Publications

1. Wang, L. X., G. Kang, P. Kumar, W. Lu, Y. Li, Y. Zhou, Q. Li, and C. Wood. Humanized-BLT mouse  model of Kaposi's sarcoma-associated herpesvirus infection. Proc Natl Acad Sci U S A, 2014, 111:3146-51.  PMCID: PMC3939909   (Corresponding author). 
2. Wang, N., Y. Li, W. Niu, M. Sun, R. Cerny, Q. Li, and J. Guo. Construction of a Live-Attenuated HIV-1 Vaccine through Genetic Code Expansion. Angewandte  Chemie International. 2014, 5;53 (19):4867-71. PMID: 24715496 (Nat Chem commented this paper: Virus engineering: Fighting HIV at its own game. Nat Chem 2014 6:566-568)(Corresponding author).
3. Wang, Z., A. Zhang, Y. Wan, X. Liu, C. Qiu, X. Xi, Y. Ren, J. Wang, Y. Dong, M. Bao, L. Li, M. Zhou, S. Yuan, J. Sun, Z. Zhu, L. Chen, Q. Li, Z. Zhang, X. Zhang, S. Lu, P. C. Doherty, K. Kedzierska, and J. Xu. 2014. Early hypercytokinemia is associated with interferon-induced transmembrane protein-3 dysfunction and predictive of fatal H7N9 infection. Proc Natl Acad Sci U S A, 2014, 111:769-774.
4. Demers, A., G. Kang, F. Ma, W. Lu, Z. Yuan, Y. Li, M. Lewis, E. N. Kraiselburd, L. Montaner, and Q. Li.  The mucosal expression pattern of interferon-epsilon in rhesus macaques. J Leukoc Biol , 2014. 96:1101-1107. (Corresponding author). 
5. Lu W, F. Ma, A. Tchourbanov, Y.  Li, G. Kang,  Z. Yuan, D. Wang, C. Zhang, J. Xu, M. Lewis, Q. Li.    Virus–host mucosal interactions during early SIV rectal transmission. Virology, 2014, 464–465:406-414.  PMID: 25128762. (Corresponding author).
6. Li, Q., M. Zeng, L. Duan, J. E. Voss, A. J. Smith, S. Pambuccian, L. Shang, S. Wietgrefe, P. J. Southern, C. S. Reilly, P. J. Skinner, M. L. Zupancic, J. V. Carlis, M. Piatak, D. Waterman, R. K. Reeves, K. Masek-Hammerman, C. A. Derdeyn, M. D. Alpert, D. T. Evans, H. Kohler, S. Müller, J. Robinson, J. D. Lifson, D. R. Burton, R. P. Johnson, and A. T. Haase. Live Simian Immunodeficiency Virus Vaccine Correlate of Protection: Local Antibody Production and Concentration on the Path of Virus Entry. The Journal of Immunology. 2014, 193:3113-3125. (cover article)
7. Shaheed A., M. Martinez, G. Kang, A. Foulkes, I. V. Rodriguez,  S.M. Nichols, M. Hunter, C. Sariol, L.A. Ruiz, B. Ross, X. Yin, D. Speicher, A. Haase, P.A. Marx, Q. Li, E. K., and L.J. Montaner. Serial Cervicovaginal Exposures With Replication-Deficient SIVsm Induce Higher Dendritic Cell (pDC) and CD4+ T-Cell Infiltrates Not Associated With Prevention but a More Severe SIVmac251 Infection of Rhesus Macaques. J. AIDS. 2014, 65:405-413 410. PMID: 24226059.
8. Smith, A. J., S. W. Wietgrefe, L. Shang, C. S. Reilly, P. J. Southern, K. E. Perkey, L. Duan, H. Kohler, S. Müller, J. Robinson, J. V. Carlis, Q. Li, R. P. Johnson, and A. T. Haase. 2014. Live Simian Immunodeficiency Virus Vaccine Correlate of Protection: Immune Complex–Inhibitory Fc Receptor Interactions That Reduce Target Cell Availability. The Journal of Immunology. 2014 193:3126-3133.
9. Gibbs, A., T. Hirbod, Q. Li, K. Bohman, T. B. Ball, F. A. Plummer, R. Kaul, J. Kimani, K. Broliden, and A. Tjernlund. Presence of CD8+ T cells in the ectocervical mucosa correlates with genital viral shedding in HIV-infected women despite a low prevalence of HIV RNA-expressing cells in the tissue. J Immunol. 2014, 192:3947-3957.
10. Barrenas, F., R. E. Palermo, B. Agricola, M. B. Agy, L. Aicher, V. Carter, L. Flanary, R. R. Green, R. McLain, Q. Li, W. Lu, R. Murnane, X. Peng, M. J. Thomas, J. M. Weiss, D. M. Anderson, and M. G. Katze. Deep Transcriptional Sequencing of Mucosal Challenge Compartment from Rhesus Macaques Acutely Infected with Simian Immunodeficiency Virus Implicates Loss of Cell Adhesion Preceding Immune Activation. Journal of Virology, 2014 88:7962-7972.
11. Massilamany, C., A. Gangaplara, T. Jia, C. Elowsky, Q. Li, Y. Zhou, and J. Reddy. In situ detection of autoreactive CD4 T cells in brain and heart using major histocompatibility complex class II dextramers. J Vis Exp. 2014 1:51679.
12. Massilamany, C., A. Gangaplara, T. Jia, C. Elowsky, G. Kang, J. J. Riethoven, Q. Li, Y. Zhou, and J. Reddy. Direct staining with major histocompatibility complex class II dextramers permits detection of antigen-specific, autoreactive CD4 T cells in situ. PLoS ONE 2014, 9:e87519.
13. Reeves, R. K., G. Kang, H. Li, and Q. Li. Depletion of lamina propria innate lymphoid cells in simian immunodeficiency virus infection. AIDS Res Hum Retroviruses. 2014,30:1160-1161.
14. Luo, M., D. Tang, D. La, R. Capina, X.-Y. Yuan, J. Correia-Pinto, C. Prego, M. Alonso, C. Barry, R. Pilon, C. Daniuk, M. Nykoluk, S. Pillet, T. Bielawny, J. Tuff, C. Czarnecki, P. Lacap, G. Wong, S. Tyler, B. Liang, Z. Yuan, Q. Li, T. B. Ball, P. Sandstrom, G. Kobinger, and F. Plummer. Longitudinal Analysis of SIVmac239 Mutations around the 12 Protease Cleavage Sites and their Correlations with Viral Load Reduction and CD4 counts. AIDS Research and Human Retroviruses 2014, 30:A245-A246.
15. Tang, D., D. La, R. Capina, X.-Y. Yuan, J. Correia-Pinto, C. Prego, M. Alonso, C. Barry, R. Pilon, C. Daniuk, M. Nykoluk, S. Pillet, T. Bielawny, J. Tuff, C. Czarnecki, P. Lacap, G. Wong, S. Tyler, B. Liang, Z. Yuan, Q. Li, T. B. Ball, P. Sandstrom, G. Kobinger, F. Plummer, and M. Luo. Sequences Surrounding the 12 Protease Cleavage Sites are Good Targets for Both Prophylactic and Therapeutic HIV Vaccines. AIDS Research and Human Retroviruses. 2014, 30:A246-A246.
16. Patterson LJ, Kuate S, Daltabuit-Test M, Li Q, Xiao P, McKinnon K, Dipasquale J, Cristillo A, Venzon D, Haase A, Robert-Guroff M. Replicating Adenovirus-Simian Immunodeficiency Virus (SIV) Vectors Efficiently Prime SIV-Specific Systemic and Mucosal Immune Responses by Targeting Myeloid Dendritic Cells and Persisting in Rectal Macrophages, Regardless of Immunization Route.Clin Vaccine Immunol. 2012, 19(5):629-37. PMID:  22441384.
17. Reeves RK, TI Evans, J Gillis, FE Wong, G Kang, Q Li, and RP Johnson. SIV infection induces accumulation of plasmacytoid dendritic cells in the gut mucosa. J. Infect. Dis.  2012, 206(9):1462-8. PMID: 22711907.
18. Bokhari, S., R. Hegde, SM. Bokhari, R. Hegde, S. Callen, H. Yao, I. Adany, Q. Li, Z. Li, D. Pinson, H-W. Yeh,  P. Cheney, and S. Buch . Morphine Potentiates Neuropathogenesis of SIV Infection in Rhesus Macaques. Journal of Neuroimmune Pharmacology . 2011, 6(4): 626–639, PMID 21431470.
19. Li Q, Wood C. Challenges and counter challenges in HIV/AIDS.Chin Med J (Engl). 2010 Dec;123(23):3379-80. PMID:22166517 (Corresponding author).
20. Yukl, Steven A., S. Gianella, Sara, E. Sinclair, L. Epling, Q. Li, L. Duan,  AM. Choi, V. Girling, H. Terence, P. Li, K. Fujimoto, H. Lampiris, CB. Hare, M. Pandori,  AT. Haase, HF. Günthard, M. Fischer, AK. Shergill, K. McQuaid, Kenneth DV. Havlir, JK. Wong.  Differences in HIV Burden and Immune Activation within the Gut of HIV‐Positive Patients Receiving Suppressive Antiretroviral Therapy. J. Infect. Dis. 2010, 202(10): 1553-1561.PMID: 20939732.
21. García A, N.B. Siddappa, Q. Li, A.T. Haase, K. Paul, F. Stroud, X. Zhang, J. A. Fountain, F. Villinger, F. Novembre, J.G. Else, E. Secor and R.M. Ruprecht. AIDS and optic neuritis in a rhesus monkey infected with the R5 clade C SHIV-1157ipd3N4.  J Med Primatol. 2010 39(5)356-360, PMID-20412378.
22. Smith A. J., Q. Li, S.W. Wietgrefe, T. W. Schacker, C. S. Reilly, and A. T. Haase. Host Genes Associated with HIV-1 Replication in Lymphatic Tissue.  J. Immunol. 2010, 185(9)5417-5424. PMID: 20935203.
23. Li, Q., J.D. Estes, P.M. Schlievert, L. Duan, A.J. Brosnahan, P.J. Southern, C.S. Reilly, M.L. Peterson, N. Schultz-Darken, K.G. Brunner, K.R. Nephew, S. Pambuccian, J.D. Lifson, J.V. Carlis, and A.T. Haase.  Glycerol monolaurate prevents mucosal SIV transmission. Nature 2009 458: 1034-1038. PMCID: PMC2785041
24. Li, Q., P.J. Skinner, S.-J. Ha, L. Duan, T.L. Mattila, A. Hage, C. White, D.L. Barber, L. O’Mara, P.J. Southern, C.S. Reilly, J.V. Carlis, C.J. Miller, R. Ahmed, and A.T. Haase. Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection. Science 2009 323: 1726-1729. PMCID: PMC2753492
25. Bosinger, SE., Q. Li, SN. Gordon, NR. Klatt, L. Duan, L. Xu, N. Fancella, A. Sidahmed, AJ. Smith, EA. Cramer, M. Zeng, D. Masopust, JV. Carlis, L. Ran, TH. Vanderford, M. Paiardini, RB. Isett, DA. Baldwin, JG. Else, SI. Staprans, G. Silvestri, AT. Haase, D J. Kelvin. Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys. J. Clin. Invest. 2009, 119:3556–3572. PMID:19959874. (Li Q. is a co-first-authorship with equal contribution).
26. Li, Q., A.J. Smith, T.W. Schacker, J.V. Carlis, L. Duan, C.S. Reilly, and A.T. Haase. Microarray analysis of lymphatic tissue reveals stage-specific, gene-expression signatures in HIV-1 infection. J. Immunol. 2009, 183: 1975–1982. PMID: 19596987.
27. Li Q, J. Skinner P, Duan L, Haase AT. A technique to simultaneously visualize virus-specific CD8+ T Cells and Virus-Infected Cells In situ. J. Vis. Exp. 2009 Aug 13;(30) PMID: 19684569.
28. Li, Q., J.D. Estes, L. Duan, J. Jessurun, S. Pambuccian, C. Forster, S. Wietgrefe, M. Zupancic, T. Schacker, C. Reilly, J.V. Carlis, and A.T. Haase. Simian immunodeficiency virus-induced intestinal cell apoptosis is the underlying mechanism of the regenerative enteropathy of early infection. J. Infect. Dis. 2008, 197:420-429. PMID:18199035.
29. Weiler, A.M., Q. Li, L. Duan, M. Kaizu, K.L. Weisgrau, T.C. Friedrich, M.R. Reynolds, A.T. Haase, and E.G. Rakasz. 2008. Genital ulcers facilitate rapid viral entry and dissemination following intravaginal inoculation with cell-associated simian immunodeficiency virus SIVmac239. J. Virol. 2008 82: 4154-4158. PMID: 18272571.
30. Estes, J.D., Q. Li, M.R. Reynolds, L. Duan, T. Schacker, S. Wietgrefe, LJ. Picker, D.I. Watkins, J.D. Lifson, C. Reilly, J. Carlis, and A.T. Haase. Premature induction of an immunosuppressive T regulatory response in acute SIV infection. J. Infect. Dis. 2006, 193:703-712.PMID: 16453267.
31. Miller, C.J., Q. Li, K. Abel, E.-Y. Kim, Z.-M. Ma, S. Wietgrefe, L. LaFranco-Scheuch, L. Compton, L. Duan, M. D. Shore, M. Zupancic, M. Busch, J. Carlis, S. Wolinsky, and A.T. Haase. Propagation and dissemination of infection after vaginal transmission of SIV. J. Virol. 2005 79: 9217-9227PMID: 15994816.
32. Li, Q., J.D. Lifson, L. Duan, T.W. Schacker, C. Reilly, J.V. Carlis, J.D. Estes, and A.T. Haase. Potential roles for follicular dendritic cell associated osteopontin in lymphoid follicle pathology and repair and B cell regulation in HIV-1 and SIV infections. J. Infect. Dis. 2005, 192:1269-1276. . PMID: 15994816.
33. Li, Q., L. Duan, J.D. Estes, Z.-M. Ma, T. Rourke, Y. Wang, C. Reilly, J. Carlis, C.J. Miller, and A.T. Haase.  Peak SIV replication in “resting” memory CD4+ T cells depletes gut lamina propria CD4+ T cells. Nature 2005,  434(7037):1148-52, PMID: 15793562.
34. Zhang, Z.-Q., S.W. Wietgrefe, Q. Li, M.D. Shore, L. Duan, C. Reilly, J.D. Lifson and A.T. Haase. Roles of substrate availability and infection of resting and activated CD4+ T cells in transmission and acute simian immunodeficiency virus infection. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:5640-5645. PMID: 15064398.
35. Li, Q., K.G. Mansfield, A.A. Lackner, and A.T. Haase. Quantitative image analysis of simian immunodeficiency virus replication in macrophages co-infected with Mycobacterium avium complex. J. Infect. Dis. 2000, 181:867-871. PMID:10720506.
36. Li Q, Eiden LE, Cavert W, Reinhart TA, Rausch DM, Murray EA, Weihe E, Haase AT. Increased expression of nitric oxide synthase and dendritic injury in simian immunodeficiency virus encephalitis.J Hum Virol. 1999, 2(3):139-45. PMID:10413365.
37. Li, Q., K. Gebhard, T. Schacker, K. Henry, and A.T. Haase. The relationship between tumor necrosis factor and human immunodeficiency virus gene expression in lymphoid tissue. J. Virol. 1997 71:7080-7082. PMID: 9261439.

Book chapters

1. Li Q.   (2014). T cell based HIV-1 vaccine in the era of broadly neutralizing antibody (in Chinese). In Wang YC (Ed.) HIV Vaccine Development and Evaluation. .
2. Li Q and C. Wood.(2014). Humanized-mouse versus non-human primate models of HIV-1 infection, In Poluektova LY, Cracia-Martinez JV., Koyanagi Y,  Manz MG. and Tager AM (Ed.). Humanized Mice for HIV Research. Springer..
3. Li Q.   (2014). Collagen Deposition and Fibrosis in the Lymphatic Tissues of HIV-1, in   Thomas Hope, Douglas D. Richman, Mario Stevenson [Eds.]Encyclopedia of AIDS Encyclopedia of AIDS.Springer.