctorate degree in Obstetrics and Gynaecology from Alexandria University and a PhD in reproductive biochemistry from the University of London. He has published more than 100 papers in national and international refereed journals in 3 languages as well as 3 books. He is the co-author of “Infertility and Assisted Reproduction”, the reference textbook published in 2008 by Cambridge University Press. Dr. Sallam is former vice-dean and director of research in Alexandria University Faculty of Medicine. He was the founder and former director of the Alexandria (formerly Suzanne Mubarak) Regional Center for Women's Health and Development. In 1998, he served as the overseas examiner to the Royal College of Obstetricians and Gynaecologists in London. He was also the recipient of the 2012 Historical Lecture of the Royal College of Obstetricians and Gynaecologists of England. Dr. Sallam served/serves on the editorial boards of many journals including "Human Reproduction" from 2000 to 2004, "Reproductive Biomedicine Online" from 2002 to 2008, the "Middle East Fertility Society Journal" and “Facts, Views and Visions in OB/GYN” (Official Journal of the Flemish Society of Obstetrics and Gynecology) since their inception and is an ad hoc reviewer for 12 other journals. He is a founding board member of the Middle East Fertility Society, based in Beirut, Lebanon and the founding chairman of the Mediterranean Society for Reproductive Medicine, based in Florence, Italy.  He is also an executive board member of the International Society of IVF. His current research interests include biochemical approaches for embryo selection, optimizing embryo transfer, prediction of OHSS, endometriosis-associated infertility and repeated implantation failure. He is also active in the fields of “infertility for developing countries” and “combating violence against women”.

Research Interest

  • Evidence-based medicine, particularly in the area of infertility management and assisted reproduction
  • Embryo transfer in assisted reproduction
  • Embryo selection in assisted reproduction using biochemical and computer-assisted approaches
  • Endometriosis-associated infertility
  • Repeated implantation failure
  • Non-isotopic immunoassay, in particular chemiluminescence immunoassay and fluoro-immunoassay of pituitary and ovarian hormones.
  • Determination of the fertile period for the purpose of natural family planning using biophysical, biological and biochemical parameters.
  • The postpartum hypothalamic-hypophyseal-ovarian axis.
  • Prenatal diagnosis of congenital diseases.
  • Embryo implantation and preeclamptic toxaemia
  • Ethics of human reproduction
  • Preventing and combating violence against women
  • Infertility in developing countries
 

Scientific Activities:

Appointments
1972 – 1973 House officer (Alexandria University Hospitals, September 1972 to August 1973).
1973 – 1976 Resident registrar in obstetrics and gynaecology at the Shatby Hospital for Women (Alexandria University). Chief of service: Professor H.K. Toppozada, MD, MCh. September 1973 to April 1976).
1976 – 1978 Assistant lecturer, department of Obstetrics and Gynaecology, Alexandria University at the Shatby Hospital for Women. Head of Department: Professor Mourad El-Abd, MD, MCH, FRCOG(Hon). (April 1976 to July 1978).
1978 – 1979 Senior House Officer in Obstetrics and Gynaecology at the Glasgow Royal Maternity Hospital (Professor Sir Malcolm McNaughton, MD, PRCOG, FRCPG) and the Royal Samaritan Hospital for Women (Dr. Matthew Garrey, FRCOG, FRCS), (August 1978 - July 1979).
1979 – 1983 Research Fellow and Honorary registrar in endocrinological gynaecology and infertility, King's College Hospital, London (Professor Stuart Campbell, FRCOG), (August 1979 to February 1984).
1983 – 1984 Clinical Fellow, in-vitro fertilization programme, Woman's Hospital, St-Luke's-Roosevelt Hospital Center, Columbia University, New York, NY, U.S.A. (Professor Robert Newirth, MD), (March 1984 to June 1984).
1984 – 1984 Senior Lecturer in Obstetrics and Gynaecology, the University of Alexandria in Egypt (July 1984 - March 1987).
1987 – 1992 Associate professor in Obstetrics and Gynaecology, the University of Alexandria in Egypt (April 1987 - May 1992).
1992 – now Professor in Obstetrics and Gynaecology, the University of Alexandria in Egypt (June 1992 till now)
2005 – 2008 Vice-dean and director of research, Faculty of Medicine, the University of Alexandria in Egypt (November 2005 till September 2008)
2006 – 2011 Founding Director, Alexandria Regional Center for Women’s Health and Development, Alexandria, Egypt (formerly Suzanne Mubarak Regional Center for Women’s Health and Development)
2008 – 2010 Chairman, Department of Obstetrics and Gynaecology, the University of Alexandria in Egypt
 
Teaching, lecturing and examining experience:
  • Examiner to the Royal College of Obstetricians and Gynaecologists of England (MRCOG, part II), 1998
  • Clinical demonstrations, tutorial and lectures to undergraduate and postgraduate medical students, student nurses and midwives at King's College Hospital, Columbia University and Alexandria University Medical Schools.
  • Regular speaker at the international course on "Advanced course in Obstetrical and Gynaecological ultrasound" held three times a year at King's College Hospital from December 1981 until March 1984. Course director: Professor Stuart Campbell.
  • Regular examiner at the bachelor, master and doctorate degrees of Alexandria University and external postgraduate examiner at Ain Shams and Al-Azhar Universities in Cairo and the High Institute of Public Health and the High Institute of Medical Research both of Alexandria University.
  • Examiner at the bachelor degree of Benghazi University, Libya, December 1992
  • Examiner at the bachelor degree of the Gulf University in Bahrain, June 2008.
  • Regular examiner at the Master Degree of the Senghor Francophonic University, Alexandria (2010-now) [in French]
  • Course director of the regular course on “Ultrasound in Obstetrics and Gynaecology” (1985-1986)
  • Course designer of the course “Infertility” in the “Egyptian Ministry of Health Unified Curricula” sponsored by the United Nations Population Fund
  • Course chair, joint ASRM/MEFS pre-congress postgraduate course on “Controversies in Assisted Reproduction”. 69th Annual Meeting of the American Society for Reproductive Medicine ASRM, San Diego, CA, 21 October 2012
  • Course chair, Pre-congress course on “Infertility and Assisted Reproduction in Developing Countries”, 1st FIGO Africa Regional Conference of Gynecology and Obstetrics, Addis Ababa, Ethiopia, 2-5 October 2013
  • Course organizer (5 days), chair and speaker at the Senghor Francophonic University, Alexandria on “Santé de reproduction” (12-17 January 2014) [in French]
  • Course organizer and speaker. 13th Annual meeting of the Nepal Society of Obstetrics and Gynaecology, Kathmandu, Nepal, 6th April 2014 on “Update in the management of infertility”
Membership of learned societies and expert groups:
  • Fellow of the Royal College of Obstetricians and Gynaecologists of England
  • Member of the Society of Gynecologic Investigation (SGI)
  • Member of the European Society of Human Reproduction and Embryology (ESHRE)
  • Member of the American Society of Reproductive Medicine ASRM (formerly American Fertility Society)
  • Member of the International Society for the Study of Hypertension in Pregnancy
  • Founding board member and past secretary of the Middle East Fertility Society (MEFS)
  • Member of the Egyptian Society of Obstetrics and Gynaecology
  • Member of the Egyptian Fertility Care Society
  • Member of the Egyptian Society for Genetic Counseling
  • Member of the Egyptian Representative Committee of the Royal College of Obstetricians and Gynaecologists of England (1987-2000)
  • Past member of the British Medical Association
  • Chairman of the Mediterranean Society for Reproductive Medicine (MSRM) 2002-2007
  • President of the Mediterranean Society for Reproductive Medicine (MSRM) 2008 – 2011
  • Chairman of the Minimal Invasive Surgery Society of Egypt (MISS-E) 2011 - now
  • Member of the executive board of the Alexandria Greco-Roman museum
  • Member of the WHO expert group meeting organized by EMRO on “the new vaccine against HPV”, Rabat, Morocco, 25-27 March 2008.
  • Member of the WHO expert group meeting organized by WHO Special Programme on Research Development and Research Training in Human Reproduction, on “Infertility in developing countries” Geneva, Switzerland, 2-4 December 2008.

Publications

  1. Sallam HN, Sallam NH. Religious aspects of assisted reproduction. Facts Views Vis Obgyn, 2016, 8 (1): 33-48
  2. Soliman AA, Shaalan W, Abdel-Dayem T, Awad EE, Elkassar Y, Lüdders D, Malik E, Sallam HN. Power Doppler flow mapping and four-dimensional ultrasound for evaluating tubal patency compared with laparoscopy. Eur J Obstet Gynecol Reprod Biol. 2015 Dec;195:83-7
  3. Abdel-Hadi M, Khalaf A, Aboulkassem H, Naeem N, Baqy MA, Sallam H. Cervical intraepithelial lesions in females attending Women's Health Clinics in Alexandria, Egypt. Cytojournal. 2015 Jun 23;12:13.
  4. Sallam HN. Ultrasound guidance during embryo transfer: a systematic review and meta-analysis of randomized controlled trials. Ultrasound Obstet Gynecol 2015; 45: 755–758
  5. Sallam H, Ezzeldin F and Sallam N. Role of in-vitro fertilization in unexplained female infertility. In: Unexplined Infertility. Eds: G. Schattman, S. Esteves and A. Agarwal. Springer, New York pp. 329-334, 2015
  6. Shaltout MF, Sallam HN, AbouSeeda M, Moiety F, Hemeda H, Ibrahim A, Sherbini ME, Rady H, Gopala K, DeAntonio R. Prevalence and type distribution of human papillomavirus among women older than 18 years in Egypt: a multicenter, observational study. Int J Infect Dis. 2014 Dec;29:226-31.
  7. Abou-Setta AM, Peters LR, D'Angelo A, Sallam HN, Hart RJ, Al-Inany HG. Post-embryo transfer interventions for assisted reproduction technology cycles. Cochrane Database Syst Rev. 2014 Aug 27;8:CD006567.
  8. Coughlan C, Ledger W, Wang Q, Liu F, Demirol A, Gurgan T, Cutting R, Ong K, Sallam H, Li TC. Recurrent implantation failure: definition and management. RBM Online 2014 Jan: 28(1): 18-34.
  9. Sallam HN, Abdel-Baki M, Sallam NH. Does ovulation induction increase the risk of gynecological cancer? Views and Vision in OB/GYN, 2013, 5 (4): 265-273.
  10. Elgindy EA, El-Haieg DO, Khorshid OM, Ismail EI, Abdelgawad M, Sallam HN, Abou-Setta AM. Gonadatrophin Suppression to Prevent Chemotherapy-Induced Ovarian Damage: A Randomized Controlled Trial. Obstet Gynecol. 2013 Jan;121(1):78-86.
  11. Cohlen B and Sallam H. Indications for IUI. In: “Intra-uterine insemination: an evidence based guideline for daily practice”. Eds: Ben Cohlen and Willem Ombelet. Informa Healthcare, London, UK.2013: 17-20.
  12.  Sallam H. Factors affecting the success of IUI – Implications for developing countries. In: “Intra-uterine insemination: an evidence based guideline for daily practice”. Eds: Ben Cohlen and Willem Ombelet. Informa Healthcare, London, UK. 2013: 167-170.
  13. Mamdouh HM. Ismail HM, Kharboush IF, Tawfik MM, El Sharkawy OG, Abdel-Baky M and Sallam HN.Prevalence and risk factors for spousal violence among women attending health care centres in Alexandria, Egypt. East Med Health J. 2012: Nov;18(11):1118-1126.
  14. Sallam HN, Galal AF and Moeity FS. Excess cervical mucus and retained embryo at embryo transfer. In: Assisted reproduction techniques: Management challenges, First Edition. Eds: Khaldoun Sharif and Arri Coomarasamy. Blackwell Publishing Ltd 2012: 257-260
  15. Sallam HN, Ezzeldin F, Agameya AF, Abdel-Rahman AF, El-Garem Y. The definition of 'poor response': Bologna criteria. Hum Reprod. 2012 Feb;27(2):626-7.
  16. Soliman AA, Elsabaa B, Hassan N, Sallam H, Ezzat T. Degenerated huge retroperitoneal leiomyoma presenting with sonographic features mimicking a large uterine leiomyoma in an infertile woman with a history of myomectomy: a case report. J Med Case Reports. 2011 Dec 16;5(1):578.
  17. Kharboush IF, Ismail HM, Kandil AA, Mamdouh HM, Muhammad YY, El Sharkawy OG and Sallam HN. Raising the Breast Health Awareness amongst Women in an Urban Slum Area in Alexandria, Egypt. Breast care, 2011, 6(5): 375-9
  18. Tayel SM, Ismael H, Kandil H, Abd Rabuh AR, Sallam H. Congenital adrenal hyperplasia in Alexandria, Egypt: A high prevalence justifying the need for a community-based newborn screening program. J Trop Pediatr: 2011 June;57(3): 232-4
  19. Sallam HN. The evidence-based practice of assisted reproduction. In: Human Assisted Reproductive Technology. Eds: David Gardner, Botros Rizk and Tommaso Falcone. Cambridge University Press, New York, 2011: 152-166
  20. Sallam HN. Keep it simple: specific aspects of IUI in developing countries. Views and Vision in OB/GYN, 2010, Monograph on Artificial Insemination: 91-96
  21. Ombelet W, Campo R, Frydman R, Huyser K, Nargund G, Sallam H, van Balen F and van Blerkom J. The Arusha project: Accessible infertility care in developing countries – a reasonable option? Views and Vision in OB/GYN, 2010, Monograph on infertility in developing countries: 107-115
  22. Sallam HN. Aspects cliniques du transfert embryonnaire [French]. In: Physiologie, pathologie et thérapie de la reproduction chez l’humain. Eds: Christophe Poncelet et Christophe Sifer. Springer-Verlag France, Paris, 2010: 523-536
  23. Sallam HN. Aristotle – Godfather of evidence-based medicine. Facts, Views and Vision in OB/GYN, 2010, 2 (1): 11-19
  24. Abou-Setta AM, D’Angelo A, Sallam HN, Hart RJ, Al-Inany HG. Post-embryo transfer interventions for in vitro fertilizationand intracytoplasmic sperm injection patients. Cochrane Database Syst Rev. 2009 Oct 7;(4):CD006567
  25. Sallam HN. Infertility in developing countries – Funding the project. Hum Reprod. July 2008 (Suppl 1): 97-101
  26. Sallam H. The impact of transabdominal ultrasound-guided embryo transfer. In: Embryo transfer. Editor: Gautam Allahbadia. Jaypee Brothers Medical Publishers (P) Ltd. 2008: 275-286
  27. Sallam H, Galal AF, Rashed A. Menopause in Egypt: past and present perspectives. Climacteric. 2006 Dec;9(6):421-9
  28. Nardo LG, Sallam HN. Progesterone supplementation to prevent recurrent miscarriage and to reduce implantation failure in assisted reproduction cycles. Reprod Biomed Online. 2006 Jul;13(1):47-57
  29. Sallam H, Garcia-Velasco J, Dias S, Arici A. Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis. Cochrane Database Syst Rev. 2006 Jan 25;(1):CD004635
  30. Sallam HN, Ezzeldin F, Agameya AF, Rahman AF, El-Garem Y. Defining poor responders in assisted reproduction. Int J Fertil Women’s Med. 2005 May-Jun;50(3):115-20
  31. Sallam HN, Farrag A, Agameya AF, El-Garem Y, Ezzeldin F. The use of the modified hypo-osmotic swelling test for the selection of immotile testicular spermatozoa in patients treated with ICSI: a randomized controlled study. Hum Reprod. 2005 Dec;20(12):3435-40
  32. Sallam HN. Embryo transfer: factors involved in optimizing the success. Curr Opin Obstet Gynecol. 2005 Jun;17(3):289-98
  33. Sallam HN. Should embryo transfer always be performed under ultrasound guidance? Ultrasound Obstet Gynecol. 2004 Sep;24(4):383-6
  34. Sallam HN. Assisted hatching. Minerva Ginecol. 2004 Jun;56(3):223-34
  35. Sallam HN. Embryo transfer—a critique of the factors involved in optimizing pregnancy success. In: Advances in Fertility and Reproductive Medicine. Proceedings of the 18th World Congress on Fertility and Sterility. International Congress Series Volume 1266, April 2004: 111-8
  36. Manna C, Patrizi G, Rahman A, Sallam H. Experimental results on the recognition of embryos in human assisted reproduction. Reprod Biomed Online. 2004 Apr;8(4):460-9
  37. Sallam HN, Sallam AN. LH/HCG as a monthly injectable contraceptive? Hum Reprod. 2004 Apr;19(4):1038
  38. Sallam HN, Sadek SS. Ultrasound-guided embryo transfer: a meta-analysis of randomized controlled trials. Fertil Steril. 2003 Oct;80(4):1042-6
  39. Sallam HN, Sadek SS, Agameya AF. Assisted hatching--a meta-analysis of randomized controlled trials. J Assist Reprod Genet. 2003 Aug;20(8):332-42
  40. Sallam HN, Ezzeldin F, Sallam A, Agameya AF, Farrag A. Sperm velocity and morphology, female characteristics, and the hypo-osmotic swelling test as predictors of fertilization potential: experience from the IVF model. Int J Fertil Womens Med. 2003 Mar-Apr;48(2):88-95
  41. Sallam HN, Agameya AF, Rahman AF, Ezzeldin F, Sallam AN. Impact of technical difficulties, choice of catheter, and the presence of blood on the success of embryo transfer--experience from a single provider. J Assist Reprod Genet. 2003 Apr;20(4):135-42
  42. Sallam HN, Saad-el-Din S. Power enough? Confidence intervals for uncertainty. Fertil Steril. 2003 Apr;79(4):1039-40
  43. Sallam HN. Embryo transfer – the elusive step. In: Progress in Obstetrics and Gynaecology (No. 15). Editor: John Studd, Churchill Livingstone, London, 2003: 363-80
  44. Sallam HN. The evidence-based practice of assisted reproduction. In: Recent Advances in Obstetrics and Gynaecology (No. 22). Editors: John Bonnar and William Dunlop, Royal Society of Medicine Press Ltd, London, 2003: 95-108
  45. Sallam HN, Agameya AF, Rahman AF, Ezzeldin F, Sallam AN. Ultrasound measurement of the uterocervical angle before embryo transfer: a prospective controlled study. Hum Reprod. 2002 Jul;17(7):1767-72
  46. Sallam HN. [The ancient Alexandria school of medicine] Gynecol Obstet Fertil. 2002 Jan;30(1):3-10. French
  47. Sallam H, Farrag A, Agameya A, Ezzeldin F, Eid A, Sallam A. The use of a modified hypo-osmotic swelling test for the selection of viable ejaculated and testicular immotile spermatozoa in ICSI. Hum Reprod. 2001 Feb;16(2):272-6
  48. Sallam HN, Farrag A, Agameya AF, Ezzeldin F, Sallam A. Factors affecting the success of intracytoplasmic sperm injection in cases of non-ostructive azoospermia. Reproductive Technologies. 2001;10(5):261-267
  49. Sallam HN, Sallam AN, Ezzeldin FE, Agamia AF, Abou-Ali AH. Minimal requirements for a successful outcome in anovulatory patients treated with human menopausal gonadotropins. Int J Fertil Women Med. 2000 Jul-Aug;45(4):285-91
  50. Sallam HN, Sallam A, Ezzeldin F, Agamia AF, Abou-Ali A. Reference values for the midluteal plasma progesterone concentration: evidence from human menopausal gonadotropin-stimulated pregnancy cycles. Fertil Steril. 1999 Apr;71(4):711-4
  51. Sallam HN, Abdel-Dayem A, Sakr RA, Sallam A, Loutfy I. Mathematical relationships between uterine contractions, cervical dilatation, descent and rotation in spontaneous vertex deliveries.  Int J Gynaecol Obstet. 1999 Feb;64(2):135-9
  52. Sallam HN. Cyclofenil and human reproduction. Assisted Reproduction. 1999 Feb;9(1):39-44
  53. Sadek IA, Ismail HM, Sallam HN and Salem M. Survey of hormonal levels in meat and poultry sold in Alexandria, Egypt. Eastern Mediterranean Health Journal 1998;4(2):239-43
  54. Sadek IA, Ismail HM, Sallam HN and Salem M. Some aspects of the use of oral contraceptives as growth-promoting agents in poultry. Eastern Mediterranean Health Journal. 1995; 1(2):241-7
  55. Toppozada M, Medhat I, Sallam H, Ismail AA, el-Badawy ES, Abd Rabbo S. Improving placental blood flow in pre-eclampsia with prostaglandin A1. Acta Obstet Gynecol Scand. 1992 Jan;71(1):22-7
  56. Medhat WM, Fahmy SI, Mortada MM, Sallam HN, Nofal LM, Nosseir SA, Aboulfotouh MA. Construction of a local standard symphysis fundal height curves for monitoring intrauterine fetal growth. J Egypt Public Health Assoc. 1991;66(3-4):305-31
  57. Sallam HN, Bashmi YA. A comparison of 2 methods for monitoring gonadotrophin therapy. Aust N Z J Obstet Gynaecol. 1989 May;29(2):160-4
  58. Sallam HN. Comparaison de deux méthodes de surveillance du traitement par les gonadotrophines humaines. Contraception Fertilité Sexualité 1985:13(1):19-27
  59. Souka AR, Kamel M, Einen MA, Saleh F, Sallam H. Vaginal administration of a combined oral contraceptive containing norethisterone acetate. Contraception. 1985 Jun;31(6):571-81
  60. Iddenden DA, Sallam HN, Collins WP. A prospective randomized study comparing fresh semen and cryopreserved semen for artificial insemination by donor. Int J Fertil. 1985;30(1):50, 55-6
  61. Hackeloer BJ, Sallam HN. Ultrasound scanning of ovarian follicles.
    Clin Obstet Gynaecol. 1983 Dec;10(3):603-20
  62. Saleh FM, Sallam HN, Abdel-Rahman H, Souka AR, El-Sahwi SY, Toppozada HK. Blood hormone levels in Egyptian women on norethisterone oenanthate. Contraception. 1983 Jul;28(1):41-51
  63. Sallam HN, Whitehead MI, Collins WP. Incidence of mature follicles in spontaneous and induced ovarian cycles. Lancet. 1983 Feb 12;1(8320):357
  64. Sallam H. Structural and biochemical changes during spontaneous and induced ovarian cycles. PhD Thesis, University of London, 1983
  65. Marinho AO, Sallam HN, Goessens LK, Collins WP, Rodeck CH, Campbell S. Real time pelvic ultrasonography during the periovulatory period of patients attending an artificial insemination clinic. Fertil Steril. 1982 May;37(5):633-8
  66. Marinho AO, Sallam HN, Goessens L, Collins WP, Campbell S. Ovulation side and occurrence of mittelschmerz in spontaneous and induced ovarian cycles. Br Med J (Clin Res Ed). 1982 Feb 27;284(6316):632
  67. Sallam HN, Marinho AO, Collins WP, Rodeck CH, Campbell S. Monitoring gonadotrophin therapy by real-time ultrasonic scanning of ovarian follicles. Br J Obstet Gynaecol. 1982 Feb;89(2):155-9
  68. Collins WP, Branch CM, Collins PO, Sallam HN. Biochemical indices of the fertile period in women. Int J Fertil. 1981;26(3):196-202.
     
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