Tomas Hanke
Professor
- E-mail:tomas.hanke@ndm.ox.ac.uk
- DEPARTMENTDepartment of Medicine
University of Oxford
- COUNTRYUK
ACADEMIC AWARDS / DISTINCTIONS
1998 MRC Career Track Scientist, Band 3
2003 MRC Career Scientist, Band 2
2003 Research Lecturer, UOXF
2008 Reader in Immunology, UOXF
2008 Hoc Vien Quan Y Viet Nam (Medal), Vietnam Military Medical University
2009 Jenner Institute Investigator
2010 Professor of Vaccine Immunology, UOXF
GRANTS
EC H2020 BIOTEC 1 - 2014 (PI: Hanke, Schänzler and Šlais) under review
Development of scalable manufacturing processes and GMP manufacture for vaccine vectors of simian adenovirus and poxvirus origin carrying synthetic pathogen-derived transgenes.
(7.2M EUR)
EDCTP/ BMGF + IAVI (2012-2015)(PI: Hanke, Jaoko and Reilly)SP.2011.41304.002
A phase I/IIa clinical trial of universal HIV-1 vaccines pSG2.HIVconsv, MVA.HIVconsv and ChAdV63.HIVconsv in combined regimens in healthy HIV-1/2-negative adults in Nairobi.
(800k + 400k EUR)
EC FP7 (2013-2017)(PI: Dorrell, Barnes, Hanke and 3 others) 305632
Prevention of hepatitis C (HCV) and HIV-1 infections through induction of potent T cell responses using prime-boost viral vector vaccine regimens. (7M EUR)
MRC UK DCS (2012-2015) (PI: Pepys, Hanke and 2 others) MR/J008605/1
Depletion of serum amyloid P component to enhance the immune response to DNA. vaccination (1.2M GBP)
MRC UK Programme grant (2011-2016) (PI:Hanke, Kessler, McMichael and Hill) G100175
A universal T cell vaccine for HIV-1 (1.2M GBP)
MRC UK Exp Med II (2008-2012) (PI: Hanke and Dorrell) G0701669
Development of a universal HIV-1 vaccine (1.3M GBP)
MRC UK Industrial Studentship (2008-2012) (PI: Hanke and Cranenburgh)
Pre-clinical development of a universal HIV-1 vaccine preventing mother-to-child transmission of HIV-1 through breastfeeding (60k GBP)
EDCTP/BMGF (2008-2012) (PI:Hanke and 5 others) CT.2006.33111.002
Building capacity of Infant HIV-1 Vaccine Clinical Trial Centres in Nairobi, Kenya and Fajara, The Gambia (3M EUR)
Japan Health Science Foundation (2007-2011) (PI:Takiguchi, Hanke and 2 others)
Development of therapeutic HIV -1 vaccine (4x7M JPY)
MCR UK Unit Award (1998-2010, 2010-2012) (PI: Hanke)MC_U137884179, G1000800d
HIV-1 vaccine development(80k pa + 800k GBP for non-human primates)
Japanese AIDS Foundation (2005-2006) (PI: Takiguchi, Hanke and 2 others)
Development of an MVA-vectored therapeutic HIV-1 vaccine (5M JPY)
International AIDS Vaccine Initiative (1998-2005) (PI :McMichael, Bwayo, Hanke)
AIDS Vaccine UK-Kenya Partnership (6M USD)
EC FP5 (1999-2002, 2003) (20 investigators)
European Vaccine Effort Against HIV/AIDS (EuroVacc) (8M EUR)
WHO Grant (1999-2000) (Hanke and 2 other investigators)
Vaccination against HIV using live mycobacterial vectors
NATO Collaborative Research Grant (1996-1998) (PI: Hanke)
DNA immunization/protection experiment in macaques: role of CTL
SUPERVISION OF GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS
1998–now 13 Post-docs/ 12 D.Phil./ 12 M.Sc. Students, NDM, UOXF / Wageningen Univ, NL
INSTITUTIONALRESPONSIBILITIES
2011 - now Advisor to starting PIs
2005- now Management Committee, The Jenner Institute, UOXF, UK
2005 - now Management Committee, Clinical Manufacturing Facility, UOXF, UK
2000- 2001 OrganizerofInternalSeminars, MRC Human Immunology Unit, UOXF, UK
2001 - 2010 Biological Safety Committee, Weatherall Inst. of Molecular Medicine, UOXF, UK
COMMISSIONS OF TRUST
2014 HIV Vaccine Industry Think Tank, Global HIV Vaccine Enterprise, NY, USA
2012-2014 European and Developing Countries Clinical Trial Partnership (EDCTP)
Stakeholders meetings
2010, 2014 National Research Foundation / MRC, South Africa
2011 - 2012 Health and Medical Research Fund, Hong Kong
2008 - 2012 Infection and Immunity Research Board (IIB), MRC UK
2004,2005,2007-2010 NIH NIAID Special Emphasis Panel
2007 EMEA European Expert
2007 MRC IIB – Translational Vaccine Research call
2006, 2007, 2009 Research Council of Norway
2005-2008 MRC College of Experts, Infections and Immunity Board
2004, 2005, 2014 South African AIDS Vaccine Initiative
2005 Site Visit team for the NCI Vaccine Branch, NIH
2003-2004 Advisory Board, MRC UK
2002-2005 Ethical Review Panel for the MRC Centre for Macaques
2000 MRC UK AIDS Vaccine Advisory Subcommittee
2006 Editorial board, Future HIV Therapy
2003 Editorial board, Genetic Vaccines and Therapy
2001 Editorial board, Current Molecular Medicine
2011 Editorial board, Future Virology
MEMBERSHIPSOFSCIENTIFICSOCIETIES
British Society for Immunology, American Society of Gene & Cell Therapy
MAJOR COLLABORATORS
Dr Lucy Dorrell, Prof Sir Andrew McMichael and Dr Benedikt Kessler, University of Oxford; Wayne Koff, Thomas Hassell, Pat Fast, Christopher Parks et al., The International AIDS Vaccine Initiative; Prof Walter Jaoko, University of Nairobi, Kenya; Dr Bette Korber, Los Alamos National Laboratory, USA; Prof John Moore, Cornell University; Dr Katie Flanagan, formerly MRC Laboratories, The Gambia; Prof Grace John-Stewart, University of Washington, USA; Profs Marie Reilly and Peter Liljeström, Karolinska Institute, Sweden; Prof Sir Mark Pepys, University College London; Prof Christian Brander and Dr Beatriz Mothe, Irsicaixa AIDS Research Institute HIVACAT, Spain; Dr Sarah Fidler, Imperial College London and Dr Joan Joseph, Hospital Clinic Barcelona, Spain; Drs Jerald Sadoff and John Fulkerson, Aeras Global TB Vaccine Foundation, USA; Prof Masafumi Takiguchi University of Kumamoto, Japan; Prof David Watkins, University of Wisconsin; Dr Rocky Cranenburgh, Cobra Biomanufacturing, recently RecipharmCobra Biologics,UK; Profs Mary Jane Potash, David Volsky, University of Columbia; USA, Prof Cornelis Melief, Leiden University Medical Centre, The Netherlands and others.
Professor