Publications

1. GUAN**, X. 2014. The CNS glucagon-like peptide-2 receptor in the control of energy balance and glucose homeostasis. Am J Physiol Regul Integr Comp Physiol. 307(6):R585-96. Epub 2014 Jul 2. (** denotes the corresponding author). Invited Review.
2. Shi, X., X. Li, Y. Wang, F. Zhou, B. Chang, D. Li, M. Fukuda, J. Zhao, D. Burrin, L. Chan, and X. GUAN**. 2013. Central GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons. Cell Metab. 18: 86-98. (** denotes the corresponding author). Article featured in this issue.
3. GUAN,** X., X. Shi, X. Li, B. Chang, Y. Wang, D. Li., and L. Chan. 2012. GLP-2 receptor in POMC neurons suppresses feeding behavior and gastric motility. Am J Physiol Endocrinol Metab. 303: E853-64. Epub 2012 Jul 24. (** denotes the corresponding author). Article selected as Editor’s Highlight in this issue.
4. Wang, Y., X. Shi, J. Qi, X. Li, K. Uray, and X. GUAN**. 2012. SIRT1 inhibits the mouse intestinal motility and epithelial proliferation. Am J Physiol - Gastrointest Liver Physiol. 302(2):G207-17. (** denotes the corresponding author). Article selected as the cover of this issue.
5. Shi, X., X. Li, Y. Wang, K. Zhang, F. Zhou, L. Chan, D. Li, and X. GUAN**. 2011. Glucagon-like peptide-2 (GLP-2) stimulated protein synthesis through the PI3-kinase-dependent Akt-mTOR signaling pathway. Am J Physiol Endocrinol Metab. 300: E554-63. Epub 2010 Dec 21. (** denotes the corresponding author).
6. Wang, Y., X. Li, Y. Guo, L. Chan, and X. GUAN**. 2010. Alpha-lipoic acid increases energy expenditure by enhancing AMPK-PGC-1α signalling in the skeletal muscle of aged mice. Metabolism. 59:967-976. (** denotes the corresponding author).
7. Y. Wang and X. GUAN**. 2010. GLP-2 potentiates L-type Ca2+ channel activity associated with stimulated glucose uptake in hippocampal neurons. Am J Physiol Endocrinol Metab. 298: E156–166. Article selected as the cover of this issue. (** denotes the corresponding author).
8. GUAN**, X., Y. Wang, J. Qi, X. Shi, X. Li, K. Uray, Y. Guo, D. Li, B. Xia, and D. Burrin. 2010. Sirt1 regulates the mouse gastric emptying and intestinal growth. Gastroenterology. 138: S402. (** denotes the corresponding author).
9. Burrin, D. G., B. Stoll, X. GUAN, L. Cui, X. Chang, and D. L. Hadsell. 2007. GLP-2 rapidly activates divergent intracellular signaling pathways involved in intestinal cell survival and proliferation in neonatal piglets. Am. J. Physiol. Endocrinol. Metab. 292(1):E281-91.
10. GUAN, X., H. E. Karpen, J. Stephens, J. T. Bukowski, S. Niu, G. Zhang, B. Stoll, M. J. Finegold, J. J. Holst, D. L. Hadsell, B. L. Nichols, and D. G. Burrin. 2006. GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow. Gastroenterology. 130: 150-164.
11. Burrin, D. G., B. Stoll, X. GUAN, L. Cui, X. Chang, and J. J. Holst. 2005. GLP-2 dose-dependently activates intestinal cell survival and proliferation in neonatal piglets. Endocrinology. 146: 22-32.
12. Bos, C., B. Stoll, H. Fouillet, C. Gaudichon, X. GUAN, M. A., Grusak, P. J. Reeds, D. Tome, and D. G. Burrin. 2005. Postprandial intestinal and whole-body nitrogen kinetics and distribution in piglets fed a single. Am. J. Physiol. Endocrinol. Metab. 288: E436-46.
13. GUAN**, X., B. J. Bequette, P. K. Ku, R. J. Tempelman, and N. L. Trottier. 2004. The amino acid need for milk synthesis is defined by the maximal uptake of plasma amino acids by porcine mammary glands. J. Nutr. 134: 2182-2190. (** denotes the corresponding author).
14. GUAN, X., B. Stoll, X. Lu, K. Tappenden, J. J. Holst, B. Hartman, and D. Burrin. 2003. GLP-2-mediated upregulation of intestinal blood flow and glucose uptake is nitric-oxide-dependent in TPN-fed piglets. Gastroenterology. 125: 136-147.
15. GUAN, X. F., B. J. Bequette, G. Calder, P. K. Ku, K. N. Ames, and N. L. Trottier. 2002. Amino acid availability affects amino acid flux and protein metabolism in the porcine mammary gland. J. Nutr. 132:1224-1234.

Books and chapters:

1. GUAN, X. F. and D. G. Burrin. 2005. “Methodological Approaches to Metabolism Research”. In: Biology of Metabolism in Growing Animals (Eds. DG. Burrin and HJ. Mersmann), London (United Kingdom): Elsevier Science B. V. Publishers, pp. 435-477.