Publications

Books Edited

  • Pluripotent stem cell biology: Advances in mechanisms, methods and models. Editor, Craig S.Atwood and Sivan Vadakkadath Meethal (2014)InTech: Open Access Publisher,ISBN 978 953-51-1590-8, http://www.intechopen.com/books

Editorial

  • Vadakkadath Meethal, S., Hayashi, K. and Atwood, C.S. (2013). Human stem cell proliferation and differentiation: Lessens from a lost era of research. J Regen Med, 2:2    doi: 10.4172/2325-9620.1000e108

Peer-Reviewed Publications

  • Gallego, M.J., Porayette, P., Kaltcheva, M., Bowen, R.L., Vadakkadath Meethal, S. and Atwood, C.S. (2010). The pregnancy hormones human chorionic gonadotropin and progesterone induce human embryonic stem cell proliferation and differentiation into neuroectodermal rosettes. Stem Cell Research and TherapySep 13;1(5):28. [Epub ahead of print] (Listed under Vadakkadath Meethal S, PMID: 20836886)
  • Porayette, P., Gallego, M.J., Kaltcheva, M.M., Vadakkadath Meethal, S. and Atwood, C.S. (2009). Differential processing of amyloid-β precursor protein directs the proliferation and neuronal differentiation of human embryonic stem cells. Journal of Biological Chemistry284:23806-17(Listed under Vadakkadath Meethal S, PMID: 19542221)
  • Vadakkadath Meethal, S., Liu, T., Chan, H., Ginsburg, E., Wilson, A.C., Gray, D.N., Bowen, R.L., Vonderhaar, B. K. and Atwood, C.S. (2009). Identification of a regulatory loop for the synthesis of neurosteroids: a steroidogenic acute regulatory protein-dependent mechanism involving hypothalamic-pituitary-gonadal axis receptors. Journal of Neurochemistry110:1014-27(Listed under Meethal SV, PMID: 19493163)
  • Simon, D.P*.,Vadakkadath Meethal, S*., Gallego, M., Wilson, A.C., Weinecke, S.L., Lyons, P., Haasl, R.J., Bowen, R.L. and Atwood, C.S. (2009).Activin receptor signaling regulates prostatic epithelial cell adhesion and viability.Neoplasia, 11, 365-376 (*Co-first author; Listed under Vadakkadath Meethal S, PMID: 19308291)
  • Gallego, M.J., Porayette, P., Kaltcheva, M.M., Vadakkadath Meethal, S. and Atwood, C.S. (2009). Opioids and progesterone signaling is obligatory for early human embryogenesis. Stem Cell and Development Sep 19. (Listed under Meethal SV, PMID: 18803462)
  • Haasl, R.J., Ahmadi, M.R., Vadakkadath Meethal, S., Gleason, C.E., Johnson, S.C., Asthana, S., Bowen, R.L and Atwood, C.S.  (2008). A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer’s disease in males carrying an apolipoprotein E ε4 allele. BMC Medical Genetics.9, 37(Listed under Meethal SV, PMID: 18439297)
  • Wilson, A.C., Clemente, L., Liu, T., Bowen, R.L., Vadakkadath Meethal, S. and Atwood, C.S. (2008). Reproductive hormones regulate the selective permeability of the blood-brain barrier. BiochimicaetBiophysicaActa - Molecular Basis of Disease,1782, 401-7(Listed under Meethal SV, PMID: 18381207)
  • Porayette, P., Gallego, M.J., Kaltcheva, M.M., Vadakkadath Meethal, S. and Atwood, C.S (2007). Amyloid-beta precursor protein expression and modulation in human embryonic stem cells: a novel role for human chorionic gonadotropin.  Biochemical Biophysical Research Communications364, 522-7(Listed under Meethal SV, PMID: 17959150)
  • Vadakkadath Meethal, S., Potter, K.T., Redon, D., Wolff, M.R., Kamp, T.J., Valdivia, H.H and Haworth, R.A. (2007). Structure-function relationships of Ca spark activity in normal and failing cardiac myocytes as revealed by flash photography. Cell Calcium 41, 123-34 (Listed under Meethal SV, PMID: 16837043)
  • Wilson, A.C., Salamat, S., Roche, K.M., Karande, A., Vadakkadath Meethal, S., Smith, M.A., Terasawa, E., Bowen, R.L. and Atwood, C.S. (2006). Human neurons express type I GnRH receptor and respond to GnRH I by increasing luteinizing hormone expression. Journal ofEndocrinology 191, 651-663 (Listed under Meethal SV, PMID: 17170222)
  • Vadakkadath Meethal, S., Gallego, M.J., Haasl, R.J., Petras, S.J., Sgro, S.J., Bowen, R.L.  andAtwood, C.S. (2006). Identification of a gonadotropin-releasing hormone receptor orthologue in Caenorhabditiselegans. BMC Evolutionary Biology 29, 103 (Listed under Vadakkadath Meethal S, PMID: 17134503)
  • Lokuta, A.J., Maertz, N.A., Vadakkadath Meethal, S.,Potter, K.T., Redon, D., Rio, A.M., Kamp, T.J., Valdivia, H.H. and Haworth, R.A. (2005). Increased nitration of sarcoplasmic reticulum Ca2+-ATPase in human heart failure. Circulation 111, 988-95 (Listed under Meethal SV, PMID: 15710754)
  • Vadakkadath Meethal, S.,Potter, K.T., Redon, D., Heisey, D.M. and Haworth, R.A. (2004).   Ca transients from Ca channel activity in rat cardiac myocytes reveal dynamics of dyad cleft and troponin C Ca binding. American Journal of Physiology - Cell Physiology 286, C302-C316 (Listed under Vadakkadath Meethal S, PMID: 14534082)
  • Vadakkadath Meethal, S.and Kaleysa Raj, R. (1999). Quinone analogues irrecoverably paralyze the filarial parasites in vitro. Biochemical and Biophysical Research Communications 256, 81-83  (Listed under Sivan VM, PMID: 10066426)
  • Vadakkadath Meethal, S.and Kaleysa Raj, R. (1994). Lactate oxidation coupled to energy generation in mitochondria like particles from Setariadigitata, a filarial parasite.  Biochemical and Biophysical Research Communications 204, 17-22 (Listed under Sivan VM, PMID: 7945357)
  • Vadakkadath Meethal, S.and Kaleysa Raj, R. (1992). Quinone dependent NADH dehydrogenation in mitochondria like particles from Setariadigitata, a filarial parasite. Biochemical and Biophysical Research Communications 186, 698-705 (Listed under Sivan VM, PMID: 1497658)
Reviews
  • Vadakkadath Meethal, S., Hogan, K.J., Mayanil, C.S. and Iskandar, B.J (2013). Folate and epigenetic mechanisms in neuraltube development and defects. Child NervSyst 29, 1427-1433 (Listed under Meethal SV, PMID: 24013316)
  • Vadakkadath Meethal, S. and Atwood, C.S. (2010). Lactate dyscrasia: A novel explanation for amyotrophic lateral sclerosis. Neurobiology of Aging Jun 10[Euub ahead of print] (Listed under Vadakkadath Meethal S, PMID: 20541840)
  • Wilson, A.C., Vadakkadath Meethal, S., Bowen, R.L. and Atwood, C.S. (2007). Leuprolide acetate: a drug of diverse clinical applications. Expert Opinion on Investigational Drugs 16, 1851-63(Listed under Meethal SV, PMID: 17970643)
  • Vadakkadath Meethal, S., Smith, M.A., Boven, R.L. and Atwood, C.S. (2005). The gonadotropin connection in Alzheimer’s disease. Endocrine, 26, 317-26 (Listed under Meethal SV, PMID: 16034187)
  • Atwood, C.S., Vadakkadath Meethal, S., Liu, T., Wilson, A.C., Gallego, M., Smith, M.A. and Bowen, R.L. (2005). Dysregulation of the hypothalamic-pituitary-gonadal axis with menopause and andropause promotes neurodegenerative senescence. Journal of Neuropathology and Experimental Neurology 64, 93-103 (Listed under Meethal SV, PMID: 15751223)
  • Vadakkadath Meethal, S.and Atwood, C.S. (2005).The role of hypothalamic- pituitary gonadal hormones in the normal structure and functioning of the brain. Cellular and Molecular Life Sciences 62, 257-270 (Listed under Vadakkadath Meethal S, PMID: 15723162)

Book chapters

  • Atwood, C.S. and Vadakkadath Meethal, S. (2011).  Human Embryonic Stem Cells as a Model System for Understanding Early Human Embryogenesis and Age-related Diseases. In: Embryonic Stem Cells. Ed. Craig S. Atwood.  InTech, Rijeka, Croatia. Chapter 14, 251-270.  ISBN: 978-953-307-196-1.
  • http://www.intechopen.com/articles/show/title/human-embryonic-stem-cells-a-model-system-for-delineating-the-molecular-basis-of-human-embryogenesis
  • Atwood, C.S. and Vadakkadath Meethal, S. (2011). Gonadotropins and Progestogens: Obligatory Developmental Functions during Early Embryogenesis and their Role in Adult Neurogenesis, Neuroregeneration, and Neurodegeneration.  In: Hormones in Neurodegeneration, Neuroprotection and Neurogenesis, Eds. AchilleGravanis and Synthia Mellon, WILEY-VCH Verlag GmbH & Co. KgaA, Weinheim, Germany.  Chapter 18, pp 305-319. ISBN: 978-3-527-31920-6.,
    http://onlinelibrary.wiley.com/doi/10.1002/9783527633968.ch18/summary
  • Vadakkadath Meethal, S., Porayette, P., Wilson, A.C., Basson, J., Liu, T. and Atwood, C.S. (2010). Functional consequences of gonadotropin signaling in the brain during development, adulthood and senescence, In: Gonadal and Nongonadal Actions of Gonadotropins. Narosa Publishing House Pvt. Ltd., New Delhi, India, Chapter 23, pp 249-274. ISBN (13): 9788173199837.,
    http://www.narosa.com/books_display.asp?catgcode=978-81-7319-983-7

 

 

 

Sivan Vadakkadath Meethal

Senior Scientist

 

  • : (608)-334-1702

  • DEPARTMENTDepartment of Medicine
    University of Wisconsin
  • COUNTRY USA