Professional Activities

ACADEMIC AWARDS / DISTINCTIONS
1998                    MRC Career Track Scientist, Band 3
2003                    MRC Career Scientist, Band 2
2003                    Research Lecturer, UOXF
2008                    Reader in Immunology, UOXF
2008                    Hoc Vien Quan Y Viet Nam (Medal), Vietnam Military Medical University
2009                    Jenner Institute Investigator
2010                    Professor of Vaccine Immunology, UOXF

GRANTS
EC H2020 BIOTEC 1 - 2014 (PI: Hanke, Schänzler and Šlais) under review
Development of scalable manufacturing processes and GMP manufacture for vaccine vectors of simian adenovirus and poxvirus origin carrying synthetic pathogen-derived transgenes.
(7.2M EUR)
EDCTP/ BMGF + IAVI (2012-2015)(PI: Hanke, Jaoko and Reilly)SP.2011.41304.002
A phase I/IIa clinical trial of universal HIV-1 vaccines pSG2.HIVconsv, MVA.HIVconsv and ChAdV63.HIVconsv in combined regimens in healthy HIV-1/2-negative adults in Nairobi.
(800k + 400k EUR)
EC FP7 (2013-2017)(PI: Dorrell, Barnes, Hanke and 3 others) 305632
Prevention of hepatitis C (HCV) and HIV-1 infections through induction of potent T cell responses using prime-boost viral vector vaccine regimens. (7M EUR)
MRC UK DCS (2012-2015) (PI: Pepys, Hanke and 2 others) MR/J008605/1
Depletion of serum amyloid P component to enhance the immune response to DNA. vaccination          (1.2M GBP)
MRC UK Programme grant (2011-2016) (PI:Hanke, Kessler, McMichael and Hill) G100175
A universal T cell vaccine for HIV-1 (1.2M GBP)
MRC UK Exp Med II (2008-2012) (PI: Hanke and Dorrell) G0701669
Development of a universal HIV-1 vaccine (1.3M GBP)
MRC UK Industrial Studentship (2008-2012) (PI: Hanke and Cranenburgh)
Pre-clinical development of a universal HIV-1 vaccine preventing mother-to-child transmission of HIV-1 through breastfeeding (60k GBP)
EDCTP/BMGF (2008-2012) (PI:Hanke and 5 others) CT.2006.33111.002
Building capacity of Infant HIV-1 Vaccine Clinical Trial Centres in Nairobi, Kenya and Fajara, The Gambia (3M EUR)
Japan Health Science Foundation (2007-2011) (PI:Takiguchi, Hanke and 2 others)
Development of therapeutic HIV -1 vaccine (4x7M JPY)
MCR UK Unit Award (1998-2010, 2010-2012) (PI: Hanke)MC_U137884179, G1000800d
HIV-1 vaccine development(80k pa + 800k GBP for non-human primates)
Japanese AIDS Foundation (2005-2006) (PI: Takiguchi, Hanke and 2 others)
Development of an MVA-vectored therapeutic HIV-1 vaccine (5M JPY)
International AIDS Vaccine Initiative  (1998-2005) (PI :McMichael, Bwayo, Hanke)
AIDS Vaccine UK-Kenya Partnership (6M USD)
EC FP5 (1999-2002, 2003) (20 investigators)
European Vaccine Effort Against HIV/AIDS (EuroVacc) (8M EUR)
WHO Grant (1999-2000) (Hanke and 2 other investigators)
Vaccination against HIV using live mycobacterial vectors
NATO Collaborative Research Grant (1996-1998) (PI: Hanke)
DNA immunization/protection experiment in macaques: role of CTL

SUPERVISION OF GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS
1998–now       13 Post-docs/ 12 D.Phil./ 12 M.Sc. Students, NDM, UOXF / Wageningen Univ, NL

INSTITUTIONALRESPONSIBILITIES
2011 - now      Advisor to starting PIs
2005- now       Management Committee, The Jenner Institute, UOXF, UK
2005 - now      Management Committee, Clinical Manufacturing Facility, UOXF, UK
2000- 2001      OrganizerofInternalSeminars, MRC Human Immunology Unit, UOXF, UK
2001 - 2010     Biological Safety Committee, Weatherall Inst. of Molecular Medicine, UOXF, UK

COMMISSIONS OF TRUST
2014                              HIV Vaccine Industry Think Tank, Global HIV Vaccine Enterprise, NY, USA
2012-2014                     European and Developing Countries Clinical Trial Partnership (EDCTP)
Stakeholders meetings
2010, 2014                    National Research Foundation / MRC, South Africa
2011 - 2012                   Health and Medical Research Fund, Hong Kong
2008 - 2012                   Infection and Immunity Research Board (IIB), MRC UK
2004,2005,2007-2010     NIH NIAID Special Emphasis Panel
2007                             EMEA European Expert      
2007                             MRC IIB – Translational Vaccine Research call
2006, 2007, 2009           Research Council of Norway
2005-2008                     MRC College of Experts, Infections and Immunity Board
2004, 2005, 2014           South African AIDS Vaccine Initiative
2005                             Site Visit team for the NCI Vaccine Branch, NIH
2003-2004                     Advisory Board, MRC UK
2002-2005                     Ethical Review Panel for the MRC Centre for Macaques
2000                             MRC UK AIDS Vaccine Advisory Subcommittee
2006                             Editorial board, Future HIV Therapy
2003                             Editorial board, Genetic Vaccines and Therapy
2001                             Editorial board, Current Molecular Medicine
2011                             Editorial board, Future Virology

MEMBERSHIPSOFSCIENTIFICSOCIETIES
British Society for Immunology, American Society of Gene & Cell Therapy

MAJOR COLLABORATORS
Dr Lucy Dorrell, Prof Sir Andrew McMichael and Dr Benedikt Kessler, University of Oxford; Wayne Koff, Thomas Hassell, Pat Fast, Christopher Parks et al., The International AIDS Vaccine Initiative; Prof Walter Jaoko, University of Nairobi, Kenya; Dr Bette Korber, Los Alamos National Laboratory, USA; Prof John Moore, Cornell University; Dr Katie Flanagan, formerly MRC Laboratories, The Gambia; Prof Grace John-Stewart, University of Washington, USA; Profs Marie Reilly and Peter Liljeström, Karolinska Institute, Sweden; Prof Sir Mark Pepys, University College London; Prof Christian Brander and Dr Beatriz Mothe, Irsicaixa AIDS Research Institute HIVACAT, Spain; Dr Sarah Fidler, Imperial College London and Dr Joan Joseph, Hospital Clinic Barcelona, Spain; Drs Jerald Sadoff and John Fulkerson, Aeras Global TB Vaccine Foundation, USA; Prof Masafumi Takiguchi University of Kumamoto, Japan; Prof David Watkins, University of Wisconsin; Dr Rocky Cranenburgh, Cobra Biomanufacturing, recently RecipharmCobra Biologics,UK; Profs Mary Jane Potash, David Volsky, University of Columbia; USA, Prof Cornelis Melief, Leiden University Medical Centre, The Netherlands and others.

 

Tomas Hanke

Professor

 

  • E-mail:tomas.hanke@ndm.ox.ac.uk

  • DEPARTMENTDepartment of Medicine
    University of Oxford
  • COUNTRYUK