Publications

Peer-reviewed Publications

• Vanguri VK, Shuxia Wang, Svetlana Godyna, Spriya Ranganathan and Gene Liau (2000). Thrombospondin-1 binds to polyhistidine with high affinity and specificity. Biochem J. 347, 469-473. PM ID: 10749676
• Shuxia Wang, Sruti Shiva, Maria H. Poczatek, Victor Darley-Usmar, and Joanne E. Murphy-Ullrich (2002). Nitric oxide and cGMP-dependent protein kinase regulation of thrombospondin 1-dependent TGF-â activation in response to high glucose exposure. J Biol Chem. 277(12), 9880-8. PMID: 11784717
• Shuxia Wang, Xing Wu, Thomas M. Lincoln and Joanne E. Murphy-Ullrich (2003). Expression of constitutively active cGMP-dependent protein kinase prevents glucose-induced thrombospondin1 expression and TGF-beta activation. Diabetes. 52 (8), 2144-2150. PMID: 12882943
• Shuxia Wang*, Xu Feng and Joanne Murphy-Ullrich (2004). Glucose upregulates thrombospondin1 gene transcription and transforming growth factor-beta activity through antagonism of cGMP-dependent protein kinase repression via upstream stimulatory factor 2. J Biol Chem 279 (33), 3431 1-34322, PMID: 15184388
• Shuxia Wang, Mary E. Herndon, Sripriya Ranganathan, Svetlana Godyna, Jack Lawler, W. Scott Argraves and Gene Liau (2004). Internalization but not binding of thrombospondin 1 to low density lipoprotein receptor-related protein-1 (LRP1) requires heparin sulfate proteoglycans. J Cell Biochem 91, 766-776, PMID:14991 768
• Liu Shu, Xueying Ma, Lihua Shi, Thomas Lincoln and Shuxia Wang (2007). Glucose down-regulation of cGMP-dependent protein kinase-I expression in vascular smooth muscle cells involves NADPH oxidase-derived reactive oxygen species. Free Radical Biology and Medicine, 42(6), 852-63, PM ID: 17320767
• Shuxia Wang*, Thomas Lincoln, and Joanne Murphy-Ullrich (2010). Thrombondin1 mediates glucose stimulation of TGF-beta bioactivity in vascular smooth muscle cells. Am J Physiol Cell Physiol, 298 (5), C1188-97, PMID: 20164378
• Yanzhang Li and Shuxia Wang (2010). Glycated albumin activates NADPH oxidase in rat mesangial cells through up-regulation of p47phox. Biochemical and Biophysical Research Communication, 397 (1), 5-11, PMID: 20399741
• Yanzhang Li, Xiaopeng Tong, Courtney Rumala, Kate Clemons, and Shuxia Wang (2011).Thrombospondin1 deficiency reduces obesity-associated inflammation and imporves insulin sensitivity in a diet-induced obese mouse model. PLoS One,6 (10), e26656. PMID: 22039525
• Dejan Nikolic, Shu Liu, Yanzhang Li, and Shuxia Wang *(2011). Over-expression of constitutively active PKG-I protects female, but not male mice from diet-induced obesity. Obesity, 19 (4), 784-91, PMID: 20930715
• Shuxia Wang (2012). Thrombospondin1 plays an important role in obesity induced inflammation and insulin resistance. Journal of Obesity & Weight Loss Therapy, 2(9), 1000e109, ISSN:2165-7904
• Yanzhang Li, Xinyu Qi, Xiaopeng Tong, and Shuxia Wang. (2013). Thrombospondin 1 activates the macrophage Toll-like receptor 4 pathway. Cell Mol Immunol, Aug. 19 [Epub ahead of print]. PMID: 23954950
• Wenpeng Cui, Hasiyeti Maimaitiyiming, Xinyu Qi, Heather Norman, and Shuxia Wang. (2013). Thrombospondin1 mediates renal dysfunction in a mouse model of high fat diet-induced obesity. Am J Physiol-Renal Physiol, 305(6), F871-880. PMID: 23863467
• Hasiyeti Maimaitiyiming, Yanzhang Li, Wenpeng Cui, Xiaopeng Tong, Heather Norman, Xinyu Qi, and Shuxia Wang (2013). Increasing cGMP-dependent protein kinase I activity attenuates cisplatin induced acute kidney injury. Am J of Physiol-renal, 2013, July 3
• Wenpeng Cui, Hasiyeti Maimaiting, Xinyu Qi, Heather Norman, Qi Zhou, Xiaojun Wang, Jian Fu, and Shuxia Wang (2014). Increasing cGMP-dependent protein kinase activity attenuates unilateral ureteral obstruction-induced renal fibrosis. Am J of Physiol-renal, Feb 26, Epub ahead of print.