Peer-Reviewed Journal Publications

  1. Wilkinson, S. M.; Gunosewoyo, H.; Barron, M. L.; Boucher, A.; McDonnell, M.; Turner, P.; Morrison, D. E.; Bennett, M. R.; McGregor, I. S.; Rendina, L. M.; Kassiou, M. (2014) The First CNS-Active Carborane: A Novel P2X7 Receptor Antagonist with Antidepressant Activity. ACS Chem. Neurosci. 5 (5): 335-339.
  2. Pal, K.; Cao, Y.; Gaisina, I. N.; Bhattacharya, S.; Dutta, S. K.; Wang, E.; Gunosewoyo, H.; Kozikowski, A.; Billadeau, D. D.; Mukhopadhyay, D. (2014) Inhibition of GSK-3 Induces Differentiation and Impaired Glucose Metabolism in Renal Cancer. Mol. Cancer Ther. 13 (2): 285-296.
  3. Lun, S.; Guo, H.; Onajole, O. K.; Pieroni, M.; Gunosewoyo, H.; Chen, G.; Tipparaju, S. K.; Ammerman, N. C.; Kozikowski, A. P.; Bishai, W. R. (2013) Indoleamides are Active Against Drug-Resistant Mycobacterium tuberculosis. Nature Comm. 4: 2907.
  4. Gunosewoyo, H.; Midzak, A.; Gaisina, I. N.; Sabath, E.; Fedolak, A.; Hanania, T.; Brunner, D.; Papadopoulos, V.; Kozikowski, A. P. (2013) Characterization of Maleimide-Based Glycogen Synthase Kinase-3 (GSK-3) Inhibitors as Stimulators of Steroidogenesis. J. Med. Chem. 56 (12): 5115-5129.
  5. Onajole, O. K.; Pieroni, M.; Tipparaju, S. K.; Lun, S.; Stec, J.; Chen, G.; Gunosewoyo, H.; Guo, H.; Ammerman, N. C.; Bishai, W. R.; Kozikowski, A. P. (2013) Preliminary Structure–Activity Relationships and Biological Evaluation of Novel Antitubercular Indolecarboxamide Derivatives Against Drug-Susceptible and Drug-Resistant M. tuberculosis Strains. J. Med. Chem. 56 (10): 4093-4103.
  6. Gunosewoyo, H.; Tipparaju, S.K.; Pieroni, M.; Wang, Y.; Doctor, B.P.; Nambiar, M.P.; Kozikowski, A.P. (2013) Structural Analogs of Huperzine A Elicit Neuroprotective Effects and Improve Survival in Guinea Pigs Exposed to Soman. Bioorg. Med. Chem. Lett. 23 (5): 1544-1547.
  7. Yu, L.-F.; Zhang, H.-K.; Gunosewoyo,  H.; Kozikowski, A. P. (2012) From α4β2 Nicotinic Ligands to the Discovery of σ1 Receptor Ligands: Pharmacophore Analysis and Rational Design. ACS Med. Chem. Lett. 3 (12): 1054-1058.
  8. Kozikowski, A. P.; Gunosewoyo, H.; Guo, S.; Gaisina, I. N.; Walter, R. L.; Ketcherside, A.; McClung, C. A.; Mesecar, A. D.; Caldarone, B. (2011) Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice. ChemMedChem 6 (9): 1593–1602.
  9. Chen, W.; Gaisina, I. N.; Gunosewoyo, H.; Malekiani, S. A.; Hanania, T.; Kozikowski, A. P. (2011) Structure-Guided Design of a Highly Selective Glycogen Synthase Kinase-3beta Inhibitor: a Superior Neuroprotective Pyrazolone Showing Antimania Effects. ChemMedChem 6 (9): 1587–1592.
  10. Gunosewoyo, H.; Kassiou, M. (2010) P2X Purinergic Receptor Ligands: Recently Patented Compounds. Expert Opin. Ther. Patents 20 (5): 625–646.
  11. Gunosewoyo, H.; Coster, M. J.; Bennett, M. R.; Kassiou, M. (2009) Purinergic P2X7  Receptor Antagonists: Chemistry and Fundamentals of Biological Screening. Bioorg. Med. Chem. 17 (14): 4861–4865.
  12. Gunosewoyo, H.; Guo, J. L.; Bennett, M. R.; Coster, M. J.; Kassiou, M. (2008) Cubyl Amides: Novel P2X7 Receptor Antagonists. Bioorg. Med. Chem. Lett. 18 (13): 3720–3723.
  13. Gunosewoyo, H.; Coster, M. J.; Kassiou, M. (2007) Molecular Probes for P2X7  Receptor Studies. Curr. Med. Chem. 14: 1505–1523.


Hendra Gunosewoyo

Assistant Professor


  • DEPARTMENTDepartment of health sciences
    Curtin University
  • COUNTRYAustralia