Publications

Selected Peer-reviewed Publications (Selected from 58 peer-reviewed publications)

Most relevant to the current application

1. Miller, E.J.*, Li, J.*, Leng, L., McDonald, C., Atsumi, T., Bucala, R. & Young, L.H. (*equal contribution). (2008). Macrophage migration inhibitory factor stimulates AMP-activated protein kinase. Nature451:578-582. PMID: 18235500
2. Wang, J., Ma, H., Tong, C., Zhang, H., Lawlis, G.B., Li, Y., Zang, M., Ren, J., Nijland, J.M., Ford, S.P., Nathanielsz, P.W. & Li, J. (2010). Overnutrition and maternal obesity in sheep pregnancy alter the JNK­IRS-1 signaling cascades and cardiac function in the fetal heart. FASEB J.24:2066-2076. PMID: 20110268
3. Ma, H., Wang, J., Thomas, D.P., Tong, C., Leng, L., Wang, W.K., Merk, M., Zierow, S., Bernhagen, J., Ren, J., Bucala, R. & Li, J. (2010). Impaired macrophage migration inhibitory factor (MIF)-AMPK activation and ischemic recovery in the senescent heart. Circulation122:282-292. PMCID: PMC2907453 (This paper has been selected by Circulation Editors’ Pick: Most Read Articles in Molecular Cardiology, Circulation,124:e927, 2011)
4. Wang, J., Tong, C., Yan, X., Yeung, E., Gandavadi, S., Hare, A.A., Du, X., Chen, Y., Xiong, H., Ma, C., Leng, L., Young L.H., Jorgensen, W.L., Li, J*. & Bucala, R*. (Co-corresponding authors) (2013). Limiting cardiac ischemic injury by pharmacologic augmentation of MIF-AMPK signal transduction. Circulation128: 225-236. PMID: 23753877
5. Chen, S., Zhu, P., Guo, H.M., Solis, R.S., Wang, Y., Ma, Y., Wang, J., Gao, J., Chen, J.M., Ge, Y., Zhuang, J. & Li J. (2014). Alpha1 catalytic subunit of AMPK modulates contractile function of cardiomyocytes through phosphorylation of troponin I. Life Sci.98:75-82. PM ID: 24447627

Additional recent publications of importance to the field (in chronological order)

1. Li, J., Miller, E.J., Ninomiya-Tsuji, J., Russell, R.R. & Young, L.H. (2005). AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing p38 MAPK recruitment to TAB1 in the ischemic heart. Circ Res.97:872-879. PMID: 16179588
2. Zhang, L., Li, J., Young, L.H. & Caplan, M.J. (2006). AMP-activated protein kinase regulates the assembly of epithelial tight junctions. P Natl Acad Sci USA (PNAS) 103:17272-17277. PMCID: PMC1859922
3. Reznick, R.M., Zong, H., Li, J., Morino, K., Moore, I.K., Yu, H.J., Liu, Z., Dong, J., Mustard, K.J., Hawley, S.A., Befroy, D., Pypaert, M., Hardie, D.G., Young, L.H. & Shulman, GI. (2007). Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis. Cell Metab5:151-156. PMCID: PMC1885964
4. Zhao, P., Wang, J.J., He, L.L., Ma, H., Li, J., Dolence, K., Ren, J. & Li, J. (2009). Deficient in TLR4 signal transduction ameliorates cardiac injury and cardiomyocyte contractile dysfunction during ischemia. J Cell Mol Med13:1513-1525. PMID: 19508385
5. Zhao, P., Wang, J., Xiao, Y., He, L., Tong, C., Wang, Z., Zheng, Q., Dolence, K., Nair, S., Ren, J. & Li, J. (2009). A newly synthetic chromium complex–chrom ium (D-Phenylalanine)3 activates AMP-activated protein kinase and stimulates glucose transport. Biochem Pharm77:1002-1010. PMID: 19073152
6. Wang, J., Yang, L., Rezaie, A.R. & Li, J. (2011). Activated protein C protects against myocardial ischemia/reperfusion injury through AMP-activated protein kinase signaling. J Thromb Haemost9:1308-1317. PMID: 21535395
7. Morrison, A., Yan, X., Tong, C. & Li, J. (2011). Acute rosiglitazone treatment is cardioprotective against ischemia/reperfusion injury by modulating AMPK, Akt, and JNK signaling in non-diabetic mice. Am J Physiol-Heart Cir Physiol301 :H895-H902. PMID: 21666107
8. Li J, Qi D, Cheng H, Hu X, Miller EJ, Wu X, Russell KS, Mikush N, Zhang J, Xiao L, Sherwin RS, Young LH. (2013) Urocortin 2 autocrine/paracrine and pharmacologic effects to activate AMP-activated protein kinase in the heart. Proc Natl Acad Sci USA110:16133-16138. PMID: 24043794
9. Tong, C., Morrison, A., Mattison, S., Qian, S., Bryniarski, M., Rankin, B., Wang, J., Thomas, D.P. & Li J. (2013) Impaired SIRT1 nucleocytoplasmic shutting in the senescent heart during ischemic stress. FASEB J 27:4332-4342. PMID: 23024374
10. Wang, J., Wang, Y., Wang, J., Gao, J., Tong, C., Manithody, C., Li, J*. & Rezaie, A.R*. (*Co-corresponding authors) (2013) Antithrombin is protective against myocardial ischemia and reperfusion injury. J Thromb Haemost13: 1020–1028. PMID: 23582062 (This paper has been selected as Featured Article on www.MDLinx.com in April 2013).