Publications

  1. Syed M, Ball JP, Mathis KW, Hall ME, Ryan MJ, Rothenberg ME, Yanes Cardozo LL, Romero DG*. MicroRNA-21 Ablation Exacerbates Aldosterone-Mediated Cardiac Injury, Remodeling and Dysfunction. Am J Physiol Endocrinol Metab. 2018 315(6): E1154-E1167.
  2. Torres Fernandez ED, Adams KV, Maranon RO, Romero DG, Yanes Cardozo LL. Long-Lasting Androgen-Induced Cardiometabolic Effects in Polycystic Ovary Syndrome. J Endocr Soc. 2018 2(8): 949-964.
  3. Rajkowska G, Legutko B, Moulana M, Syed M, Romero DG, Miguel-Hidalgo JJ. Astrocyte Pathology in the Ventral Prefrontal White Matter in Depression. J Psychiatr Res. 2018 102:150-158.
  4. Gabrielli M, Romero DG, Martini CN, Raiger Iustman LJ, Vila MDC. MCAM knockdown impairs PPARγ expression and 3T3-L1 fibroblasts differentiation to adipocytes. Mol Cell Biochem. 2018 448(1-2): 299-309.
  5. Mahajan GJ, Vallender EJ, Garrett MR, Challagundla L, Overholser JC, Jurjus G, Dieter L, Syed M, Romero DG, Benghuzzi H, Stockmeier CA. Altered neuro-inflammatory gene expression in hippocampus in major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2018 82: 177-186.
  6. Dalmasso C, Patil CN, Yanes Cardozo LL, Romero DG, Maranon RO. Cardiovascular and metabolic consequences of testosterone supplements in young and old male SHR: Implications for testosterone supplements in men. J Am Heart Assoc. 2017 6(10) pii: e007074.
  7. Miguel-Hidalgo JJ, Hall KO, Roller AM, Bonner H, Syed M, Ball JP, Rothenberg ME, Stockmeier CA, Romero DG. MicroRNA-21: expression in oligodendrocytes and correlation with low myelin mRNAs in depression and alcoholism. Prog Neuropsychopharmacol Biol Psychiatry. 2017 79(Pt B): 503-514.
  8. Ball JP, Syed M, Marañon RO, Hall ME, KC R, Reckelhoff JF, Yanes Cardozo LL, Romero DG*. Role and regulation of microRNAs in aldosterone-mediated cardiac injury and dysfunction in male rats. Endocrinology 2017 158(6): 1859-1874.
  9. Do Carmo JM, da Silva AA, Romero DG, Hall JE. Changes in ambient temperature elicit divergent control of metabolic and cardiovascular actions by leptin. FASEB J. 2017 31(6): 2418-2428.
  10. Dalmasso C, Maranon RO, Patil CN, Moulana M, Romero DG, Reckelhoff JF. 20-HETE and CYP4A2 ω-hydroxylase contribute to the elevated blood pressure in hyperandrogenemic female rats. Am J Physiol Renal Physiol. 2016 311(1): F71-7.
  11. Yun J, Espinoza I, Pannuti A, Romero DG, Martinez L, Caskey M, Stanculescu A, Bocchetta M, Rizzo P, Band V, et al. p53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating with the Notch Transcriptional Complex via MAML1. J. Cell. Physiol. 2015 230(12): 3115-27.
  12. Kollareddy M, Dimitrova E, Chan A, Le T, Carrero ZI, Chauhan K, Ramakrishnan G, Watabe K, Boss GR, Romero DG, Radu CG, Martinez LA. Regulation of Nucleotide Metabolism by Mutant p53 Contributes to its Gain-of-Function Activities. Nat. Commun. 2015 6: 7389.
  13. Zhang MZ, Ferrigno O, Wang Z, Ohnishi M, Prunier C, Levy L, Razzaque M, Horne WC, Romero D, Tzivion G, Colland F, Baron R, Atfi A. TGIF Governs a Feed-Forward Network that Empowers Wnt Signaling to Drive Mammary Tumorigenesis. Cancer Cell. 2015 27(4): 547-60.
  14. Gabrielli M, Martini CN, Brandani JN, Iustman LJ, Romero DG, Vila MD. Exchange protein activated by cyclic AMP is involved in the regulation of adipogenic genes during 3T3-L1 fibroblasts differentiation. Dev Growth Differ. 2014 56(2): 143-151.
  15. Ettahar A, Ferrigno O, Zhang MZ, Ohnishi M, Ferrand N, Prunier C, Levy L, Bourgeade MF, Bieche I, Romero DG, Colland F, Atfi A. Identification of PHRF1 as a Tumor Suppressor that Promotes the TGF-β Cytostatic Program through Selective Release of TGIF- Driven PML Inactivation. Cell Rep. 2013 4(3): 530-41.
  16. Marañon RO, Juncos LA, Turoni CJ, Karbiner S, Romero DG, Peral de Bruno M. Tempol Blunts Afferent Arteriolar Remodeling In Chronic Nitric Oxide-Deficient Hypertension Without Normalizing Blood Pressure.Clin Exp Hypertens. 2014; 36(3): 132-9.
  17. Zgheib C, Kurdi M, Zouein FA, Gunter BW, Stanley BA, Zgheib J,Romero DG, King SB, Paolocci N, Booz GW. Acyloxy Nitroso Compounds Inhibit LIF Signaling in Endothelial Cells and Cardiac Myocytes: Evidence That STAT3 Signaling Is Redox-Sensitive. PLoS One. 2012;7(8): e43313.
  18. Yanes LL, Romero DG, Moulana M, Lima R, Davis DD, Zhang H, Lockhart R, Racusen LC, Reckelhoff JF. Cardiovascular-Renal and Metabolic Characterization of a Rat Model of Polycystic Ovary Syndrome. Gend Med. 2011 8(2): 103-15.
  19. Yanes LL,Romero DG, Iliescu R, Reckelhoff JF. A Single Pill to Treat Postmenopausal Hypertension? Not Yet. Curr Top Med Chem. 2011 11(3): 1736-1741.
  20. Yanes LL, Lima R, Moulana M, Romero DG, Yuan K, Ryan MJ, Baker R, Zhang H, Fan F, Davis DD, Roman RJ, Reckelhoff JF. Postmenopausal hypertension: Role of 20-HETE. Am J Physiol Regul Integr Comp Physiol. 2011 300(6): R1543-8.
  21. Romero DG, Gomez-Sanchez EP, Gomez-Sanchez CE. Angiotensin II- Regulated Transcription Regulatory Genes in Adrenal Steroidogenesis. Physiol Genomics. 2010 42A: 259-66.
  22. Yanes LL, Romero DG, Iliescu R, Zhang H, Davis D, Reckelhoff JF. Postmenopausal hypertension: role of the Renin-Angiotensin system.Hypertension. 2010 56(3): 359-63.
  23. Sartori-Valinotti JC, Venegas-Pont MR, Lamarca BB, Romero DG, Yanes LL, Racusen LC, Jones AV, Ryan MJ, Reckelhoff JF. Rosiglitazone reduces blood pressure in female Dahl salt-sensitive rats.Steroids. 2010 75(11): 794-9.
  24. Yanes LL, Romero DG. Dihydrotestosterone stimulates aldosterone secretion by H295R human adrenocortical cells. Mol Cell Endocrinol. 2009 303(1-2): 50-56.
  25. Gomez-Sanchez EP, Gomez-Sanchez MT, de Rodriguez AF, Romero DG, Warden MP, Plonczynski MW, Gomez-Sanchez CE. Immunohistochemical demonstration of the mineralocorticoid receptor, 11beta-hydroxysteroid dehydrogenase-1 and -2, and hexose-6- phosphate dehydrogenase in rat ovary. J Histochem Cytochem. 2009 57(7): 633-41.
  26. Yanes LL, Sartori-Valinotti JC, Iliescu R, Romero DG, Racusen LC, Zhang H, Reckelhoff JF. Testosterone dependent hypertension and upregulation of intrarenal angiotensinogen in Dahl salt sensitive rats.Am J Physiol Renal Physiol. 2009 296(4): F771-9.
  27. Shah P, Romero DG, Swiatlo E. Role of polyamine transport in Streptococcus pneumoniae response to physiological stress and murine septicemia. Microb Pathog. 2008 45(3): 167-72.
  28. Romero DG, Plonczynski MW, Carvajal CA, Gomez-Sanchez EP and Gomez-Sanchez CE. MicroRNA-21 increases aldosterone secretion and proliferation in H295R human adrenocortical cells. Endocrinology. 2008 149(5): 2477-83.
  29. Kubisch HM, Gagliardi C, Romero DG, Bunnell BA, Ratterree MS. Kinetics of pronuclear development and the effects of vector type and timing of injection on the efficiency of gene transfer into rhesus macaque embryos. Mol Reprod Dev. 2008 75(10): 1505-14.
  30. Gomez-Sanchez EP, Romero DG, de Rodriguez AF, Warden MP, Krozowski Z, Gomez- Sanchez CE. Hexose-6-phosphate dehydrogenase and 11 beta-hydroxysteroid dehydrogenase-1 tissue distribution in the rat. Endocrinology. 2008 149(2): 525-33.
  31. Romero DG, Plonczynski MW, Welsh BL, Gomez-Sanchez CE, Zhou MY, Gomez-Sanchez EP. Gene expression profile in rat adrenal zona glomerulosa cells stimulated with aldosterone secretagogues. Physiol Genomics. 2007 32(1): 117-27.
  32. Romero DG, Zhou MY, Yanes LL, Plonczynski MW, Washington TR, Gomez-Sanchez CE, Gomez- Sanchez EP. RGS4 in adrenal gland: localization, regulation and role in aldosterone secretion. J Endocrinology. 2007 194(2): 429-40.
  33. Romero DG, Rilli S, Plonczynski MW, Yanes LL, Zhou MY, Gomez-Sanchez EP, Gomez- Sanchez CE. Adrenal transcription regulatory genes modulated by angiotensin II and their role in steroidogenesis. Physiol Genomics. 2007 30(1): 26-34.
  34. Martini CN, Romero DG, Yanes LL, Vila Mdel C. Induction of 5-aminolevulinate synthase by activators of steroid biosynthesis. Life Sci. 2007 81(1): 19-25.
  35. Romero DG, Yanes LL, de Rodriguez AF, Plonczynski MW, Welsh BL, Reckelhoff JF, Gomez-Sanchez EP, Gomez-Sanchez CE. Disabled-2 is expressed in adrenal zona glomerulosa and is involved in aldosterone secretion. Endocrinology. 2007 148(6): 2644-52.
  36. Romero DG, Welsh BL, Gomez-Sanchez EP, Yanes LL, Rilli S, Gomez-Sanchez CE. Angiotensin II-mediated protein kinase D activation stimulates aldosterone and cortisol secretion in H295R human adrenocortical cells. Endocrinology. 2006 147(12): 6046-55.
  37. Yanes LL, Romero DG, Iles JW, Iliescu R, Gomez-Sanchez C, Reckelhoff JF. Sexual dimorphism in the renin-angiotensin system in aging spontaneously hypertensive rats. Am J Physiol Regul Integr Comp Physiol. 2006 291(2): R383-90.
  38. Romero DG, Plonczynski MW, Gomez-Sanchez EP, Yanes LL, Gomez-Sanchez CE. RGS2 is regulated by angiotensin II and functions as a negative feedback of aldosterone production in H295R human adrenocortical cells. Endocrinology. 2006 147(8): 3889-97.
  39. Gomez-Sanchez CE, de Rodriguez AF, Romero DG, Estess J, Warden MP, Gomez-Sanchez MT, Gomez-Sanchez EP. Development of a panel of monoclonal antibodies against the mineralocorticoid receptor. Endocrinology. 2006 147(3): 1343-8.
  40. Romero DG, Vergara GR, Zhu Z, Covington GS, Plonczynski MW, Yanes LL, Gomez- Sanchez EP, Gomez-Sanchez CE. Interleukin-8 synthesis, regulation, and steroidogenic role in H295R human adrenocortical cells. Endocrinology. 2006 147(2): 891-8.
  41. Yanes LL, Romero DG, Iliescu R, Cucchiarelli VE, Fortepiani LA, Santacruz F, Bell W, Zhang H, Reckelhoff JF. Systemic arterial pressure response to two weeks of Tempol therapy in SHR:involvement of NO, the RAS, and oxidative stress. Am J Physiol Regul Integr Comp Physiol. 2005 288(4): R903-8.
  42. Gomez-Sanchez EP, Ahmad N, Romero DG, Gomez-Sanchez CE. Is aldosterone synthesized within the rat brain? Am J Physiol Endocrinol Metab. 2005 288(2): E342-6.
  43. Yanes LL, Romero DG, Cucchiarelli VE, Fortepiani LA, Gomez-Sanchez CE, Santacruz F, Reckelhoff JF. Role of endothelin in mediating postmenopausal hypertension in a rat model. Am J Physiol Regul Integr Comp Physiol. 2005 288(1): R229-33.
  44. Carvajal CA, Romero DG, Mosso LM, Gonzalez AA, Campino C, Montero J, Fardella CE. Biochemical and genetic characterization of 11 beta-hydroxysteroid dehydrogenase type 2 in low-renin essential hypertensives. J Hypertens. 2005 23(1): 71-7.
  45. Gomez-Sanchez EP, Ahmad N, Romero DG, Gomez-Sanchez CE. Origin of aldosterone in the rat heart. Endocrinology. 2004 145(11): 4796-802.
  46. Romero DG, Plonczynski M, Vergara GR, Gomez-Sanchez EP, Gomez-Sanchez CE. Angiotensin II early regulated genes in H295R human adrenocortical cells. Physiol Genomics. 2004 19(1): 106-16.
  47. Ahmad N, Romero DG, Gomez-Sanchez EP, Gomez-Sanchez CE. Do human vascular endothelial cells produce aldosterone? Endocrinology. 2004 145(8): 3626-9.
  48. Gomez-Sanchez EP, Ganjam V, Chen YJ, Liu Y, Zhou MY, Toroslu C, Romero DG, Hughson MD, de Rodriguez A, Gomez-Sanchez CE. Regulation of 11 beta-hydroxysteroid dehydrogenase enzymes in the rat kidney by estradiol. Am J Physiol Endocrinol Metab. 2003 285(2): E272-9.
  49. Carvajal CA, Gonzalez AA, Romero DG, Gonzalez A, Mosso LM, Lagos ET, Hevia Mdel P, Rosati MP, Perez-Acle TO, Gomez-Sanchez CE, Montero JA, Fardella CE. Two homozygous mutations in the 11 beta-hydroxysteroid dehydrogenase type 2 gene in a case of apparent mineralocorticoid excess.J Clin Endocrinol Metab. 2003 88(6): 2501-7.
  50. Yu L, Romero DG, Gomez-Sanchez CE, Gomez-Sanchez EP. Steroidogenic enzyme gene expression in the human brain. Mol Cell Endocrinol. 2002 190(1-2): 9-17.
  51. Romero DG, Zhou M, Gomez-Sanchez CE. Cloning and expression of the bovine 11beta- hydroxysteroid dehydrogenase type-2. J Steroid Biochem Mol Biol. 2000 72(5): 231-7.
  52. Pecci A, Romero DG, Lantos CP, Cozza EN. Mechanisms of action of endothelin-1 in rat adrenal. Life Sci. 1998 63(15): 1315-28.
  53. Morita H, Cozza EN, Zhou MY, Gomez-Sanchez EP, Romero DG, Gomez-Sanchez CE. Regulation of the 11 beta-hydroxysteroid dehydrogenase in the rat adrenal. Decrease enzymatic activity induced by ACTH. Endocrine. 1997 7(3): 331-5.
  54. Martini CN, Vaena de Avalos SG,Romero DG, San Martin de Viale L, Vila Mde C. Heme availability affects corticosterone and aldosterone biosynthesis in rat adrenal. Steroids. 1997 62(12): 767-70.
  55. Pecci A, Romero DG, Gomez-Sanchez CE, Lantos CP, Cozza EN. Effects of staurosporine on ACTH-mediated stimulation of aldosterone production. Cell Signal. 1996 8(5): 381-6.
  56. Romero DG, Pecci A, Lantos CP, Cozza EN. Endothelin-1-induced incorporation of cholesterol into rat adrenals. Steroids. 1996 61(5): 317-22.

 

Damian G. Romero

Associate Professor


:(601) 984-1523

  • DEPARTMENTDepartment of Biochemistry
    University of Mississippi Medical Center
  • COUNTRYUSA