Publications

Bibliography

Dr. Ghosh Choudhury is cited in PubMed as ‘Ghosh Choudhury G’ and ‘Choudhury GG’

  • Papers published in Peer Reviewed Journals (# 54 publication was listed in “Top 100 Cell Cycle papers in 2006”) (#34 paper  was  quoted  and summarized in Breast Cancer News (BCN) Oct 23, 2009 issue) (#30 paper was selected in the list of “20 Popular publications for March 2010 in the category of Free Radicals)
    1. Das F., Ghosh-Choudhury N., Dey N., Bera A., Mariappan  M.  M.,  Kasinath  B.  S.  and Ghosh Choudhury G. High glucose forces a positive feed back loop connecting Akt kinase and FoxO1 to activate mTORC1 for mesangial cell hypertrophy and matrix protein expression. J Biol Chem, In Press.
    2. Das F., Bera A., Ghosh-Choudhury N., Abboud H. E., Kasinath B. S. and Ghosh Choudhury G. TGFβ-induced deptor suppression recruits mTORC1 and not mTORC2 to enhance collagen I (α2) gene expression. PLoS One In Press, 2014.
    3. Bera A., Das F., Ghosh-Choudhury N., Li X., Pal S., Gorin Y., Kasinath B. S., Abboud H. E and Ghosh Choudhury G. A positive feedback loop involving Erk5 and Akt turns on mesangial cell proliferation in response to PDGF. Am J Physiol Cell Physiol 306: C1089 – C1100, 2014.
    4. Bera A., Das F., Ghosh-Choudhury N., Kasinath B. S., Abboud H. E. and Ghosh Choudhury G. microRNA-21-induced dissociation of PDCD4 from rictor contributes to Akt- IKKβ-mTORC1 axis to regulate renal cancer cell invasion. Exp Cell Res In Press, 2014.
    5. Mariappan M. M., Dsilva K., Sorice G., Muscogiuri G., Jimenez F., Ahuja S., Barnes J. L., Ghosh Choudhury G., Musi N., Defronzo R. and Kasinath B. S. Combined acute hyperglycemic and hyperinsulinemic clamp induced profibrotic and proinflammatory responses in the kidney. Am J Physiol Cell Physiol. 306: C202-C211, 2014.
    6. Bera A., Ghosh-Choudhury N., Dey N., Das F., Kasinath B. S., Abboud H. E. and Ghosh Choudhury G. NFκB-mediated cyclin D1 expression by microRNA-21 influences  renal cancer cell proliferation. Cell Signal. 25: 2575-2586, 2013
    7. Ghosh-Choudhury N., Mandal C. C., Das F., Ganapathy S., Ahuja S. and Ghosh Choudhury G.c-Abl-dependent          molecular circuitry involving Smad5 and phosphatidylinositol  3-kinase  regulates  bone  morphogenetic  protein-2-induced osteogenesis. J Biol Chem 288: 24503 - 24517, 2013.
    8. Das F, Ghosh-Choudhury N., Bera A., Dey N., Abboud H. E., Kasinath B. S. and Ghosh Choudhury G. TGFβ integrates Smad 3 to mechanistic target of rapamycin complexes to arrest deptor abundance for glomerular mesangial cell hypertrophy. J Biol Chem 288: 7756 -7768, 2013.
    9. Lee D-Y., Wauquier F and Eid A. A., Roman L .J., Ghosh Choudhury G., Khazim K., Block K. and Gorin Y. Nox4 NADPH oxidase mediates peroxynitrite-dependent uncoupling of endothelia nitric oxide synthase and fibronectin expression in response to angiotensin II. Role of mitochorndrial reactive oxygen species. J Biol Chem 288: 28668-28686, 2013.
    10. Das F., Ghosh-Choudhury N., Bera A., Kasinath B. S. and Ghosh Choudhury G. TGFβ- induced PI 3 kinase-dependent Mnk-1 activation is necessary for Ser-209 phosphorylation of eIF4E and mesangial cell hypertrophy. J Cell Physiol 228: 1617-1626, 2013.
    11. Eid A. A., Ford B. M., Bhandary B., Cavagliery R., Block K., Barnes J. L., Gorin Y., Ghosh Choudhury G. and Abboud H. E. mTOR regulates Nox4-mediated podocyte depletion in diabetic renal injury. Diabetes. 62: 2935 -2947, 2013.
    12. Dey N., Ghosh-Choudhury N., Kasinath B. S. and Ghosh Choudhury G. TGFβ-stimulated microRNA-21 utilize PTEN to orchestrate Akt/mTORC1 signaling for  mesangial  cell hypertrophy and matrix expansion. PLOS One, 7: e42316, 2012.
    13. Mandal C. C., Ghosh-Choudhury T., Dey N., Ghosh Choudhury G. and Ghosh-Choudhury N. miR-21 is targeted by omega-3 polyunsaturated fatty acid to regulate breast tumor CSF- 1 expression. Carcinogenesis 33: 1897-1908, 2012.
    14. Sataranatarajan K., Feliers D., Mariappan M. M., Lee H. J., Lee M. J., Day R. T., Yelamanchili H, Ghosh Choudhury G., Barnes J. L., Van Rammen J., Richardson A. and Kasinath B. S. Molecular events in matrix protein metabolism in the aging kidney. Aging Cell. 11: 1065-1073, 2012.
    15. Dey N., Das F., Ghosh-Choudhury N., Mandal C. C., Parekh D. J., Block K., Kasinath B. S., Abboud H. E. and Ghosh Choudhury G. microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion. PLOS One, 6: e37366, 2012.
    16. Das F., Ghosh-Choudhury N., Dey N., Mandal C. C., Mahimainathan L., Kasinath B. S., Abboud H. E. and Ghosh Choudhury G. Unrestrained mammalian target of rapamycin complexes 1 and 2 increase expression of phosphatase and tensin homolog deleted on chromosome 10 to regulate phosphorylation of Akt kinase. J Biol chem. 287: 3803-3822, 2012.
    17. Lee H. J., Mariappan M. M., Feliers D., Cavaglieri R. C., Sataranatarajan K., Abboud H. E., Ghosh Choudhury  G and Kasinath B. S. Hydrogen  sulfide  inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells. J Biol Chem 287: 4451-4461, 2012.
    18. Tabatabai-Mir H., Sataranatarajan K., Lee H. J., Bokov A. F., Fernandez E., Diaz V., Ghosh Choudhury G., Richardson A. and Kasinath B. S. Rapamycin selectivity alters serum chemistry in diabetic mice. Pathobiology of Aging-related Diseases 2: 15896 – http://dx.doi.org/10.3402/pba.v210.15896.   2012.
    19. Saldarriaga O. A., Travi B. L., Ghosh Choudhury G and Melby P.  C.  Identification  of hamster inducible nitric oxide synthase  (iNOS)  promoter  sequences  that  influence  basal and inducible iNOS expression. J Leukoc Biol 92: 205-218, 2012.
    20. Dey N., Das F., Mariappan M. M., Mandal C. C., Ghosh Choudhury N., Kasinath B. S. and Ghosh Choudhury G. microRNAs-21 orchestrates high glucose-induced signals to TORC1 for renal cell pathology in diabetes. J Biol Chem 286: 25586-255603, 2011.
    21. Das F., Dey N., Venkatesan B., Kasinath B. S., Ghosh-Choudhury N. and Ghosh Choudhury G. High glucose upregulation of early-onset Parkinson’s disease protein DJ-1 integrates the PRAS40/TORC1 axis in mesangial cell hypertrophy. Cell Signal 23: 1311- 1319, 2011.
    22. Mandal C. C., Ghosh-Choudhury N., Yoneda T., Ghosh Choudhury G. and Ghosh- Choudhury N. Simvastatin prevents skeletal metastasis of breast cancer by an antagonistic interplay between p53 and CD44. J Biol Chem 286: 11314-11327, 2011.
    23. Mariappan M. M., D’Silva K., Lee M. J., Sataranatarajan K., Barnes J. L., Ghosh Choudhury G. and Kasinath B. S. Ribosomal biogenesis induction by high glucose requires activation of upstream binding factor in kidney glomerular  epithelial  cells.  Am  J  Physiol Renal Physiol 300: F219-F230, 2011.
    24. Mandal C. C., Ganapathy S., Gorin Y., Mahadev K., Block K., Abboud H. E., Harris S. E., Ghosh Choudhury G. and Ghosh-Choudhury N. Reactive oxygen species derived Nox4 mediate BMP-2 gene transcription and osteoblast differentiation. Biochem J 433: 393-402, 2011.
    25. Dey N., Ghosh-Choudhury N., Das F., Li X., Venkatesan B., Barnes J. L., Kasinath B. S. and Ghosh Choudhury G. PRAS40 acts as a nodal regulator of  high  glucose-induced TORC1 activation glomerular mesangial cell hypertrophy. J Cell Physiol 225: 27-41, 2010
    26. Das F., Ghosh-Choudhury N., Kasinath B. S. and Ghosh Choudhury G. TGFβ enforces activation of eukaryotic elongation factor-2 (eEF2) via inactivation of eEF2 kinase by p90 ribosomal S6 kinase (p90Rsk) to induce mesangial cell hypertrophy. FEBS Lett 584: 4268- 4272, 2010.
    27. Ghosh-Choudhury N., Mandal C. C., Ghosh-Choudhry N. and Ghosh Choudhury G. Simvastatin induces derepression of PTEN expression via NFkappaB to inhibit  breast cancer cell growth. Cell Signal 22: 749-758, 2010.
    28. Eid A. A., Ford B. M., Block K., Kasinath B. S., Gorin Y., Ghosh Choudhury G., Barnes J. L. and Abboud H. E. AMP-activated protein kinase (AMPK) negatively regulates Nox4- dependent activation of p53 and epithelial cells apoptosis in diabetes. J Biol Chem 285: 37503-37512, 2010.
    29. Mandal C. C., Ghosh-Choudhury T., Yoneda T., Ghosh Choudhury G. and Ghosh- Choudhury N. Fish oil prevents breast cancer cell metastasis to bone. Biochem Biophys Res Commun 402: 802-807, 2010
    30. Block K., Gorin Y., New D. D., Eid A., Chelmicki T., Reed A., Ghosh Choudhury G., Parekh D. J. and Abboud H. E. The NADPH oxidase subunit p22pox inhibits the function of the tumor suppressor protein tuberin. Am J Pathol 176: 2447-2455, 2010.
    31. Mandal C. C., Drissi H., Ghosh Choudhury G. and Ghosh Choudhury N. Integration of phosphatidylinositol 3-kinase, Akt kinase, and Smad signaling pathway in BMP-2-induced osterix expression. Calcif Tissue Int 87: 533-540, 2010.
    32. Lee M-J., Feliers D., Sataranatarajan K., Mariappan M. M., Barnes J. L., Ghosh Choudhury G. and Kasinath B. S. Resveratrol ameliorates high glucose-induced protein synthesis in glomerular epithelial cells. Cell Signal, 22: 65-70, 2010.
    33. Mahimainathan L., Ghosh-Choudhury N., Venkatesan B., Das F., Mandal C. C., Dey N., Habib S. L., Kasinath B. S., Abboud H. E. and Ghosh Choudhury G. TSC2  deficiency increases PTEN via HIF1α. J Biol Chem 284: 27790-27798, 2009.
    34. Ghosh-Choudhury T., Mandal C. C., Woodruff K., St Clair P., Fernandes G., Ghosh Choudhury G. and Ghosh-Choudhury N. Fish oil targets PTEN to regulate NFκB for downregulation of anti-apoptotic genes in breast tumor growth. Breast Cancer Res Treatment, 118: 213-228, 2009.
    35. Mandal C. C., Ghosh Choudhury G. and Ghosh-Choudhury N. Phosphatidylinositol 3 kinase/Akt signal relay cooperates with Smad in bone morphogenetic  protein-2-induced colony stimulating factor-1 expression and osteoclast differentiation. Endocrinology, 150: 4989-4998, 2009.
    36. Ricono J. M., Wagner B., Gorin Y., Arar M., Kazlauskas A.,  Ghosh  Choudhury  G.  and Abboud J. E. PDGF receptor beta negatively regulates PDGF AA-induced migration of metanephric mesenchymal cells. Am J Physiol Renal Physiol 296: F406-F417, 2009.
    37. Venkatesan B., Ghosh-Choudhury N., Das F., Mahimainathan L., Kamat A., Kasinath B. S., Abboud H. E. and Ghosh Choudhury G. Resveratrol inhibits PDGF receptor mitogenic signaling in mesangial cells: role of PTP1B. FASEB J. 22: 3469-3482, 2008.
    38. Mariappan M. M., Shetty M, Sataranatarajan K., Ghosh Choudhury G. and Kasinath B. S. GSK3β is a novel regulator of high glucose- and high insulin-induced extracellular matrix protein synthesis in renal proximal tubular epithelial cells. J Biol Chem. 283: 30566-30575, 2008.
    39. Kamat A., Ghosh P. M., Glover R. L., Zhu B., Yeh C-K., Ghosh Choudhury G. and Katz M.S. Reduced expression of epidermal growth factor receptors in rat liver during aging. J. Gerontolgy. J Gerontol A Biol Sci Med Sci 63: 683-692, 2008.
    40. Das F., Ghosh-Choudhury N., Venkatesan B., Li X., Mahimainathan L., Ghosh Choudhury Akt  kinase  targets  association  of  CBP  with  Smad  3  to  regulate  TGFβ-induced expression of plasminogen activator inhibitor-1. J Cell Physiol. 214: 513-527, 2008.
    41. Das F., Ghosh-Choudhury N., Mahimainathan L., Venkatesan B., Feliers D., Riley D. J., Kasinath B. S. and Ghosh Choudhury G. Raptor-Rictor axis in TGFβ-induced protein synthesis. Cell Signal. 20: 409-423, 2008.
    42. Habib S. L., Riley D. J., Mahimainathan L., Bhandari B., Ghosh Choudhury G. and Abboud E. Tuberin regulates the DNA repair enzyme OGG1. Am J Physiol Renal Physiol 294: F281-F290, 2008.
    43. Quinones M. P., Kalkonde Y., Estrada C. A., Jimenez F., Ramirez R., Mahimainathan L., Mummidi S., Ghosh Choudhury G., Martinez H., Adams L., Mack M., Reddick R. L., Maffi S., Haralambous S., Probert L., Ahuja S. K. and Ajuha S. S. Role of astrocytes and chemokine system in acute TGFα induced demyelinating syndrome: CCR2-dependent signals promote astrocyte activation and survival via NF-κB and Akt. Mol Cell Neurosci. 37: 96-109, 2008.
    44. Das F., Mahimainathan L., Ghosh-Choudhury N., Venkatesan B., Kasinath B. S., Abboud H. E. and Ghosh Choudhury G. TGFβ intercepts nuclear glycogen synthase kinase3β to inhibit PDGF-induced DNA synthesis in mesangial  cells.  FEBS Letters. 581:  5259-5267, 2007.
    45. Ghosh-Choudhury N., Mandal C. C. and Ghosh Choudhury G. Statin-induced Ras activation integrates PI 3 kinase signal to Akt and MAPK for BMP-2 expression in osteoblast differentiation. J Biol Chem, 282: 4983-4993, 2007.
    46. Venkatesan B., Mahimainathan L, Das F., Ghosh-Choudhury N and Ghosh Choudhury G. Downregulation of catalase by reactive oxygen species via PI 3 kinase/Akt signaling in mesangial cells. J Cell Physiol 211: 457-467, 2007.
    47. Sataranatarajan K., Mariappan M. M., Lee M-J., Feliers D., Ghosh Choudhury G., Barnes J.L. and Kasinath B. S. Mechanism of rapamycin-induced amelioration of kidney disease in mice with type 2 diabetes. Am J Pathol. 171: 1733-1742, 2007.
    48. Wagner B., Ricono J. M., Gorin Y., Block K., Arar M., Riley D., Ghosh Choudhury G. and Abboud H. E. Mitogenic signaling via platelet-derived growth factor beta in metanephric mesenchymal cells. J Am Soc Nephrol 18: 2903-2911, 2007.
    49. Feliers D., Lee MJ, Ghosh Choudhury G., Bomsztyk K. and Kasinath B. S. Heterogeneous nuclear ribonucleoprotein K contributes to angiotensin II stimulation of vascular endothelial growth factor mRNA translation. Am J Physiol Renal Physiol. 293: F607-F615, 2007.
    50. Lee M. J., Feliers D., Mariappan M. M., Sataranatarajan K., Mahimainathan L, Musi N., Foretz M., Viollet B., Weinberg J. M., Ghosh Choudhury G. and Kasinath B. S. A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy. Am J Physiol Renal Physiol 292: F617-F627, 2007.
    51. Mariappan M. M., Feliers D., Mummidi S., Ghosh Choudhury G. and Kasinath B. S. High glucose, high insulin and their combination rapidly induce laminb1 synthesis by regulation of mRNA translation in renal epithelial cells. Diabetes, 56: 476-485, 2007.
    52. Mahimainathan L, Das F., Venkatesan B. and Ghosh Choudhury G. Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTEN. Diabetes 55: 2115-2125, 2006.
    53. Ghosh-Choudhury N., Singha P, K., Woodruff K., St Clair P., Bsoul S., Werner S. L. and Ghosh Choudhury G. Concerted action of Smad and CREB-binding protein regulates bone morphogenetic protein-2-stimulated osteoblastic colony-stimulating  factor-1  expression.  J Biol Chem, 281: 20160-20170, 2006.
    54. Ghosh Choudhury G., Mahimainathan L., Venkatesan B., Das F. and Ghosh-Choudhury N. c-Src couples PI 3 kinase/Akt and MAPK signaling to PDGF-induced DNA synthesis in mesangial cell. Cellular Signalling. 18: 1854-1864, 2006.
    55. Block K., Ricono J. M., Lee D-Y, Bhandari B., Ghosh Choudhury G., Abboud H. E. and Gorin Y. Arachidonic acid-dependent activation  of p22phox-based NADP(H) oxidase mediates angiotensin II-mediated mesangial cell protein synthesis and  fibronectin expression via Akt/PKB. Antioxidant & Redox Signaling, 8: 1497-1508, 2006.
    56. Venkatesan B. A., Mahimainathan L, Ghosh-Choudhury N., Gorin Y., Bhandari B., Valente J., Abboud H. E., and Ghosh Choudhury G. PI 3 kinase-dependent Akt kinase and PKCε independently regulate interferon-γ-induced STAT1α serine phosphorylation to induce monocyte chemotactic protein-1 expression. Cellular Signlling, 18: 508-518, 2006.
    57. Kim N. H., Rincon-Choles H., Bhandari B., Ghosh Choudhury G., Abboud H. E. and Gorin Y. Redox dependence of glomerular epithelial cell hypertrophy in response to glucose. Am J. Physiol Renal Physiol, 290: F741-F751, 2006.
    58. Feliers D., Gorin Y., Ghosh Choudhury G., Abboud H. E. and Kasinath B. S. Angiotensin II stimulation of VEGF mRNA translation requires production of reactive oxygen species. Am J Physiol Renal Physiol. 290: F927-F936, 2006.
    59. Mahimainathan L., Ghosh-Choudhury N., Venkatesan B. A., Danda R. S. and Ghosh Choudhury G. EGF stimulates mesangial cell mitogenesis via PI3-kinase-mediated MAPK- dependent and AKT kinase-independent manner: Involvement of c-fos and p27Kip1. Am J Physiolo Renal Physiol 289: F72-F82, 2005.
    60. Mariappan M. M., Senthil D., Natarajan K. S., Ghosh Choudhury G. and Kasinath B. S. PLCgamma-Erk axis in VEGF-induced eIF4E phosphorylation and  protein  synthesis  in renal epithelial cells. J Biol Chem. 280: 28402-28411, 2005.
    61. Feliers D, Chen X, Akis N., Ghosh Choudhury G., Madaio M., Kasinath B. VEGF regulation of endothelial nitric oxide synthase in glomerular endothelial cells. Kidney Int. 68:1648- 1659, 2005.
    62. Feliers D., Duraisamy S., Barnes J. L., Ghosh Choudhury G. and Kasinath B. S. Translational regulation of vascular endothelial growth factor expression in renal epithelial cells by angiotensin II. Am J Physiol Renal Physiol. 288: F521-F529, 2005.
    63. Ghosh Choudhury G. A linear signal transduction pathway involving PI 3 kinase, PKCε and MAPK in mesangial cell regulates interferon-γ-induced STAT1α transcriptional activation. J Biol Chem 279, 27399 – 27409, 2004.
    64. Mahimainathan L. and Ghosh Choudhury G. Inactivation of platelet-derived growth factor receptor by the tumor suppressor PTEN provides a novel mechanism of activation of the phosphatase. J Biol Chem 279: 15258 – 15268, 2004.
    65. Ghosh  Choudhury  G.  and  Abboud  H.  E.     Tyrosine phosphorylation-dependent PI 3 kinase/Akt signal transduction regulates TGFβ-induced fibronectin expression in mesangial cells. Cell. Signal, 16: 31-41,2004.
    66. Gorin Y., Ricono  J. M., Wagner B., Kim N. H., Bhandari B., Ghosh Choudhury G. and Abboud H. E. Angiotensin II-induced Erk1/Erk2 activation and protein synthesis are redox- dependent in glomerular mesangial cells. Biochem J 381: 231 – 239, 2004
    67. Pontrelli P., Ranieri E., Ursi M., Ghosh Choudhury G., Gesualdo L., Paolo Schena F. and Grandaliano G. Jun-N-terminal kinase regulates thrombin-induced PAI-1gene expression in proximal tubular epithelial cells. Kidney Int 65: 2249 – 2261, 2004.
    68. Ye P., Habib S. L., Ricono J., Kim N.-H., Ghosh Choudhury G., Barnes J. L., Abboud H. E. and Arar M. Fibronectin induces ureteric bud cells branching and cellular cord and tubule formation. Kidney Int 66: 1356-1364, 2004..
    69. Senthil D., Ghosh Choudhury G. and Kasinath B. S. Vascular endothelial  growth  factor induces protein synthesis in renal epithelial cells: a potential role in diabetic nephropathy. Kidney Int 64: 468-479, 2003.
    70. Ghosh-Choudhury N., Abboud S. L., Mahimainathan L., Chandrasekar B. and Ghosh Choudhury G. Phosphatidylinositol 3-kinase regulates bone morphogenetic protein-2 (BMP- 2)-induced myocyte enhancer factor 2A-dependent transcription of BMP-2 gene in cardiomyocyte precursor cells. J Biol Chem 278: 21998-22005, 2003.
    71. Gorin Y., Ricono, J. M., Kim N-H., Bhandari B., Ghosh Choudhury G. and Abboud H. E. Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells. Am J. Physiol Renal Physiol. Am J Physiol Renal 285: F219-229, 2003.
    72. Ghosh Choudhury G., Lenin M., Calhaun C., Zhang J.-H. and Abboud H. E. PDGF inactivates forkhead family transcription factor by activation of Akt in glomerular mesangial cells. Cell. Signalling. 15: 161-170, 2003.
    73. Ghosh-Choudhury N., Abboud S. L., Chandrasekar B. and Ghosh Choudhury G. BMP-2 regulates cardiomyocyte contractility in a phosphatidylinositol 3 kinase-dependent manner. FEBS Letters, 544: 181-184, 2003.
    74. Ghosh-Choudhury N, Abboud SL, Nishimura R, Celeste A, Mahimainathan L, and Ghosh Choudhury  G.                            Requirement of BMP-2-induced phosphatidylinositol 3 kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene transcription.  J. Biol. Chem. 277: 33361-33368, 2002.
    75. Senthil D., Ghosh Choudhury G., Bhandari B. and Kasinath B. S. The type 2 vascular endothelial growth factor receptor recruits insulin receptor substrate-1 in its signaling pathway. Biochem J 368: 49-56, 2002.
    76. Senthil D., Ghosh Choudhury G., Abboud H. E., Sonenberg N. and Kasinath B. S. Regulation of protein synthesis by IGF-1 in proximal tubular epithelial cells. Am. J. Physiol Renal Physiol. 283: F1226-F1236, 2002.
    77. Ricono J. M., Arar M., Ghosh Choudhury G. and Abboud H.E. Effect of platelet-derived growth factor (PDGF) isoforms in rat metanephric mesenchymal cells. Am. J. Physiol Renal Physiol. 282: F211-F219, 2002.
    78. Gorin Y., Kim N.-H., Feliers D., Bhandari B., Ghosh Choudhury G. and Abboud H. E. Angiotensin II activates Akt/Protein kinase B by an arachidonic acid/redox-dependent pathway and independent of phosphatidylinositol 3-kinase. FASEB J. 15: 1909-1920, 2001.
    79. Ghosh-Choudhury N., Ghosh Choudhury G., Harris M. A., Wozney J., Mundy G. R., Abboud S. L. and Harris S. E. Autoregulation of mouse BMP-2 gene transcription is directed by the proximal promoter element. Biochem Biophys Res. Commun. 286: 101-108, 2001.
    80. Ghosh Choudhury G., Zhang J.-H., Ghosh-Choudhury N. and Abboud H.E. Ceramide blocks PDGF- induced DNA synthesis in mesangial cells via inhibition of Akt kinase in the absence of apoptosis. Biochem Biophys Res Commun 286: 1183-1190, 2001.
    81. Ghosh Choudhury G. Akt serine threonine kinase regulates PDGF-induced DNA synthesis in glomerular mesangial cells: Regulation of c-fos and p27Kip1  gene  expression.  J.  Biol. Chem. 276: 35636-35643, 2001.
    82. Feliers D., Senthil D., Faulkner J.L., Duch J., Lee A.V., Abboud H.E., Ghosh Choudhury G. and Kasinath B.S. Activation of renal signaling pathways in db/db mice with type  2 diabetes. Kidney Int 60: 495-504, 2001.
    83. Duraisamy S., Faulkner J. L., Ghosh Choudhury G., Abboud H. E. and Kasinath B. S. Angiotensin II inhibits insulin-stimulated phosphorylation of eukaryotic initiation factor 4E binding protein-1 in proximal tubular epithelial cells. Biochem J. 360: 87-95, 2001.
    84. Bhandari B.K., Feliers  D., Duraisamy  S., Stewart J.L., Gingras  A., Abboud H.E., Ghosh Choudhury G., Sonenberg N. and Kasinath B.S. Insulin regulation of protein translation repressor 4E BP-1, an eIF4E-binding protein, in renal epithelial cells. Kidney Int 59: 866- 875, 2001.
    85. Ghosh Choudhury G. and Ricono J. M. Increased effect of interferonγ on PDGF-induced c- fos gene transcription in glomerular mesangial cells: Differential effect of the transcriptional coactivator CBP on STAT1α. Biochem Biophys. Res. Commun. 273: 1069-1077, 2000.
    86. Ghosh-Choudhury N., Ghosh Choudhury, G. Celeste A., Ghosh P. M., Moyer M, Abboud S.L. and Kreisberg J. Bone Morphogenetic Protein-2 induces cyclin kinase inhibitor p21 and hypophosphorylation of retinoblastoma protein in estradiol treated MCF-7 human  breast cancer cells. Biochim Biophys Acta 1497: 186-196, 2000.
    87. Ghosh-Choudhury N., Woodruff K., Qi W., Celeste A., Abboud S. L. and Ghosh Choudhury G. Bone morphogenetic protein-2 blocks MDA MB 231 human breast cancer cell proliferation by inhibiting cyclin-dependent kinase-mediated retinoblastoma protein phosphorylation. Biochem Biophys. Res. Commun. 272: 705-711, 2000.
    88. Arar M., Su Y., Elshihabi I., Barnes J. L., Ghosh Choudhury G. and Abboud H.E. Platelet- derived growth factor receptor beta regulates migration and DNA synthesis in metanephric mesenchymal cells. J. Biol. Chem. 275: 9527-9533, 2000.
    89. Ghosh Choudhury G., Grandaliano G., Karamitsos C., Katz M. and Abboud H. E. Activation of PLC and PI 3 kinase by PDGF receptor a is not sufficient for  DNA  synthesis  and migration in mesangial cells. Kidney Int. 57: 908-917, 2000.
    90. Bardgette J., Abboud H. E. and Ghosh Choudhury  G.  Activation  of  STAT1α  by phosphatase inhibitor vanadate in glomerular mesangial cells: Involvement of tyrosine and serine phosphorylation. J. Receptor and Signal Transduction. 19: 865-884, 1999.
    91. Ghosh Choudhury G., Jin D.-C., Kim T.-S., Celeste A., Ghosh-Choudhury N. and Abboud H. E. Bone morphogenetic protein-2 inhibits  MAPK-dependent  Elk-1  transactivation  and DNA synthesis induced by EGF in mesangial cells. Biochem. Biophys. Res. Commun. 258: 490-496. 1999.
    92. Ghosh Choudhury G., Kim Y.S., Simon M., Ghosh Choudhury N., Wozney J., Harris S. and Abboud H.E. Bone morphogenetic protein 2 inhibits PDGF-induced c-fos gene transcription and DNA synthesis in mesangial cells: Involvement of mitogen activated protein kinase. J. Biol. Chem., 274: 10897-10902. 1999.
    93. Ghosh Choudhury G. Ghosh-Choudhury N. and Abboud H. E. Association and direct activation of STAT1α by platelet-derived growth factor receptor. J. Clin. Invest. 101: 2751- 2760, 1998.
    94. Grandaliano G., Ghosh Choudhury G., Poptic E., Woodruff K, A., Barnes J.L. and Abboud H.E. Thrombin regulates PDGF expression in bovine glomerular endothelial cells. J. Am. Soc. Nephrol. 9: 583-589 1998.
    95. Abboud, S.L., Woodruff, K.A. Ghosh Choudhury, G. Retroviral-mediated gene transfer of CSF-1 into op/op stromal cells to correct defective osteoclastogenesis. J. Cell Physiol. 176: 323-331, 1998.
    96. Ghosh Choudhury G., Karamitsos, C., Hernandez, J., Gentilini, A., Berdgette, J. and Abboud, H.E. PI 3 kinase and MAPK regulate mesangial cell proliferation and migration in response to PDGF. Am. J. Physiool. 273: F931-F938, 1997.
    97. Marra, F., Gentilini, A., Pinzani, M., Ghosh Choudhury, G., Parola,M., Herbst, H., Dianzani, M.U., Laffi, G., Abboud, H.E. and Gentilini, P. Phosphatidylinositol 3 kinase is required for platelet-derived growth factor’s action on hepatic stellate cells. Gastroenterology, 112: 1297-1306. 1997.
    98. Marra F., Ghosh Choudhury G. and Abboud H.E. Interferon gamma-mediated activation of STAT1α regulates growth factor induced mitogenesis. J. Clin. Invest. 98: 1218-1230. 1996.
    99. Ghosh Choudhury, G., Marra, F., Kiyomoto, H. and Abboud, H.E. PDGF  stimulates tyrosine phosphorylation of JAK 1 protein tyrosine kinase in human mesangial cells. Kidney Intl.  49,:19-25. 1996.
    100. Ghosh Choudhury, G., Marra, F. and Abboud, H.E. Thrombin stimulates association of the src homology domain containing adaptor protein Nck with pp125 FAK (focal  adhesion kinase). Am. J. Physiol. 270: (Renal Fluid and Electrolyte), F295-F300.  1996.
    101. Kasinath B.S., Grellier P., Ghosh Choudhury G. and Abboud S.L. Regulation of basement membrane heparan sulfate proteoglycan, perlecan,  gene  expression  in  glomerular epithelial cells by high glucose medium. J. Cell. Physiol. 161: 131-136. 1996.
    102. Biswas P, Abboud HE, Kiyomoto H, Wenzel U, Grandaliano G, and Ghosh Choudhury G: PKCα regulates PDGF B chain gene expression in human mesangial cells. FEBS Letter 373: 146-150, 1995.
    103. Wenzel U, Fouqueray B, Biswas P, Grandaliano G, Ghosh Choudhury G, and Abboud HE: Activation of mesangial cells by phosphatase inhibitor vanadate: Potential implications for diabetic nephropathy.  J Clin Invest.  95: 1244-1252, 1995.
    104. Kiyomoto H, Fouqueray B, Abboud HE and Ghosh Choudhury G: Phorbol 12-myristate 13-acetic acid inhibits PTP1B activity in human mesangial cells: A possible mechanism of enhanced tyrosine phosphorylation.  FEBS Letters 353: 217-220, 1994.
    105. Grandaliano G, Ghosh Choudhury G, Biswas P, and Abboud HE: Mitogenic signaling of thrombin in mesangial cells: role of tyrosine phosphorylation. Am J Physiol (Renal Fluid and Electrolyte) 267: F528-F536, 1994.
    106. Marra, F, Ghosh Choudhury G, Pinzani M and Abboud HE: Regulation of platelet-derived growth factor  secretion and gene expression in human liver   fat-storing  cells. Gastroenterology 107: 1110-1117, 1994.
    107. Ghosh Choudhury G, Biswas P, Grandaliano G, Fouqueray B, Harvey SA, and Abboud HE: PDGF-mediated activation of phosphatidylinositol 3 kinase in human mesangial cell. Kidney Int 46: 37-47, 1994.
    108. Grandaliano G, Biswas P, Ghosh Choudhury G, and Abboud HE:      Simvastatin inhibits PDGF-induced DNA synthesis in human mesangial cells.  Kidney Int. 44: 503-508, 1993.
    109. Ghosh Choudhury G, Biswas P, Grandaliano G, and Abboud HE: Involvement of protein kinase Cα in platelet-derived growth factor mediated mitogenic signaling in human glomerular mesangial cells.  Am J Physiol 265: F634-F642, 1993.
    110. Heidaran MA, Molloy CJ, Pangelinan M, Ghosh Choudhury, G. Wang L-M, Fleming TP, Sakaguchi AY, and Pierce JH.  Activation of the colony-stimulating factor-1 receptor leads to the rapid tyrosine phosphorylation of GTPase-activating protein and activation of cellular p21ras.  Oncogene 7: 147-152, 1992.
    111. Sakaguchi AY, Sylvia V, Martinez L, Lalley PA, Shows TB, Han ES, Smith A.E, and Ghosh Choudhury G. Assignment of tyrosine specific T-cell phosphatase to conserved syntenic groups on human chromosome 18 and mouse chromosome 18.   Genomics 12: 151-154,1992.
    112. Ghosh  Choudhury  G,  Sylvia  V,  and  Sakaguchi  AY.     Decline of signal transduction by phospholipase Cg1 in IMR 90 human diploid fibroblasts at high population doubling levels. FEBS Letters 293: 211-214, 1991.
    113. Smith EA, Seldin MF, Martinez L, Watson ML, Ghosh Choudhury G, Lalley PA, Pierce JH, Aaronson SA, Barker J, Naylor SL, and Sakaguchi AY. The mouse W19H chromosome 5 deletion encompasses the platelet-derived growth factor receptor alpha gene. Proc Natl Acad Sci USA 88: 4811-4815, 1991.
    114. Ghosh Choudhury G, Sylvia V, Wang LM, Pierce J, and Sakaguchi AY. The kinase insert domain of colony stimulating factor-1 receptor is dispensable for CSF-1 induced phosphatidylcholine hydrolysis.  FEBS Letters, 282: 351-354, 1991.
    115. Ghosh  Choudhury  G,  Wang  LM,  and  Harvey  S,  Pierce  J,  and  Sakaguchi  AY.      Human colony stimulating factor-1 receptor associates with phosphatidylinositol 3 kinase: A mutational analysis.  J Biol Chem 266: 8068-8072, 1991.
    116. Ghosh Choudhury G, Sylvia V, Pfeifer A, Wang LM, Smith EA, and Sakaguchi AY. Human colony stimulation factor-1 receptor activates the c-Raf-1 protooncogene kinase. Biochem Biophys Res Commun 172: 154-159, 1990.
    117. Pierce JH, Cox YW, Marcos ED, Lombardi D, DiFiori PP, Anklensaria P, Veresio L, Wang LM, Ghosh Choudhury G, Sakaguchi AY, and Aaronson SA. CSF-1 induces proliferation, reversible monocytic differentiation and chemotaxis of myeloid progenitor cells transfected with human c-fms/CSF-1 receptor.  Proc Natl Acad Sci USA 87: 5613-5617, 1990.
    118. Smith A, Lalley, PA, Killary AM, Ghosh Choudhury G, Wang LM, Han ES, Martinez L, Naylor SL, and Sakaguchi AY. Sigje, a member of small  inducible  gene  family  that includes platelet factor 4 and melanoma growth stimulatory activity,  is  on  mouse chromosome 11.  Cytogenet Cell Genet 52: 194-196, 1989.
    119. Wang LM, Geihl DK, Ghosh Choudhury G, Minter A, Martinez L, Weber DK, and Sakaguchi AY. Site directed deletion mutagenesis using phagemid vectors and genetic selection.  BioTechniques 7: 1000-1010, 1989.
    120. Sakaguchi AY, Lalley PA, Ghosh Choudhury G, Martinez L, Han ES, Killary AM, Naylor SL, and Wang LM. Mouse melanoma growth stimulatory activity gene (Mgsa) is polymorphic and syntenic with W, patch, rumpwhite, and recessive spotting loci on chromosome 5. Genomics 5: 629-632: 1989.
    121. Maity SN, Banerjee A, Mukhopadhyay K., Roychoudhury S., Ghosh Choudhury G., Biswas BB, and Bhattacharyya B. Role of B-ring of colchicine in its binding to tubulin. Ind. J. Biochem. Biophys 25: 585-589, 1988.
    122. Johnson  DC,  Ghosh  Choudhury  G,  Smiley  JR,  Fallis  L,  and  Graham  FL.      Abundant expression of Herpes Simplex virus glycoprotein gB using an adenovirus vector. Virology 164:1-14: 1988.
    123. Ghosh Choudhury G, and Graham FL. Stable transfer of a mouse dihydrofolate reductase gene into a deficient cell line using human adenovirus vector. Biochem  Biophys  Res Commun 147: 964-973. 1987.
    124. Ghosh  Choudhury  G,  Haj-Ahmad  Y  and  Graham  FL.     Packaging constraint of human adenovirus type 5:  a unique role of polypetide IX. EMBO J 6: 1733-1739, 1987.
    125. Ghosh  Choudhury  G,  Bhattacharyya  B,  and  Biswas  BB.      Kinetic and thermodynamic analysis of taxol-induced purified tubulin polymerization. Biochem and Cell Biol 65: 558- 564, 1987.
    126. Ghosh  Choudhury  G,  Haj-Ahmad  Y,  Brinkley  P,  Rudy  J  and  Graham  FL.      Human adenovirus cloning vectors based on infectious  bacterial  plasmids.  Gene  50:  161-171, 1986.
    127. Bhattacharyya  B, Ghosh  Choudhury  G,  Maity  S  and  Biswas  BB.      The role of B-ring of cochicine on taxol-induce tubulin polymerization.  Annals NY Acad Sci 466: 791-793, 1986.
    128. Ghosh Choudhury G, Maity S, Bhattacharyya B and Biswas BB. B-ring of colchicine and its role in taxol-induced tubulin polymerization.  FEBS Letters 197: 31-34, 1986.
    129. Biswas  BB,  Sen  K,  Ghosh  Choudhury  G.,  and  Bhattacharyya  B.       Molecular biology of tubulin:  its interaction with drugs and genomic organization.  J Biosci 6: 431-457: 1984.
    130. Ghosh  Choudhury  G,  Benerjee  A,  Bhattacharyya  B  and  Biswas  BB.      Interaction of colchicine analogs with purified tubulin. FEBS Letters 161: 55-59, 1983.

    Papers Submitted and In Revision

    1. Sataranatarajan K. Bokov A. F., Feliers D., Lee H. J.,  Mariappan  M.  M.,  Ghosh  Choudhury  G., Barnes J. L., Richardson A. G. and Kasinath B. S Rapamycin fails to ameliorate established kidney injury and increases mortality in mice with type 2 diabetes. Submitted.
    2. Lee H. J., Feliers D., Mariappan M. M., Sataranatarajan K., Ghosh Choudhury G., Gorin Y. and Kasinath B. S. Tadalafil integrates nitric oxide-hydrogen sulfide signaling to inhibit high glucose-induced matrix protein synthesis in podocytes. Submitted.
    3. Mariappan M. M., Prasad P., D’Silva K., Cedillo E., Sataranatarajan K., Barnes J. L., Ghosh Choudhury G. and Kasinath B. S. Activation of glycogen synthase kinase  3β  ameliorates  diabetes- induced kidney injury. In Revesion.
    Review Articles and Book Chapters
    1. Kasinath B. S., Mariappan M.  M., Sataranatarajan K., Lee N. J., Ghosh Choudhury G. and Feliers D. Regulation of mRNA translation in renal physiology and disease. Am J. Physiol Renal Physiol Epub ahead of print. PMID: 19535566, 2009.
    2. Kasinath B. S., Mariappan M. M., Sataranatarajan K., Lee M. J., Ghosh Choudhury G. and Feliers D. Novel mechanism of protein synthesis in diabetic nephropathy-role of mRNA translation. Rev Endocrin Metab Disord 9: 255-266, 2008.
    3. Ghosh-Choudhury N. and Ghosh Choudhury G. Signaling crosstalk by bone morphogenetic proteins. Bone Morphogenetic proteins: From Local to Systemic Therapeutics. Ed: Slobodan Vukicevic and Kuber T. Sampath. Birkhauser Inc. pp 161- 178, 2008.
    4. Grandaliano G., Ghosh Choudhury G, Abboud H.  E.:  Transgenic animal models as a tool in the diagnosis of kidney diseases.  Sem. in Nephrol. 15, 43-49, 1995.
    5. Marra F., Ghosh Choudhury G., Bhandari B. and Abboud H. E. Biology and regulation of platelet-derived growth factor in fat storing cells and liver fibrosis. Fat Storing Cells and Liver Fibrosis. Edited by Surrenti C, Casini A, Milani S and Pinzanin M. pp209-221, Kluwer Academic Publishers, 1993.
    6. Graham F. L., Prevec I. A., Schneider M., Ghosh Choudhury G., McDermott M. and Johnson D. C. Cloning and expression of glycoprotein genes in human adenovirus vectors. Technological Advances in Vaccine Development, Liss Alan R., Inc. pp243-254, 1988.

    Abstracts  Published

    1. Bera A. Das F., Mariappan M. M., Ghosh-Choudhury N., Kasinath B. S. and Ghosh Choudhury G.. microRNA-214 (miR-214) regulates mesangial cell (MC) hypertrophy and matrix expansion through PTEN. J Am Soc Nephrol Abs  TH  PO377, p188A, 2013.
    2. Das F., Bera A., Ghosh-Choudhury N., Kasinath B. S., Abboud H. E. and Ghosh Choudhury G. PDGF launches mesangial cell proliferiation via a positive feed-back loop involving Ekk5 and Akt downstream of PI kinase. J Am Soc Nephrol Abs SA PO768, p804A, 2013.
    3. Sataranatarajan K. Bokov A. F., Feliers D., Lee H. J., Mariappan M. M., Ghosh Choudhury G., Barnes J. L., Richardson A. G. and Kasinath B. S. Rapamycin fails to ameliorate established renal injury and augments mortality in diabetic mice. J Am Soc Nephrol Abs TH PO391, p191A, 2013.
    4. Lee H. J., Feliers D., Mariappan M. M., Sataranatarajan S., Gorin Y. C., Ghosh Choudhury G. and Kasinath B. S., Tadalafil integrates nitric oxide-hydrogen sulfide- AMPK pathways to inhibit high glucose-induced matrix  protein  synthesis  in podocytes. J Am Soc Nephrol Abs SA PO326, p701A, 2013.
    5. Das F.,  Ghosh-Choudhury N., Dey N., Abboud H.  E.,  Kasinath B. S. and Ghosh Choudhury G. A signal relay from TGFb-stimulated Smad 3 to mTOR involves deptor suppression to force mesangial cell hypertrophy. J Am Soc Nephrol Abs FR OR040, p40A, 2012.
    6. Bera A, Dey N., Das F., Kasinath B. S., Abboud H. E., Ghosh-Choudhury N. and Ghosh Choudhury G. microRNA-21-dependent positive feedback loop involving NFkB regulates renal cancer cell proliferation. J Am Soc Nephrol Abs TH-PO177, p134A, 2011.
    7. Das F.,  Dey N., Ghosh-Choudhury N., Kasinath B.  S.,  Abboud H. E. and Ghosh Choudhury G. Hyperactive TORC1 and TORC2 launch Hif1a-dependent expression of PTEN to regulate phosphorylation of Akt in tuberous sclerosis complex (TSC). J Am Soc Nephrol Abs SA-PO2361, p662A, 2011.
    8. Dey N.,  Das F., Ghosh-Choudhury N., Kasinath B. S., Abboud H. E. and Ghosh Choudhury G. Reciprocal expression of microRNA-241 (miR-214) and insulin-like growth factor-1 receptor (IGF-1R) dictates renal cell carcinoma cell proliferation via Akt/TORC1 circuit. J Am Soc Nephrol Abs SA PO2431, p677A, 2011.
    9. Eid A. A., Ford B. M., Barnes J. L., Gorin Y. C., Ghosh Choudhury G. and Abboud H.E. mTOR regulates Nox4-mediated podocyte loss in diabetic renal injury. J Am Soc Nephrol Abs TH-PO542,p236A, 2011.
    10. Dey N., Ghosh-Choudhury N., Das F., Mariappan M. M., Mandal C., Kasinath B. S. and Ghosh Choudhury G. Micro-RNa-21 (miR-21)  targets  PTEN  to  regulate mesangial cell hypertrophy and fibronectin expression by high glucose. J Am Soc Nephrol Abs TH-FC141, 31A, 2010.
    11. Mandal C. C., Ghosh-Choudhury N., Yoneda T., Ghosh Choudhury G. and Ghosh- Choudhury N. Simvastatin prevents breast cancer skeletal metastasis by increasing p53 levels to increase PTEN and inhibit CD44 expression. Cancer Res 70, N0 20, 2010.
    12. Mariappan M. M., D’Silva K., Lee M.-J., Sataranatarajan K., Ghosh Choudhury G. and Kasinath B. S. High glucose-stimulated UBF-1 activation increases ribosome biogenesis for enhanced protein synthesis in glomerular epithelial cells. J Am Soc Nephrol Abs TH-PO403, 202A, 2010.
    13. Lee H.-J., Feliers D., Mariappan M. M., Sataranatarajan K., Ghosh Choudhury G. and Kasinath B. S. Hydrogen sulfide activates AMPK and inhibits high glucose induction of protein and matrix laminin synthesis in glomerular endothelial cells. J Am Soc Nephrol Abs SA-PO2528, 691A, 2010.
    14. Mariappan M. M., Sataranatarajan K., Ghosh Choudhury G. and Kasinath B. S. Amelioration of diabetes-induced renal injury by sodium nitroprusside is associated with glycogen synthase kinase 3 beta activation. J Am Soc Nephrol Abs TH-PO416, 205A, 2010.
    15. Mandal C., Ghosh-Choudhury N., Yoneda T., Ghosh Choudhury G. and Ghosh- Choudhury N. Unveiling dual function of p53 in preventing breast cancer bone metastasis by simvastatin targeting CD44 and PTEN J Bone and Mineral Res 25, p, S69, 2010.
    16. Das F., Ghosh-Choudhury N., Mandal C., Dey N., Kasinath B. S. and Ghosh Choudhury G. A feedback loop in high glucose-induced inactivation of FoxO1 regulates Akt activation, mesangial cell hypertrophy and fibronectin expression via downregulation of catalase. J Am Soc Nephrol Abs F-PO1113, 366A, 2010.
    17. Das F., Ghosh-Choudhury N., Dey N., Kasinath B. S. and Ghosh Choudhury G. S6 kinase/p90Rsk axis regulates eEF2 dephosphorylation to induce TGF-beta- stimulated mesangial cell (MC) hypertrophy. J Am Soc  Nephrol  Abs  F-PO1775, 520A, 2009.
    18. Mandal C., Ghosh-Choudhury G., Yoneda T., Ghosh-Choudhury N. Omega-3 fatty acids (OFAs) intercept miR-21 and miR-214 targeting PTEN to prevent breast cancer bone metastasis. ASBMR 31st Annual Meeting, Denver, Colorado, p, SU0113, September 2009.
    19. New D. D., Block K., Gorin Y., Ghosh Choudhury G. and Abboud H. E.  IGF-1 increases expression of fibronectin by activation of Nox4-dependent PI 3 kinase/Akt signaling. J Am Soc Nephrol Abs TH-PO714, 277A, 2009.
    20. Dey N., Ghosh-Choudhury N., Das F., Kasinath B. S. and Ghosh Choudhury G. Phosphorylated PRAS40 is an intermediate in high glucose-induced hypertrophy of mesangial cells (MC) and diabetic glomeruli. J Am  Soc  Nephrol  Abs  TH-PO772, 289A, 2009.
    21. Mandal C., Ganapathy S., Ghosh-Choudhury G., and Ghosh-Choudhury N. BMP-2- stimulated Nox4-PI 3 kinase-Akt signaling axis  induces  osteoblast  (OB) differentiation. ASBMR 31st Annual Meeting, Denver, Colorado, p,  MO0184, September 2009.
    22. Sataranatarajan K., Feliers D., Mariappan M. M., Lee M.-J., Jemenenez F., Chen Y., Ghosh Choudhury G., Ahuja S. and Kasinath B. S. Toll-like receptor 4 knockout (TLR4ko) mice are  resistant to  diabetic  kidney injury. J  Am Soc  Nephrol Abs  SA FC476, p107A, 2008.
    23. Wagner B., Ricono J., Gorin Y., Arar M., Kazlauskas A., Ghosh Choudhury G. and Abboud H. E. PDGF receptor beta modulates metanephric mesenchyme chemotaxis induced by PDGF AA. J Am Soc Nephrol Abs TH-PO041, p120A, 2008.
    24. Das F., Ghosh-Choudhury N., Venkatesan B., Kasinath B. S. and Ghosh Choudhury G.  Mnk-1-mediated   phosphorylation   of  eIF4E   is  required   for  TGFbeta-induced mesangial cell (MC) hypertrophy. J Am Soc Nephrol Abs TH-PO116, 137A, 2008.
    25. Mandal C. C., Ghosh Choudhury G., Ganapathy S., Harris S. E. and Ghosh- Choudhury N. BMP-2-stimulated signaling niche in osteoblasts comprising of Smad and PI 3 kinase/Akt regulates NFATc1 expression and its nuclear translocation. ASBMR 30th  Annual Meeting, Montreal, Canada, 2008.
    26. Venkatesan B., Das F., Ghosh-Choudhury N., Kasinath B. S., Abboud  H.  E.  and Ghosh Choudhury G. Resveratrol targets PTP1B to inhibit PDGF-induced mesangial cell (MC) proliferation. J Am Soc Nephrol Abs TH-PO179, p149A, 2008.
    27. Ghosh Choudhury G., Venkatesan B., Das F., Habib S. L., Ghosh-Choudhury N., Kasinath B. S. and Abboud H. E. Mechanism for reduced malignancy of TSC2 null tumors. J Am Soc Nephrol Abs TH-PO217, 157A, 2008.
    28. Dey N., Ghosh-Choudhury N., Li X., Das F., Venkatesan B.,  Kasinath  B.  S.  and Ghosh Choudhury G. Proline-rich Akt substrate 40 (PRAS40) regulates high glucose-induced protein synthesis in mesangial cells (MC). J Am Soc Nephrol Abs SA-PO2382, p646A, 2008.
    29. Mariappan M. M., Sataranatarajan K., Lee M.-J., Ghosh Choudhury G. and Kasinath B. S. High glucose-induced protein synthesis in rat glomerular  endothelial  cells (GEC) involves ribosomal biogenesis. J Am Soc Nephrol Abs SA-PO2386, p647A, 2008.
    30. Mandal C. C., Ghosh Choudhury G. and Ghosh-Choudhury N.BMP-2 stimulates a feedback activation loop for expression of NFATc1 in osteoblasts. ASBMR  30th Annual Meeting, Montreal, Canada, 2008.
    31. Mahimainathan L., Ghosh-Choudhury N., Abboud H. E. and Ghosh Choudhury G. Tumor suppressor PTEN is the latest taget of hypoxia inducible factor1-alpha (Hif1a). J am Soc Nephrol Abs F-FC 132, p28A, 2007.
    32. Mandal C. C., Drissi H., Ghosh Choudhury G. and Ghosh-Choudhury N. BMP-2 inducible osterix increases CSF-1 and RANKL/OPG ratio to induce osteoclast maturation. ASBMR 29th Annual Meeting, Honolulu, Hawaii, 2007.
    33. Das F., Ghosh-Choudhury N., Venkatesan B., Mahimainathan L.  and  Ghosh Choudhury G. Role of linker region phosphorylation of Smad 3 in PAI-1 expression in mesangial cells (MC). J am Soc Nephrol Abs F-PO471, p204A, 2007.
    34. Mandal C. C., Ghosh Choudhury G. and Ghosh-Choudhury N. Osteoblastic master regulator osterix mediates feedback regulation of BMP-2 auto-expression via PI 3 kinase/Akt signaling. ASBMR 29th Annual Meeting, Honolulu, Hawaii, 2007.
    35. Das F.,  Ghosh-Choudhury N., Li  X.,  Mahimainathan L.  and Ghosh  Choudhury G. Transcriptional coactivator CBP regulates  TGFbeta  (TGFb)-induced  PAI-1 expression by acetylation of Smad 3 in mesangial cells (MC). J am Soc Nephrol Abs F-PO472, p204, 2007.
    36. Das F., Venkatesan B., Ghosh-Choudhury N., Mahimainathan L., Abboud H. E. and Ghosh Choudhury G. Mechanism of TGFbeta inhibition of PDGF-induced DNA synthesis in mesangial cells (MC). J am Soc Nephrol Abs SA-PO163, p380A, 2007.
    37. Das F., Venkatesan B., Kasinath B. S. and Ghosh Choudhury G. Raptor-Rictor antagonism regulates TGFbeta (TGFb)-induced protein synthesis in mesangial cells (MC). J am Soc Nephrol Abs SA-PO164, 380A, 2007.
    38. Venkatesan B., Ghosh-Choudhury N., Mahimainathan L., Kasinath B. S. and Ghosh Choudhury G. SIRT1 (Silence Information Regulator1) regulates p53-dependent PTEN expression in high glucose-stimulated mesangial cells (MC). J am Soc Nephrol Abs SU-PO322, p653A, 2007.
    39. Mariappan M. M., Satanatarajan K., Ghosh Choudhury G. and Kasinath B. S. Role of GSK3beta (GSK3b) inactivation in high glucose(HG)- and high insulin (HI)-induced extracellular matrix protein synthesis in proximal tubular epithelial (MCT) cells. J am Soc Nephrol Abs SU-PO310, p651A, 2007.
    40. Lee M-J., Satanatarajan K., Mariappan M. M., Feliers D., Ghosh Choudhury G. and Kasinath B. S. Resveratrol ameliorates reanl hypertrophy in diabetic mice. J am Soc Nephrol Abs F-PO307, p170A, 2007.
    41. Sataranatarajan K., Mariappan M. M., Lee M.-J, Feliers D., Ghosh Choudhury G. and Kasinath B. S. Regulation of elongation phase of mRNA translation in diabetic nephropathy-Amelioration by rapamycin. J  am Soc Nephrol Abs F-PO306, p170A, 2007.
    42. Mahimainathan L., Ghosh-Choudhury N., Habib S., Abboud H. E. and Ghosh Choudhury G. Antagonistic relationship between tuberin and PTEN is mediated by hypoxia-inducible factor1a (Hif1a). J Am Soc Nephrol Abs TH-PO145, p137A, 2006.
    43. Mahimainatha L., Das F., Ghosh-Choudhury N., Gorin Y., Kasinath B. S., Abboud H.E. and Ghosh Choudhury G. A cross talk between small GTPase Rac1 and Rheb regulates IGF 1-induced protein synthesis in mesangial cell (NC). J Am Soc Nephrol Abs SA-PO788, p741A, 2006.
    44. Venkatesan B., Mahimainatha L. and Ghosh Choudhury G. Signal relay from poshopholipase C (PLC) and Src to phosphatidylinositol (PI) 3 kinase/Akt stimulates transforming growth factor-beta (TGFb)-induced fibronectin expression in mesangial cell (MC). J Am Soc Nephrol Abs TH-PO463, p206A, 2006.
    45. Ghosh Chouhdury G., Ghosh Choudhury N., Mahimianathan L. and Das  F. Transforming growth factor-beta (TGFb)-stimulated PI 3 kinase/Akt signaling targets Smad 3 transactivation for PAI-1 gene expression in mesangial cell (MC). J Am Soc Nephrol Abs TH-PO465, p207A, 2006.
    46. Venkatesan B., Mahimainathan L. and Ghosh Choudhury G. Sprouty-2 (Spry-2) intercepts MAPK-dependent transcription and mTOR mediated mRNA translation to inhibit PDGF-induced mitogenesis in mesangial cell (MC). J Am Soc Nephrol Abs TH-PO151, p138A, 2006.
    47. Das F., Mahimainathan L., Kasinath B. S., Ghosh-Choudhury N. and Ghosh Choudhury G. Mechanism of transforming growth factor-beta (TGFb)-induced protein synthesis in mesangial cell hypertrophy. J Am Soc Nephrol Abs F-PO297, p400A, 2006.
    48. Lee M. J., Feliers D., Mariappan M. M., Sataranatarajan K., Mahimainathan L., Musi N., Weinberg J. Ghosh Choudhury G. and Kasinath B. S. A role for AMP-acitvated protein kinase (AMPK) in diabetes-induced renal hypertrophy. J Am Soc Nephrol Abs F-PO299, p400A, 2006.
    49. Sataranatarajan K., Mariappan M. M., Feliers D., Lee M. J., Ghosh Choudhury G., Barnes J. L. and Kasinath B. S. Amelioration of Type 2 diabetes-associated kidney diseases by mammalian target of rapamycin (mTOR) inhibition. J Am Soc Nephrol Abs TH-PO88, p124A, 2006.
    50. Mariappan M. M., Feliers D., Ghosh Choudhury G. and Kasinath B. S. Stimulation of laminb1 (Lamb1) mRNA translation by high glucose (HG), high insulin (HI) and their combination (HG + HI) in proximal tubular epithelial (MCT) cells. J Am Soc Nephrol Abs SA-PO104, p598A, 2006.
    51. Feliers D., Lee M. J., Ghosh Choudhury G., Bomszyk K. and Kasinath B. S. Role of Src and PKCd in the regulation of heterogeneous nuclear ribonuclear protein K (hnRNPK) in diabetic nephropathy. J Am Soc Nephrol Abs SA-PO108, p599A, 2006.
    52. Filiers D., Gorin Y., Ghosh Choudhury G., Abboud H. E., Kasinath B. S. Angiotensin II-induced rapid phase increase in VEGF mRNA translation in renal tubular epithelial cells is dpendent on reactive oxidative species. Diabetes  54,  Supplement  1,  Abs 826P, pA202, 2005.
    53. Mahimainathan L. and Ghosh Choudhury G. High glucose-induced  mesangial hypertrophy is mediaed by PTEN, a target of of TGFb. J Am Soc Nephrol. Abs TH- FC015, p3A, 2005.
    54. Venkatesan B., Mahimainathan L, Gorin Y., Abboud H. E., Ghosh Choudhury G. Activation of signaling complex containing PKC-epsilon (PKCe) and Akt kinase by Phosphatidylinositol 3 kinase (PI 3-kinase) regulates interferon-g (IFNg)-induced monocyte chemotactic protein-1 (MCP-1). J Am Soc Nephrol. Abs F-PO171, p375A, 2005.
    55. Venkatesan B., Mahimainathan L., Dai Q. and Ghosh Choudhury G. Hydrogen peroxide (H2O2)-iinduced oxidative stress-mediated inactivation of Foxo1 regulates catalase expression in mesangial cells (MC). J Am Soc Nephrol.  Abs  F-PO483, p439A, 2005.
    56. Mahimainathan L., Ghosh-Choudhury N., Gorin Y., Mummidi s., Kasinath B. S., Abboud H. E. and Ghosh Choudhury G. Rheb trafficks IGF-1 signals in renal cells: Role of reactive oxygen species (ROS). J Am Soc Nephrol. AbsSA- PO177, p598A, 2005.
    57. Ghosh Choudhury G., Dai Q., Venkatesan B., Mahimainathan L. PI 3 kinase/Akt signaling cooperates with Smad 3 to regulate TGFb-induced plasminogen activator inhibitor-I (PAI-I) expession in mesangial cells (MC). J Am Soc Nephrol. Abs SA- PO233, p609A, 2005.
    58. Feliers D., Gorin Y., Ghosh Choudhury G., Abboud H. E. and Kasinath B. S. Angiotensin II-induced rapid phase increase in VEGF mRNA translation in proximal tubular epithelial (MCT) cells is dependent on reactive oxygen species (ROS). J Am Soc Nephrol. Abs SA-PO200, p603A, 2005A.
    59. Nataranatarajan K., Mariappan M. M., Ghosh Choudhury G. and Kasinath B. S. Dual regulation of elongation phase of laminin mRNA translation  by high  glucose (HG) and high insulin (HI) in proximal tubular epithelial (MCT) cells. J Am Soc Nephrol. Abs F-PO307, p403A, 2005.
    60. Mariappan M. M., Ghosh Choudhury G. and Kasinath B. S.  Rapid  stimulation  of laminin beta1 (LAM B1) synthesis by high glucose (HG), high insulin (HI) and their combination (HG+HI) is required by mRNA translation in proximal trubular epithelial (MCT) cells. J Am Soc Nephrol. Abs F-PO300, p401A, 2005.
    61. Lee M-J., Feliers D., Mariappan M. M., Natarajan K.,Mahimainathan L.,  Musi  N., Ghosh Choudhury G., and Kasinath B. S. AMP kinase (AMPK)- a new regulator of renal hypertrophy in diabetes. J Am Soc Nephrol. Abs FTH-PO356, p196A, 2005.
    62. Feliers D., Lee J-J., Ghosh Choudhury G., Bomsztyk K. and Kasinath B. S. Role of heterogeneous nuclear ribonucleoprotein K (hnRNPK) in diabetic renal disease. J Am Soc Nephrol. Abs F-PO313, p404A, 2005.
    63. Gorin Y., Block K., Ricono J. M., Kim N-H., Bhandari B., Ghosh Choudhury G. and Abboud H. E. Arachidonic acid-dependent activation of a Nox4/p22phox-based NAD(P)H oxidase mediates angiotensin II-induced mesangial cell protein synthesis and fibronectin synthesis via activation of Akt/PKB. J Am Soc Nephrol. Abs F-FC014, p40A, 2005.
    64. Mahimainathan L, Danda R, Ghosh Choudhury G. p27Kip1 cyclin kinase inhibitor regulates epidermal growth factor (EGF)-induced DNA synthesis via phosphatidylinositol 3 kinase (PI 3 K)- and PDK-1-dependent MAPK activity in mesangial cells (MC). J Am Soc Nephrol. Abs F-FC008, p2A, 2004.
    65. Venkatesan B., Mahimainathan L. Ghosh Choudhury G. Two signals emanating from phosphatidylinositol 3 kinase (PI 3-K) regulate interferon-gamma (IFN-g)-induced monocyte chemotactic protein-1 (MCP-1) expression in mesangial cells. J Am Soc Nephrol. Abs F-PO764, p234A, 2004.
    66. Feliers D., Ghosh Choudhury G., Kasinath B. S. Protein translation as a mechanism of angiotensin II (Ang II)-induced rapid increase in VEGF synthesis. J Am Soc Nephrol. Abs F-PO150, p98A, 2004.
    67. Filiers D., Gorin Y., Ghosh Choudhury G., Abboud H. E., Kasinath B. S. Angiotensin II (Ang II)-induced rapid phase increase in VEGF mRNA translation in renal proximal tubular epithelial cells is dependent on reactive oxygen species (ROS). J Am Soc Nephrol. Abs SA-PO665, p448A, 2004.
    68. Chen X, Ghosh Choudhury G., Madaio M., Kasinath B. S. A role for VEGF in high glucose induction of VCAM-1 in glomerular endothelial (G-endo) cells. J Am Soc Nephrol. Abs SA-PO839, p484A, 2004.
    69. Mariappan M., Ghosh Choudhury G., Kasinath B. S., Translational regulation  of laminin synthesis by glucose and insulin in proximal tubular epithelial (MCT) cells. J Am Soc Nephrol. Abs SA-PO886, p493A, 2004.
    70. Mahimainathan L, Ghosh Choudhury G. Tumor suppressor PTEN regulates TGFb and high glucose-induced mesangial cell hypertrophy: Involvement of Akt kinase via PI 3 kinase. J Invest Med Abs 247, p. S301, 2004.
    71. Feliers D., Ghosh Choudhury G., Barnes J. L., Kasinath B. S. Angiotensin II (AII) regulation of vascular endothelial growth factor (VEGF) synthesis in proximal tubular epithelial cells (MCT) by protein transation. J Invest Med. Abs 250, p. S301, 2004.
    72. Chen X., Akis N., Ghosh Choudhury G., Madio M., Kasinath B. S. Dual signaling pathways regulate vascular endothelial growth factor (VEGF) induction of eNOS in glomerular endothelial (G Endo) cells. J Invest Med Abs 352, p. S320, 2004.
    73. Mariappan M., Ghosh Choudhury G. Kasinath B. S. Novel role for PLC in regulation of VEGF-induced Erk activation in proximal tubular epithelial cells and  its  role  in protein synthesis. J Invest Med. Abs. 353, p. S320, 2004.
    74. Wagner B., Gorin Y., Ghosh Choudhury G., Ricono J. M., Simon M.,  Chen  Y., Abboud H. E. NADPH oxidase signaling in platelet-derived growth factor-BB- stimulated metanephric mesenchymal cells. J Invest Med. Abs 351, p. S320, 2004.
    75. Gorin Y., Ricono J. M., Wagner B., Kim N. H., Bhandari B., Ghosh Choudhury G., Abboud H. E. NOX4 mediates angiotensin II-induced mesangial cell hypertrophy via activation of Akt/protein kinase B. J Invest Med. Abs 357, pS321, 2004.
    76. Feliers D., Senthil D., Ghosh Choudhury G., Madaio M. S., Kasinath B. S. Vascular endothelial growth factor (VEGF) regulation expression in proximal tubular epithelial cells (MCT) by angiotensin (II) J Am Soc Nephrol. Abs SA-PO483, p 402A, 2003
    77. Chen X., Feliers D., Akis A., Ghosh Choudhury G., Madaio M. S., Kasinath B. S. Vascular endothelial growth factor (VEGF) regulation of  eNOS  in  glomerular endothelial (G Endo) cells. J Am Soc Nephrol Abs SU-PO071, p553A, 2003.
    78. Mahimainathan L, Ghosh Choudhury G. TGFb and high glucose downregulates the tumor supprrssor protein PTEN (phosphatase and tensin homolog deleted on chromosome 10) to regulate mesangial cell hypertrophy. J Am Soc Nephrol. Abs SU- PO061, p551A, 2003.
    79. Ghosh Choudhury G. Phosphatidylinositol 3 kinase (PI 3-K)-sensitive PKC-epsilon (PKCe) mediates interferon-gamma (IFN-g)-induced STAT1-alpha (STAT1a) transcriptional activity in mesangial cells. J Am Soc Nephrol Abs. F-PO086, p.83A, 2003.
    80. Mariappan M., Senthil D., Ghosh Choudhury G., Kasinath B. S. Novel role of Src and PLC in regulation of VEGF-induced Erk activation in proximal tubular epithelial cells and its role in proteinsynthesis. J Am Soc Nephrol. Abs F-PO104, p.87A, 2003.
    81. Gorin Y., Ricono J. M., Kim N. H., Bhandari B., Ghosh Choudhury G., Abboud H. E. Nox4 mediates angiotensin II-meidated mesangial cell hypertrophy via actibation of Akt/protein kinase B. J Am Soc Nephrol. Abs F-PO124, p91A, 2003.
    82. Wagner B., Gorin Y., Ricono J, M., Ghosh Choudhury G., Abboud H. E. Nox4 mediates actons of platelet-derived growth factor receptorb in metanephric mesenchymal cells. J Am Soc Nephrol. Abs SA-PO271, p.357A., 2003.
    83. Senthil D, Ghosh Choudhury G, and Kasinath B. S. Stimulation of protein synthesis in mouse proximal tubular epithelial cells by VEGF: Potential relevance to diabetic nephropathy. Diabetes 52(Suppl. 1):A189, 2003.
    84. Simon M, Gorin Y, Bhandari B, Ghosh Choudhury G, Abboud HE. Tumor necrosis factor-α modulates the apoptotic effect of anti-Thy-1 antibody. Presented at TXSAN 2003, Austin, Texas, May 2-4, 2003.
    85. Gorin Y, Ricono JM, Kim N-H, Simon M, Bhandari B, Ghosh Choudhury G, Abboud HE. NOX4 mediates  angiotension  II-induced  mesangial  cell  hypertrophy  via activation of AKT/protein kinase B. Presented at TXSAN 2003, Austin, Texas, May 2-4, 2003.
    86. Wagner B, Ricono JM, Gorin Y, Ghosh Choudhury G, Abboud HE. Suppression of NADPH oxidase 4 inhibits PDGF-BB stimulated mitogenesis in metanephric mesenchymal cells.  Presented at TXSAN 2003, Austin, Texas, May 2-4, 2003.
    87. Wagner  B,  Ricono  JM,  Gorin  Y,  Ghosh  Choudhury  G,  Abboud  HE.      PDGFRβ- mediated PLC-γ activation inhibits Akt (PKB) and ERK1/2 phosphorylation in metanephric mesenchymal cells. Presented at the National  Kidney  Foundation Clinical Meetings, Dallas, TX,  April 2-6, 2003.
    88. Wagner B, Gorin Y, Ghosh Choudhury G, JM, and Abboud HE. Suppression of NAD(P)H Oxidase 4 Inhibits PDGF-BB Stimulated Mitogenesis in Metanephric Mesenchymal Cells. Journal of Investigative Medicine 51(Supplement 1):  S311, 2003.
    89. Ghosh Choudhury G. Tyrosine phosphorylation and phosphatidylinositol 3 kinase (PI 3-K)/Akt signal transduction regulate TGFβ-induced fibronectin gene expression in mesangial cells (MC). J. Am. Soc Nephrol. 13, Abs SA-PO232, p311A, 2002.
    90. Bhandari B., Duraisamy S., Ghosh Choudhury G. and Kasinath B. S. Regulation of renal cortical protein tyrosine phosphatases (PTP) in mice with type 2 diabetes. J. Am. Soc. Nephrol. 13, Abs SU-PO333, p535A, 2002.
    91. Duraisamy S., Ghosh Choudhury G., Bhandari B. and Kasinath B. S. Angiotensin II (Ang II) regulates expression of vascular endothelial growth factor (VEGF) and type 2 VEGF receptor (VEGFR2) in proximal tubular epithelial (PTE) cells. J. Am. Soc. Nephrol. 13, Abs SU-PO140. p496A, 2002.
    92. Duraisamy S., Ghosh Choudhury G. and Kasinath B.  S.  Protein  translation mechanism in VEGF sitmulated protein synthesis in renal proximal tubular epithelial (PTE) cells. J. Am. Soc Nephrol. 13 Abs Su-PO139, p496A, 2002.
    93. Gorin Y. C., Simon M., Bhandari B., Ghosh Choudhury G. and Abboud H. E. Tumor necrosis factor-alpha modulates the apoptotic effect of Thy 1.1 antibody. Role of PI 3 K/Akt/PKB-dependent NF-kB activation. J. Am Soc Nephrol. 13, Abs SU-PO169, p502A, 2002.
    94. Mahimainathan L. and Ghosh Choudhury G. Tumor suppressor PTEN  acts  as  a PDGF receptor phosphatase in mesangial  cells  (MC)  to  inactivate  mitogenic signaling. J. Am. Soc. Nephrol. 13, Abs F-PO972, p259A, 2002
    95. Ghosh-Choudhury N., Abboud S. L. and Ghosh Choudhury G. Recruitment of transcriptional co-activator CREB binding protein (CBP) during BMP-2-induced sitmulation of colony stimulating factor-1 (CSF-1) gene transcription: A role of BMP-2 in osteoclastogenesis. 4th  International Conference on Bone morphogenetic proteins. Sacramento, California. October 17-21, 2002.
    96. Bhandari B., Duraisamy S., Ghosh Choudhury G. and Kasinath B. S. Regulation of renal protein tyrosine phosphatase (PTP) in Type 2  diabetes.  Diabetes  51, Supplement 2, Abs 2586-PO, pA622, 2002.
    97. Duraisamy S., Ghosh Choudhury G and Kasinath B. S. Type 2 VEGF receptor (Flk- 1/KDR), recruits IRS-1 in its signaling pathway. Diabetes 51, Supplement 2  Abs 1866-P, pA454, 2002.
    98. Duraisamy S., Ghosh Choudhury G., Kasinath B. S. VEGF-regulation of protein synthesis in renal proximal tubular epithelial (PTE) cells.   Importance of initial steps in protein translation. Diabetes 51, Supplement 2 Abs 1865-P, pA454, 2002.
    99. Duraisamy S., Ghosh Choudhury G. and Kasinath B. S. Angiotensin II (Ang II) regulates expression of vascular endothelial growth factor (VEGF) and Type 2 VEGF receptor in proximal tubular epithelial (PTE) cells. Diabetes 51, Supplement 2, Abs 2579-PO, pA621, 2002.
    100. Ghosh-Choudhury N., Abboud S. L. and Ghosh Choudhury G. BMP-2-induced phosphatidylinositol 3 kinase (PI 3-K) regulates GATA-4 and MEF-2 transcription factors during cardiomyocyte differentiation. J Bone and Mineral Res.  17, Supplement 1, Abs SU045, p, S303, 2002.
    101. Ghosh Choudhury G. PI 3 kinase/Akt signaling cascade regulates TGFb-induced fibronectin expression in glomerular mesangial cells (MC). Keystone Symposia. Protein Phosphorylation and Mechanisms of Cellular Regulation. Abstract 302, p165, 2002.
    102. Duraisamy S., Ghosh Choudhury G. and Kasinath B. S. Type 2 VEGF receptor recruits IRS-1 in its signaling pathway. Keystone Symposia. Protein Phosphorylation and Mechanisms of Cellular Regulation. Abstract 116, p142, 2002.
    103. Duraisamy S., Faulkner J. L., Abboud H. E., Ghosh Choudhury G. and Kasinath B. S. Vascular endothelial growth factor (VEGF) control of protein synthesis and regulation of VEGF system by Angiotensin II  in  proximal  tubular  epithelial  (PTE) cells. J. Am. Soc. Nephrol. 12, Abstract A2942, p566A, 2001.
    104. Duraisamy S., Faulkner J. L., Abboud H. E., Ghosh Choudhury G. and Kasinath B. S. Vascular endothelial growth factor (VEGF) recruits insulin receptor substrate (IRS-1) in its signaling pathway. J. Am. Soc. Nephrol. 12, Abstract A3063, p589A, 2001.
    105. Ghosh Choudhury G. Phosphatidylinositol 3 kinase (PI 3-K) regulates EGF- induced c-fos gene transcription and DNA synthesis in mesangial cells (MC). J. Am. Soc. Nephrol. 12, Abstract A3056, p588A, 2001.
    106. Ghosh Choudhury G. PDGF-stimulated phosphatidylinositol 3 kinase (PI  3-K) target Akt regulates forkhead transcription factor and p27Kip1 cyclin kinase inhibitor gene transcription in mesangial cells (MC): Potential role in regulation of  PDGF- induced DNA synthesis. J. Am. Soc. Nephrol. 12, Abstract A3057, p588A, 2001.
    107. Ghosh Choudhury G., Abboud S. L., Qi W., Calhaun C., and Ghosh-Choudhury N. Requirement of phosphatidylinositol 3 kinase (PI 3-K) and Akt serine threonine kinase for bone morphogenetic protein-2 (BMP-2)-induced osteoblast diffferentiation.
      J. Am. Soc. Nephrol. 12, Abstract A3868, p741A, 2001.
    108. Riley D. J., Fred-Miranda I., Abboud H. E. and Ghosh Choudhury G. Bone morphogenetic protein 2 attenuates mesangioproliferative glomerulonephritis in rats. J. Am. Soc. Nephrol. 12, Abstract A3225, p620A, 2001.
    109. Ghosh-Choudhury N., Abboud S. L. and Ghosh  Choudhury  G. Phosphatidylinositol 3 kinase (PI 3-K) and Akt serine/threonine kinase regulates BMP-2-induced osteoblast differentiation and Smad-dependent transcription of BMP- 2 gene. J Bone Mineral Res 16, p, S144, 2001.
    110. Kim N.-H., Gorin Y., Kasinath B. S., Ghosh Choudhury G., Bhandari  B.  and Abboud H. E. Hypertrophy of cultured rat podocytes in response to high glucose and Angiotensin II. J. Am. Soc. Nephrol. 12, Abstract A4389, p839A, 2001.
    111. Senthil D., Faulkner J. L., Abboud H. E., Ghosh Choudhury G. and Kasinath B. S. IGF1 regulation of protein translation in  renal  proximal  tubular  epithelial  (PTE) cells. Abstract 1056-P, Diabetes 50, Supplement 2, page A257, 2001.
    112. Senthil D., Faulkner J. L., Ghosh Choudury G., Abboud H. E. and Kasinath B. S. Angiotensin II (AII) inhibits insulin-stimulated phosphorylation of eukaryotic initiation factor 4E (eIF4E) binding protein 1 (4EBP-1) in renal epithelial (PTE) cells. Abstract 1697-P, Diabetes 50, Supplement 2, page A408, 2001.
    113. Faulkner J. L., Gadre S., Senthil D., Abboud H. E., Ghosh Choudhury G. and Kasinath B. S. Activation of renal cortical PI 3 kinase, Akt (PKB) and Erk-1/2 type MAPK but not of p38 MAPK, is associated with renal hypertrophy in mice with type 1 diabetes. Abstract 706-P, Diabetes 50, Supplement 2, page A174, 2001.
    114. Senthil D., Faulkner J. L., Ghosh Choudhury G., Abboud H. E. and Kasinath B. S. Angiotensin II (AII)  inhibits  insulin-stimulated  phosphorylation  of  eukaryotic initiation factor 4E (e-IF4E) binding protein (4EBP1) in renal epithelial (PTE) cells. Keystone Symposia, Signaling Systems: Chemistry, Biology and Pathology. Abstract 113, p55, 2001.
    115. Senthil D., Faulkner J. L., Abboud H. E., Ghosh Choudhury G. and Kasinath B. S. IGF-1 stimulates eukaryotic initiation factor 4E (eiF4E) binding protein 4E-BP-1 phosphorylation in PTE cells. Keystone Symposia, Signaling Systems: Chemistry, Biology and Pathology. Abstract 211, p59, 2001.
    116. Ghosh Choudhury G. c-Src dependent phosphatidylinositol 3 kinase (PI 3 K) and Erk1/2  (MAPK)  regulate  PDGF-induced  DNA  synthesis  in  glomerular  mesangial cells. Keystone Symposia, Signaling Systems: Chemistry, Biology and Pathology. Abstract 209, p59, 2001.
    117. Faulkner J. L., Senthil D., Feliers D., Abboud H. E., Ghosh Choudhury G. and Kasinath B. S. Activation of renal cortical Akt (PKB) in db/db mice with type  II diabetes. J. Am. Soc. Nephrol. 11, Abstract A3373, p640A, 2000.
    118. Faulkner J. L., Senthil D., Abboud H. E., Ghosh Choudhury G. and Kasinath B. S. Increase in renal cortical Akt (PKB) and Erk-1 type MAP kinase activities is associated with renal hypertrophy in type I diabetes. J. Am. Soc. Nephrol.  11, Abstract A3372, p640A, 2000.
    119. Ghosh Choudhury G. and Calhaun C. c-Src tyrosine kinase regulates PDGF- induced mitogenic signaling in mesangial cells (MC) via regulation of Akt serine threonine kinase. J. Am. Soc. Nephrol. 11, Abstract A2313, p440A, 2000.
    120. Ghosh-Choudhury N., Ghosh Choudhury G., Woodruff K. A., Bsoul S., Nishimura R., Qi W., Celeste A. and Abboud S. L. Identification of a Smad-binding element (SBE) in BMP-2 responsive CSF-1 gene promoter: a mechanism of BMP-2-mediated transregulation of osteoclastogenesis during bone remodeling. J Bone Mineral Res 15, p, S203, 2000.
    121. Ghosh Choudhury G. Akt serine threonine kinase regulates PDGF-induced DNA synthesis and MAPK –dependent c-fos gene transcription in mesangial cells: Use of adenovirus mediated gene transfer. J. Am. Soc. Nephrol. 11, Abstract  A2266, p431A, 2000.
    122. Senthil D., Faulkner J. L., Ghosh Choudhury G., Abboud H. E. and Kasinath B.S. Angiotensin II (AII)  inhibits  insulin-stimulated  phosphorylation  of  eukaryotic initiation factor 4E (eIF4E) binding protein ` (4EBP-1) in mouse proximal tubular epithelial (PTE) cells: Cross talk between AII receptor and insulin receptor signal transduction. J. Am. Soc. Nephrol. 11, Abstract A2244, p427A, 2000.
    123. Senthil D., Faulkner J. L., Abbod H. E., Ghosh Choudhury G. and Kasinath B. S. IGF-I-stimulated eukaryotic initiation factor 4E (eIF4E) binding protein 4EBP-1 phosphorylation: Cross talk between PI 3 kinase and Erk-1 type MAP kinase pathways in mouse proximal tubular epithelial (PTE) cells. J. Am. Soc. Nephrol. 11, Abstract A2245, p427A, 2000.
    124. Gorin Y., Kim N.-H., Bsoul S., Feliers D., Zhang J.-H., Ghosh Choudhury G. and Abboud H.E. Induction of hypertrophy by angiotensin II in glomerular mesangial cells via an arachidonic acid and redox dependent pathway involving extracellular signal regulated protein kinase. J. Am. Soc. Nephrol. 11, Abstract A2271, p432A, 2000.
    125. Ricono J. M., Zheng B.X., Ghosh Choudhury G., Soriano P. and Abboud H. E. Differential effect of PDGF AA and BB on migration of metanephric mesenchymal cells (MMC): Role of calcium. J. Am. Soc.  Nephrol.  11,  Abstract  A1998,  p318A, 2000.
    126. Senthil  D.,          Bhandari B. K., Feliers D., Faulkner J .L. Ghosh Choudhury G., Abboud H. E. and Kasinath B. S. PI 3 kinase and mTOR are required for insulin induced phosphorylation of eukaryotic initiation factor 4E binding protein 1 (4EBP1) in proximal tubular epithelial (PTE) cells. Diabetes 49, Supplement 1, Abstract 1400- P, page A334, 2000.
    127. Feliers D., Faulkner J. L., Senthil D. Lee A. V., Abboud H. E., Ghosh Choudhury G. and Kasinath B. S. Regulation of PI 3 kinase, Akt and MAP kinase pathways in the kidney and liver of db/db mice with type 2 diabetes. Diabetes 49, Supplement 1, Abstract 634-P, page A155, 2000.
    128. Faulkner J. L., Felers D., Senthil D., Ghosh Choudhury G., Abboud H. E. and Kasinath B. S. Renal cortical Akt (PKB) kinase activation in db/db mice with type 2 diabetes. Diabetes 49, Supplement 1, Abstract 633-P, page A154, 2000.
    129. Ghosh-Choudhury N., Abboud S. L. and Ghosh  Choudhury G. Mechanism for Inhibitory Role of BMP-2 on Growth of Estrogen-responsive and Non-responsive Human Breast Cancer Cells. International Symposium on BMPs. 2000.
    130. Feliers D., Stewert J. L., Lee A. V., Abboud H. E., Ghosh Choudhury G. and Kasinath B. S. Activation of renal signaling pathways in type II diabetes. J. Am. Soc. Nephrol. 10, Abstract A3442, p679A, 1999.
    131. Ghosh Choudhury G., Kyomoto H. and Abboud H. E. Activation of PDGF receptor β (PDGFR) induces PI 3 kinase and MAPK in Thy-1-induced mesangioproliferative glomerulonephritis in rats. J. Am. Soc. Nephrol. 10, Abstract 3327, p656A, 1999.
    132. Bhandari B., Feliers D., Stewart J. L., Ghosh Choudhury G., Abboud H. E., and Kasinath B. S. Insulin induced phosphorylation of a protein translation repressor, 4EBP1, in proximal tubular epithelial (PTE) cells is dependent on PI 3 kinase and mTOR activation. J. Am. Soc. Nephrol., 10, Abstract A3424, p675A, 1999.
    133. Gorin, Y. Feliers D., Eakes A. T., Ghosh Choudhury G. and Abboud H. E. Angiotensin II-induced activation of Akt/protein kinase B serine/threonine kinase in mesangial cells: Involvement of phosphoinositide 3-kinase-independent and redox- dependent mechanisms. J. Am. Soc. Nephrol. 10, Abstract A2364, p468A, 1999.
    134. Gilroy J., Zheng B., Ghosh Choudhury G., Arar M. and Abboud H. E. Signaling of PDGF isoforms in PDGFβ receptor deficient metanephric mesenchymal cells (MMC). J. Am. Soc. Nephrol. 10, Abstract 2039, p404A, 1999.
    135. Arar M., Gonzalez M., Gilroy J., Bunegin M., Ghosh Choudhury G. and Abboud H. E. Effect of fibronectin on tubulogenesis. J. Am. Soc.  Nephrol.  10,  Abstract A2026, p402A, 1999.
    136. Ghosh Choudhury G.  and Gilroy J.  Synergistic action of  interferonγ (IFNγ) on PDGF-induced DNA synthesis is mediated via c-fos gene transcription in mesangial cells. J.  Am. Soc. Nephrol. 10, Abstract A2470, p489A, 1999.
    137. Ghosh Choudhury G., Jin D.-C., Kim Y.-S., Celeste A., Ghosh-Choudhury N. and Abboud H. E. Bone morphogenetic protein 2 (BMP-2) inhibits EGF-induced DNA synthesis    in    mesangial    cells    (MC)    via    blocking    MAPK-dependent    Elk-1 transactivation     and    by    increasing     p21    cyclin    kinase    inhibitor    transcription respectively. J. Am. Soc. Nephrol. 10, Abstract A2391, p473A, 1999.
    138. Ghosh Choudhury G. MAPK regulates EGF-induced DNA synthesis via Elk-1- dependent transcription in mesangial cells (MC). J. Am. Soc. Nephrol. 10, Abstract A2392, p474A,, 1999.
    139. Gorin Y.C., Feliers D., Eakes A.T., Ghosh Choudhury G. and Abboud H.E. Activation of ERK by angiotensin II in glomerular mesangial cells occurs via an arachidonic acid– and redox-dependent pathways. Mol. Biol Cell. 10 (Supplement) Abs 2430, p420a, 1999.
    140. Ghosh-Choudhury N., Ghosh Choudhury G., Besoul S., Woodruff K. A. and Abboud S. L. Regulation of CSF-1 gene transcription by BMP-2 during osteoblast differentiation: Mapping of BMP-2 responsive element. J. Bone and Mineral Res. 10, Supplement 1, Abstract SU008, pS433, 1999.
    141. Ghosh-Choudhury N., Abboud S. L. and Ghosh Choudhury G. BMP-2 inhibits EGF-induced MDA-MB-231 breast cancer cell growth via increased expression of p21WAF1 cyclin kinase inhibitor (CKI). J. Bone and Mineral Res. 10, Supplement 1, Abstract SA054, pS322, 1999.
    142. Abboud S. L., Woodruff K., Ghosh Choudhury G. and Ghosh-Choudhury N. CSF- 1/lacZ transgenic mice, a model for mapping CSF-1 expression during murine embryogenesis. J. Bone and Mineral Res. 10, Supplement 1, Abstract  SA159, pS348, 1999.
    143. Kasinath B. S., Feliers D., Stewart J. L., H. E. Abboud and Ghosh Choudhury G. Activation of PI 3 kinase and MAP kinase pathways in the kidney of mice with type II diabetes. Abstract 143, Specificity in Signal Transduction. Keystone Symposia, April 9-14, 1999, Keystone, Colorado.
    144. Gorin Y., Feliers D., Eakes T. A., Ghosh Choudhury G. and Abboud H. E. Oxidative stress in glomerular mesangial cells: Activation  of  Erk  kinase  by angiotensin II in cells occurs via a redox-dependent pathway. Abstract 2035, Specificity in Signal Transduction. Keystone Symposia, April 9-14, 1999, Keystone, Colorado.
    145. Ghosh Choudhury G., Jin D.-C., Kim Y.-S., Celeste A., Ghosh-Choudhury N. and Abboud H. E. Bone morphogenetic protein 2 (BMP-2) inhibits EGF-induced DNA synthesis in glomerular mesangial cells (MC) by blocking MAPK-dependent Elk-1- mediated transcription. Abstract 128, Specificity in Signal Transduction. Keystone Symposia, April 9-14, 1999, Keystone, Colorado.
    146. Eakes AT., Abboud H. E. and Ghosh Choudhury G. Stimulation of Akt kinase by interferonγ and PDGF in cultured mesangial cells. Mol Biol. Cell 9, Abstract 2085, 1998.
    147. Gilroy J. M., Arar M. Nishihara F., Jin D. C., Ghosh Choudhury G. and Abboud H. E. Differential mitogenic signaling of platelet-derived growth factor (PDGF) isoforms in metanephric mesenchymal cells (MMC): Activation of phosphatidylinositol 3 kinas (PI 3K) and  mitogen activated protein kinase (MAPK). Mol Biol. Cell 9,     Abstract 1820, 1998.
    148. Ghosh-Choudhury N., Celeste A., Harris S. E. and Ghosh Choudhury G. Bone morphogenetic protein 2 (BMP-2)-induced osteoblast cell proliferation is mediated by mitogen-activated protein kinase (MAPK)-dependent c-fos gene transcription. Bone 22 Abstract S012, ppS415, 1998.
    149. Ghosh-Choudhury N., Ghosh Choudhury G., Celeste A., Ghosh P., Stapleton M. and Kreisberg J. Bone morphogenetic protein 2 blocks estrogen-induced  human breast cancer cell growth by intercepting mitogen activated protein kinase (MAPK)- dependent nuclear signals. Bone 22 Abstract 1076, ppS167, 1998.
    150. Abboud S. L., Woodruff K. and Ghosh Choudhury G. Putative cis-acting elements in the 5’ flanking region of  the  CSF-1  promoter  involved  in  cell-specific gene expression of CSF-1. Bone 22 Abstract Fo39, pp S421, 1998.
    151. Abboud S. L., Woodruff K. and Ghosh Choudhury G. Potential cis-acting elements in the 5’ flanking region of the IGFBP5 promoter required for basal promoter activity in stromal cells and osteoblasts. Bone 22 Abstract SA135, pp S560, 1998.
    152. Duch J. M., Lee A., Stewart J. L., Ghosh Choudhury G. and Kasinath B. S. Activation of signaling pathways in the renal cortex of db/db mice with type II diabetes. Am. Soc. of Nephrol. 9, Abstract A3222, pp631A, 1998.
    153. Ghosh Choudhury G. and Abboud H. E. PDGF-induced serine phosphorylation of STAT1a regulates its transcriptional activity in mesangial cells (MC). Am. Soc. of Nephrol. 9,  abstract A2032, pp398A, 1998
    154. Ghosh Choudhury G., Kim Y.-S., Simon M., Ghosh-Choudhury N., Wozney J., Harris H. and Abboud H. E. Antagonism of PDGF receptor -induced mitogenesis by bone morphogenetic protein 2 in glomerular mesangial cells: Interception of mitogen- activated protein kinase dependent c-fos gene expression. International Society of nephrology forefronts in Nephrology symposium, June 13-16, 1998, Grand Teton National  Park,Wyoming.
    155. Feliers D., Grandaliano G., Wenzel U., Valente A., Ghosh Choudhury G.  and Abboud H. E. PDGF stimulates MCP-1 transcription in rat mesangial cells FASEB J. Abs. 2514, Abstracts Part I, 1998.
    156. Ghosh  Choudhury  G,  Sylvia  V,  Harvey  S.  and  Sakaguchi  AY.             Decline of receptor mediated second messenger pathway in IMR90 diploid fibroblast high population doublings. D116, J. Cell. Biochem., Supplement 15B,1991.
    157. Ghosh Choudhury G., Grandaliano G., Gilroy J. and Abboud H. E. Protein kinase C regulates PDGF-induced STAT1α  activation  in  glomerular  mesangial  cells. Abstract 320, Specificity in Signal Transduction. Keystone  Symposia,  March  1-7, 1998 Lake Tahoe, Nevada.
    158. Bardgette J., Abboud H. E., Yee J., Woodruff K., Abboud S. L. and Ghosh Choudhury G. Retroviral mediated gene transfer of angiotensin II (AII) receptor type I into glomerular mesangial cells (MC): Studies on cell hypertrophy. J. am. Soc. Nephrol. 8, p398A, 1997.
    159. Ghosh Choudhury G. Kim Y.-S., Bardgette J., Ghosh-Choudhury N., Wozney J., Harris S. and Abboud H. E. Bone morphogenetic protein 2 (BMP2) inhibits PDGF- induced c-fos gene transcription in a PI 3 kinase and MAPK  dependent  manner leading to inhibition of mitogenesis in mesangial cells (MC). J. Am. Soc. Nephrol. 8, p435A, 1997.
    160. Ghosh Choudhury G. Kim Y.-S., Simon M., Wozney J., Harris S and Abboud H. E. Bone morphogenetic protein 2 (BMP2) inhibits human glomerular mesangial cell (MC) growth: Negative regulation by protein kinase Cα. 2nd International Conference on Bone morphogenetic proteins. June 4-8,  1997, Sacramento, California.
    161. Abboud S. L., Woodruff K. A. and  Ghosh  Choudhury  G.  Retrovirus-mediated gene       transfer of CSF-1 into op/op stromal cells to correct defective osteoclastogenesis. J. Bone and Mineral Res. 11, Supplement 1, p, S97.
    162. Ghosh Choudhury G. Marra F. and Abboud H.E. Interferon γ-stimulated STAT1α regulates receptor tyrosine kinase mediated DNA synthesis in glomerular mesangial cells. Mol. Biol. of the Cell 7, p353a. 1996.
    163. Simon, M. A. Uttomo, Ghosh Choudhury G. and H.E. Abboud. Effects of Shiga- like toxin (SLT-1) on human mesangial cells J. Am Soc. Nephrol. 7: 1746, 1996.
    164. Park. J.Yee., Ghosh Choudhury G., Kiyomoto, H., Lianos E., and Abboud HE. Differential expression of plasminogen activator inhibitor 1 (PAI-1), urokinase type plasminogen activator (uPA) and matrix metalloproteinase 2 (MMP-2) in mesangioproliferative glomerulonephritis (MesGN) in rats. I. J. Am. Soc. Nephrol. 7: p1743. 1996.
    165. Bardgette J., Abboud H.E., Wenzel U.O. and Ghosh Choudhury G. Protein tyrosine phosphatases regulateSTAT1 in cultured mesangial cells. J. Am. Soc. Nephrol. 7: p1670, 1996.
    166. Ghosh    Choudhury    G.,          Gentilini    A.,    Karamitsos     C.    and    Abboud    H.E. Phosphatidylinositol 3 kinase (PI3 K) and protein kinase Cα (PKCα) regulate human mesangial cell (MC) migration in response to platelet-derived growth factor (PDGF). J. Am. Soc. Nephrol. 7: p1656 1996.
    167. Ghosh Choudhury G. and Abboud H.E. Direct activation of STAT1 by platelet- derived growth factor receptor (PDGFR) in mesangial cells (MC) J. Am. Soc. Nephrol. 7: p 1656, 1996.
    168. Arar M., Elshihabi I., Ghosh Choudhury G. Gentilini A. and Abboud H.E. Effect of platelet-derived growth factor B-chain on glomerulogenesis. J. Am. Soc. Nephrol. 7: p1593, 1996.
    169. Ghosh    Choudhury    G.,          Karamitsos     C.,    Gentilini    A.    and    Abboud    H.E. Phosphatidylinositol 3 kinase regulates glomerular mesangial cell chemotaxis and proliferation: Involvement of mitogen activated protein kinase dependent and independent pathways. FASEB J. 10: P50, 1996.
    170. Ghosh Choudhury G., Marra F. and Abboud H.E. Association of the SH2-SH3- domain-containing adaptor protein Nck with focal adhesion kinase in thrombin- stimulated mesangial cells. J. Am. Soc. Nephrol. 6, p 786, 1995.
    171. Wenzel U.O., Bhandari B., Ghosh Choudhury G.,  Valente A.J. and Abboud H.E. A reporter mesangial cell line transfected with a monocyte chemoattractant protein 1 (MCP-1) promoter. Transcriptional activation  by  thrombin. J. Am. Soc. Nephrol. 6, p858, 1995.
    172. Ghosh Choudhury G., Marra F. and Abboud H.E. Platelet-derived growth factor (PDGF) stimulates tyrosine phosphorylation of Janus kinase 1 (JAK 1) protein tyrosine kinase in human mesangial cells (MC). J. Am. Soc. Nephrol.  6, p 765, 1995.
    173. Kiyomoto H., Park I.S., Ghosh Choudhury G. and Abboud H.E. Stimulation of mitogen activated protein kinase (MAPK) and suppression of protein tyrosine phosphatase (PTPase) in experimental proliferative glomerulonephritis. J. Am. Soc. Nephrol.  6, p 872, 1995.
    174. Ghosh Choudhury G., Marra F. and Abboud H.E. Association of the SH2-SH3 domain containing adaptor protein Nck with a tyrosine phosphorylated protein p125 in thrombin-stimulated mesangial cell. Proc. Am. Association of Cancer Research 36,Abs 324. P, 54. 1995.
    175. Ghosh Choudhury G., Marra, F., Karmitsos, C., Kiyomoto, H. and Abboud, H.E. Inhibition of phosphatidylinositol 3 kinase (PI 3 kinase) activity blocks PDGF-induced DNA synthesis in glomerular mesangial cells.  J.  Cell.  Biochem.  Supplement  19A Abs. A130, p 16, 1995.
    176. Kiyomoto  H,  Abboud  HE,  Fouqueray  B,  and  Ghosh  Choudhury  G.            Phorbol myristate acetate (PMA)-induced inhibition of the cytoplasmic tyrosine phosphatase PTP1B enhances tyrosine phosphorylation in human mesangial cells (HMC). J. Am. Soc. Nephrol. 5, p. 719, 1994.
    177. Kiyomoto H, Ghosh Choudhury G, Fouqueray B, and Abboud HE. Activation of glomerular  phosphotyrosine  phosphatase  in  streptozotocine-induced  diabetes (STZD) in the rat.  J. Am. Soc. Nephrol. 5, p. 967, 1994.
    178. Kasinath BS, Grellier P, Terhune WC, Maldonado R, Ghosh Choudhury G, and Abboud SL. High glucose medium reduces glomerular basement membrane (GBM) heparan sulphate proteoglycan (HSPG) core protein gene expression in glomerular epithelial cells.  J. Am. Soc.Nephrol. 5, p. 967, 1994.
    179. Ghosh Choudhury G, and Abboud HE. Vanadate activates phosphatidylinositol 3 kinase (PIβ 3 kinase) via enhanced tyrosine phosphorylation of platelet-derived growth factor receptor β (PDGFRβ) in human mesangial cells (HMC). J. Am. Soc. Nephrol 5, p. 690, 1994.
    180. Ghosh  Choudhury  G,  Grandaliano  G,  Biswas  P  and  Abboud  HE. Signal transduction   of   thrombin   involves   phosphatidylinositol   3   kinase   (PI   3   kinase) activation in human glomerular mesangial cells. J Cell Biochem Abs.   Supplement 18B, Abs I217, p, 235, 1994.
    181. Fourqueray  B,  Kiyomoto  H,  Ghosh  Choudhury  G,  and  Abboud  HE. Glucose modulates tyrosine phosphatase activity in cultured mesangial cells.  Clin Res, 1994.
    182. Biswas P, Ghosh Choudhury G, Wenzel U, Grandaliano G and Abboud HE. Differential effect of thrombin on protein kinase C isoforms in mesangial  cells. Clinical Res 42:144A , 1994.
    183. Kasinath BS, Grellier P, Terhune WC, Ghosh Choudhury G., Maldonado R,and Abboud SL. Regulation of basement membrane (BM) heparansulphate proteoglycan (HSPG) core protein gene expression by high glucose medium in glomerular epithelial cells (GEC).  Clinical Res 43:143A, 1994.
    184. Ghosh Choudhury G, Grandaliano G, and Abboud HE. Differential activation of PDGF-receptor subunits by homo- and heterodimeric forms of PDGF. J Am  Soc Nephrol 4: 463, 1993.
    185. Biswas  P,  Ghosh  Choudhury  G,  Grandaliano  G,  and  Abboud  HE.  Thrombin stimulates DNA synthesis and PDGF B chain mRNA expression via different signaling pathways in human mesangial cells.  J Am Soc Nephrol 4: 482, 1993.
    186. Kiyomoto H.,Biswas P, Ghosh Choudhury G, and Abboud HE. Activation of renal protein kinase C isoforms in streptozotocin-induced diabetes (STZD). J  Am  Soc Nephrol 4: 797, 1993.
    187. Wenzel U, Grandaliano G, Fouqueray B, Ghosh Choudhury G,and Abboud HE. Vanadate induces mitogenesis and platelet-derived growth factor B-chain gene expression in human mesangial cells. J Am Soc Nephrol 4: 808, 1993.
    188. Grandaliano  G,  Ghosh  Choudhury  G,  Biswas  P,  and  Abboud  HE. Mitogenic signaling of thrombin in mesangial cells: role of tyrosine phosphorylation. J Am Soc Nephrol 4: 486, 1993.
    189. Fouqueray B, Ghosh Choudhury G, Grandaliano G, Biswas P, Wenzel U, and Abboud HE. Involvement of protein tyrosine phosphatases in human mesangial cell early signaling.  J Am Soc Nephrol 4: 486, 1993.
    190. Ghosh Choudhury G, Biswas P, and Abboud HE. Platelet-derived growth factor homo- and heterodimers stimulate phosphatidylinositol 3 kinase in human glomerular mesangial cells. J Cell Biochem Suppl. 17A:233, 1993.
    191. Ghosh Choudhury G, Biswas  P,  Grandaliano  G,  and  Abboud  HE.Thrombin- mediated Mitogenic signaling involves protein kinase C alpha (PKCa) in human glomerular mesangial cells.  FASEB J 7:332, 1993.
    192. Grandaliano G, Biswas P, Ghosh Choudhury G, Barnes JL,  and  Abboud  HE. PGE1 analog misoprostal inhibits thrombin-induced DNA synthesis  and  PDGF  B- chain expression in cultured human mesangial cells. Clin Res 41:141A, 1993.
    193. Biswas  P,  Ghosh  Choudhury  G,  Grandaliano  G,  and  Abboud  HE. Platelet- derived growth factor (PDGF)-induced mitogenesis involves activation of protein kinase Cα (PKCα) in human glomerular mesangial cells (HMC). J Am Soc Nephrol 3:463, 1992.
    194. Ghosh    Choudhury    G.,Biswas     P,    and    Abboud     HE. Activation     of phosphatidylinositol 3 kinase in human mesangial cells in response to platelet- derived growth factor.  J Am Soc Nephrol  3:489, 1992.
    195. Ghosh  Choudhury  G.,  Sylvia  V,  and  Sakaguchi  AY.  Involvement of tyrosine phosphorylation and a G-protein in the activation of human colony stimulating factor- 1 receptor. Abs H 318, in J Cell Biochem. Supplement 16B, 209, 1992.
    196. Sakaguchi AY, Seldin MF, Martinez L, Lalley PA, Han ES, Ghosh Choudhury G, and Smith EA. Subregional localization of  mouse  platelet  derived  growth  factor alpha and beta genes. Abs. 27429, in Eleventh International Workshop on Human Gene Mapping, p, 301, 1991.
    197. Sakaguchi AY, Martinez L, Lalley PA, Sylvia VL, Han ES, Killary AM, and Ghosh Choudhury   G.      Chromosome mapping in mouse of genes that regulate the eukaryotic cell cycle. Abs. 27428, in  Eleventh  International Workshop  on  Human Gene Mapping, p, 301, 1991.
    198. Sakaguchi AY, Sylvia VL, Martinez L, Lalley PA, Shows TB, Han ES, Smith EA, and Ghosh Choudhury G. Assignment of Tyrosine specific T-cell phosphatase to conserved syntenic groups on human chromosome 18 and mouse chromosome 18. Abs. 27427, in Eleventh International Workshop on Human Gene Mapping, p, 174, 1991.
    199. Ghosh Choudhury G, Wang LM, Sylvia V, Martinez L, and Sakaguchi AY. Human colony stimulating factor-1 receptor activates two potential signal  transducing molecules. Texas Genetics Society 17th Annual Meeting, Austin, Texas, March 23, 1990.
    200. Sakaguchi AY, Seldin MF, Martinez L, Watson M, Lalley PA, Ghosh Choudhury G, Pierce J, Aaronson S, Naylor SL, and Smith EA. The mouse platelet-derived growth factor-receptor A gene is closely linked to kit and is encompassed by the W19H chromosome 5 deletion. Abs 50, in Growth Factors and their receptors in Cancer: Basic mechanism and therapy. In Fortythird Annual Symposium on Fundamental Cancer research, 1990.
    201. Sylvia V, Ghosh Choudhury G, Fernandes G, Lee BK, and  Sakaguchi  AY. Colony Stimulating Factor-1 Receptor-mediated signal transduction in macrophages declines with age. Abs 58, in Growth Factors and their receptors in Cancer: Basic mechanism and therapy. In Fourtythird Annual symposium on Fundamental Cancer Research, 1990.
    202. Ghosh  Choudhury  G,  Wang  LM,  Martinez  L,  and  Sakaguchi  AY.CSF-1 stimulates association of its receptor with phosphatidylinositol kinase. J. Cell. Biochem. Supplement 14B:F211, 1990.
    203. Ghosh Choudhury G, Sylvia V, Harvey S, and Sakaguchi AY. Dysregulation of serum induced signal transduction in aging fibroblast. Abs. 9 in Growth factors and their receptors in Cancer: Basic mechanism and therapy. In Fourtythird Annual Symposium on Fundamental Cancer Research, 1990.
    204. Ghosh Choudhury G, Wang LM, Martinez L, Han ES and Sakaguchi AY. Human colony stimulating factor 1 receptor associates with a phosphatidylinositol kinase: A mutational analysis.  Human Genetics 45:059, 1989.

    Goutam Ghosh Choudhury

    Professor

     

    • :210-567-4830
      Fax :210-567-4712
    • DEPARTMENTDepartment  of  Medicine,
      Division of Nephrology
      University  of  Texas  Health Science Center at San Antonio
    • COUNTRY USA