1. Dollé L, Bin Gao. Pharmacological chaperone therapies: can aldehyde dehydrogenase activator make us healthier?Journal of Hepatology 2015Febdoi:10.1016/j.jhep.2015.02.011;IF=10.401
  2. Best J, Manka P, Syn WK, Dollé L, van Grunsven LA, and Canbay A. Role of liver progenitors in liver regeneration.Hepatobiliary Surgery and Nutrition journal2015Feb;4(1):48-58.First IF this year
  3. Dollé L, Boulter O, Leclercq IA, and van Grunsven LA. Next generation of ALDH substrates and their potential to study maturational lineage biology in stem and progenitor cells. Am. J. Physiol-GastrointestinLiver Physiol 2015April 308 (7) G573-G578 doi: 10.1152/ajpgi.00420.2014 .IF=3.737
  4. Verhulst S, van Grunsven LA*, and Dollé L*.Advances in Hepatic Stem/Progenitor Cell Biology. EXCLI Journal2015Jan14:33-47IF=1.923; *equal contribution
  5. Dollé L, Theise ND,Schmelzer E, Boulter O, Gires O, and van Grunsven LA. EpCAM and the Biology of Hepatic Stem/Progenitor Cells. Am. J. Physiol-Gastro Liver 2014 Dec 4:ajpgi.00069.2014. doi: 10.1152/ajpgi.00069.2014. [Epub ahead of print. IF=3.737
  6. Gevaert E, Dollé L, Billiet T, Dubruel P, van, Grunsven LA, van Apeldoorn A, Cornelissen R. High throughput micro-well generation of hepatocyte micro-aggregates for tissue engineering. PloS One 2014Aug 18; 9(8):105171. IF=3.53
  7. Coombes J, Swiderska-Syn M, Dollé L, Reid D, Eksteen B, Claridge L. et al. Osteopontin neutralization abrogates the liver progenitor cell response and fibrogenesis in mice. Gut 2014Jun 5 doi:10.1136/gutjnl-2013-306484.IF=13.319
  8. Paganelli M, Nyabi O, Sid B, Evraerts J, El Malmi I, Heremans Y, Dollé L, et al. Downregulation of Sox9 Expression Associates with Hepatogenic Differentiation of Human Liver Mesenchymal Stem/Progenitor Cells. Stem Cells Dev 2014.
  9. Best J, Dollé L, Manka P, Coombes J, van Grunsven LA, Syn WK. Role of liver progenitors in acute liver injury. Front Physiol 2013;,4:258 doi:10.3389/fphys.2013.00258.First IF in 2015
  10. Theise ND, Dollé L, Kuwahara R. Low hepatocyte repopulation from stem cells: a matter of hepatobiliary linkage not massive production. Gastroenterology 2013;145:253-254.IF=13.926
  11. Schroyen B, Guimaraes EL, Dollé L, Coulon S, Empsen C, Nyssen M, Geerts A, et al. Leptin-mediated reactive oxygen species production does not significantly affect primary mouse hepatocyte functions in vitro. Eur J Gastroenterol Hepatol 2012;24:1370-1380.IF=1.915
  12. Guimaraes EL, Best J, Dollé L, Najimi M, Sokal E, van Grunsven LA. Mitochondrial uncouplers inhibit hepatic stellate cell activation. BMC Gastroenterol 2012;12:68.IF=2.11
  13. Kaldenbach M, Giebeler A, Tschaharganeh DF, Erschfeld S, Wasmuth HE, Dollé L, Floege J, et al. Hepatocyte growth factor/c-Met signalling is important for the selection of transplanted hepatocytes. Gut 2012;61:1209-1218.IF=10.732
  14. Dollé L, Streetz KL, van Grunsven LA. Sharpen your look on liver progenitor cells. Hepatology 2012;55:319-321. IF=12.002
  15. Dollé L, Best J, Empsen C, Mei J, Van Rossen E, Roelandt P, Snykers S, et al. Successful isolation of liver progenitor cells by aldehyde dehydrogenase activity in naive mice. Hepatology 2012;55:540-552.IF=12.002
  16. Derycke L, Stove C, Vercoutter-Edouart AS, De Wever O, Dollé L, Colpaert N, Depypere H, et al. The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells.Int J Dev Biol 2011;55:835-840. IF=2.866
  17. Vanhooren V, Dewaele S, Kuro OM, Taniguchi N, Dollé L, van Grunsven LA, Makrantonaki E, et al. Alteration in N-glycomics during mouse aging: a role for FUT8. Aging Cell2011;10:1056-1066.IF=6.265
  18. Thoen LF*, Guimaraes EL*, Dollé L, Mannaerts I, Najimi M, Sokal E, van Grunsven LA. A role for autophagy during hepatic stellate cell activation.J Hepatol2011;55:1353-1360.IF=9.264*equal contribution.
  19. Dollé L, Best J, Mei J, Al Battah F, Reynaert H, van Grunsven LA, Geerts A. The quest for liver progenitor cells: a practical point of view. J Hepatol2010;52:117-129.IF=9.334


  1. Dollé L, De La Serre C, Rogiers V, and van Grunsven LA.Dietary emulsifiers simplify our daily-life but at what cost?Journal of Hepatology 2015submitted
  2. Best J, Verhulst S, van Hul N, Syn WK, Heindryckx F, Reynaert H, Peeters L, Van Vlierberghe H, Hellemans KH, Leclercq IA,  van Grunsven LA*and Dollé L*.Anti-TNF-strategies ameliorate the ductular reaction in murine biliary disease, while impairing liver regeneration after murine parenchymal injury.Gut 2015 submitted.*equal contribution
  3. Govaere, JWouters, MPetz, YP Vandewynckel, K Van den Eynde, A Van den broeck, L Dollé, LGremeaux, A Ceulemans, FNevens, L van Grunsven, BTopal, H Vankelecom, GGiannelli, H Van Vlierberghe, WMikulits, M Komuta, and T Roskams. Side Population analysis identifies a role for laminin-332 in maintaining stemness in the human hepatic cancer stem cell niche.Journal of Hepatology2015submitted.

Paper in preparation

  1. Dollé L., Verhulst S., Mannaerts I., Guimaraes EL, Thoen LF, El Taghdouini A., van Grunsven LA. Role for Aldehyde Dehydrogenase Activity during Hepatic Stellate Cell Activation.In preparation.
  2. Van Hul N*, Espanol-Suner R*, Sempoux C., Dollé L., van Grunsven LA, Lemaigre F., Leclercq IA. Discrepancies between widely used mouse models of liver progenitor cells: comparative study between CDE- and DDC-induced chronic liver injuries. * equal contribution. In preparation.

MainInternational collaborators

  • Dr. Luke Boulter (MRC Human Genetics Unit MRC IGMM, University of Edinburgh Western General Hospital, Edinburgh, Scotland);
  • Prof. Dr. Ali Canbay (Department of Gastroenterology and Hepatology, University Hospital Essen, University Duisburg-Essen, Essen, Germany);
  • Prof. Dr. Patrice Cani, University of Pharmacy and Biomedical Sciences (FSAB), Université catholique de Louvain (UCL), Brussel, Belgium);
  • Prof.Olivier Gires (Department of Otorhinolaryngology, Head and Neck Surgery, Grosshadern Medical Center, Ludwig-Maximilians-University of Munich, Munich, Germany);
  • Prof. Dr. Annette Gouw (Department of Pathology and Medical Biology, University Medical Center Groningen, Nederland’s);
  • Dr. Karine Hellemans (Unit Diabetes Pathology & Therapy, Diabetes Research Center, VUB, Brussels, Belgium);
  • Prof. Dr. Isabelle A. Leclercq, (Laboratory of Hepato-Gastroenterology, Institut de Recherche Expérimentale et Clinique-RECUniversité catholique de Louvain UCL, Brussels, Belgium);
  • Prof. Dr. Mustapha Najimi (Institut de recherche expérimentale et clinique (IREC) Université catholique de Louvain (UCL), Brussel, Belgium) ;
  • Dr Pr. Mina Komuta (Hepato-Biliary-Pancreas pathology Service d’Anatomie pathologique, Cliniques universitaires Saint-Luc, UCL, Belgium);
  • Dr. Ray Kuwahara (Kurume University School of Medicine, Department of Medicine, Division of Gastroenterology, Kurume Fukuoka, Japan);
  • Prof. Dr. LolaM.Reid, (Department of Cell and Molecular Physiology, University of North Carolina School of Medicine, NC, US);
  • Prof. Vera Rogiers (Department In vitro Toxicology and Dermato-Cosmetology, Faculty of Medicine and Pharmacy, VUB, Brussels, Belgium)
  • Prof. Eva Schmelzer (McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, US);
  • Prof. Christine Sempoux (Department of Pathology, Faculté de Biologie et Médecine, Quartier UNIL-CHUV, Lausanne, Switzerland)
  • Prof. Dr. Wing-Kin Syn (Institute of Hepatology, University of London, UK);
  • Prof. Dr. Neil D. Theise, (Beth Israel Medical Center of Albert Einstein College of Medicine, NYC, US);
  • Prof. Hugo Vankelecom (Department Development and Regeneration, Lab Tissue Plasticity, Leuven, Belgium);
  • Prof. Dr. George Yeoh, (Department of Liver Disease & Carcinogenesis, Center for Medical Research, University of Western Australia, Crawley, Australia)


Dollé Laurent

Assistant Research Professor


  • : 0468160054

  • DEPARTMENTDepartment of Biomedical Sciences
    University Brussels (VUB)
  • COUNTRY Belgium