1. Hollister, K., Chen, Y., Wang, S., Wu, H., Mondal, A., Clegg, N., Lu, S., Dent, A.L. “The role of follicular helper T cells and the germinal center in HIV-1 gp120 DNA prime and gp120 protein boost vaccination”, HVIT 10: 1985–1992 (2014) (PMC in process)
  2. Hollister, K., Kusam, S., Wu, H., Clegg, N., Mondal, A., Sawant, D. and Dent, A.L. "Insights into the Role of Bcl6 in Follicular Helper T Cells Using a New Conditional Mutant Mouse Model" J. Immunol. 191:3705-11 (2013) (PMC3783642)
  3. Sawant, D.V., Sehra, S., Nguyen, E. T., Jadhav, R., Englert, K., Shinnakasu, R., Hangoc, G., Broxmeyer, H.E., Nakayama, T., Perumal, N.B., Kaplan, M.H., Dent, A.L."Bcl6 Controls the Th2 Inflammatory Activity of Regulatory T Cells by Repressing Gata3 Function" J. Immunol., 189: 4759-4769 (2012) (PMC3490013)           
  4. Sawant, D., Mondal, A. and Dent, A.L."The Transcriptional Repressor BCL6 Controls Th17 Responses by Controlling Gene Expression in Both T cells and Macrophages" J. Immunol. 184: 4123-32 (2010) PMID: 20212093 (free full text)
  5. Johnston, R.J., Poholek, A.C., Yusuf, I., DiToro, D., Eto, D., Barnett, B., Dent, A.L., Craft, J. and S. Crotty. “Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of follicular helper (Tfh) CD4 T cell differentiation”, Science, 325:1006-1010 (2009) (PMC2766560)

Additional publications of importance to the field (in chronological order)

  1. Dent, A., A. Shaffer, D. Allman, X. Yu, and L. M. Staudt. “Control of inflammation, cytokine expression, and germinal center formation by BCL-6”. Science, 276: 589  (1997). PMID: 9110977 (free full text)
  2. Dent, A. L., J. Hu-Li., W.E. Paul, and L.M. Staudt. “T helper type 2 inflammatory disease in the absence of interleukin 4 and STAT6”, Proc. Natl. Acad. Sci. USA ,  95: 13823 (1998). (PMC24910)
  3. Toney, L.M., Cattoretti, G., Graf, J.A., Merghoub, T., Pandolfi, P.-P., Dalla-Favera, R.D., Ye, B.H., and Dent, A.L.  "BCL-6 Regulates Chemokine Gene Transcription in Macrophages" Nat. Immunol., 1, 214 (2000). PMID: 10973278
  4. Poholek, A.C., Hansen, K., Hernandez, S.G., Eto, D., Chandele, A., Weinstein, J.S., Dong, X., Odegard, J.M., Kaech, S.M., Dent, A.L., Crotty, S. and Craft, J.  “In vivo regulation of Bcl6 and T follicular helper cell development” " J. Immunol. 185: 313-326 (2010) (PMC2891136)
  5. Kusam S., Toney L.M., Sato H. and Dent, A.L. "Inhibition of Th2 differentiation and GATA-3 expression by BCL-6" J. Immunol. 170: 2435-2441 (2003). PMID: 12594267 (free full text)
  6. Kusam, S., Vasanwala, F., and Dent, A.L. "The Transcriptional Repressor BCL-6 Immortalizes Germinal Center-like B Cells in the Absence of p53 Function”, Oncogene 23: 839-844 (2004). PMID: 14737119
  7. Sehra S., Patel D., Kusam S, Wang Z.-Y., Chang C.-H.C. and Dent A. L. "A Role for  Caspases in Controlling IL-4 Expression by T Cells”, J. Immunol. 174: 3440-3446 (2005). PMID: 15749878 (free full text)
  8. Wang Z.-Y.,  Sato H., Kusam S., Sehra S., Toney L. M., and Dent A.L. "Regulation of IL-10 Gene Expression in T Helper Type 2 Cells by Jun Proteins”, J. Immunol. 174: 2098-2105 (2005). PMID: 15699140 (free full text)
  9. Wang, Z.-Y., Kusam, S., Munugalavadla, V., Kapur, R., Brutkiewicz R. R. and Dent. A. L.  “Regulation of Th2 Cytokine Expression in NKT Cells: Unconventional Utilization of Stat6, GATA-3 and NFAT2”, J. Immunol. 176: 880-888 (2006). PMID: 16393972  (free full text)
  10. Broxmeyer, H.E., Sehra, S., Cooper, S., Toney, L.M., Kusam, S., Aloor, J.M., Marchal, C.C., Dinauer, M.C. and Dent, A.L. “BAZF-Deficient Mice Have Unusual Alterations in Hematopoietic Progenitor Cell Activity Similar to That of BCL6 Deficient Mice”, Mol. Cell. Biol., 15:5275-85 (2007) (PMC1952080)


Alexander Lloyd Dent

Associate Professor


  • : (317) 274-7524

  • DEPARTMENTDepartment of Microbiology & Immunology
    Indiana University School of Medicine