Publications

Publications (selected from more than 50 publications)

1. Voll EA, Ogden IM, Pavese JM, Huang X, Xu L, Jovanovic BD, and Bergan RC.Heat shock protein 27 regulates human prostate cancer cell motility and metastatic progression.    Oncotarget.    2014, 5(9): 2648-2663 PMID: 24798191      
2. Krishna SN, Luan CH, Mishra RK, Xu L, Scheidt KA, Anderson WF, Bergan RC.  A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated protein kinase kinase 4.   PLoS One.  2013, 8(12): pe81504 PMID: 24339940      
3. Pavese JM, Ogden IM, Voll EA, Huang X, Xu L, Jovanovic B, Bergan RC. Mitogen-activated protein kinase kinase 4 (MAP2K4) promotes human prostate cancer metastasis.  PLoS One.  2014, 9(7):e102289. PMID: 25019290      
4. Li T, Wang H, Sun Y, Zhao L, Gang Y, Guo X, Huang R, Yang Z, Pan Y, Wu K, Xu L, Liu Z, and Fan D.  Transcription Factor CUTL1 Is a Negative Regulator of Drug Resistance in Gastric Cancer. The Journal of biological chemistry.  2013, 288: 4135-4147  PMID: 23255599        (corresponding author)
5. Xiao X, Gang Y, Gu Y, Zhao L, Chu J, Zhou J, Cai X, Zhang H, Xu L, Nie Y, Wu K, Liu Z, and Fan D.Osteopontin contributes to TGF-beta1 mediated hepatic stellate cell activation. Digestive diseases and sciences.  2012,57:2883-2891
6. Xu L, Wang SS, Healey MA, Faupel-Badger JM, Wilken JA, Battaglia T, Szabo E, Mao JT, Bergan RC. The Ninth Annual American Association of cancer research international conference on frontiers in cancer prevention research.  Cancer Prev Res (Phila).  2011 Apr;4(4):616-21 PMID: 21464034
7. Farmer RL, Biddle MM, Nibbs AE, Huang XK, Xu L, Bergan RC and Scheidt, KA.  Concise syntheses of the abyssinones and discovery of new inhibitors of prostate cancer and MMP-2 expression. ACS Med Chem Lett.  2010 Nov 11;1(8):400-405     PMID: 21116437, PMCID: PMC2992379     
8. Xu L, Ding Y, Catalona WJ, Yang XJ, Anderson WF, Jovanovic B, Wellman K, Kilmer J, Huang X, Scheidt KA, Montgomery RB and Bergan RC. MEK4 function, genistein treatment, and invasion of human prostate cancer cells. J Natl Cancer Inst. 2009, 101(16):1141-55.  PMID: 19638505, PMCID: PMC2728746
9. Lakshman M, Xu L, Ananthanarayanan V, Cooper J, Takimoto CH, Helenowski I and Bergan RC. Dietary genistein inhibits metastasis of human prostate cancer in mice.  Cancer Research.  2008, 68(6):2024-32.  PMID: 18339885
10. Craft CS, Xu L, Romero D, Vary CP and Bergan RC. Genistein induces phenotypic reversion of endoglin deficiency in human prostate cancer cells.  Molecular Pharmacology.  2008, 73(1):235-242.   PMID: 17951357
11. Ding Y, Xu L, Jovanovic BD, Helnowski IB, Kelly DL, Catalona WJ, Yang XJ, Pins M and Bergan RC.    The methodology used to measure differential gene expression affects the outcome. Journal of Biomolecular Techniques. 2007, 18(5):321-330. PMID: 18166675
12. Xu L and Bergan RC.Genistein inhibits MMP-2 activation and prostate cancer cell invasion by blocking TGFb-mediated activation of the MAPKAPK2-HSP27 pathway.  Molecular Pharmacology.  2006, 70(3):869-877. PMID: 16772519      
13. Xu L, Chen S and Bergan RC. MAPKAPK2 and HSP27 are downstream mediators of TGFb-dependent cell invasion in human prostate cancer. Oncogene.  2006, 25(21): 2987-2998. PMID: 16407830      
14. Ding Y, Xu L, Chen S, Jovanovic BD, Helnowski IB, Kelly DL, Catalona WJ, Yang XJ, Pins M, Ananthanarayanan V and Bergan RC. Characterization of a method for profiling gene expression in cells recovered from intact human prostate tissue using RNA linear amplification. Prostate Cancer and Prostatic Diseases.  2006, 9(4):379-391.    PMID: 16786039, PMCID: PMC2392989 
15. Huang X, Chen S, Xu L, Liu Y, Deb DK, Platanias LC and Bergan RC. Genistein inhibits p38 MAP kinase activation, MMP-2, and cell invasion in human prostate. Cancer Research.  2005, 65(8):3470-3478.     PMID: 15833883      
16. Xu L, Jin BQ and Fan DM. Selection and identification of mimic epitopes for gastric cancer-associated antigen MG7 Ag.                 Molecular Cancer Therapeutic.  2003, 2(3):301-306. PMID: 12657725