Publications

Peer Reviewed Publications:

Note—

  • Papers below cumulatively cited over 3000 times.
  • h-index =18
  • i10-index =22
  • Most significant Authors are listed first and last, and then in order from left to right.
  1. Merriman PJ, Grimes CD, Ambroziak J, Hackett DA, Skinner PJ, Simmons MJ.  S Elements: A Family of Tcl-Like Transposons in the Genome of Drosophila melanogaster.  Genetics 1995; 141: 1425-1438. Impact factor 4, cited 41 times. 
  2. Shepard DA, Ehnstrom JG, Skinner PJ, and Schiff LA. Mutations in the Zinc-Binding Motif of the Reovirus Capsid Protein Sigma 3 Eliminate its ability to Associate With Capsid Protein Mu 1.  Journal of Virology 1996; 70(3): 2065-2068.   Impact Factor 5.3, cited 29 times.  
  3. Schmechel S, Chute M, Skinner P, Anderson R, and Schiff L. Preferential Translation of Reovirus mRNA by a Sigma3-Dependent Mechanism.  Virology 1997; 232: 62-73. Impact Factor 3.8, cited 44 times.
  4. Skinner PJ, Koshy BT, Cummings CJ, Klement IA, Helin K, Servadio A, Zoghbi HY, Orr HT Ataxin-1 With an Expanded Glutamine Tract Alters Nuclear Matrix-Associated Structures.  Nature 1997; 389: 971-974. doi:10.1038/40153,  Impact Factor 28.8, cited 507 times.  
  5. Klement IA / Skinner PJ*, Kaytor MD, Hong Y, Hersch SM, Clark HB, Zoghbi HY, and Orr HT Ataxin-1 nuclear localization and aggregation:  role in polyglutamine-induced disease in SCA1 transgenic mice. Cell 1998; 95: 41-53. http://dx.doi.org/10.1016/S0092-8674(00)81781-X,  Impact Factor 30, cited 876 times.   *Co-first authors. 
  6. Kaytor MD, Duvick LA, Skinner PJ, Koob MD, Ranum LPW, and Orr HT. Nuclear localization of the spinocerebellar ataxia type 7 protein, ataxin-7. Human Molecular Genetics 1999; 8(9): 1657-1664. Impact Factor 7.8, cited 93 times.  
  7. Skinner PJ, Daniels MA, Schmidt CS, Jameson SC, and Haase AT. Cutting Edge:  In situ tetramer staining of antigen-specific T cells in tissues. Journal of Immunology 2000; 165 (2): 613 - 617 PMID: 18432944   Impact Factor 6.1, cited 130 times. 
  8. Fernandez-Funez P, Nino-Rosales ML, de Gouyon B, She WC, Luchak JM, Martinez P, Turiegano E, Benito J, Capovilla M, Skinner PJ, McCall A, Canal I, Orr HT, Zoghbi HY, and Botas J. Identification of genes that modify ataxin-1-induced neurodegeneration.  Nature 2000; 408:101-6,doi:10.1038/35040584. Impact Factor 29, cited 525 times. 
  9. Skinner PJ/Vierra-Green CA*, Clark HB, Zoghbi HY, and Orr HT.  Altered trafficking of membrane proteins in Purkinje cells of SCA1 transgenic mice.  American Journal of Pathology.  2001; 59, 905-13.  Impact Factor 5.5, cited 72 times.  *Co-first authors.
  10. Mothé BR, Horton H, Carter DK,  Liebl ME, Skinner P J, Allen TM, Vogel TU, Franchini G, Rehrauer W, Wilson N, Altman J D, Haase AT, Picker LJ, Sette AD, Watkins DI.  Dominance of CD8 Responses Specific for Epitopes Bound by a Single MHC Class I Molecule During Both the Acute and Chronic Phases of Viral Infection. Journal of Virology 2002; 76(2): 875-84.  PMC136839  Impact Factor 5.3, cited 136 times.   
  11. Skinner PJ, Vierra-Green CA, Emamian E, Zoghbi HY, Orr HT.  Amino acids in a region of ataxin-1 outside of the polyglutamine tract influence the course of disease in SCA1 transgenic mice. Neuromolecular Medicine 2002; 1(1): 33-42. Impact Factor 2.5, cited 23 times.
  12. Skinner PJ, and Haase AT. In situ tetramer staining.  Journal of Immunological Methods. 2002; 268(1):29-34. Impact Factor 2, cited 35 times.
  13. Pamela J. Skinner* and Ashley T. Haase.  In situ staining using MHC class I tetramers.  Current Protocols in Immunology, 17.4.1-17.4.9, 2004. Cited 9 times.
  14. Matthew R. Reynolds, Eva Rakasz, Pamela J. Skinner, Cara White, Kristina Abel, Min Ma, Lara Compton, Gnankang Napoé, Nancy Wilson, Christopher J. Miller, Ashley Haase, David I. Watkins.  The CD8+ T-Lymphocyte Response to Major Immunodominant Epitopes after Vaginal Exposure to SIV: Too Late and Too Little.  Journal of Virology, 2005 Jul;79(14):9228-35, PMC1168786.  Impact Factor 5.3, cited 147 times.
  15. Pamela J. Skinner*. Chapter 14: In situ tetramer staining. Monitoring T cell directed vaccine trials in cancer patients:  How to analyze cellular immune responses against tumor associated antigens, Dirk Nagorsen and Francesco Marincola, eds., Kluwer Publishing Group, 2005, DOI: 10.1007/1-4020-3623-X_12.
  16. Pamela J. Skinner*, Hayet Abbassi, Bruce Chesebro, Richard Race, Cavan Reilly, and Ashley T. Haase.  Gene expression alterations in brains of mice infected with three strains of scrapie. BMC Genomics; 7(114), 2006. PMCID: PMC1475852.  Impact Factor 4.2, cited 64 timesThe journal BMC Genomics featured this paper on its website and has permanently labeled this paper as “Highly Accessed” to identify that this article has been especially highly accessed, relative to its age.   
  17. Elizabeth Connick,  Terri Mattila, Joy M. Folkvord,  Rick Schlichtemeier,  Amie L. Meditz,  Aaron Hage, Cara White, and Pamela J. Skinner.  CTL Fail to Accumulate at Sites of HIV-1 Replication in Lymphoid Tissue, Journal of Immunology, 2007; 178(11): 6975-6983. PMID: 17513747 Impact Factor 6.1, cited 39 times.
  18. Hyeon O. Kim, Greg Snyder, Tyler M. Blazey, Bruce Chesebro, Richard E. Race, and Pamela J. Skinner*, Prion disease induced alterations in gene expression in the spleen and brain prior to clinical symptoms.  Computational Biology and Chemistry, 2008; 1:29-50, PMC3169940. PMID: 21918605   Impact factor 1.7, cited 11 times. 
  19. Meritxell Genescà, Pamela J. Skinner, Kristen M. Bost, Ding Lu, Yichuan Wang, Tracy L. Rourke, Ashley T Haase, Michael B. McChesney, Christopher J. Miller.  Protective attenuated lentivirus immunization induces polyfunctional SIV-specific T cells in the vagina and lymphoid tissues of rhesus macaques, Mucosal Immunology, 2008; 1(3):  219-228.  PMID:19079181  Impact factor 3.6, cited 40 times.
  20. Justin M. Greene, Benjamin J. Burwitz, Alex J. Blasky, Teresa L. Mattila, Jung Joo Hong, Eva G. Rakasz, Roger W. Wiseman, Kim J. Hasenkrug, Pamela J. Skinner, Shelby L. O'Connor, David H. O'Connor, Allogeneic Lymphocytes Persist and Traffic in Feral MHC-Matched Mauritian Cynomolgus Macaques, PLoS-ONE, 2008; 3(6): e2384. PMID:18545705   Impact factor 4.4, Cited 15 times.
  21. Meritxell Genescà, Pamela. J. Skinner, Jung Joo Hong, Jun Li, Ding Lu, Michael B. McChesney, Christopher J. Miller, With minimal systemic T-cell expansion, CD8+ T Cells mediate protection of rhesus macaques immunized with attenuated simian-human immunodeficiency virus SHIV89.6 from vaginal challenge with simian immunodeficiency virus.  Journal of Virology, 2008.  Nov; 82(22):11181-96, PMC2573271. Impact Factor 5.3, cited 40 times.
  22. Jung Joo Hong, Teresa L. Mattila, Aaron Hage, Matthew R. Reynolds, David I. Watkins, Christopher J. Miller, and Pamela J. Skinner*, Localized Populations of CD8Low/- MHC Class I Tetramer+ SIV-Specific T Cells in Lymphoid Follicles and Vaginal Epithelium of SIV infected macaques.  PloS ONE, 2009; 4(1): e4131, PMID: 19122815.  Impact factor 4.4, Cited 11 times.
  23. Qingsheng Li, Pamela J. Skinner, Sang-Jun Ha, Lijie Duan, Teresa L. Mattila, Aaron Hage, Cara White, Daniel L. Barber, Leigh O’Mara, Peter J. Southern, Cavan S. Reilly, Christopher J. Miller, Rafi Ahmed and Ashley T. Haase, Visualizing antigen specific and infected cells in situ predicts outcome in early viral infection.  Science, 2009; 323(5922):1726-1729, PMC2753492. Impact Factor 26, cited 134 times.
  24. Qingsheng Li, Pamela J. Skinner, Lijie Duan, and Ashley T. Haase, A Technique to Simultaneously Visualize Virus-Specific CD8+ T Cells and Virus-Infected Cells in situ, Journal of Visualized Experimentation, 2009; 30. PMID: 19684569  Viewed 28,002 times, cited 3 times.
  25. Ping Wang, Kristen Hatcher, Jason Bartz, Shu G Chen, Pamela J Skinner, Juergen A. Richt, Hong Liu, and Srinand Sreevatsan, Selection and Characterization of Aptamers against PrPSc, Exp Biol Med. 2011; 236:466-476. PMID: 21444369. Cited 10 times
  26. Lara Vojnov, Mauricio A. Martins, Jorge R. Almeida, Zachary Ende, Eva G. Rakasz , Matthew R. Reynolds, Enrique J. Leon, Kim L. Weisgrau, Benjamin J. Burwitz, Joy M. Folkvord, Marlon G. Veloso de Santana, Patrícia C. Costa Neves, Elizabeth Connick, Pamela J. Skinner, Emma Gostick, David H. O'Connor, Nancy A. Wilson, Myrna C. Bonaldo, Ricardo Galler, David A. Price, Danny C. Douek, David I. Watkins, Gag181-189CM9 -specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo, PloS ONE, 2011; 6(8): e23515. PMID: 21887264 Impact factor 4.4, Cited 6 times.
  27. Arun K. Sasikala-Appukuttan, Hyeon O. Kim, Nikilyn J. Kinzel, Jung Joo Hong, Anthony J. Smith, Reece Wagstaff, Cavan Reilly, Michael Piatak, Jr.,  Jeffrey D. Lifson, R. Paul Johnson , Ashley T . Haase, and Pamela J. Skinner*, Location and dynamics of the immunodominant CD8 T cells response to SIVnef immunization and SIVmac251 vaginal challenge, PLoS ONE 2013; 8(12): e81623. doi:10.1371/journal.pone.0081623. Cited 6 times.
  28. Skinner PJ*, Connick E, Overcoming the Immune Privilege of B cell Follicles to Cure HIV-1 Infection. J Hum Virol Retrovirol 2014, 1(1): 00001. DOI: 10.15406/jhvrv.2014.01.00001. Cited 1 time.
  29. Qingsheng Li, Ming Zeng, Lijie Duan, James E. Voss, Anthony J. Smith, Stefan Pambuccian, Liang Shang, Stephen Wietgrefe, Peter J. Southern, Cavan S. Reilly, Pamela J. Skinner, Mary L. Zupancic, John V. Carlis, Michael Piatak, Jr., Diane Waterman, R. Keith Reeves, Katherine Masek-Hammerman, Cynthia A. Derdehn, Michael D. Alpert, David T. Evans, Sybille Muller, James Robinson, Jeffrey D. Lifson, Dennis R.Burton, R. Paul Johnson, and Ashley T. Haase, Live Simian Immunodeficiency Virus Vaccine Correlate of Protection: Local Antibody Production and Concentration on the Path of Virus Entry, Journal of Immunology 2014; 193:3113-3125. Cited 2 times.
  30. Elizabeth Connick, Joy M. Folkvord, Katherine T. Lind, Eva G. Rakasz, Brodie Miles, Nancy A. Wilson, Mario L. Santiago, Edward B. Stephens, Hyeon O. Kim, Reece Wagstaff, Shengbin Li, Hadia M. Abdelaal, Nathan Kemp, David I. Watkins, Samantha MaWhinney, and Pamela Skinner, Compartmentalization of SIV Replication within Secondary Lymphoid Tissues of Rhesus Macaques is Linked to Disease Stage and Inversely Related to Localization of Virus-Specific CTL, Journal of Immunology, 2014 193:5613-5625; PMID:25362178
  31. Hadia M. Abdelaal, Hyeon O. Kim, Reece Wagstaff, Ryoko Sawahata, Peter J. Southern, and Pamela J. Skinner*, Comparison of Vibratome and Compresstome sectioning of fresh primate lymphoid and genital tissues for in situ MHC-tetramer and immunofluorescence staining, Journal of Biological Procedures Online, 2015; 17(1), 2. doi:10.1186/s12575-014-0012-4
  32. Pamela J. Skinner*, Hyeon O. Kim, Nikilyn J. Kinzel, Cavan Reilly, and Katherine Olson, Treatment of Prion Disease with Heterologous Recombinant Prion Proteins, submitted to PLOS ONE and presently responding to reviewer comments.
  33. T. Dileepan1, Hyeon O Kim2, James J Moon, Jonathan L Linehan, Marc K. Jenkins, P. Patrick Cleary, and Pamela J Skinner*, In Situ peptide-MHC-II Tetramer Staining of Antigen-Specific CD4+ T Cells in Tissues, Manuscript submitted to PLOS ONE, 2014  presently responding to reviewer comments.
  34. Kathryn A. Fraser, Jason M. Schenkel, Reece Wagstaff, Ryoko Sawahata, Lalit K. Beura, Katherine A. Staskus, Robert A. Seder, Roger W. Wiseman, David H. O’Connor, C.Y. Kang, Jonathan W. Yewdell, James S. Gibbs, Barbara K. Felber, George N. Pavlakis, Jake Yalley-Ogunro, Mark Lewis, Jeffrey D. Lifson, Michael Piatak Jr., Vaiva Vezys, Pamela J. Skinner, Ashley T. Haase, David Masopust, T cell vaccine that establishes abundant mucosal memory protects against SIV. Submitted to Nature, 2014.
  35. Brodie Miles, Shannon Miller, Joy M. Folkvord, Abigail Kimball, Mastooreh Chamanian, Amie L. Meditz, Tessa Arends, Martin D. McCarter, David N. Levy, Eva G. Rakasz, Pamela J. Skinner, and Elizabeth Connick, Follicular Regulatory T Cells Expand and Impair Follicular T Helper Cell Function in HIV and SIV Infection, submitted to Nature Immunology 2015
  36. Jung Joo Hong, Cara White, Ashley T. Haase, Christopher J. Miller, and Pamela J. Skinner*, Vaccine-Induced Protection is Associated with Little to No Perforin Expression within SIV-Specific CD8 T Cells, submitted

Poster presentations at National/International Meetings

  1. Skinner, P.J., Koshy, B.T., Cummings, C.J., Klement, I.A., Helin, K., Zoghbi, H.Y., and Orr, H.T. Mutant spinocerebellar ataxia type-1 gene product, ataxin-1, induces alterations in nuclear matrix associated structures. Huntington Disease Coalition for a Cure meeting of the Huntington's Disease Society of America, Santa Fe, New Mexico. 1997.
  2. Skinner, P., Cummings, C., Klement, I., Zoghbi, H., and Orr, H. Mutant SCA1 protein induces alterations in nuclear matrix associated structures."  Keystone Symposia, The Nuclear Matrix:  Involvement in Genomic Organization, Function and Cellular Regulation.  Copper Mountain, Colorado. 1998.
  3. Skinner, P.J., Clark, H.B., Cummings, C., Zu, T., Klement, I., Pinch, B., Zoghbi, H.Y., and Orr, H.T. Nuclear aggregation of mutant ataxin-1 is not required for SCA1 pathogenesis in mice.  Dynamic Organization of Nuclear Function meeting.  Cold Spring Harbor, New York. 1998.
  4. Skinner, P.J., Allen, T.M., Mothe, B.R., Watkins, D.I., and Haase, A.T. In situ tetramer staining of SIV specific T cells. Keystone Symposia, HIV Pathogenesis.  Keystone Colorado. 2001.
  5. Pamela J. Skinner, Bruce Chesebro, Rick Race, Karen Hsiao Ashe, and Ashley T. Haase Alterations in Gene Expression in Scrapie and Alzheimer’s Disease Mouse Models. Self-Perpetuating Structural States in Biology, Disease and Genetics.  National Academy of Sciences, Wash. D.C. 2002. 
  6. Pam Skinner, Hayet Abbassi, Bruce Chesebro, Rick Race, and Ashley Haase.  Gene Expression Alterations in Brains of Scrapie Infected Mice.  Keystone Symposium:  Molecular Aspects of Transmissible Spongiform Encephalopathies (Prion Diseases).  Colorado. 2003.
  7. Pam Skinner, Hayet Abbassi, Bruce Chesebro, Rick Race, Cavan Reilly, and Ashley Haase.  Gene Expression Alterations in Brains of Scrapie Infected Mice. Animal Prion Diseases in the America’s. Iowa. 2004
  8. E. Connick, J. Folkvord, T. Mattila, M. Givens, R. Schlichtemeier, M.G. Ray, P. Skinner. Heightened HIV RNA Production in Lymphoid Follicles (F) Coincides With Diminished Numbers of HIV-Specific CD8+ Cells at that Site.  12th Conference on Retroviruses and Opportunistic Infections.  Boston.  2005.
  9. Pamela J. Skinner, Teresa L. Mattila, Cara White, Aaron Hage, Ryan Sunderman, David I. Watkins, Christopher J. Miller, Elizabeth Connick, and Ashley T. Haase, Localized Populations of CD8- SIV-Specific T Cells in Lymphoid Follicles and Vaginal Epithelium, 13th Conference on Retroviruses and Opportunistic Infections, 2006.
  10. P Skinner, H Abbassi, B Chesebro, R Race, C Reilly, and A Haase, Gene expression alterations in brains of mice infected with three strains of scrapie, Keystone Symposium on Protein Misfolding Diseases, 2006.
  11. H. Kim, G. Snyder, H. Abbassi, B. Chesebro, R. Race, and P. Skinner. Gene expression alterations in both spleen and brain tissues of prion disease infected mice prior to the onset of clinical symptoms, Keystone Symposium on Molecular Mechanisms of Neurodegeneration, Taos, New Mexico, 2007.
  12. H. Kim, G. Snyder, H. Abbassi, B. Chesebro, R. Race, and P. Skinner. Scrapie induced altered gene expression in spleen and brain prior to clinical symptoms, Transmissible Spongiform Encephalopathies The Definitive American TSE Meeting, Baltimore, MD, 2007.
  13. Q. Li, P. Skinner, L. Duan, T. Mattila, C. Miller, A. T. Haase, A new experimental approach to analyzing in tissues the relationship between Simian Immunodeficiency Virus (SIV)-specific CD8+ T Cells and virus-infected-cells,  14th Conference on Retroviruses and Opportunistic Infections, 2007.
  14. Hyeon Kim, Greg Snyder, Richard E. Race, Bruce Chesebro, and Pam Skinner, Prion disease induced altered gene expression in spleen and brain prior to clinical symptoms.  Transmissible Spongiform Encephalopathies The Definitive American TSE Meeting, Baltimore, MD, 2008.
  15. Jung J. Hong, Teresa L. Mattila, Aaron Hage, Cara White, Hyeon O. Kim, Christopher J. Miller, Ashley T. Haase, and Pamela J. Skinner, Early Robust SIV-Specific CD8 T Cell Response Detected In Situ in Genital and Lymph Tissues from Macaques Infected with Attenuated SHIV and Subsequently Infected with Pathogenic SIV.  15th Conference on Retroviruses and Opportunistic Infections, Boston MA, 2008.
  16. Jung J. Hong, Teresa L. Mattila, Aaron Hage, Cara White, Hyeon O. Kim, Christopher J. Miller, Ashley T. Haase, and Pamela J. Skinner, Early Robust SIV-Specific CD8 T Cell Response Detected In Situ in Genital and Lymph Tissues from Macaques Infected with Attenuated SHIV and Subsequently Infected with Pathogenic SIV.  Keystone Symposium on HIV Pathogenesis, and HIV Vaccines:  Progress and Prospects, Banff Canada, 2008.
  17. Justin M. Greene, Benjamin J. Burwitz, Alex J. Blasky, Teresa L. Mattila, Jung Joo Hong, Eva G. Rakasz, Roger W. Wiseman, Kim J. Hasenkrug, Pamela J. Skinner, Shelby L. O'Connor, David H. O'Connor, Exploring protective vaccine-elicited immunity against SIV through adoptive transfers in Mauritian cynomolgus macaques.  26th Annual Symposium for Nonhuman Primate Models for AIDS. San Juan, Puerto Rico, 2008.
  18. Joy Folkvord, Amie Meditz, Martin McCarter, Pamela Skinner, Elizabeth Connick, The Follicular Homing Marker CXCR5 is Expressed by a Minority of Effector CD8+ Cells in HIV-1-Infected Lymph Nodes, 16th Conference on Retroviruses and Opportunistic Infections, Montreal Canada, 2009
  19. Dawn M. Dudley, Justin M. Greene, Melisa L. Budde, Niki Kinzel, Jung Joo Hong, Hyeon Kim, Pamela J. Skinner, and David H. O’Connor, In vitro modulation of integrin α4β7 does not traffic cells to the gut as efficiently as cells derived from gut-draining lymph nodes, Keystone Symposium 2010, Banff Canada.
  20. Jung Joo Hong, Cara White, Ashley T. Haase, Christopher J. Miller, and Pamela J. Skinner, Vaccine-Induced Protection is Associated with Little to No Perforin Expression within SIV-Specific CD8 T Cells, 17th Conference on Retroviruses and Opportunistic Infections, San Francisco, CA, 2010.  
  21. Hyeon O. Kim, Nikilyn Kinzel, Katherine Olson, and Pamela J. Skinner, Successful treatment of prion disease with heterologous recombinant prion proteins, Neuroscience, San Diego, CA, 2010
  22. T. Dileepan, Hyeon O Kim,  James J Moon, Jonathan L Linehan, Marc K. Jenkins, P. Patrick Cleary, and Pamela J Skinner,  In Situ peptide-MHC-II Tetramer Staining of Antigen-Specific CD4+ T Cells in Tissues, Immunology 2011, San Francisco, CA
  23. Arun K. Sasikala-Appukuttan, Hyeon O. Kim, Jung Joo Hong,  R. Paul Johnson, Ashley T . Haase, and Pamela J. Skinner, Location, abundance, and activation/proliferation status of SIV-specific CD8 T cells in situ in SIVnef immunized SIVmac251 challenged rhesus macaques, Keystone Symposia, Protection from HIV: Targeted Intervention Strategies, Whistler, British Columbia, 2011
  24. Lara Vojnov, Mauricio Martins, Alex Bean, Holly L. Kolar, Eva G. Rakasz, Matt Reynolds, Enrique Leon, Jorge Almeida, Joy M. Folkvord, Elizabeth Connick, Pamela J. Skinner, Nancy A. Wilson, Ashley T. Haase, Mario Stevenson, Danny Douek, David I. Watkins, SIV-specific Gag181-189CM9 CD8+ T cells fail to suppress viral replication in vivo and in macrophages in vitro, Keystone Symposia, Protection from HIV: Targeted Intervention Strategies, Whistler, British Columbia, 2011
  25. Elizabeth Connick, Joy Folkvord, Katherine Lind, Eva Rakasz, Nancy Wilson, Mario Santiago, Edward Stephens, Hyeon Kim, Nikilyn Kinzel, Pamela Skinner, Failure of Virus-specific CTL to Accumulate in Lymphoid Follicles May Contribute to the Follicular Reservoir of SIV Replication in Chronic Infection, 19th Conference on Retroviruses and Opportunistic Infections, Seattle, WA, 2012
  26. Mohamed Mohamed, Arun K. Sasikala-Appukuttan, Hyeon O. Kim, and Pamela J. Skinner, Phenotypic changes and proliferation status of SIV-specific CD8+ T cells in response to SIVnef immunized SIVmac251 challenged rhesus macaques, Emerging Researchers National Student Conference, Atlanta, GA, 2012
  27. Preethi Haran, Eva Rakasz, Kirti Kaushik, Joy Folkvord, R. Scott McIvor, Todd A. Reinhart, Elizabeth Connick, and Pamela J. Skinner, Transduction of primary rhesus macaque CD8 T cells with the B cell homing molecule CXCR5, Keystone Symposia: HIV Pathogenesis, Banff Canada, 2014
  28. Shengbin Li , Hyeon Kim, Reece K Wagstaff, Ryoko Hatsugai, Eva G Rakasz, Elizabeth Connick, and Pamela J Skinner, Location, abundance, and phenotype of follicular SIV-specific CTL during chronic infection, Keystone Symposia: Mechanisms of HIV Persistence: Implications for a Cure, Boston, MA, 2015

Poster Presentations at Regional Meetings

  1. Brian Hardy, Hayet Abbassi, Karen Hsiao Ashe, and Pam Skinner.  Identification of gene expression alterations in brains of Alzheimer disease mice.  University of Minnesota College of Veterinary Medicine Points of Pride Research Day Symposium, 2004.  Won Best Poster Award.
  2. Jennifer Wicklund, Hayet Abbassi, and Pam Skinner.  Gene Expression Alterations in Prion Disease. University of Minnesota College of Veterinary Medicine Points of Pride Research Day Symposium, 2004.
  3. Terri Mattila and Pam Skinner.  Developing TSE-Specific Diagnostic Microarrays.  University of Minnesota College of Veterinary Medicine Points of Pride Research Day Symposium, 2004.
  4. Jill M. Grandt, Ryan M. Sunderman, Cara B. White, Ashley T. Haase, and Pamela J. Skinner.  Evaluation of Perforin in SIV Specific CD8+ T cells.  UMN Undergraduate Poster Symposium, 2004. 
  5. Kuwe Edossa, Terri Matilla, and Pam Skinner.  DNA Microarrays to Diagnose Transmissible Spongiform Encephalopathies.  Life Sciences Summer Undergraduate Research Program Poster Symposium, 2004.
  6. Aaron Hage and Pamela J. Skinner.  Evaluation of Perforin Exhaustion in SIV Specific CD8+ T cells, UMN Undergraduate Poster Symposium, 2005.
  7. Lien Duong, Rebecca Merica, and Pam Skinner.  Diagnosing Transmissible Spongiform Encephalopathies (Prion Diseases) Using DNA Microarrays, UMN Undergraduate Poster Symposium, 2005.
  8. Greg Snyder, Hayet Abbassi, Bruce Chesebro, Richard E. Race, Ashley T. Haase,   Pamela J. Skinner, Pre-symptomatic Alterations in Gene Expression During Prion Disease, UMN Undergraduate Poster Symposium, 2005.
  9. Leah B. Christensen, Janna Hill, Greg Snyder, Archana Deshpande, and Pamela Skinner, Diagnostic Microarrays for Transmissible Spongiform Encephalopathies, UMN Undergraduate Poster Symposium, 2006.
  10. Colin Pierce, Hyeon O. Kim, Aaron Hage, and Pamela J. Skinner, T cell and B cell membrane mingling at the edges of B cell Follicles—implications for immune activation, University of Minnesota Undergraduate Research Symposium, 2007.
  11. Matthew Korthauer, Hyeon O. Kim, and, Pamela J. Skinner, Comparison of gene expression alterations in prion disease infected mice to during Theiler’s murine encephalomyelitis virus infected mice, University of Minnesota Undergraduate Research Symposium, 2007.
  12. T. Mattila, Q. Li, A. Hage, E. Connick, C. Miller, A. Haase, P. Skinner, In situ analysis of virus-specific CD8+ T cells, Keystone Symposium on HIV Vaccines: From Basic Research to Clinical Trials, Whistler, British Columbia, 2007.  Oral presentation and poster.
  13. Michelle A. Dina, Hyeon O. Kim, and Pamela J. Skinner, Alzheimer and prion disease-associated gene expression alterations in the brain.  University of Minnesota Undergraduate Research Symposium, 2008.
  14. Ellie M. Clarkson, Hyeon O. Kim, and Pamela J. Skinner, Comparison of gene expression alterations in prion disease-infected mice to Theiler’s murine encephalomyelitis-infected mice. University of Minnesota Undergraduate Research Symposium, 2008.
  15. John Haggart, Teresa L. Mattila, Aaron Hage, Jung Joo Hong, Hyeon O. Kim, and Pamela J. Skinner, HIV and SIV-specific T cells mingle with B cells indise and outside of B cell follicles.  University of Minnesota Undergraduate Research Symposium, 2008.
  16. Kaitlyn M. Inhoff, Hyeon O. Kim, and Pamela J. Skinner, Specificity of gene expression alterations in prion disease, University of Minnesota College of Veterinary Medicine Points of Pride Research Day Symposium, 2008.
  17. David C. Gemperline, Jung Joo Hong, Aaron Hage, and Pamela J. Skinner, Analysis of SIV-specific CD8+ T cell responses in SIV-infected macaques vaccinated with an attenuated SIV virus, Life Sciences Summer Undergraduate Research Symposium, 2008.
  18. Jung J. Hong, Teresa L. Mattila, Aaron Hage, Cara White, Hyeon O. Kim, Christopher J. Miller, Ashley T. Haase, and Pamela J. Skinner, Early Robust SIV-Specific CD8 T Cell Response Detected In Situ in Genital and Lymph Tissues from Macaques Infected with Attenuated SHIV and Subsequently Infected with Pathogenic SIV.  University of Minnesota College of Veterinary Medicine Points of Pride Research Day Symposium, 2008.
  19. Teresa Mattila, Joy Folkvord, Elizabeth Connick, and Pamela J. Skinner, The role of SIV-specific CD8 T cells in the establishment of persistent SIV infection, University of Minnesota College of Veterinary Medicine Points of Pride Research Day Symposium, 2008.  Won Best Poster Award
  20. Jung Joo Hong, Teresa L. Mattila, Aaron Hage, Matthew R. Reynolds, David I. Watkins, Christopher J. Miller, and Pamela J. Skinner, Localized Populations of CD8- SIV-Specific T Cells in Lymphoid Follicles and Vaginal Epithelium of SIV infected macaques. University of Minnesota College of Veterinary Medicine Points of Pride Research Day Symposium, 2009.
  21. Vanesa Laboy, Jake Kurth, Hyeon O. Kim, and Pamela J. Skinner, In situ analysis of virus-specific CD8 T cells in a simian model of HIV infection, Life Sciences Summer Undergraduate Research Program Symposium 2009.
  22. Justin Martinez, Kathy Olson, Hyeon Kim, Ellie Clarkson, Michelle Dina, and Pamela Skinner, Alterations in Gene Expression Levels During Prion Disease: Specificity and use as biomarkers for early prion disease diagnosis, University of Minnesota Undergraduate Research Symposium, 2009.
  23. Gregory R. Crane Katherine E. Olson, and Pamela J. Skinner.  Quantitative PCR Analysis of mRNA Concentrations in Brain Cells of Transgenic Alzheimer’s Disease Mice, University of Minnesota Chemistry Symposium 2009.
  24. Kristopher Schwebler, Jung Joo Hong, Hyeon O. Kim, and Pamela J. Skinner, Protective Immunity Provided by Live, Attenuated SIVΔnefVaccination Is Associated with SIV-Specific CD8+T Cells that Express Little or No Perforin, University of Minnesota Undergraduate Research Symposium, 2010.
  25. Lauren E. Roach, Hyeon O. Kim, Jung Joo Hong & Pamela J. Skinner, Little to no granzyme B expression in SIV-specific CD8+ T cells correlates with an effective SIV vaccine, University of Minnesota Undergraduate Research Symposium, 2010.
  26. Jake Kurth, Joy Folkvord, Lara Vojnov, Jeremy Herrera, Hyeon O.  Kim, Jung Joo Hong, David Watkins, Elizabeth Connick, and Pamela J. Skinner, Vaccine failure may be due to failure of SIV-specific CD8 T cells to migrate to and kill SIV producing cells inside B-cell follicles, University of Minnesota Undergraduate Research Symposium, 2010.
  27. Katherine L. Doll, John Haggart, Hyeon O. Kim, and Pamela J. Skinner, Virus-specific CD8 T cells mingle membranes with B cells, University of Minnesota Undergraduate Research Symposium, 2010.
  28. Mohamed Ameen, Arun K. Sasikala-Appukuttan, Hyeon O. Kim, and Pamela J. Skinner, Phenotypic changes and proliferation status of SIV-specific CD8+ T cells in response to SIVnef immunized SIVmac251 challenged rhesus macaques, Emerging Researchers National Student Conference, Atlanta, GA, 2012
  29. Mira Hager, Elizabeth Connick, Pamela Skinner, Perforin expression in lymph node tissues of HIV positive individuals, Summer Undergraduate Research Symposium, UMN, 2012.
  30. Jaleesa Morris, Preethi Haran, Elizabeth Connick, and Pamela Skinner , Summer Undergraduate Research Symposium , UMN, 2012
  31. Nathan Kemp, Reece Wagstaff, Hadia Mohammed, Emily Thompson, Rafael Barbosa, Teresa Mattila,  Hyeon Kim, Liz Connick, Eva Rakasz and Pamela Skinner, Abundance of SIV-specific CTL inside and outside of B cell follicles during chronic SIV infection,  Summer Undergraduate Research Symposium, UMN, 2013.
  32. Sarah Armstron-Serbus, Marta Borgeson, Nicole Andrews, Michelle Kotlovich, Pat Goodman-Mamula, Martin Wolf, and Pamela Skinner, Student Research Proposals: In Their Own Words (VBS 1001), College of Veterinary Medicine Education Day, University of Minnesota, 2013.
  33. Martin Wolf, Patricia Goodman-Mamula and Pamela Skinner,  Having the Supreme Court come to your Class, College of Veterinary Medicine Education Day, University of Minnesota, 2013.
  34. Justin Jacques, Preethi Haran, Pamela Skinner, Triple transfection of 293T cells using recombinant plasmid DNA for production of CXCR5 transducing lentivirus. University of Minnesota Undergraduate Directed Research Symposium, 2013
  35. Sarah Armstron-Serbus, Marta Borgeson, Nicole Andrews, Michelle Kotlovich, Pat Goodman-Mamula, Martin Wolf, and Pamela Skinner, Student Research Proposals: In Their Own Words (VBS 1001), 2013 Academy of Distinguished Teachers Conference: Teaching and Learning in Changing Times, Johnson McNamara Alumni Center, University of Minnesota, 2013
  36. Martin Wolf, Patricia Goodman-Mamula and Pamela Skinner,  Having the Supreme Court come to your Class, 2013 Academy of Distinguished Teachers Conference: Teaching and Learning in Changing Times, Johnson McNamara Alumni Center, University of Minnesota, 2013  Presented both as a poster as well as orally.
  37. Justin Jacques, Preethi Haran, and Pamela Skinner, Fresh Tissue Migration Assay of Rhesus Macaque Tissue Incubated with CFSE Labeled PBMCs and Lymph Node Cells, University of Minnesota UROP Program, 2013
  38. Patricia Goodman-Mamula, Ashley Melco, Mackenzie Webster, Martin Wolf and Pamela J. Skinner, Introduction to Biotechnology (VBS 1001):  A Visual Guide to Student Research Presentations, University of Minnesota, College of Veterinary Medicine Education Day 2014.

Oral Presentations

  1. Pamela Skinner, “Nuclear aggregation of mutant ataxin-1 is not required for SCA1 pathogenesis in mice”.  Dynamic Organization of Nuclear Function meeting.  Cold Spring Harbor, New York. 1998.
  2. Pamela Skinner, “Emerging techniques and approaches for TSE diagnosis”, UMN TSE Workshop:  TSEs their impact on human and animal health, environment and economics:  How do respond? 2003.
  3. Pamela Skinner, “To Be or Not To Be:  DNA Microarrays to Diagnose Prion Diseases”, UMN Molecular Veterinary Biosciences Seminar, 2003.
  4. Pamela Skinner, “DNA Microarrays to Diagnose Prion Diseases”, Minnesota Supercomputer Institute (MSI) Seminar, 2003.
  5. Pamela Skinner, “DNA Microarrays to Diagnose Prion Diseases”, UMN Microbiology Immunology and Cancer Biology Seminar, 2003.
  6. Pamela Skinner, “Gene expression alterations in asymptomatic and symptomatic scrapie infected mice”, NC-505 Domestic Surveillance, Diagnosis, and Therapy of Transmissible Spongiform Encephalopathies Meeting, 2004.
  7. Pamela Skinner, “Gene expression alterations in the brains of scrapie infected mice”, NIH, NIAID, Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, Montana 2004
  8. Pamela Skinner, “In vivo analysis of HIV and SIV specific CD8+ T cells”, University of Colorado Health Sciences Center, Infectious Disease Grand Rounds, Colorado 2005
  9. Pamela Skinner, “Localized Populations of CD8-  SIV-Specific T Cells in Lymphoid Follicles and Vaginal Epithelium”, 13th Conference on Retroviruses and Opportunistic Infections, Colorado 2006.
  10. Pamela Skinner, “Transmissible Spongiform Encephalopathies (Prion Diseases)”, UMN Microbiology Club, 2006.
  11. Pamela Skinner, “Spleen and brain gene expression alterations in asymptomatic and symptomatic scrapie-infected”.  NC124 meeting:  Domestic Surveillance, Diagnosis, and Therapy of TSEs, Minnesota, 2007.
  12. Pamela Skinner, “The role of HIV- and SIV-specific CD8 T cells in persistent infection and a successful vaccine”.  UMN Institute for Molecular Virology, 2008.
  13. Pamela Skinner, “The ups and downs of gene expression during prion disease”, NC124 meeting:  Domestic Surveillance, Diagnosis, and Therapy of TSEs, Montana 2008.
  14. Pamela Skinner, “The role of HIV- and SIV-specific CD8 T cells in persistent infection and a successful vaccine”, Graduate Women in Science Meeting, MN Chapter, 2008.
  15. Pamela Skinner, “The ups and downs of gene expression during prion disease”, University of Minnesota Comparative and Molecular Biology Program, 2008.
  16. Pamela Skinner, “In situ analysis of SIV-specific CD8 T cells:  2008 IAVI study”, International Aids Vaccine Initiative Live Attenuated Consortium --Laboratory Without Walls (LACLWOW) Retreat, UMN 2008. 
  17. Pamela Skinner, “Insights into prion disease pathogenesis and treatment”, Graduate Student Invited Speaker, University of Utah, 2011.
  18. Pamela Skinner, “Location, abundance, and activation/proliferation status of SIV-specific CD8  T cells in situ in SIVnef immunized, SIVmac251 challenged rhesus macaques”, American Society for Virology, 2011.
  19. Pamela Skinner, “Location, abundance, and activation/proliferation status of SIV-specific CD8  T cells in situ in SIVnef immunized, SIVmac251 challenged rhesus macaques”, Keystone Symposia, Protection from HIV: Targeted Intervention Strategies, Whistler, British Columbia, 2011.
  20. Pamela Skinner, “Location, abundance, and phenotype of HIV and SIV-specific CD8 T cells in persistent infection, successful vaccination, and immunotherapy”, Center for Infectious Disease and Microbiology Translational Research, UMN, 2012.
  21. Pamela Skinner, “Location, abundance, and phenotype of HIV and SIV-specific CD8 T cells in persistent infection, successful vaccination, and immunotherapy”, AIDS Vaccine Research Laboratory, University of Wisconsin, Madison, 2013.
  22. Pamela Skinner, “Prion disease pathogenesis and treatment”, PharmacoNeuroImmunogy Program, University of Minnesota, 2013.
  23. Pamela Skinner, “The long and winding road to an HIV vaccine”, Health Care Education and Training, Minnesota Reproductive & Sexual Health Update, University of Minnesota, 2013.
  24. Pamela Skinner, "CTL and the follicular reservoir of HIV," Graduate Student Invited Speaker, UMN College of Veterinary Medicine Research Seminar, 2015.

 

Pamela J Skinner, PhD

Associate Professor of Vet Biomedical Science

 

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  • :612-625-5203

  • DEPARTMENTUniversity of Minnesota
  • COUNTRYUSA