Publications

  • Zhou, S.Li, Y.Kestell, P.Schafer, P.Chan, E.Paxton, JW. Transport of thalidomide by the human intestinal caco-2 monolayers. European journal of drug metabolism and pharmacokinetics. 30(1-2): 49-61, .
  • Wang, G.Wen, J.Wilbur, RR.Wen, P.Zhou, SF.Xiao, X. The Effect of Somatostatin, Ulinastatin and Salvia miltiorrhiza on Severe Acute Pancreatitis Treatment.The American journal of the medical sciences. (): , 2013.
  • Nabar, NR.Yuan, F.Lin, X.Wang, L.Bai, G.Mayl, J.Li, Y.Zhou, SF.Wang, J.Cai, J.Cao, C. Cell therapy: a safe and efficacious therapeutic treatment for Alzheimer's disease in APP+PS1 mice. PloS one. 7(12): e49468, 2012.
  • Mo, SL.Liu, WF.Chen, Y.Luo, HB.Sun, LB.Chen, XW.Zhou, ZW.Sneed, KB.Li, CG.Du, YM.Liang, J.Zhou, SF. Ligand- and protein-based modeling studies of the inhibitors of human cytochrome P450 2D6 and a virtual screening for potential inhibitors from the Chinese herbal medicine, Scutellaria baicalensis (Huangqin,Baikal Skullcap). Combinatorial chemistry & high throughput screening. 15(1): 36-80, 2012.
  • Yau, WP.Vathsala, A.Lou, HX.Zhou, SF.Chan, E. Simple reversed-phase liquid chromatographic assay for simultaneous quantification of free mycophenolic acid and its glucuronide metabolite in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 846(1-2): 313-8, 2007.
  • Koh, HL.Wang, H.Zhou, S.Chan, E.Woo, SO. Detection of aristolochic acid I, tetrandrine and fangchinoline in medicinal plants by high performance liquid chromatography and liquid chromatography/mass spectrometry. Journal of pharmaceutical and biomedical analysis. 40(3): 653-61, 2006.
  • Yang, XX.Hu, ZP.Duan, W.Zhu, YZ.Zhou, SF. Drug-herb interactions: eliminating toxicity with hard drug design. Current pharmaceutical design. 12(35): 4649-64, 2006.
  • Zhou, S. Clinical pharmacogenomics of thiopurine S-methyltransferase. Current clinical pharmacology. 1(1): 119-28, 2006.
  • Zhu, Y.Smith, D.Verma, C.Lim, WG.Tan, BJ.Armstrong, JS.Zhou, S.Chan, E.Tan, SL.Zhu, YZ.Cheung, NS.Duan, W. The very C-terminus of protein kinase Cepsilon is critical for the full catalytic competence but its hydrophobic motif is dispensable for the interaction with 3-phosphoinositide-dependent kinase-1.Cellular signalling. 18(6): 807-18, 2006.
  • Yang, XX.Hu, ZP.Chan, E.Duan, W.Zhou, S. Pharmacokinetics of recombinant human endostatin in rats. Current drug metabolism. 7(6): 565-76, 2006.
  • Zhang, J.Tian, Q.Zhu, YZ.Xu, AL.Zhou, SF. Reversal of resistance to oxazaphosphorines. Current cancer drug targets. 6(5): 385-407, 2006.
  • Yeong, SS.Zhu, Y.Smith, D.Verma, C.Lim, WG.Tan, BJ.Li, QT.Cheung, NS.Cai, M.Zhu, YZ.Zhou, SF.Tan, SL.Duan, W. The last 10 amino acid residues beyond the hydrophobic motif are critical for the catalytic competence and function of protein kinase Calpha. The Journal of biological chemistry. 281(41): 30768-81, 2006.
  • Yang, XX.Hu, ZP.Xu, AL.Duan, W.Zhu, YZ.Huang, M.Sheu, FS.Zhang, Q.Bian, JS.Chan, E.Li, X.Wang, JC.Zhou, SF. A mechanistic study on reduced toxicity of irinotecan by coadministered thalidomide, a tumor necrosis factor-alpha inhibitor. The Journal of pharmacology and experimental therapeutics. 319(1): 82-104, 2006.
  • Yang, XX.Hu, ZP.Chan, SY.Zhou, SF. Monitoring drug-protein interaction. Clinica chimica acta; international journal of clinical chemistry. 365(1-2): 9-29, 2006.
  • Hu, ZP.Yang, XX.Chan, SY.Xu, AL.Duan, W.Zhu, YZ.Sheu, FS.Boelsterli, UA.Chan, E.Zhang, Q.Wang, JC.Ee, PL.Koh, HL.Huang, M.Zhou, SF. St. John's wort attenuates irinotecan-induced diarrhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosis.Toxicology and applied pharmacology. 216(2): 225-37, 2006.
  • Paxton, JW.Kestell, P.Chiang, D.Zhou, S.Lewis, DF. Inhibition of human CYP1A2 oxidation of 5,6-dimethyl-xanthenone-4-acetic acid by acridines: a molecular modelling study. Clinical and experimental pharmacology & physiology. 32(8): 633-9, 2005.
  • Li, J.Zhou, S.Huynh, H.Duan, W.Chan, E. Alteration of the pharmacokinetics of COL-3, a matrix metalloproteinase inhibitor, due to acute gastrointestinal toxicity of doxorubicin. Pharmaceutical research. 22(11): 1954-63, 2005.
  • Zhou, S.Chan, E.Duan, W.Huang, M.Chen, YZ. Drug bioactivation, covalent binding to target proteins and toxicity relevance. Drug metabolism reviews. 37(1): 41-213, 2005.
  • Zhou, S.Yung Chan, S.Cher Goh, B.Chan, E.Duan, W.Huang, M.McLeod, HL. Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs.Clinical pharmacokinetics. 44(3): 279-304, 2005.
  • Zhou, S.Feng, X.Kestell, P.Paxton, JW.Baguley, BC.Chan, E. Transport of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid and its acyl glucuronide by human intestinal Caco-2 cells. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 24(5): 513-24, 2005.
  • Li, J.Zhou, S.Huynh, H.Chan, E. Significant intestinal excretion, one source of variability in pharmacokinetics of COL-3, a chemically modified tetracycline.Pharmaceutical research. 22(3): 397-404, 2005.
  • Zhou, Q.Zhou, S.Chan, E. Effect of coenzyme Q10 on warfarin hydroxylation in rat and human liver microsomes. Current drug metabolism. 6(2): 67-81, 2005.
  • Hu, Z.Yang, X.Ho, PC.Chan, SY.Heng, PW.Chan, E.Duan, W.Koh, HL.Zhou, S. Herb-drug interactions: a literature review. Drugs. 65(9): 1239-82, 2005.
  • Zhu, Y.Dong, Q.Tan, BJ.Lim, WG.Zhou, S.Duan, W. The PKCalpha-D294G mutant found in pituitary and thyroid tumors fails to transduce extracellular signals.Cancer research. 65(11): 4520-4, 2005.
  • Yang, X.Hu, Z.Chan, SY.Goh, BC.Duan, W.Chan, E.Zhou, S. Simultaneous determination of the lactone and carboxylate forms of irinotecan (CPT-11) and its active metabolite SN-38 by high-performance liquid chromatography: application to plasma pharmacokinetic studies in the rat. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 821(2): 221-8, 2005.
  • Hu, Z.Yang, X.Ho, PC.Chan, E.Chan, SY.Xu, C.Li, X.Zhu, YZ.Duan, W.Chen, X.Huang, M.Yang, H.Zhou, S. St. John's Wort modulates the toxicities and pharmacokinetics of CPT-11 (irinotecan) in rats. Pharmaceutical research. 22(6): 902-14, 2005.
  • Yang, X.Hu, Z.Chan, SY.Chan, E.Goh, BC.Duan, W.Zhou, S. Novel agents that potentially inhibit irinotecan-induced diarrhea. Current medicinal chemistry. 12(11): 1343-58, 2005.
  • Yang, X.Hu, Z.Chan, SY.Ho, PC.Chan, E.Duan, W.Goh, BC.Zhou, S. Determination of thalidomide by high performance liquid chromatography: plasma pharmacokinetic studies in the rat. Journal of pharmaceutical and biomedical analysis. 39(1-2): 299-304, 2005.
  • Zhou, S.Huang, M.Xu, A.Yang, H.Duan, W.Paxton, JW. Prediction of herb-drug metabolic interactions: a simulation study. Phytotherapy research : PTR. 19(6): 464-71, 2005.
  • Tian, Q.Zhang, J.Tan, TM.Chan, E.Duan, W.Chan, SY.Boelsterli, UA.Ho, PC.Yang, H.Bian, JS.Huang, M.Zhu, YZ.Xiong, W.Li, X.Zhou, S. Human multidrug resistance associated protein 4 confers resistance to camptothecins. Pharmaceutical research. 22(11): 1837-53, 2005.
  • Zhang, J.Tian, Q.Chan, SY.Duan, W.Zhou, S. Insights into oxazaphosphorine resistance and possible approaches to its circumvention. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy. 8(5): 271-97, 2005.
  • Zhou, Q.Zhou, S.Chan, E. Effect of omeprazole on the hydroxylation of warfarin enantiomers in human: in-vitro studies with liver microsomes and cDNA-expressed cytochrome P450 isozymes. Current drug metabolism. 6(5): 399-411, 2005.
  • Zhang, J.Tian, Q.Yung Chan, S.Chuen Li, S.Zhou, S.Duan, W.Zhu, YZ. Metabolism and transport of oxazaphosphorines and the clinical implications. Drug metabolism reviews. 37(4): 611-703, 2005.
  • Zhou, S.Lim, LY.Chowbay, B. Herbal modulation of P-glycoprotein. Drug metabolism reviews. 36(1): 57-104, 2004.
  • Zhou, S.Koh, HL.Gao, Y.Gong, ZY.Lee, EJ. Herbal bioactivation: the good, the bad and the ugly. Life sciences. 74(8): 935-68, 2004.
  • Zhou, S.Chan, E.Pan, SQ.Huang, M.Lee, EJ. Pharmacokinetic interactions of drugs with St John's wort. Journal of psychopharmacology (Oxford, England). 18(2): 262-76, 2004.
  • Zhou, S.Feng, X.Kestell, P.Baguley, BC.Paxton, JW. Determination of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid and its acyl glucuronide in Caco-2 monolayers by liquid chromatography with fluorescence detection: application to transport studies. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 809(1): 87-97, 2004.
  • Zhou, S.Chan, E.Li, SC.Huang, M.Chen, X.Li, X.Zhang, Q.Paxton, JW. Predicting pharmacokinetic herb-drug interactions. Drug metabolism and drug interactions. 20(3): 143-58, 2004.
  • Zhou, S.Chan, E.Lim, LY.Boelsterli, UA.Li, SC.Wang, J.Zhang, Q.Huang, M.Xu, A. Therapeutic drugs that behave as mechanism-based inhibitors of cytochrome P450 3A4. Current drug metabolism. 5(5): 415-42, 2004.
  • Zhou, S.Li, Y.Kestell, P.Paxton, JW. Determination of thalidomide in transport buffer for Caco-2 cell monolayers by high-performance liquid chromatography with ultraviolet detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 785(1): 165-73, 2003.
  • Zhou, S.Gao, Y.Jiang, W.Huang, M.Xu, A.Paxton, JW. Interactions of herbs with cytochrome P450. Drug metabolism reviews. 35(1): 35-98, 2003.
  • Zhou, S. Separation and detection methods for covalent drug-protein adducts. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 797(1-2): 63-90, 2003.
  • Zhou, S.Kestell, P.Baguley, BC.Paxton, JW. Preclinical factors influencing the relative contributions of Phase I and II enzymes to the metabolism of the experimental anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid. Biochemical pharmacology. 65(1): 109-20, 2003.
  • Zhou, S.Kestell, P.Baguley, BC.Paxton, JW. Preclinical factors affecting the interindividual variability in the clearance of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid. Biochemical pharmacology. 65(11): 1853-65, 2003.
  • Zhou, S.Kestell, P.Paxton, JW. Non-specific binding of the experimental anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in liver microsomes from various species. The Journal of pharmacy and pharmacology. 54(7): 997-1003, 2002.
  • Zhou, S.Kestell, P.Paxton, JW. Strain differences in the liver microsomal metabolism of the experimental anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid in mice. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 776(2): 231-6, 2002.
  • Zhou, S.Kestell, P.Paxton, JW. Predicting pharmacokinetics and drug interactions in patients from in vitro and in vivo models: the experience with 5,6-dimethylxanthenone-4-acetic acid (DMXAA), an anti-cancer drug eliminated mainly by conjugation. Drug metabolism reviews. 34(4): 751-90, 2002.
  • Zhou, S.Kestell, P.Tingle, MD.Paxton, JW. Thalidomide in cancer treatment: a potential role in the elderly? Drugs & aging. 19(2): 85-100, 2002.
  • Zhou, S.Chin, R.Kestell, P.Tingle, MD.Paxton, JW. Effects of anticancer drugs on the metabolism of the anticancer drug 5,6-dimethylxanthenone-4-acetic (DMXAA) by human liver microsomes. British journal of clinical pharmacology. 52(2): 129-36, 2001.
  • Zhou, S.Kestell, P.Tingle, MD.Ching, LM.Paxton, JW. A difference between the rat and mouse in the pharmacokinetic interaction of 5,6-dimethylxanthenone-4-acetic acid with thalidomide. Cancer chemotherapy and pharmacology. 47(6): 541-4, 2001.
  • Zhou, S.Paxton, JW.Tingle, MD.Kestell, P. Identification of the human liver cytochrome P450 isoenzyme responsible for the 6-methylhydroxylation of the novel anticancer drug 5,6-dimethylxanthenone-4-acetic acid. Drug metabolism and disposition: the biological fate of chemicals. 28(12): 1449-56, 2000.



  •  

    Shufeng Zhou

    Professor

     

    • : 813 9746276
      Fax: 813 9059885

    • DEPARTMENT

      Department of Molecular Medicine University of South Florida

       

    • COUNTRY USA