Research Interest

  • Basic research into analysis of causal variants responsible for human autoimmune diseases such as Ankylosing Spondylitis
  • Basic Immunology research of interactions between  the innate and adaptive immune systems
    Basic Research into several aspects of Gene transfer based therapy, both virus-mediated, and non-virus mediated.
  • T1 research translating laboratory findings into the clinical realm, primarily in regard to immunomodulatory strategies to treat various forms of cancer, as well infectious and  inherited or acquired diseases.
  • Research into basic physiology of Duchenne Muscular Dystrophy/Glycogen storage disease Type II/Pompe disease/musculoskeletal disorders, with a goal towards T1 research.
  • Clinical enzyme replacement trials and therapy in Infantile GSD-II/Pompe disease, and other  lysosomal storage diseases
  • Applied Gene therapy in several  human diseases.
  • Use of gene transfer to treat cancers, to augment anti-cancer immunity.
  • Genetic Vaccine development for use in infectious diseases.
  • Use of animal models of human disease to predict clinical outcomes of potential therapies.
  • Understanding innate and adaptive immune responses to gene transfer
  • Clinical Dysmorphology and syndrome classification/identification
  • Pre-emptive clinical strategies for patients affected by any variety of genetic diseases.


Andrea Amalfitano



  • : 1-517-884-5324
  • : 1-517-353-8957

  • DEPARTMENTDepartment of Microbiology and Molecular Genetics
    College of Osteopathic Medicine
    Michigan State University