Education

Biography

Dr Alexis´ PhD thesis focused on drug release and degradation mechanisms of biodegradable drug eluting stents. As a postdoctoral fellow at the Brigham and Women’s Hospital in the laboratory of Dr Omid Farokhzad and Research Affiliate at the Massachusetts Institute of Technology from 2006 to 2009 in the laboratory of Prof. Robert Langer, where he developed multiple polymeric nanoparticle technologies including targeted nanoparticles for cancer therapy, oral drug delivery, and vaccines. He has published 50 manuscripts and reviews, and 7 book chapters. Among these publications, his review published in Molecular Pharmaceutics has been listed as most accessed for the past seven years and three of his recent research from Clemson University and YachayTech have been highlighted as cover art and frontispiece. In addition to publications, he holds 18 intellectual properties, including 9 licensed to industry. He was listed in Nature Biotechnology as Top Translational Junior Faculty in 2013.

Research Interest

• Targeted nanoparticles for cancer therapy
• Oral drug delivery
• Vaccines

Scientific Activities

Employment History

Professional Activities

Memberships

• Member, Biomedical Engineering Society, BMES (2014-)
• Member, Society For Biomaterials, SFB (2009- 2012)
• Member, American Chemical Society, ACS (2008-2012)
• Member, Society of Chemical Industry, SCI (2004- )

Honors And Awards

• Third place at the Singapore Young Person’s Lecture Competition, Institute of Materials South East Asia (2004).
• Phage Display of Proteins and Peptides Training, Cold Spring Harbor Laboratory (2009)
• Most cited article in Chem Med Chem (2007)
• Most accessed article in Molecular Pharmaceutics (2008-2014)
• Cover Art in Particles and Particle Systems Characterization, Vol 30 (2013)
• ACS Nano Podcast of an interview with Dr. Anker and Alexis; Episode 67: ACS Nano; February 2013 "Managing Editor Heather Tierney highlights features and research content from Volume 7, Issue 2. In this episode we hear about monitoring pH-triggered drug release using radioluminescent nanocapsules. Featuring an interview with authors Frank Alexis and Jeffrey Anker."
• Listed in a Nature Biotechnology article as Top Translational Junior Faculty in 2013
• Frontispiece in Advanced Functional Materials, In Press (2014)
• Guest Speaker, Nanyang Technological University, Convocation 2015
• Guest Editor, Bioengineering, 2016
• Louis Stoke South Carolina Alliance for Minority Participation-Mentor of the Year 2016
• Editor, Bioegineering, 2017
• Recognition for exceptional service and support of PEER& WISE, 2017
• Editor, Journal of Biomedical Instrumentation and Applications, 2017

Publications

1. Kolishetti, N., Alexis, F., Pridgen, E., Farokhzad, O. C., Nanoplatform-Based Molecular Imaging, 1st edition (2011), John Wiley and Sons, Inc., Hoboken, NJ.
2. Rosen, Y., Mattix, Rao A., Alexis, F. Nanomedicine in Health and Disease, 1st edition (2011), Taylor and Francis Group, LLC, Boca Raton, FL.
3. Moore, T., Graham, E., Mattix, B., Alexis, F., Biomaterials Science: An Integrated Clinical and Engineering Approach, 1st edition (2012), Taylor and Francis Group, LLC, Boca Raton, FL.
4. Venkatraman, S.; Keith, K.; Rosen, Y.; Huang, Y.; Steele, T.W.J.; Alexis, F., Polymers for Vascular and Urogenital Applications, 1st edition (2012), Taylor and Francis Group, LLC, Boca Raton, FL.
5. Prior to Clemson N=3:
6. Alexis, F.; Zeng, J.; Wang, S., Gene Transfer: Delivery and Expression of DNA and RNA, A Laboratory Manual, 1st edition (2007), Cold Spring Harbor Laboratory Press, New York, NY.
7. Pridgen, E.; Alexis, F.; Farokhzad, O. C.; Langer, R., Methods in Bioengineering Book Series Nanoscale Bioengineering and Nanomedicine, 1st edition (2009), Artech House , Boston, MA.
8. Alexis, F.; Pridgen, E.; Langer, R.; Farokhzad, O. C., Handbook of Experimental Pharmacology 197, 1st edition (2010), Springer, Berlin, Germany.
9. Loo, S.C.J., Moore, T., Banik, B., Alexis, F., “Biomedical Applications of Hydroxyapatite Nanoparticles”, Current Pharmaceutical Biotechnology 11, 333-342 (2010).
10. Zha, L., Banik, B., Alexis, F., “Stimuli Responsive Nanogels”, Soft Matter 7, 5908-5916 (2011).
11. Stone, R., Willi, T.J., Mefford, T., Rosen, Y., Alexis, F., “Targeted Magnetic Hyperthermia”, Therapeutic Delivery 2, 815-838 (2011).
12. Banik, B., Alexis, F., “Spatial Functionalization of Polymeric Films”, Cover page of Biomaterials Forum 33, 3, (2011).
13. Xiao, Z., Levy-Nissenbaum, E., Alexis, F., Lupták, A., Teply, B.A., Chan, J.M., Shi, J., Digga, E., Cheng, J., Langer, R., Farokhzad, O.C., “Engineering of Targeted Nanoparticles for Cancer Therapy Using Internalizing Aptamers Isolated by Cell-Uptake Selection”, ACS Nano 6, 696-704 (2012).
14. Chen, H., Colvin, D. C., Qi, B., Moore, T., He, J., Mefford, O. T., Alexis, F., Gore, J. C., Anker, J. N., “Magnetic and optical properties of multifunctional core-shell radioluminescence nanoparticles”, J. Mat. Chem. 22, 12802-12809 (2012).
15. Chen, H., Moore, T.; Qi, B.; Colvin, D.C.; Jelen, E.; Hitchcock, D.A.; He, J.O.; Mefford, T.; Gore, J.C.; Alexis, F.; Anker, J.N. “Monitoring pH-triggered Drug Release from Radioluminescent Nanocapsules with X-ray Excited Optical Luminescence.” ACS Nano, 7, 1178-1187 (2013).
16. Podila, R.; Moore, T.; Alexis, F.; Rao, M.A. “Graphene coatings for enhanced hemo-compatibility of nitinol stents”. RSC Advances , 3, 1660-1665 (2013).
17. Podila, R.; Moore, T.; Alexis, F.; Rao, M.A. “Graphene Coatings for Biomedical Implants”. Journal of Visualized Experiments, 73, e50276 (2013)
18. Moore, T.L., Pitzer, J., Podila, R., Wang, X., Lewis, R.L., Grimes S.W., Wilson, J.R., Skjervold, E., Brown, J., Rao, A., Alexis, F., “Polymer Coated Carbon Nanotubes to Safely Deliver Drugs”, Particles and Particle Systems Characterization, 30, 299 (2013).
19. Moore, T.L., Pitzer, J., Podila, R., Wang, X., Lewis, R.L., Grimes S.W., Wilson, J.R., Skjervold, E., Brown, J., Rao, A., Alexis, F. Cover Art in Particles and Particle Systems Characterization, Vol 30 (2013).
20. Chi, A.; Clayton, K.; Burrow, T.J.; Lewis, R.; Luciano, D.; Alexis, F.; D’hers, S.; Elman, NM; “Intelligent drug-delivery devices based on micro- and nanotechnologies”. Therapeutic Delivery, 4, 77-94 (2013)
21. Pridgen, E.M., Alexis, F., Kuo, T.T., Levy-Nissenbaum, E., Blumberg, R.S., Langer, R., Farokhzad, O.C., “Transepithelial Transport of Fc-Targeted Nanoparticles Across the Intestinal Epithelium Barrier by the Neonatal Fc Receptor for Oral Delivery”, Science Translational Medicine, 5, 213 (2013).
22. Mattix, B.; Poole, T.; Casco, M.; Uvarov, O; Visconti, R. P.; Simionescu, D.; and Alexis F. “Small Diameter Vascular Grafts: Replacement Strategies, Maturation Techniques, and Challenges”, Journal of Tissue Science & Engineering, 4, 1 (2013).
23. Mattix, B., Moore, T., Uvarov, O., Pollard, S., O'Donnell, L., Park, K., Horne, D., Dhulekar, J., Olsen, T., Duong, N.; Burg, K.; Kraveka, J., Alexis, F. “Effects of Polymeric Nanoparticle Surface Properties on Interaction with Brain Tumor Environment for Drug Delivery Applications”. NanoLife, 3, 1343003 (2013)
24. Mattix, B.; Olsen, T.R.; Moore, T; Casco, M.; Simionescu, D.; Visconti, R; Alexis, “Accelerated Iron Oxide Nanoparticle Degradation Mediated by Polyester Encapsulation for Tissue Engineering Into Cellular Spheroids”. Adv. Funct. Mat., 24, 800-807 (2014)
25. Chen, H.; Qi, B.; Moore, T.; Colvin, D.C.; Gore, J.C.; Alexis, A.; Mefford, O.T.; and Anker, J.N.” Synthesis of brightly PEGylated luminescent magnetic up-conversion nanophosphors for deep tissue and dual MRI imaging. Small, 10, 160-168 (2014).
26. Mattix, B.; Olsen, T.R.; Gu, Y.; Casco, M.; Herbst, A.; Simionescu, D., Visconti, R. P., Kornev, K.G.; and Frank Alexis, “Biological Magnetic Cellular Spheroids as Building Blocks for Tissue Engineering”, Acta Biomateriala, 10, 623-629 (2014).
27. Mattix, B.; Olsen, T.R.; Casco, M.; Reese, L.; Poole, L.T.; Zhang, J.; Visconti, R.; Simionescu, A.; Simionescu, D.; Alexis, F. “Janus Magnetic Cellular Spheroids for Vascular Tissue Engineering”, Biomaterials, 35, 949-960 (2014).
28. Moore, T.L., Podilakrishna, R.; Rao, A.; Alexis, F. “Systemic Administration of Polymer-Coated Nano-Graphene to Deliver Drugs to Glioblastoma”, Particle and Particle Systems Characterization, In Press, Covert Art, (2014).
29. Moore, T.L.; Grimes, S.W.; Lewis, R.L.; Alexis, F.“Multilayered Coated Carbon Nanotube to Deliver Dasatinib”. Mol. Pharm., 11, 276-282 (2014).
30. Moore, T.; Chen, H.; Morrison, R.; Wang, F.; Anker, J.N., Alexis, F. “Nanotechnologies for Non-invasive Measurement of In Vivo Drug Release”. Mol. Pharma., 11, 24-39 (2014)
31. Ilyinskii, P.O., Roy, C.J.; O’Neil, C.P.; Browning, E.A.; Pittet, L.A.; Altreuter, D.H.; Alexis, F.; Tonti, E.; Shi, J.; Basto, P.A., Radovic-Moreno, A.F.; Iannacone, Langer, R.S., Farokhzad, O.C.; von Andrian,U.H.; Johnston, L.P.M.; and Kishimoto, T.K. “Adjuvant-Carrying Synthetic Vaccine Particles Augment the Immune Response to Encapsulated Antigen and Exhibit Strong Local Immune Activation without Inducing Systemic Cytokine Release”. Vaccine, 32, 2882-2895 (2014).
32. Alexis, A.; and Anker, J.N.”Theranostic nanotechnologies: moving beyond imaging the localization of the drug”. Therapeutic Delivery (Editorial), 5, 97-100 (2014).
33. Chen H, Sulejmanovic D, Moore T, Colvin DC, Qi B, Mefford OT, Gore JC, Alexis F, Hwu SJ, Anker JN. “Iron-Loaded Magnetic Nanocapsules for pH-Triggered Drug Release and MRI Imaging.” Chem Mater., 26, 2105-2112 (2014).
34. Chen H, Qi B, Moore T, Wang F, Colvin DC, Sanjeewa LD, Gore JC, Hwu SJ, Mefford OT, Alexis F, Anker JN. “Multifunctional Yolk-in-Shell Nanoparticles for pH-triggered Drug Release and Imaging.” Small, 10, 3364-3370 (2014) Alexis F. “Nano-polypharmacy to treat tumors: coencapsulation of drug combinations using nanoparticle technology.”Mol Ther., Commentary Article, 22, 1239-1240 (2014)
35. Olsen, R.T.; Alexis, F.; “Bioprocessing of Tissues using Cellular Spheroids”, Journal of Bioprocessing and Biotechniques, Editorial, 4, e112 (2014) Pridgen EM, Alexis F, Farokhzad OC. “Polymeric Nanoparticle Technologies for Oral Drug Delivery.” Clin Gastroenterol Hepatol., 12, 1505-1510 (2014)
36. Moore, T.L.; Wang, F.; Chen, H.; Grimes, S.W.; Anker, J.N.; Alexis, F.; "Polymer Coated Radioluminescent Nanoparticles for Imaging Drug Delivery into Cells". Adv. Funct. Mat., 37, 5815-5823 (2014).
37. Olsen, T. R., Mattix, B., Casco, M.; Herbst, A., Williams, C., Tarasidis, A., Evans, G., Jenkins, L., McMahan, C.L., Simionescu, D., Visconti, R.P., Alexis, F.; Processing cellular spheroids for histological examination. Journal of Histotechnology, 37, 138-142 (2014)
38. Olsen, T. R., Casco, M.; Mattix, B., Herbst, A., Williams, C., Tarasidis, A., Evans, G., Jenkins, L., McMahan, C.L., Simionescu, D., Visconti, R.P., Alexis, F. “Preparing and Processing Complex Tissue Constructs Composed of Cellular Spheroids”. Journal of Cytology and Tissue Biology. 1: 002 (2014)
39. Olsen, T.R., Davis, L.; Nicolau, SE; Duncan, C.C.; Whitehead, D.C.; Van Horn, B.A.; and Alexis, F.; “Non-Invasive Deep Tissue Imaging of Iodine Modified Poly(caprolactone-co-1-4-oxepan-1,5-dione) Using X-Ray”. Acta Biomaterialia, 20, 94-103 (2015).
40. Pridgen EM, Alexis F, Farokhzad OC. “Polymeric Nanoparticle Drug Delivery Technologies for Oral Delivery Applications.” Expert Opinion Drug Delivery., 12, 1459-1473 (2015).
41. Nicolau, SE; Davis, L.; Duncan, C.C.; Olsen, T.R., Alexis, F.; Whitehead, D.C.; Van Horn, B.A.. “An Oxime Graft Strategy for Iodinated Poly(epsilon-caprolactone) X-ray Opaque Materials. Journal of Polymer Science: Polymer Chemistry Part A, 53, 2421-2430 (2015).
42. Campbell, McKenzie L. Guerra, Fernanda. D.;Dhulekar, Jhilmil; Alexis, Frank; Whitehead, Daniel. C.; “Target-Specific Capture of Enviromentally Relevant Gaseous Aldehydes and Carboxylic Acids with Functional Nanoparticles.” Chemistry, 21, 14834-42 (2015).
43. Timothy R. Olsen, Megan Casco, Austin Herbst, Grace Evans, Taylor Rothermel, Lauren Pruett, Jared Reid, Kelly Berry, Michael P. Jaeggli, Dan T. Simionescu, Richard P. Visconti, and Frank Alexis.” Longitudinal Stretching for Maturation of Vascular Tissues Using Magnetic Forces”. Bioengineering, 3(4), 29 (2016).
44. Casco, M., Martin, J., Zhang, G., Alexis, F. “Singapore Study Abroad Program: Cross-Cultural and Global Interdependency Development in STEM Undergraduate Students”, Education, 137 (3), 249-256 (2017)
45. Brooke A. Van Horn, Lundy L. Davis, Samantha E. Nicolau, Emma E. Burry, Victoria O. Bailey, Fernanda D. Guerra, Frank Alexis, and Daniel C. Whitehead. "Synthesis and Conjugation of a Triiodohydroxylamine for the Preparation of Highly X-ray Opaque Poly(epsilon-caprolactone) Materials". J. Polym. Sci., Part A: Polym. Chem., 55, 787–793 (2017).
46. Fernanda D. Guerra; Doug Smith Frank Alexis; Daniel C. Whitehead, “A survey of VOC emissions from rendering plants.” Aerosol and Air Quality Research, 17: 209–217 (2017).
47. Casco, M., Olsen, T. R., Herbst, A., Grace Evans, Taylor Rothermel , Lauren Pruett Simionescu, D., Visconti, R. P., Alexis, F. “Iron Oxide Nanoparticles Stimulates Extra-Cellular Matrix Production into Cellular Spheroids”, Bioengineering, 2017, 4, 4.
48. Guerra, F. D.; Whitehead, Daniel. C., Alexis, F. ”Nanotechnology in Environmental Remediation: Materials and Applications”, Submitted (2017).
49. Guerra, Fernanda. D.; Campbell, McKenzie L.; Whitehead, Daniel. C.; Alexis, Frank, “Tunable Properties of Functional Nanoparticles for Efficient Capture of VOCs” Submitted (2017)
50. Guerra, Fernanda. D.; Whitehead, Daniel. C.; Alexis, Frank; "Gaseous Capture using Amine-functionalized Cellulose", Submitted (2017)
51. Prior to Clemson N=14:
52. Alexis, F., Rath, S. K., Boey, F.Y.C., Venkatraman, S.,"Study of the Initial Stages of Drug Release from a Degradable Matrix of Poly (d,l-lactide-co- glycolide)", Biomaterials 25, 813-821 (2004).
53. Alexis, F., Rath, S. K, Venkatraman, S., “In Vitro Study of Release Mechanisms of Paclitaxel and Rapamycin from Drug-Incorporated Biodegradable Stent”, Journal of Controlled Release 98, 67-74 (2004).
54. Alexis, F., Rath, S. K., Boey, F.Y.C., Venkatraman, S., “Controlled drug release of bioerodible polymers: effect of drug type and composition”, Journal of Controlled Release 102, 333-344 (2005).
55. Alexis, F., "Factors Affecting Degradation and Drug Release Mechanisms of Bioerodible Polymers", Polymer International 54, 36-46 (2005).
56. Tang, G.P., Zeng, S., Alexis, F., Yang, Y.Y., Wang, S., “Low Molecular Weight Polyethylenimine Copolymerized with B-cyclodextrin for Gene Delivery”, Journal of Gene Medicine 8, 736-744 (2006).
57. Alexis, F., Rath, S. K., Gan, L-H., Venkatraman, S.,”Some Insight into Hydrolytic Scissions Mechanisms in Bioerodible Polyesters”, Journal of Applied Polymer Science 102, 3111-3117 (2006).
58. Alexis, F., Lo, S.L., Wang, S., “Covalent Attachment of Low Molecular Weight Polyethylenimine Improves Tat-Peptide Mediated Gene Delivery", Advanced Materials 18, 2174-2178 (2006).
59. Zhang, L., Radovic-Moreno, A., Alexis, F., Gu, F.X., Basto, P., Langer, R, Farokhzad, O. C., “Co-Delivery of Hydrophobic and Hydrophilic Drugs from Nanoparticle-Aptamer Bioconjugates”, ChemMedChem. 2, 1268-1271 (2007).
60. Gu, F.X., Karnik, R., Wang, A. Z., Alexis, F., Levy-Nissenbaum, E., Hong, S., Langer, R., Farokhzad, O. C.,” Targeted Nanoparticles for Cancer Therapy”, NanoToday 2, 14-21 (2007).
61. Alexis, F., Basto, P., Levy-Nissenbaum, E., Radovic-Moreno, A., Zhang, L., Langer, R., Molnar, L., Farokhzad, O. C.,”HER-2 Targeted Nanoparticle-Affibody Bioconjugates for Breast Cancer Therapy“, ChemMedChem. 3, 1839-1843 (2008).
62. Zhang, L., Chan, J. M., Gu, F.X., Rhee, J-W., Wang, A.Z., Radovic-Moreno, A., Alexis, F., Langer, R, Farokhzad, O. C., “Self-Assembled Lipid-Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform”, ACS Nano 2, 1696-1702 (2008).
63. Alexis, F., Radovic-Moreno, A., Rhee, J-W, Richie, J. P., Langer, R., Farokhzad, O. C., "New Frontiers in Nanotechnology for Cancer Treatment", Journal of Urological Oncology 26. 74-85 (2008).
64. Wang, A. Z., Bagalkot, V., Vasilliou, C., Gu, F.X., Alexis, F., Zhang, L., Shaikh M., Yuet, K. , Cima, M., Langer, R., Farokhzad, O. C., Kantoff, P.W., Bander, N.H., Jon, S., Farokhzad, O. C., "Superparamagnetic Iron Oxide Nanoparticle-Aptamer Bioconjugates for Combined Prostate Cancer Imaging and Therapy”, ChemMedChem. 9, 1311-1315 (2008).
65. Alexis, F., Pridgen, E., Langer, R., Farokhzad, O. C., "Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles", Molecular Therapeutics 5, 505-515 (2008).
66. Conference Proceedings: (Peer Reviewed)
67. Banik, B.L., Rogers, M., Dhulekar, J., Moore, T.L., Alexis, F., “Synthesis and Testing of Biomolecules to Target Bone”, Proceedings of the National Conference of Undergraduate Research, Ithaca College, Ithaca, NY, (2011).
68. Banik, B.L., Rogers, M., Dhulekar, J., Moore, T.L., Alexis, F., “Synthesis and Testing of Biomolecules to Target Bone”, Proceedings of the ACC Meetings of Minds, University of Miami, Miami, FL, (2011).
69. Keith, K., Mattison, S., Collier, M., Lewis, R., Alexis, F. “Testing Chemotherapeutic Drugs for Synergistic Toxicity Using Several Cancer Cell Lines”, Proceedings of the ACC Meetings of Minds, University of Miami, Miami, FL, (2011).
70. Wright-Walker, C. J., DesJardins, J. D., Alexis, F., LaBerge, M., “Tribological Evaluation of a Drug Enriched Ultra-High Molecular Weight Polyethylene for Enhanced Total Joint Replacement Bearing Surface Functionality”, Proceedings of the Society For Biomaterials Meeting, Orlando, FL, (2011).
71. Mattix, B., Reese, L., Pollard, S., Anderson, J., Carpenter, K., Davda, L., Breece, J., Alexis, F.”Effects of Polymeric Nanoparticle Surface Properties on Interaction with Brain Cancer Cells”, Proceedings of the Southeast Regional IDeA Meeting, New Orleans, LA, (2011).
72. Mattix, B., Uvarov, O., Willi, T., Reese, L., Pollard, S., Frankel, B., Alexis, F. “ Effects of Polymeric Nanoparticle Surface Properties on Interaction with Brain Tumor Environment”, Proceedings of the SC INBRE Scientific Symposium, Columbia, SC, (2012).
73. Mattix, B., Reese, L., Poole, T., Visconti, R., Simionescu, D., Simionescu, A., Jenkins, L., Bruce, T., Alexis, F. “Assembly of Engineered Blood Vessels Using Magnetic Forces.” Proceedings of the SC Project for Organ Biofabrication Scientific Symposium, Columbia, SC, (2012).
74. Poole, T., Mattix, B, Reese, L., Alexis, F. “Magnetic Spheroids For Tissue Engineering Applications.” Proceedings of the National Conference on Undergraduate Research, Weber State University, Ogden, Utah, (2012).
75. Wright-Walker, C. J.; Golightly, C. E.; Alexis, F.; DesJardins, J. D.; LaBerge, M.; “Tribological Evaluation of a Drug Enriched Ultra-High Molecular Weight Polyethylene for Enhanced Total Joint Replacement Bearing Surface Functionality”; Proceedings of the Society For Biomaterials Conference, New Orleans, (2012).
76. Moore, T. L.; Stoner, B.; Morrison, R.; Simionescu, A.; Simionescu, D.; Recknor, C.; Alexis, F.; “Targeted, Multifunctional Nanoparticles for Controlled Delivery of Anabolic Bone Therapy Drugs”. Proceedings of the Society For Biomaterials Conference, New Orleans, (2012).
77. Mattix, B.; Poole, T.; Casco1, M.; Visconti, R.; Simionescu, D.; Simionescu, A.; Alexis, F.; “Spatial Control of Magnetic Nanoparticles Integrated with Cellular Spheroids as Tissue Engineered Building Blocks”. Proceedings of the Society For Biomaterials Conference, New Orleans, (2012).
78. Dawson, B.; “Periorbital Implant for Treatment of Cytomegalovirus”. Proceedings of the South Carolina-Louis Stoke Alliance for Minority Participation (LSAMP) Conference, Columbia, (2012).
79. Horne, D.; “Effects of Polymeric Nanoparticle Surface Properties on Interaction with Brain Tumor Environment”. Proceedings of the South Carolina-Louis Stoke Alliance for Minority Participation (LSAMP) Conference, Columbia, (2012).
80. Alexis, F.; “Polymer Coated CNTs to Safely Delivery Drugs”. Proceedings of the ACS SERMACS Meeting, Raleigh, (2012).
81. Uvarov, O.; Mattix, B.; Pollard, S.; O’Donnel, L.; Horne, D.; Dhulekar, D.; Frankel, B. Alexis, F.”An Investigation of Functionalized Nanoparticles Interactions with Brain Cancer Cells” .I”. Proceedings of the ICMAT, Singapore, (2012)
82. Moore, T.; Morrison, R.; Stoner, B.; Simionescu, A.; Simionescu, D.; Recknor, C.; Alexis, F. “Targeted, Multifunctional Nanoparticles for Controlled Delivery of Anabolic Bone Therapy Drugs.”Proceedings of the Biomedical Engineering Society Annual Meeting, Atlanta, (2012).
83. Mattix, B.; Poole, T.; Casco1, M.; Visconti, R.; Simionescu, D.; Simionescu, A.; Alexis, F. “Spatial Control of Magnetic Nanoparticles Integrated with Cellular Spheroids as Tissue Engineered Building Blocks”. Proceedings of the Biomedical Engineering Society Annual Meeting, Atlanta, (2012).
84. Chen H., Moore T., Qi B., Colvin D.C., Jelen E., Hitchcock, D., He J., Mefford O.T., Gore J.C., Alexis F., Anker J.N., “Monitoring pH-triggered drug release from radioluminescent nanocapsules with X-ray excited optical luminescence,” Proceedings of the ACS SERMACS Meeting, Raleigh, (2012).
85. Alexis, F. “Drug Delivery and Imaging Technologies Using X-Ray”, ICMAT, Singapore, (2013).
86. Olsen, T., Alexis F.; “Cellular Spheroid Fusion Using Magnetic Forces to Fabricate a Vascular Tissue”, Society For Biomaterials, (2013).
87. Olsen, T., Casco, M., Simionescu, D., Visconti, R., Alexis, F.”Accelerating Cellular Spheroid Fusion Using Magnetic Forces to Fabricate a Vascular Tissue "Blood Vessel Tissue Engineering", Accepted. Biomedical Engineering Society, San Antonio, Accepted (2014).
88. Olsen, T., Whitehead, D., Van Horn, B., Alexis, F. ”Non-Invasive Deep Tissue Imaging of Polymer Degradation Using X-Ray”, Accepted. Biomedical Engineering Society, San Antonio, Accepted (2014).
89. Michael Taylor, K B. Acampora, Joel T. Corbett, Frank Alexis, Bradley R. Johns and Jason M. Olbrich Viscoprene drug delivery system for the sustained release of disulfiram for treatment of alcohol use disorder. -World Biomaterials Congress 2016, Boston (2016).