Moses Rodriguez is a nationally recognized multiple sclerosis expert. He holds the academic rank of Professor of Neurology and Immunology and the Mildred A. and Henry Uihlein II Professorship in Medical Research at Mayo Clinic College of Medicine. He recently received the highest award at Mayo Clinic – the Distinguished Investigator Award.

Dr. Rodriguez earned his B.A. and M.D. degrees at Northwestern University. After residency in neurology at Mayo Graduate School of Medicine, he served as a trainee at the National Institutes of Health and completed fellowships in neuropathology at the University of California, San Diego, and at Scripps Research Institute.

His research has focused on developing methods to reverse the deterioration of the central nervous system in multiple sclerosis, a debilitation by the destruction of the multi-layered sheath that surrounds nerve fibers called myelin.  Remyelination, in essence, is the restoration of this protective tissue. Dr. Rodriquez and his research colleagues have identified human antibodies that stimulate remyelination in laboratory mice. Their findings have formed of the recently completed phase I clinical trial,  the first remyelination clinical trial in humans (results to be made public in Fall 2014). He is also a member of a Mayo Clinic research team that identified the human-produced hormone Interleukin-6 that may prolong neuron (brain cell) life. Dr. Rodriguez holds 14 U.S. patents related to his fundamental medical discoveries and has authored more than 400 peer reviewed papers. Currently the principal investigator of five grants, he directs a prestigious National MS Society Center of Excellence and the Mayo Center for Multiple Sclerosis and Central Nervous System Demyelinating Diseases Research and Therapeutics.

A talented musician, Dr. Rodriguez is co-director of Trombones Anonymous, a regional trombone choir for which he has written over 250 original arrangements.  He enjoys bass fishing and camping with his family in the Boundary Waters Canoe Area in Northern Minnesota.


Moses Rodriguez, MD

Professor of Neurology


  • : (507) 284-3734

  • DEPARTMENTMayo Medical School