Publications

Refereed Publications(* Denotes Student Contribution)

Refereed Articles

  1. Jeffery, D., Naoko, K., You, Z., Gharib, M., Wyse, B., , Erin Drury, Michael Weireich, Pierre Thibault, Alain Verreault, HisaoMasai, Krassimir Yankulov (2015). CDC28 regulates the association of Chromatin Assembly Factor I with chromatin. C ell Cycle, 14 (01), 74 - 85.
  2. Jeffery, D., Yankulov, K., Crerar, A., & Ritchie, K. (2014). How to achieve accurate peer assessment for high value written assignments in a senior undergraduate course. Assessment and Evaluation in Higher Education.
  3. Yankulov, K. (2013). Dynamics and stability: epigenetic conversions in position effect variegation. Biochemistry and Cell Biology, 91, 6-13.
  4. Jeffery*, D., Wyse*, B., Muhammad*, R., Brown*, G., You, Z., Oshidari* R, Masai H, Yankulov KY (2013). Analysis of epigenetic stability and conversions in Saccharomyces cerevisiae reveals a novel role of CAF-I in position-effect variegation Nucleic Acids Research, 41 (18), 8475-88.
  5. Wyse*, B., Oshidary*, R., Jeffery*, D., & Yankulov, K. (2013). Parasite epigenetics and immune evasion: lessons from budding yeast. Epigenetics & Chromatin, 19 (1), 1.
  6. Yankulov, K. &Couto, R. (2012). Peer review in class: metrics and variations in a senior course Biochem. Biochemistry and Molecular Biology Education, 40, 161-168.
  7. Chisamore-Robert*, P., Peeters*, S., Shostak*, K., & Yankulov, K. (2012). Directional telomeric silencing and lack of canonical B1 elements in two silencer Autonomously Replicating Sequences in S. cerevisiae. BMC Molecular Biology, 113, 34.
  8. Yankulov, K. (2011). Dare to challenge the silence? Telomeric gene silencing revisited. The Nucleus, 2, 513-516.
  9. Power, P., Jeffery, D., Rehman, M. A., Chatterji, A., & Yankulov, K. (2011). Sub-telomeric core X and Y' elements in S. cerevisiae suppress extreme variations in gene silencing. PLoS ONE.
  10. Yankulov, K. (2010). A Zn-finger in Dbf4 is pointing to genotoxic hypersensitivity. Cell Cycle, 9 (10), 1875-6.
  11. Espinosa, M. C., Rehman, M. A., Chisamore-Robert, P., Jeffery, D., & Yankulov, K. (2010). GCN5 is a positive regulator of origins of DNA replication in Saccharomyces cerevisiae. PLoS ONE.
  12. Mathews, A., Holland, L., & Yankulov, K. (2009). The interaction between EAP30 and ELL is modulated by MCM2. F EBS Letters, 583, 3431-6.
  13. Rehman, M. A. & Yankulov, K. (2009). The dual role of autonomously replicating sequences as origins of replication and as silencers. Current Genetics, 55, 357-63.
  14. Rehman, M. A., Wang, D., Fourel, G., Gilson, E., & Yankulov, K. (2009). Subtelomeric ACS-containing proto-silencers act as antisilencers in replication factors mutants in Saccharomyces cerevisiae. Molecular Biology of the Cell, 20, 631-41.
  15. Berthiau, A. S., Yankulov, K., Bah, A., Revardel, E., Luciano, P., Wellinger RJ, Geli V, Gilson E. (2006). Subtelomeric proteins negatively regulate telomere elongation in budding yeast. EMBO Journal, 25, 846-56.
  16. Rehman, M. A., Fourel, G., Mathews, A., Ramdin, D., Espinosa, M., Gilson E, Yankulov K. (2006). Differential requirement of DNA replication factors for subtelomeric ARS consensus sequence protosilencers in Saccharomyces cerevisiae .G enetics, 174, 1801-10.
  17. Pinhero, R., Liaw, P., & Yankulov, K. (2004). A uniform procedure for the purification of CDK7/CycH/MAT1, CDK8/CycC and CDK9/CycT1.Biological Procedures Online, 6, 163-72.
  18. Pinhero, R., Liaw, P., Bertens, K., & Yankulov, K. (2004). Three cyclin-dependent kinases preferentially phosphorylate different parts of the C-terminal domain of the large subunit of RNA polymerase II. The FEBS Journal, 271, 1004-14.
  19. Holland, L. & Yankulov, K. (2003). Two forms of RNA polymerase II holoenzyme display different abundance during the cell cycle. Biochemical and Biophysical Research Communications, 302, 484-8.
  20. Dziak, R., Leishman, D., Radovic, M., Tye, B. K., & Yankulov, K. (2003). Evidence for a role of MCM (mini-chromosome maintenance)5 in transcriptional repression of sub-telomeric and Ty-proximal genes in Saccharomyces cerevisiae .J ournal of Biological Chemistry, 278, 27372-81.
  21. Kramer, D. J., Gauthier, L., & Yankulov, K. (2002). Higher-accuracy method for measuring minichromosome stability in S. cerevisiae. BioTechniques, 32, 1036-40.
  22. Holland, L., Gauthier, L., Bell-Rogers, P., & Yankulov, K. (2002). Distinct parts of minichromosome maintenance protein 2 associate with histone H3/H4 and RNA polymerase II holoenzyme. The FEBS Journal, 269, 5192-202.
  23. Gauthier, L., Dziak, R., Kramer, D. J., Leishman, D., Song, X., Ho J, Radovic M, Bentley D, Yankulov K. (2002). The role of the carboxyterminal domain of RNA polymerase II in regulating origins of DNA replication in Saccharomyces cerevisiae .G enetics, 162, 1117-29.
  24. Yankulov, K., Todorov, I., Romanowski, P., Licatalosi, D., Cilli, K., McCracken S, Laskey R, Bentley DL.= (1999). MCM proteins are associated with RNA polymerase II holoenzyme. Molecular and Cellular Biology, 19, 6154-63.
  25. Yankulov, K. & Bentley, D. (1998). Transcriptional control: Tat cofactors and transcriptional elongation. Current Biology, 8 (13), 447-9.
  26. McCracken, S., Fong, N., Yankulov, K., Ballantyne, S., Pan, G., Greenblatt J, Patterson SD, Wickens M, Bentley DL. (1997). The C-terminal domain of RNA polymerase II couples mRNA processing to transcription. Nature, 385, 357-61.
  27. Yankulov, K. & Bentley, D. L. (1997). Regulation of CDK7 substrate specificity by MAT1 and TFIIH.EMBO Journal, 16, 1638-46.
  28. McCracken, S., Fong, N., Rosonina, E., Yankulov, K., Brothers, G., Siderovski D, Hessel A, Foster S, Shuman S, Bentley DL. (1997). 5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II. G enes& Development, 11, 3306-18.
  29. Yankulov, K., Pandes, M., McCracken, S., Bouchard, D., & Bentley, D. L. (1996). TFIIH functions in regulating transcriptional elongation by RNA polymerase II in Xenopus oocytes. Molecular and Cellular Biology, 16, 3291-9.
  30. Yankulov, K., Yamashita, K., Roy, R., Egly, J. M., & Bentley, D. L. (1995). The transcriptional elongation inhibitor 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole inhibits transcription factor IIH-associated protein kinase. Journal of Biological Chemistry, 270, 23922-5.
  31. Yankulov, K., Blau, J., Purton, T., Roberts, S., & Bentley, D. L. (1994). Transcriptional elongation by RNA polymerase II is stimulated by transactivators. CELL, 77, 749-59.
  32. Hadjiolova, K. V., Martinova, Y. S., Yankulov, K., Davidov, V., Kancheva, L. S., Hadjiolov AA. (1989). An immunocytochemical study of the proliferating cell nuclear matrix antigen p125/6.5 during rat spermatogenesis. Journal of Cell Science, 93, 173-7.
  33. Yankulov, K., Hadjiolova, K. V., Kournev, K. V., Getov, C., &Hadjiolov, A. A. (1989). The use of a monoclonal antibody against a proliferating cell nuclear matrix antigen in the study of solid human tumors. International Journal of Cancer, 43, 800-4.

Presentations of Refereed Papers

International

  1. Yankulov, K. (2012). Regulation of positional variegation at the telomeres: links to DNA replication. Epigenetics and Genomic Stability Conference (CSBCB), Whistler, Canada-British Columbia.
  2. Chisamore-Robert, P., Jeffery, D., & Yankulov, K. (2011). Telomeric gene silencing by Autonomously Replicating Sequences (ARS) in S. cerevisiae: role of B1 elements.Keystone symposium on DNA Replication, Unknown, Unknown.
  3. Paulsen, T., Jeffery, D., Rehman, M., You, Z., Masai, H., Krassimir Yankulov (2010). Is Cdc7p/Dbf4p the major kinase for Chromatin Assembly Factor (CAF-I). 12th Symposium on DNA Replication and Repair, Buffalo, New York.
  4. Robert-Chisamore, P. & Yankulov, K. (2010). Functional differences between silencer and replicator ARS of Saccharomyces cerevisiae through analysis of the B1 element.12th Symposium on DNA Replication and Repair, Buffalo, New York.
  5. Mathews, A. & Yankulov, K. (2009). Interaction between EAP30, ELL and MCM2.FEBS Conference, Prague, Czech Republic.
  6. Yankulov, K. (2009). Positional variegation at yeast telomeres.University of Hokkaido, Sapporo, Japan.
  7. Yankulov, K. (2009). Positional variegation at yeast telomeres.Tokyo Metropolitan Institute of Medicine, Tokyo, Japan.
  8. Rehman, M. A., Espinosa, M., & Yankulov, K. (2008). GCN5 functions as a positive regulator of origins in S. cerevisiae. 11th Symposium on DNA Replication and Repair, Buffalo, New York.
  9. Mathews, A. & Yankulov, K. (2007). Novel Interacting partners of MCM2.10th Symposium on DNA Replication and Repair, Buffalo, New York.
  10. Rehman, M. A., Kita, E., Wang, D., & Yankulov, K. (2007). Telomeric ACSand the regulation of silencing in S.cerevisiae. 10th Symposium on DNA Replication and Repair, Buffalo, New York.
  11. Yankulov, K. (2007). ACS and DNA replication trans-factors as regulators of gene silencing in S.cerevisiae. 10th Symposium on DNA Replication and Repair, Buffalo, New York.
  12. Rehman, M. A. & Yankulov, K. (2006). Differential requirements for replication factors for subtelomeric ACS proto-silencers in S.cerevisiae. 10th Symposium on DNA replication and repair, Buffalo, New York.
  13. Rehman, M. A. & Yankulov, K. (2006). Differential requirements for replication factors for subtelomeric ACS proto-silencers in S.cerevisiae. Differential requirements for replication factors for subtelomeric ACS proto-silencers in S.cerevisiae, Buffalo, New York.
  14. Rehman, M. A., Wang, D., & Yankulov, K. (2005). Effects of MCM5 in the repression pattern of sub-telomeric genes in S.cerevisiae. 48th Annual Conference of the Genetics Society of Canada (GSC), Banff, Canada-Alberta.
  15. Wang, D., Rehman, M. A., & Yankulov, K. (2005). The role of MCM proteins and other DNA replication factors in the regulation of repression at telomeres in S. cerevisiae. 9th Symposium on DNA Replication and Repair, Buffalo, New York.
  16. Wang, D., Rehman, M. A., & Yankulov, K. (2005). The role of MCM proteins and other DNA replication factors in the regulation of repression at telomeres in S. cerevisiae. 9th Symposium on DNA Replication and Repair, Buffalo, New York.
  17. Yankulov, K., Rehman, M., & Wang, D. (2005). Analysis of the mechanism of repression of subtelomeric genes in mcm5 mutants in S. cerevisiae. Telomerase and Telomere Function Conference, Ladenburg, Germany.
  18. Yankulov, K. (2004). Regulation of gene expression at the telomeres of S.cerevisiae.EcoleNormale Superiure, Lyon, France.
  19. Yankulov, K., Dziak, R., Leishman, D., Radovic, M., Bertens, K., Rhalena Thomas (2003). A role of MCM5 in Chromatin Remodeling at Origins of Replication and in Repression of Sub-telomeric and Ty-proximal genes in S. cerevisiae .Chromatin Structure and Function Meeting, Philadelphia, Pennsylvania.
  20. Yankulov, K. (2003). Regulation of DNA replication and of sub-telomeric gene expression in S. cerevisiae. National Institutes of Health, Bethesda, Maryland.
  21. Holland, L., Downey, M., & Yankulov, K. (2002). Distinct Parts of MCM2 Associate with HistoneH3/H4 and RNA polymerase II Holoenzyme.EMBL Meeting on Transcription, Heidelberg, Germany.
  22. Yankulov, K., Gauthier, L., Dziak, R., &Radovic, M. (2002). A role of the carboxyterminal domain of RNA polymerase II in regulating origins of DNA replication in S. cerevisiae. ELSO meeting, Nice, France.
  23. Gauthier, L., Kramer, D., Song, X., Radovic, M., Ho, J., David Bentley, Robert Scalfani, Krassimir Yankulov (2001).G enetic Interaction between MCM5 and the carboxyterminal domain of RNApol II in S. cerevisiae. Eukaryotic DNA Replication, Cold Spring Harbor, New York.
  24. Holland, L., Song, X., Downey, M., Gauthier, L., & Yankulov, K. (2001). The interaction of RNApol II holoenzyme with MCM proteins is mediated b y the N-terminus of MCM2. Mechanisms of Eukaryotic Transcription, Cold Spring Harbor, New York.

National

  1. Chisamore-Robert, P. & Yankulov, K. (2011). Gene silencing by Autonomously Replicating Sequences (ARS) in S. cerevisiae: role of B1 elements. First Canadian Epigenetics Conference. Epigenetic Eh!, London, Canada-Ontario.
  2. Yankulov, K. &Rehman, M. A. (2008). Sub-telomeric ACS-containing proto-silencers act as anti-silencers in replication factors mutants in S.cerevisiae. Yeast Genetics and Molecular Biology Meeting, Toronto, Canada-Ontario.
  3. Yankulov, K. (2006). At origins and ends - MCM proteins, SAGA and the regulation of DNA replication and of sub-telomeric gene expression in S. cerevisiae. University of Waterloo, Waterloo, Canada-Ontario.
  4. Rehman, M. A., Wang, D., & Yankulov, K. (2005). Effects of MCM5 in the repression pattern of sub-telomeric genes in S.cerevisiae. 48th Annual Conference of the Genetics Society of Canada (GSC), Banff, Canada-Alberta.
  5. Pinhero, R., Liaw, P., Bertens, K., & Yankulov, K. (2003). Phosphorylation pattern of RNA polymerase II carboxyl terminal domain by three cyclin-dependent kinases. HUPO 2nd Annual and IUBMB Congress, Montreal, Canada-Quebec.
  6. Yankulov, K. (2003). MCM proteins – potential role in the regulation of gene expression.University of Toronto, Toronto, Canada Ontario.

Invited Chapters

  1. Chisamore-Robert, P., Jeffery, D., & Yankulov, K. (2011). The silencing face of DNA replication: gene repression mediated by DNA replication factors. DNA Replication - Current Advances.InTech Publishing.
  2. Pinhero, R. & Yankulov, K. (2013). Expression and purification of recombinant Cyclin Dependent Kinases: CDK7, CDK8 and CDK9.In M. Orzáez and E. Payá (Eds.), Cyclin-Dependent Kinases. This invited chapter has been accepted by the editors in 2013. Publication is pending

Non-Refereed Articles

 

  1. Yankulov, K. (2014). More than Spelling and Grammar: Students Who Prefer to Write Outperform Students Who Prefer to Present. American Journal of Educational Research.2 (11).
  2. Yankulov, K., Kounev, K. V., &Getov, C. (1989). Monoclonal antibody against a proliferating cell nuclear matrix antigen as a fast marker of tumor boundary in solid tumors of the larynx. O tolaryngologiaPolska, 3, 15-18.

Presentations of Non-Refereed Papers

International

  1. Oshidary, R., Wyse, B., Rowlands, H., & Yankulov, K. (2014). Epigenetic inheritance in S.cerevisiae: interaction between PCNA, CAF-I and RRM3. The 2nd Canadian Conference on Epigenetics: Epigenetics, Eh!, London, Canada-Ontario.

National

  1. Yankulov, K. (2013). Telomere position effect: the ins and outs of epigenetic maintenance. External Seminar Series, Dept. of Biology, York University, Toronto, Canada-Ontario.
  2. Yankulov, K. (2013). Telomere position effect in P. falciparum and S.cerevisiae: a terminal connection? Toronto Hospital Network, Toronto, Canada-Ontario.

Posters And/Or Papers Presented At Conferences

  1. Jeffery, D. & Yankulov, K. (2014). The role of CAF-I in epigenetic conversions and its control by kinases.The 2nd Canadian Conference on Epigenetics: Epigenetics, Eh!, London, Canada-Ontario.
  2. Jeffery, D., You, Z., Masai, H., Verreault, A., & Yankulov, K. (2013). The role of Cac1p in epigenetic conversions of sub-telomeres in S.cerevisiae. Cold Spring Harbor Laboratory Symposium on Chromatin and Epigenetics, Cold Spring Harbor, United States of America.
  3. Jeffery, D., Yankulov, K., Crerar, A., & Ritchie, K. (2013). How to achieve accurate peer evaluation for high value written assignments in a senior undergraduate course. Symposium on Scholarship of Teaching and Learning, Banff, Canada-Alberta.
  4. Jeffery, D., You, Z., Masai, H., & Yankulov, K. (2012). Telomere position effect and the passing/pausing of replication forks.Epigenetics and Genomic Stability, Whistler, Canada-British Columbia.
  5. Jeffery, D. & Yankulov, K. (2012). Peer review in a senior course. 25th Annual Teaching and Learning Innovations Conference, Guelph, Canada-Ontario.

 

Krassimir Joseph Yankulov

Professor

 

  • :SSC 3245
  • DEPARTMENTDepartment of Molecular and Cellular Biology
    University of Guelph
  • COUNTRY Canada