Research Interest

• Understanding the molecular mechanisms, with a primary focus on microRNAs, that mediate the onset and progression of excess aldosterone-mediated cardio-renal injury.
• Primary aldosteronism accounts for ~10% of hypertensive patients.
• Excess aldosterone, inappropriate for the salt intake status, causes hypertension and cardio-renal fibrosis and inflammation.
• The molecular mechanisms that mediate excess aldosterone cardio-renal injury are poorly understood and are the main focus of his research.

Research Interests Keywords:

Aldosterone, Mineralocorticoids; Mineralocorticoid Receptor, Gene Expression, Mirnas, Animal Models, Microarrays, Renin-Angiotensin System, Steroid Hormones, Nuclear Receptors, Hypertension, Intracellular Signaling