Peter Mikus
Peter Mikus
Associate Professor

Department of Pharmaceutical Analysis and Nuclear Pharmacy
Faculty of Pharmacy, Comenius University
Slovak Republic

Education

2007 Assoc. Prof., Department of Pharmaceutical Analysis and Nuclear Pharmacy, Faculty of Pharmacy (FP), Comenius University (CU)
1998-1999 RNDr., Department of Analytical Chemistry, Faculty of Natural Sciences, Comenius University
1995-2002 Ph.D., Department of Analytical Chemistry, Faculty of Natural Sciences,
Comenius University
1990-1995 M.Sc., Department of Analytical Chemistry, Faculty of Natural Sciences, Comenius University  

 

Biography

Peter Mikus received his M.Sc. in Analytical Chemistry in 1995 from the Faculty of Natural Sciences Comenius University in Bratislava, Slovak Republic. He received his Ph.D. in Analytical Chemistry from the same Faculty in 2002 under the supervision of Prof. Dr. Dusan Kaniansky, an excellent analyst and expert in the field of instrumental development of capillary electomigration techniques. During his Ph.D. study, in 1997, Peter Mikus joined academic and research center, namely Consiglio Nazionale delle Ricerche, Istituto di Cromatografia in Rome, Italy. Here, he made research under the supervision of Prof. Dr. Salvatore Fanali, an expert in the field of advanced methodology and application of chiral capillary electomigration methods. From 2002 he worked at the Faculty of Pharmacy Comenius University (FP CU) as a teacher and research scientist. Peter Mikus received his Assoc. Prof. qualification in Pharmaceutical Chemistry from the Faculty of Pharmacy Comenius University in 2007. Currently, he is Associate Professor, since 2010 is the Head of the Department of Pharmaceutical Analysis and Nuclear Pharmacy FP CU, and since 2012 is the Director of the Toxicological and Antidoping Center FP CU, dealing with an implementation of innovative analytical methods into the advanced pharmaceutical and biomedical research.

Research Interest

Research interests of Peter Mikus include development of new progressive (chiral) capillary electrophoresis separation methods for the advanced pharmaceutical and biomedical analyses of drugs, their (bio)degradation products, and biomarkers. Within this field it is mainly (i) implementation and testing of new (chiral) buffer additives in the ITP and CZE systems (i.e. advanced separation mechanisms, such as countercurrent and carrier selector systems), (ii) proposal of the 2D capillary electrophoresis methods for the ultratrace analytes present in the multicomponent matrices (i.e. advanced sample preparation, such as on-line sample concentration and clean-up), and (iii) study of analytical possibilities of the hyphenated electrophoretic and detection techniques (i.e. advanced detection stage, such as spectral DAD, LIF, MS: QQQ, Q-TOF for decreasing the detection limits and/or enhancing the structural identification of the known as well as unknown analytes). Within the current research of his team, there are besides the advanced electrophoretic methods also advanced chromatographic ones (HPLC/2D HPLC-Q-TOF/QQQ). These novel methods are developed for the current pharmaceutical and biomedical research program of the Faculty of Pharmacy Comenius University and cooperating clinical institutions.

 

Professional Activities:

Awards:

  1. Awarded for the scientific literature by the Literary fund, Section for scientific literature and computational programs, per 2012 year

a.for the scientific literature in the category of natural and technical sciences
b.for the remarkable scientific citation response in the category of natural and medicinal sciences

  1. Awarded for the best poster presented at the international conference: 1st Caparica Christmas Conference On Sample Treatment, on December 8-10, 2014 in Lisbon (Veizerová, J. Piešťanský, K. Maráková, P. Mikuš, Mass spectrometry identification and determination of varenicline and 2-hydroxyvarenicline in human urine with on-line preparation by means of column coupled electrophoresis)
  2. Awarded for the best analytical innovation in 2011: Main Shimadzu award 2011 (presentation at the international scientific competition: J. Piešťanský, P. Mikuš, K. Maráková, L. Veizerová. Spojenie separačných techník izotachoforézy a kapilárnej zónovej elektroforézy s laserom indukovanou fluorescenčnou detekciou pre vysokocitlivé stanovenie chinínu v klinických matriciach, 63. Zjazd chemikov, Tatranské Matliare, 5. – 9. 9. 2011)

 

Publications

Publications, citations, conferences:

More than 155 of the publication outputs, including 1 foreign AAA monograph, 1 AAB monograph, 3 ABA publications (1 invited), 5 ABC publications, 60 ADC papers: scientific papers published in the international current content registered journals (including invited papers: J. Chromatogr. B, Electrophoresis, J. Pharm. Biomed. Anal.).
More than 276 citations in the [o1] category: citations in the international publications registered in the citation indexes. Presentations at national and international scientific seminaries, conferences and symposia (more than 70).

  1. Mikuš, Peter : Chiral capillary electrophoresis in current pharmaceutical and biomedical analysis [[hard copy  plus electronic]]. - 1. vyd. - Rijeka : InTech, 2012. - 182 s. [online] Lit. 485 ISBN 978-953-51-0657-9 URL: http://www.intechopen.com/books/chiral-capillary-electrophoresis-in-current-pharmaceutical-and-biomedical-analysishttps://stella.uniba.sk/epc/FA/2012/vtls000260466.pdf
  2. Mikuš, Peter  - Maráková, Katarína : Hyphenated electrophoretic techniques in advanced analysis. - 1. vyd. - Bratislava : KARTPRINT, 2012. - 217 s. Lit. 363 ISBN 978-80-89553-04-4
  3. Mikuš, Peter - Maráková, Katarína : Column coupling electrophoresis in biomedical analysis Lit. 141 In: Biomedical Engineering - from theory to applications. - Rijeka : InTech, 2011. - S. 81-130 [3.99AH]. - ISBN 978-953-307-637-9
  4. Melník, Milan [1,65 AH] - Mikuš, Peter [1,60 AH]: Structural aspects of platinum coordination complexes. - (Chemical Engineering Methods and Technology - Materials Science and Technologies) Lit. 9 In: Eds.: L. Varennikov, E. Yedemsky : Platinum: Compounds, Production and Applications. - New York : Nova Science Publishers, 2013. - S. 1-33 [3,25 AH]. - ISBN 978-1-62257-939-6
  5. Melník, Milan [1,81 AH] - Mikuš, Peter [1,80 AH]: Structural and stereoisomers in the chemistry of Ge, Sn and Pb complexes Lit. 392 In: Ed.: J.C. Taylor : Advances in Chemistry Research. Vol. 18. - New York : Nova Science Publishers, 2013. - S. 51-91 [3,61 AH]. - ISBN 978-1-62257-911-2
  6. Melník, Milan [1,20 AH] - Mikuš, Peter [1,17 AH]: Structural characterization of heterometallic PtAu complexes. - (Chemistry Research and Applications - Chemical Engineering Methods and Technology) Lit. 80 In: Eds.: A. Moliere, E. Vigneron : New Developments in Chromophore Research. - New York : Nova Science Publishers, 2013. - S. 187-243 [2,37 AH]. - ISBN 978-1-62417-154-3
  7. Melník, Milan [1,35 AH] - Mikuš, Peter [1,35 AH]: Structural characterization of heterometallic PtAg complexes. - (Chemistry Research and Applications - Chemical Engineering Methods and Technology) Lit. 95 In: Eds.: A. Moliere, E. Vigneron : New Developments in Chromophore Research. - New York : Nova Science Publishers, 2013. - S. 73-132 [2,70 AH]. - ISBN 978-1-62417-154-3
  8. Melník, Milan - Mikuš, Peter : Isomers in the chemistry of mercury organometallic and heterometallic complexes. - (Chemistry Research and Applications - Environmental Science, Engineering and Technology) Lit. 65 In: Eds.: K.H. Kim, R.J. Brown : Mercury - Sources, Applications and Health Impacts. - New York : Nova Science Publishers, 2013. - S. 67-86 [1,28 AH]. - ISBN 978-1-62257-721-1
  9. Melník, Milan [0,80 AH] - Mikuš, Peter [0,75 AH]: Structural characterization of heteronuclear PtCu complexes. - (Chemistry Research and Applications - Chemical Engineering Methods and Technology) Lit. 48 In: Eds.: A. Moliere, E. Vigneron : New Developments in Chromophore Research. - New York : Nova Science Publishers, 2013. - S. 281-312 [1,55 AH]. - ISBN 978-1-62417-154-3
  10. Melník, Milan - Mikuš, Peter : Structural aspects of mercury complexes. - (Chemistry Research and Applications - Environmental Science, Engineering and Technology)

 

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