Publications

• Kaur G, Rapthap CC, Xavier M, Saxena R, Choudhary VP, Reuben SK, Mehra K. “Distribution of C282Y and H63D mutations in the HFE gene in healthy Asian Indians and patients with thalassaemia major”. Natl Med J India ;16(6):309-10. 2003. PubMed ID:14765621
• Doss MX, Koehler CI, Gissel C, Hescheler J, Sachinidis A. “Embryonic stem cells: a promising tool for cell replacement therapy”. Journal of Cellular and Molecular Medicine;8(4):465-73, 2004 PUBMED ID: 15601575
• Gissel C, Voolstra C, Doss MX, Koehler CI, Winkler J, Hescheler J, Sachinidis A. “An optimized embryonic stem cell model for consistent gene expression and developmental studies: a fundamental study”. Thrombosis and Haemostosis;94(4):719-27, 2005PUBMED ID: 16270623
• Potta SP, Doss MX, Hescheler J and Sachinidis A. “Epigallocatechin-3-Gallate (EGCG): A Structural Target for the Development of Potential Therapeutic Drugs Against Anti- Proliferative Diseases”. Drug Design Reviews, 2005:2:1:85-91
• Doss MX, Potta SP, Hescheler J, Sachinidis A. “Trapping of growth factors by catechins: a possible therapeutical target for prevention of proliferative diseases”. Journal of Nutritional Biochemistry;16(5):259-66, 2005. PUBMED ID: 15866224
• Gissel C, Doss MX, Hippler-Altenburg R, Hescheler J, Sachinidis A. “Generation and characterization of cardiomyocytes under serum-free conditions”. Methods in Molecular Biology;330:191-219, 2006 PUBMED ID: 16846026
• Mariappan D, Winkler J, Parthiban V, Doss MX, Hescheler J, Sachinidis A. Dietary small molecules and large-scale gene expression studies: an experimental approach for understanding their beneficial effects on the development of malignant and non-malignant proliferative diseases. Curr Med Chem. 13(13):1481-9. 2006 PUBMED ID: 16787199
• Doss MX, Winkler J, Chen S, Hippler-Altenburg R, Sotiriadou I, Halbach M, Pfannkuche K,Liang H, Schulz H, Hummel O, Hübner N, Rottscheidt R, Hescheler J, Sachinidis A “Global transcriptome analysis of murine embryonic stem cells derived cardiomyocytes.” Genome Biolog;8(4):R56, 2007 PUBMED ID: 17428332
• Doss MX, Chen S, Winkler J, Hippler-Altenburg R, Odenthal M, Wickenhauser C, Balaraman S, Schulz H, Hummel O, Hübner N, Ghosh-Choudhury N, Sotiriadou I, Hescheler J, Sachinidis A. “Transcriptomic and phenotypic analysis of embryonic stem cell derived BMP2+ lineage cells: an insight into mesodermal patterning” Genome Biology; 8(9):R184, 2007 PUBMED ID: 17784959
• Doss MX, Sachinidis A, and Hescheler J “Human ES Cell Derived Cardiomyocytes for Cell Replacement Therapy: A Current Update” Chinese Journal of Physiology 51(4): 1-4, 2008 PUBMED ID: 19112880
• Pfannkuche K, Wunderlich FT, Doss MX, Spitkovsky D, Reppel M, Sachinidis A, Hescheler J. “Generation of a double-fluorescent double-selectable Cre/loxP indicator vector for monitoring of intracellular recombination events.” Nat Protoc.;3(9):1510-26, 2008 PUBMED ID: 18772879
• Akasha AA, Sotiriadou I, Doss MX, Halbach M, Winkler J, Baunach JJ, Katsen-Globa A, Zimmermann H, Choo Y, Hescheler J, Sachinidis A.” Entrapment of embryonic stem cellsderived cardiomyocytes in macroporous biodegradable microspheres: preparation and characterization” Cell Physiol Biochem.;22(5-6):665-72, 2008 PUBMED ID: 19088448
• Potta SP, Liang H, Pfannkuche K, Winkler J, Chen S, Doss MX, Obernier K, Kamisetti K, Schulz H, Hescheler J and Sachinidis A “Functional characterization and global transcriptome analysis of contractile smooth muscles cells derived from a murine transgenic Acta2 embryonic stem cell lineage” Hypertension;53(2):196-204, 2009 PUBMED ID: 19064816
• Trouillas M, Saucourt C, Guillotin B, Gauthereau X, Ding L, Buchholz F, Doss MX, Sachinidis A, Hescheler J, Hummel O, Hubner N, Kolde R, Vilo J, Schulz H and Boeuf H “Three LIF-dependent signatures and “competency genes” identified by gene profiling studies in mouse ES cells and early derivatives” BMC Genomics:10:73, 2009 PUBMED ID: 19203379
• Ding L, Paszkowski-Rogacz M, Nitzsche A, Slabicki MM, Heninger AK, Vries ID, Kittler R, Junqueira M, Shevchenko A, Schulz H, Hubner N, Doss MX, Sachinidis A, Hescheler J, Iacone R, Anastassiadis K, Stewart AF, Pisabarro MT, Caldarelli A, Poser I, Theis M, Buchholz F. “A Genome-Scale RNAi Screen for Oct4 Modulators Defines a Role of the Paf1 Complex for Embryonic Stem Cell Identity” Cell Stem Cell.:4(5):403-15, 2009 PUBMED ID: 19345177
• Schulz H, Kolde R, Adler P, Aksoy I, Anastassiadis K, Bader M, Billon N, Boeuf H, Bourillot PY, Buchholz F, Dani C, Doss MX, Forrester L, Gitton M, Henrique D, Hescheler J, Himmelbauer H, Hübner N, Karantzali E, Kretsovali A, Lubitz S, Pradier L, Rai M, Reimand J, Rolletschek A, Sachinidis A, Savatier P, Stewart F, Storm MP, Trouillas M, Vilo J, Welham MJ, Winkler J, Wobus AM, Hatzopoulos AK; Functional Genomics in Embryonic Stem Cells Consortium. "The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation".PLoS One. 2009 Sep 3;4(9):e6804. PUBMED ID: 19727443
• Gunaseeli I, Doss MX, Antzelevitch C, Hescheler J, Sachinidis A "Induced Pluripotent Stem (iPS) Cells as a Model for Accelerated Drug Discovery". Curr Med Chem. 2010 Jan 21. [Epub ahead of print] PUBMED: 20088756
• Potta SP, Liang H, Winkler J, Doss MX, Chen S, Wagh V, Pfannkuche K, Hescheler J, Sachinidis A. “Isolation and functional characterization of alpha-smooth muscle actin expressing cardiomyocytes from embryonic stem cells” Cell Physiol Biochem. 2010; 25(6):595-604. PUBMED ID:20511704
• Doss MX, Wagh V, Schulz H, Kull M, Kolde R, Pfannkuche K, Nolden T, Himmelbauer H, Vilo J, Hescheler J, Sachinidis A: “Global Transcriptomic Analysis of Murine ESC Derived Brachyury+ (T) Cells” Genes to Cells” 2010; 15:3:209 – 228. PUBMED ID:20184659
• Brown K, Legros S, Artus J, Doss MX, Khanin R, Hadjantonakis AK, Foley A. A comparative analysis of extra-embryonic endoderm cell lines. PLoS One, 2010 Aug 6;5(8):e12016. PubMed ID: 20711519
• Brown K, Doss MX, Legros S, Artus J, Hadjantonakis AK, Foley AC. eXtraembryonic ENdoderm (XEN) stem cells produce factors that activate heart formation. PLoS One, 2010 Oct 20;5(10):e13446. PubMed ID: 20975998
• Conesa C, Doss MX, Antzelevitch C, Sachinidis A, Sancho J, Carrodeguas JA. Identification of Specific Pluripotent Stem Cell Death-inducing Small Molecules by Chemical Screening. Stem Cell Reviews and Reports, 2012 Mar;8(1):116-27. PubMed ID: 21617963
• Doss MX, Gaspar A, Hescheler J, Winkler J, Schulz H, Sachinidis A, “Specific gene signatures and pathways in mesodermal cells and their derivatives derived from embryonic stem cells. Stem Cell Reviews and Reports, 2012 Mar;8(1):43-54 PUBMED ID:21519850
• Gaspar JA, Doss MX, Winkler J, Wagh V, Kolde R, Vilo J, Hescheler J, Schulz H, Sachinidis A. Gene expression signatures defining fundamental biological processes in pluripotent, early and the late differentiated embryonic stem cells. Stem Cells Dev. 2012 Apr 17. [Epub ahead of print] PubMed ID: 22420508
• Doss MX, Di Diego JM, Goodrow R, Wu Y, Barajas-Martínez H, Hu D, Urrutia J, Cordeiro JM, Nesterenko VV, Desai M, Treat J, Sachinidis A, Antzelevitch C. Maximum diastolic potential of human induced pluripotent stem cell-derived cardiomyocyte depends critically on IKr. PLoS ONE, 2012;7(7):e40288. Epub 2012 Jul 5. PubMed ID: 22815737
• Cordeiro JM, Nesterenko VV, Sicouri S, Goodrow RJ Jr, Treat JA, Doss MX, Antzelevitch C, Di Diego JM. Identification and characterization of a transient outward K+ current in human induced pluirpotent stem cell-derived cardiomyocytes. J Mol Cell Cardiol, 2013;60:36-46. PubMed ID: 3779808
• Burashnikov A, Di Diego JM, Sicouri S, Doss MX, Sachinidis A, Barajas-Martínez H, Hu D, Minoura Y, Moise NS, Kornreich BG, Chi L, Belardinelli L, Antzelevitch C. A temporal window of vulnerability for development of atrial fibrillation with advancing heart failure. Eur J Heart Fail, 16:271-280, 2014. PubMed ID:24464846
• Gaspar JA, Doss MX, Cadenas C, Hengstler J. Hescheler J, Sachinidis A. Unique metabolic features of stem cells, cardiomyocytes and their stem cell progenitors. Circulation Research, 2014 Apr 11;114(8):1346-60.  equally contributed . PubMed ID:24723659
• Aksoy I, Giudice V, Delahaye E, Wianny F, Aubry M, Mure M, Jiaxuan, Jauch R, Bogu G, Nolden T, Himmelbauer H, Doss MX, Sachinidis A, Schulz H, Hummel O, Martinelli P, Hubner N, Stanton L, Real F, Bourillot PY, Savatier P. Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells. Nature Communications, 2014 Apr 28;5:3719. PubMed ID: 24770696
• Wagh V, Doss MX, Sabour D, Niemann R, Meganathan K, Jagtap S, Gaspar JA, Ardestani MA, Papadopoulos S, Gajewski M, Hescheler J, Sachinidis A. Fam40b is required for early and late lineage commitment of murine embryonic stem cells. Cell Death Differ, in press, 2014.

Book Chapter:

• Šaric T, Chen S, Kamisseti N, Halbach M, Doss MX, Winkler J, Hescheler J and Sachinidis A “Embryonic Stem Cells and Their Therapeutic Potential” 2008 "Handbook of Cardiac Stem Cell Therapy" (edited by Ioannis Dimarakis et al.) (http://www.worldscibooks.com/lifesci/p582.html) 2008.
  
• Doss MX, Antzelevitch C, Sachinidis A., “Human Induced Pluripotent Stem Cells: Role In Patient-Specific Drug Discovery” Stem Cells and Cancer Stem Cells: Therapeutic Applications in Disease and Injury, Volume 3, Springer, edited by M.A. Hayat, 2012. http://link.springer.com/chapter/10.1007/978-94-007-2415-0_26