Publications

  1. Thangavel Samikkannu, Venkata S.R. Atluri, Adriana Y. Arias, Kurapati V. K. Rao, Carmen Mulet,  Madhavan P.N. Nair. HIV-1 Subtypes B and C Tat Differentially Impact Synaptic Plasticity Expression and Implicates HIV-Associated Neurocognitive Disorder.  Current HIV Research 2014; 1: 397-405.
  2. Thangavel Samikkannu, Kurapati V. K. Rao,  Marisela Agudelo,  Andrea Raymond, Hong Ding, Changwon Yoo, Madhavan P.N. Nair. Immunopathogenesis of HIV Infection in Cocaine Users: Role of Arachidonic Acid.  PLOS one 2014; 9(8):e106348.
  3. Kurapati V. K. Rao, Thangavel Samikkannu, Venkata S.R. Atluri, Madhavan P.N. Nair. β- Amyloid 1-42, HIV-1Ba-L (clade B) Infection and Drugs of Abuse Induced Degeneration in Human Neuronal Cells and Protective Effects of Ashwagandha (Withania somnifera). PloS One 2014 9(11):e112818.
  4. Venkata Subba Rao Atluri, Kesava Rao Venkata Kurapati, Thangavel Samikkannu, Madhavan P.N. Nair. Biomarkers of HIV associated Neurocognitive Disorders. JSM Biomarker 2014; 1(1): 1001.
  5. Rao KVK, Atluri VS, Samikkannu T, Nair MP. Cell Cycle Checkpoints and Pathogenesis of HIV-1 infection: A Brief Overview". J Basic Clin Physiol Pharmacol 2014 (In Press).
  6. Atluri VS, Pilakka-Kanthikeel S, Samikkannu T, Sagar V, Kurapati KR, Saxena SK, Yndart A, Raymond A, Ding H, Hernandez O, Nair MP. Vorinostat positively regulates synaptic plasticity genes expression and spine density in HIV infected neurons: role of nicotine in progression of HIV-associated neurocognitive disorder. Mol Brain. 2014; 7(1):37.
  7. Venkata Subba Rao Atluri, Thangavel Samikkannu, Kurapati Rao Venkata, Madhavan P.N Nair. Commentary of Drugs of Abuse and HIV Infection in South Florida, USA.  Austin J Drug Abuse and Addict - Volume 1 Issue 1 – 2014.
  8. Thangavel Samikkannu, Sudhessh Pilakka Kanthikeel, Venkata Atluri, Marisela Agudelo, Madhavan P.N. Nair.  Immuno-Neuropathogenesis of HIV-1 Clade B and C: Role of Redox Expression and Thiol Modification. Free Rad Med Biol 2014; 69: 136-144.
  9. Ding H, Agudelo M, Kanthikeel SP, Guduru R, Sagar V, Atluri V, Thangavel Samikkannu, Nair MN; Enhanced blood-brain barrier transmigration using a novel Transferrin-conjugated fluorescent magnetoliposome nanoformulation.  Nanotechnology 2014; 25: 055101.
  10. Thangavel Samikkannu, Kurapati V.K Rao, Adriana Arias, AarthiKalaichezian, Vidya Sagar, Changwon Yoo and Madhavan P.N Nair. HIV Infection and Drugs of Abuse: Role of Acute Phase Proteins. Journal of Neuroinflammation 2013; 10: 113.
  11. Kurapati V.K. Rao; AVSR Atluri; Thangavel Samikkannu, Madhavan P.N. Nair. Ashwagandha (Withaniasomnifera) Reverses β-Amyloid1-42 Induced Toxicity in Human Neuronal Cells: Implications in HIV-associated neurocognitive disorders (HAND)". PLOS One 8(10):e77624. 
  12. Agudelo M, Yndart A, Morrison M, Muñoz K, Samikkannu, T and Nair MP, Differential Expression of Cannabinoid Genes in Alcohol Users. Drug and Alcohol Dependence-2013; (In Press).
  13. Kurapati KR, Samikkannu T, Kadiyala DB, Zainulabedin SM, Gandhi N, Sathaye SS, Indap MA, Boukli N, Rodriguez JW, Nair MP. Combinatorial cytotoxic effects of Curcuma longa and Zingiberofficinale on the PC-3M prostate cancer cell line. J Basic Clin Physiol Pharmacol. 2012; 23(4):139-46.
  14. Rao KV, Samikkannu T, Dakshayani KB, Zhang X, Sathaye SS, Indap MA, Nair MP. Chemopreventive potential of an ethyl acetate fraction from Curcuma longa is associated with upregulation of p57 (kip2) and Rad9 in the PC-3M prostate cancer cell line. .Asian Pac J Cancer Prev. 2012; 13(3):1031-8.
  15. Nair MP, Samikkannu T. Differential regulation of neurotoxin in HIV clades: role of cocaine and methamphetamine. Cur HIV Res. 2012, 10(5):429-34. Review.
  16. Reddy PV, Gandhi N, Samikkannu T, Saiyed Z, Agudelo M, Yndart A, Khatavkar P, Nair MP. HIV-1 gp120 induces antioxidant response element-mediated expression in primary astrocytes: role in HIV associated neurocognitive disorder. Neurochem Int. 2012, 61(5):807-14.
  17. Samikkannu T, Agudelo.M,Saiyed M, Reddy VB,Nwankwo D, Nair MP. Human immunodeficiency virus type 1 clade B and C gp120 differentially induce neurotoxin arachidonic acid in human astrocytes: Implications for neuro-AIDS. J Neurovirol. 2011, 17, 230-238.
  18. Zainulabedin M. Saiyed, Nimisha Gandhi, Marisela Agudelo, Jessica Napuri1, Thangavel Samikkannu1, Pichili VB Reddy, PradnyaKhatavkar, Adriana Yndart, Shailendra K. Saxena, Madhavan P.N. Nair.  HIV-1 Tat Upregulates Expression of Histone Deacetylase-2 (HDAC2) in Human Neurons: Implication for HIV-Associated Neurocognitive Disorder (HAND). Neurochem Int: 2011, 58, 656-664.
  19. Marisela Agudelo, Nimisha Gandhi, Zainulabedin M. Saiyed, Pichili VB Reddy, Thangavel Samikkannu1, PradnyaKhatavkar, Adriana Yndart, Madhavan P.N. Nair.  Alcohol Upregulates Expression of Histone Deacetylase-2 (HDAC2) in Human Neurons. Alcohol Clin Expe Res, 2011, 35, 1-7.
  20. Kurapati V.K. Rao, Nawal  M. Boukli, Thangavel  Samikkannu, Luis A. Cubano, Babu K. Dakshayani and Madhavan P.N. Nair. Proteomics profiling and cytotoxic effect of curcuma longa on prostate cancer cell. The Open Proteomics Journal, 2011, 14, 1-11.
  21. Thangavel Samikkannu, KurapatiV.K.Rao,Nimisha Gandhi, Madhavan P.N. Nair. HIV-1 Clade B and C Tat differentially Induces Indoleamine-2, 3-Dioxygenase (IDO) and Serotonin in Immature Dendritic Cells (IDC): Implications for Neuro-AIDS. J Neurovirol, 2010, 16, 255-263.
  22. Gandhi N, Saiyed ZM, Napuri J, Samikkannu T, Reddy PV, Agudelo M, Khatavkar P, Saxena SK, Nair MP. Interactive role of human immunodeficiency virus type 1 (HIV-1) clade-specific Tat protein and cocaine in blood-brain barrier dysfunction: Implications for HIV-1-associated neurocognitive disorder. J Neurovirol, 2010, 16, 294-305.
  23. T. Samikkannu, ZM Saiyed, K.V.K.Rao, KB Dakshayani, JW Rodriguez, MN Papuashvili, MP Nair. Differential Regulation of Indoleamine-2, 3-Dioxygenase (IDO) by HIV-1 Clade B and C Tat Proteins. AIDS Res Hum Retroviruses, 2009, 25; 329-335.
  24. Nimisha Gandhi, ZainulabedinSaiyed, Samikkannu Thangavel, Jose Rodriguez, K.V.K. Rao, Madhavan P.N. Nair. Differential effects of HIV-1 clade B and clade C Tat protein on expression of proand anti-inflammatory cytokines by primary monocytes. AIDS Res Hum Retroviruses. 2009, 25; 691-699.
  25. DakshayaniKadiyalaBabu, Alain Diaz, Thangavel Samikkannu, KurapatiV.K.Rao, Zainulabedin M. Saiyed, Jose W. Rodriguez,and Madhavan P.N. Nair.Upregulation of Serotonin Transporter by Alcohol in Human Dendritic Cells: Possible Implication in Neuroimmune Deregulation. Alcohol Clin Exp Res. 2009, 33; 1-8.
  26. Samikkannu.T, Thomas JJ, Bhat GJ, Thekkumkara TJ (2006). Acute effect of High glucose on long-term cell growth: A Role for transient glucose increase in Proximal Tubule cell injury. Am J Physiol Renal Physiol. 2006; 291(1):F162-75.
  27. Bhat GJ, Samikkannu.T, Thomas JJ, Thekkumkara TJ (2004). Alpha thrombin rapidly induces tyrosine phosphorylation of a novel, 74-78 kDa stress response protein(s) in lung fibroblast cells.  J. Biol Chem. 279, 48915-48922.
  28. Yih LH, Gurr JR, Samikkannu T, Bau DT, Lin SY, and Jan KY (2003). Nitric oxide production by Arsenite -- A Review. Mutat Res, 533,173-182.
  29. Samikkannu T, Chen CH, Yih LH, Wang AS, Lin SY, Chen TC, Jan KY. (2003) Reactive oxygen species are involved in arsenic trioxide inhibition of pyruvate dehydrogenase activity. Chem Res Toxicol, 16, 409-14.
  30. Wang TS, Chung CH, Wang AS, Bau DT, Samikkannu T, Jan KY, Cheng YM, Lee TC (2002). Endonuclease III, formamidopyrimidine-DNA glycosylase, and proteinase K additively enhance arsenic-induced DNA strand breaks in human cells. Chem Res Toxicol, 5, 1254-8.
  31. Samikkannu, T. and S. NiranjaliDevaraj (1997). Effect of Methacrylonitrile on rat lung antioxidant enzymes, Bull. Environ. Contam. Toxicol, 59, 894-900.
  32. Samikkannu, T. V. Vasanthakumari and S. NiranjaliDevaraj (1997). Hematological and Erythrocyte membrane changes induced by Methacrylonitrile. Toxicol.Lett, 92, 15-20.
  33. Samikkannu, T. and S. NiranjaliDevaraj (1997). Effect of Methacrylonitrile on Rat lung mitochondria and microsomes. Med. Sci. Res., 25, 129-132.
  34. Samikkannu, T. and S. NiranjaliDevaraj (1997). Toxic effect of Methacrylonitrile on Rat lung. J. Clin.Biochem. Nutr, 23, 27-31.
  35. R.Tamizhselvi, T. Samikkannu and S. Niranjali (1995). Pulmonary Phospholipid changes induced by Butylatedhydroxytoluene an antioxidant, in Rats, Indian J. Exp. Biol., 33, 796 - 797.
  36. Samikkannu, T. and S.V.S. Amanulla Hammed (1994). A study on the accumulation of Copper and Zinc in Meretrixcasta of Agniar Estuary, Indian J. Environ. Protection. 14, 288 - 291.

Samikkannu Thangavel

Assistant Professor

 

  • : 305-348-4978
  • : 305-348-7440
  • DEPARTMENTDepartment of Immunology
    Florida International University
  • COUNTRYUSA