Publications

Peer Reviewed Journals

  1. Ziff OJ, Lawrence AJ, Al-Adra DP, O’Gorman D, Kin T, Shapiro AMJ. Pediatric islet autotransplantation after hereditary pancreatitis with defined genetic variants. CellR4 2014;2:e1197.
  2. Andres A, Kin T, O’Gorman D, Bigam D, Kneteman N, Senior P, Shapiro AMJ. Impact of adverse pancreatic injury at surgical procurement upon islet isolation outcome. Transplant Int 2014 in press.
  3. Balamurugan AN, Naziruddin B, Lockridge A, Tiwari M, Loganathan G, Takita M, Matsumoto S, Papas K, Trieger M, Rainis H, Kin T, Kay TWH, Wease S, Messinger S, Ricordi C, Alejandro R, Markmann J, Kerr-Conti J, Rickels MR, Liu C, Zhang X, Witkowski P, Posselt A, Maffi P, Secchi A, Berney T, O’Connell PJ, Hering BJ, Barton FB. Islet product characteristics and factors related to successful human islet transplantation from the Collaborative Islet Transplant Registry (CITR) 1999-2010. Am J Transplant 2014 in press.
  4. Al-Adra DP, Gill RS, Imes S, O’Gorman D, Kin T, Axford SJ, Shi X, Senior PA, Shapiro AMJ. Single donor islet transplantation and long-term insulin independence in select patients with type 1 diabetes mellitus. Transplantation 2014 in press
  5. Kin T, Abu-Wasel B, AMJ Shapiro. Isolated cystic duct atresia. Dig Liver Dis 2013;46:385-386.
  6. Kin T, AMJ Shapiro. Horseshoe shaped pancreas. JOP. J Pancreas 2014;15:78.
  7. Yamashita S, Ohashi K, Utoh R, Kin T, Shapiro AMJ, Yamamoto M, Gotoh M, Okano T. Quality of air-transported human islets for single islet cells preparations. Cell Medicine 2013;6:33-38.
  8. Priya MM, Mohan V, Ganthimathy S, Anjana RM, Vaz SG, Thiagarajan V, Churchill TA, Kin T, Shapiro AMJ, Lakey JRT. Human islet mass, morphology, and survival after cryopreservation using the Edmonton protocol. Islets 2013;5:188-195.
  9. O’Gorman D, Kin T, Pawlick R, Imes S, Senior P, Shapiro AMJ. Clinical islet isolation outcomes with a highly purified neutral protease for pancreas dissociation. Islets 2013;5:111-115.
  10. Gala-Lopez BL, Semlacher E, Manoucheri N, Kin T, Shapiro AMJ. Autologous islet transplantation after total pancreatectomy for renal cell carcinoma metastases. Am J Transplant 2013, 13:2487-2491.
  11. Kolic J, Spigelman AF, Plummer G, Leung E, Hajmrle C, Kin T, Shapiro AMJ. Manning Fox JE, MacDonald PE. Distinct and opposing roles for p110α and p110β in the regulation of insulin secretion from rodent and human beta cells. Diabetologia 2013;56:1339-1349.
  12. Manning Fox JE, Seeberger K, Dai XQ, Lyon J, Spigelman AF, Kolic J, Hajmrle C, Joseph JW, Kin T, Shapiro AMJ, Korbutt G, MacDonald PE. Functional plasticity of human infant β-cell exocytotic phenotype. Endocrinology 2013;154:1392-1399.
  13. Gala-Lopez B, Kin T, O’Gorman D, Pepper AR, Senior P, Humar A, Shapiro AMJ. Microbial contamination of clinical islet transplant preparations is associated with vey low risk of infection. Diabetes Technol Ther 2013;15:323-327.
  14. Kin T, Korbutt GS, Shapiro AMJ. Possible link between ectopic pancreas and holoprosencephaly. Islets 2012;4:207-209.
  15. Senior P, Kin T, Shapiro AMJ, Koh A. Islet transplantation at the University of Alberta: status update and review of progress over the last decade. Can J Diabetes 2012;36:32-37.
  16. McCall M, Maciver AM, Kin T, Emamaullee J, Pawlick R, Edgar R, Shapiro AMJ. The caspase inhibitor IDN6556 facilitates marginal mass islet engraftment in a porcine islet autotransplant model. Transplantation 2012;94:30-35.
  17. Dai XQ, Manning Fox JE, Chikvashvili D, Casimir M, Plummer G, Hajmrle C, Spigelman AF, Kin T, Singer-Lahat D, Kang Y, Shapiro AMJ, Gaisano HY, Lotan I, MacDonald PE. The Kv2.1 channel regulates insulin secretion from rodent and human islets independent of its electrical function. Diabetologia 2012;55:1709-1720.
  18. McCall M, Pawlick R, Kin T, Shapiro AM. Anakinra potentiates the protective effects of etanercept in transplantation of marginal mass human islets in immunodeficient mice. Am J Transplant 2012;12:322-329.
  19. Westermark GT, Davalli AM, Secchi A, Folli F, Kin T, Toso C, Shapiro AMJ, Korsgren O, Tufveson G, Andersson A, Westermark P. Further evidence for amyloid deposition in clinical pancreatic islet grafts. Transplantation 2012;93:219-223.
  20. Kawahara T, Kin T, Shapiro AMJ. A comparison of islet autotransplantation and allotransplantation and factors elevating acute portal pressure in clinical islet transplantation. J Hepatobiliary Pancreat Sci 2012;19:282-288.
  21. Merani S, McCall MD, Pawlick RL, Edgar RL, Davis J, Toso C, Emamaullee JA, Kin T, Shapiro AMJ. AEB-071 (sotrastaurin) does not exhibit toxic effects on human islets nor transplantation into immunodeficient mice. Islets 2011;3:338-343.
  22. Gala-Lopez BL, Senior PA, Koh A, Kashkoush SM, Kawahara T, Kin T, Humar A, Shapiro AMJ. Late cytomegalovirus transmission and impact of T-depletion in clinical islet transplantation. Am J Transplant 2011;11:2708-2014.
  23. Kawahara T, Kin T, Kashkoush S, Bigam DL, Kneteman NM, Koh A, Senior PA, Shapiro AMJ. Portal vein thrombosis is a preventable complication in clinical islet transplantation. Am J Transplant 2011;11:2700-2707.
  24. McCall M, Toso C, Emamaullee J, Pawlick R, Edgar R, Davis J, Maciver A, Kin T, Arch R, Shapiro AMJ. The caspase inhibitor IDN-6556 (PF3491390) improves marginal mass engraftment after islet transplantation in mice. Surgery 2011;150:48-55.
  25. Kin T, Shapiro AMJ. Surgical aspects of human islet isolation. Islets 2010;2:265-273.
  26. Kin T, O’Gorman D, Senior P, Shapiro AMJ. Experience of islet isolation without neutral protease supplementation. Islets 2010;2:278-282.
  27. O’Gorman D, Kin T, Imes S, Pawlick R, Senior P, Shapiro AMJ. Comparison of human islet isolation outcomes using a new mammalian tissue free enzyme versus Collagenase NB-1. Transplantation 2010;90:255-259.
  28. Kin T, Shapiro AMJ. Partial dorsal agenesis accompanied with circumportal pancreas in a donor for islet transplantation. Islets 2010;2:146-148.
  29. Koh A, Senior P, Salam A, Kin T, Imes S, Dinyari P, Malcolm A, Toso C, Nillson B, Korsgren O, Shapiro AMJ. Insulin-heparin infusion peri-transplant substantially improve single-donor clinical islet transplant success. Transplantation 2010;89:465-471.
  30. Toso C, McCall M, Emamaullee JA, Merani S, Davis J, Edgar R, Pawlick R, Kin T, Knudsen LB, Shapiro AMJ. Liraglutide, a long-acting human glucagon-like peptide 1 analogue, improves human islet survival in culture. Transpl Int 2010;23:259-265.
  31. Koh A, Imes S, Kin T, Dinyari P, Malcolm A, Toso C, Shapiro AMJ, Senior P. Supplemental islet infusions restore insulin independence after graft dysfunction in islet transplant recipients. Transplantation 2010;89:361-365.
  32. Toso C, Isse K, Demetris AJ, Dinyari P, Koh A, Imes S, Kin T, Emamaullee J, Senior P, Shapiro AMJ. Histological graft assessment after clinical islet transplantation. Transplantation 2009;88:1286-1293.
  33. Kin T, O’Gorman D, Zhai X, Pawlick R, Imes S, Senior P, Shapiro AMJ. Nonsimultaneous administration of pancreas dissociation enzymes during islet isolation. Transplantation 2009;87:1700-1705.
  34. Emamaullee JA, Merani S, Toso C, Kin T, Al-Saif F, Truong W, Pawlick R, Davis J, Edgar R, Locke J, Bonner-Weir S, Knudsen LB, Shapiro AMJ. Porcine marginal mass islet autografts resist metabolic failure over time and are enhanced by early treatment with liraglutide. Endocrinology 2009;150:2145-2152.
  35. Kin T, Shapiro AMJ. Circumportal pancreas and islet isolation. Surgery 2009;146:126-127.
  36. Kin T, Zhai X, O’Gorman D, Shapiro AMJ. Detrimental effect of excessive collagenase class II on human islet isolation outcome. Transpl Int 2008;21:1059-1065.
  37. Koh A, Kin T, Imes S, Shapiro AMJ, Senior P. Islets isolated from donors with elevated HbA1c can be successfully transplanted. Transplantation 2008;86:1622-1624.
  38. Kin T, Senior P, O’Gorman D, Richer B, Salam A, Shapiro AMJ. Risk factors for islet loss during culture prior to transplantation. Transpl Int 2008;21:1029-1035.
  39. Kin T, O’Neil JJ, Pawlick R, Korbutt GS, Shapiro AMJ, Lakey JRT. The use of an approved biodegradable polymer scaffold as a solid support system for improvement of islet engraftment. Artificial Organs 2008;32:990-993.
  40. Dufour JM, Lord SJ, Kin T, Rayat GR, Dixon DE, Bleackley RC, Korbutt GS, Rajotte RV. Comparison of successful and unsuccessful islet /Sertoli cell co transplant grafts in streptozotocin-induced diabetic mice. Cell Transplant 2008;16:1029-1038.
  41. Kin T, Korbutt GS. Delayed functional maturation of neonatal porcine islets in recipients under strict glycemic control. Xenotransplantation 2007;14:333-338.
  42. Kin T, Zhai X, Murdoch TB, Salam A, Shapiro AMJ, Lakey JRT. Enhancing the success of human islet isolation through optimization and characterization of pancreas dissociation enzyme. Am J Transplant 2007;7:1233-1241.
  43. Lakey JRT, Kin T, Warnock GL, Shapiro AMJ, Tsapogas P, Imes S, Korbutt GS, Kneteman NM, Rajotte RV, Ryan EA. Long term graft function after allogeneic islet transplantation. Cell Transplant 2007;16:441-446.
  44. Kin T, Rosichuk S, Shapiro AMJ, Lakey JRT. Detection of microbial contamination during human islet isolation. Cell Transplant 2007;16:9-13.
  45. Kin T, Johnson PRV, Shapiro AMJ, Lakey JRT. Factors influencing the collagenase digestion phase of human islet isolation. Transplantation 2007;83:7-12.
  46. Kin T, Mirbolooki M, Salehi P, O’Gorman D, Tsukada M, Imes S, Ryan E, Shapiro AMJ, Lakey JRT. Islet isolation and transplantation outcomes of pancreas preserved with University of Wisconsin solution versus two-layer method using pre-oxygenated perfluorocarbon. Transplantation 2006;82:1286-1290.
  47. Kobayashi T, Aomatsu Y, Iwata H, Kin T, Kanehiro H, Hisanga M, Ko S, Nagao M, Harb G, Nakajima Y. Survival of microencapsulated islets at 400 days posttransplantation in the omental pouch of NOD mice. Cell Transplant 2006;15:359-365.
  48. Kin T, Murdoch T, Shapiro AMJ, Lakey JRT. Estimation of pancreas weight from donor variables. Cell Transplant 2006;15:181-185.
  49. Swift S, Kin T, Mirbolooki M, Wilson R, Lakey JRT. Comparison of cooling systems during islet purification. Cell Transplant 2006;15:175-180.
  50. Salehi P, Mirbolooki M, Kin T, Tsujimura T, Shapiro AM, Churchill TA, Lakey JR. Ameliorating injury during preservation and isolation of human islets using the two-layer method with perfluorocarbon and UW solution. Cell Transplant 2006;15:187-194.
  51. Alsaif F, Molinari M, Al-Masloom A, Lakey JR, Kin T, Shapiro AM. Pancreatic islet autotransplantation with completion pancreatectomy in the management of uncontrolled pancreatic fistula after whipple resection for ampullary adenocarcinoma. Pancreas 2006;32:430-431.
  52. Villiger P, Ryan EA, Owen R, O’kelly K, Oberholzer J, Saif FA, Kin T, Wang H, Larsen I, Blitz SL, Menon V, Senior P, Bigam DL, Paty B, Kneteman NM, Lakey JR, Shapiro AM. Prevention of bleeding after islet transplantation: lessons learned from a multivariate analysis of 132 cases at a single institution. Am J Transplant 2005;5:2992-2998.
  53. Dufour JM, Rajotte RV, Zimmerman M, Rezania A, Kin T, Dixon DE, Korbutt GS. Development of an ectopic site for islet transplantation, using biodegradable scaffolds. Tissue Eng 2005;11:1323-1331.
  54. O’Gorman D, Kin T, Murdoch T, Richer B, McGhee-Wilson D, Ryan E, Shapiro AMJ, Lakey JRT. The standardization of pancreatic donors for islet isolation. Transplantation 2005;80:801-806.
  55. Kin T, Shapiro AMJ, Ryan EA, Lakey JRT. Islet isolation and transplantation from an annular pancreas: a case report. JOP. J Pancreas 2005;6:274-276.
  56. Kin T, Shapiro AMJ, Lakey JRT. Pancreas divisum: a study of the cadaveric donor pancreas for islet isolation. Pancreas 2005;30:325-327.
  57. Kin T, Korbutt GS, Kobayashi T, Dufour JM, Rajotte RV. Reversal of diabetes in pancreatectomized pigs after transplantation of neonatal porcine islets. Diabetes 2005;54:1032-1039.
  58. Street CN, Lakey JR, Shapiro AM, Imes S, Rajotte RV, Ryan EA, Lyon JG, Kin T, Avila J, Tsujimura T, Korbutt GS. Islet graft assessment in the Edmonton protocol: implications for predicting long-term clinical outcome. Diabetes 2004;53:3107-3114.
  59. Kin T, Rajotte RV, Korbutt G. Reassessment of the vascularization of renal subcapsular islet grafts. Pancreas 2004;29:e59-e63.
  60. Tsujimura T, Kuroda Y, Avila JG, Kin T, Oberholzer J, Shapiro AM, Lakey JR. Influence of pancreas preservation on human islet isolation outcomes: impact of the two-layer method. Transplantation 2004;78:96-100.
  61. Street CN, Lakey JRT, Rajotte RV, Shapiro AMJ, Kieffer TJ, Lyon GL, Kin T, Korbutt GS. Enriched human pancreatic ductal cultures obtained from selective death of acinar cells express pancreatic and duodenal homoeobox gene-1 age-dependently. Rev Diabet Stud 2004;1:66-79.
  62. Tsujimura T, Kuroda Y, Churchill TA, Avila JG, Kin T, Shapiro AMJ, Lakey JRT. Short-term storage of the ischemically damaged human pancreas by the two-layer method prior to islet isolation. Cell Transplant 2004;13:67-73.
  63. Dufour JM, Rajotte RV, Seeberger K, Kin T, Korbutt GS. Long-term survival of neonatal porcine Sertoli cells in non-immunosuppressed rats. Xenotransplantation 2003;10:577-586.
  64. Dufour JM, Rajotte RV, Kin T, Korbutt GS. Immunoprotection of rat islet xenografts by cotransplantation with Sertoli cells and a single injection of antilymphocyte serum. Transplantation 2003;75:1594-1596.
  65. Kin T, Korbutt GS, Rajotte RV. Survival and metabolic function of syngeneic rat islet grafts transplanted in the omental pouch. Am J Transplant 2003;3:281-285.
  66. Kobayashi T, Aomatsu Y, Iwata H, KinT, Kanehiro H, Hisanaga M, Ko S, Nagao M, Nakajima Y. Indefinite islet protection from autoimmune destruction in nonobese diabetic mice by agarose microencapsulation without immunosuppression. Transplantation 2003;75:619-625.
  67. Tsujimura T, Kuroda Y, Kin T, Avila JG, Rajotte RV, Korbutt GS, Ryan EA, Shapiro AMJ, Lakey JRT. Human islet transplantation from pancreas with prolonged cold ischemia using additional preservation by the two-layer (UW solution/perfluorochemical) cold-storage method. Transplantation 2002;12:1687-1691.
  68. Kin T, Rajotte RV, Dufour JM, Korbutt GS. Development of an immunoprivileged site to prolong islet allograft survival. Cell Transplant 2002;11:547-552.
  69. Kin T, Iwata H, Aomatsu Y, Ohyama T, Kanehiro H, Hisanaga M, Nakajima Y. Xenotransplantation of pig islets in diabetic dogs with use of a microcapsule composed of agarose and polystyrene sulfonic acid mixed gel. Pancreas 2002;25:94-100.
  70. Ryan A, Lakey JRT, Rajotte RV, Korbutt GS, Kin T, Imes S, Rabinovitch A, Elliott JF, Bigam D, Kneteman NM, Warnock GL, Larsen I, Shapiro J. Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes 2001;50:710-719.
  71. Lakey JRT, Helms LMH, Kin T, Korbutt GS, Rajotte RV, Shapiro AMJ, Warnock GL. Serine-protease inhibition during islet isolation increases islet yield from human pancreases with prolonged ischemia. Transplantation 2001;72:565-570.
  72. Kin T, Nakajima Y, Rajotte RV, Lu W-T, Lakey JRT. Comparison of donor age in outcome of human islet isolation. Japanese Journal of Transplantation 2001;36:225-230.
  73. Kin T, Nakajima Y, Aomatsu Y, Kanehiro H, Hisanaga M, Ko S, Ohyama T, Nakano H. Humoral human xenoreactivity against isolated pig pancreatic islets. Surg Today 2000;30:821-826.
  74. Kin T, Shimano Y, Shinomiya Y, Nakano H. Double cancers of the lung and esophagus associated with a sarcoid-like reaction in their regional lymph nodes: report of a case. Surg Today 1999;29:260-263.
  75. Yamada T, Hisanaga M, Nakajima Y, Kanehiro H, Aomatsu Y, Ko S, Kin T, Nishio K, Sho M, Nagao M, Harada A, Matsushima K, Nakano H. The serum interleukin 8 level reflects hepatic mitochondrial redox state in hyperthermochemohypoxic isolated liver perfusion with use of a venovenous bypass. Surgery 1999;125:304-314.
  76. Aomatsu Y, Nakajima Y. Kin T, Oyama T, Kanehiro H, Hisanaga M, Ko S, Tatekawa Y, Nagao M, Kobayashi T, Urizono M, Yamada T, Iwata H, Warnock GL, Nakano H. Omental pouch site for microencapsulated islet transplantation. Japanese Journal of Transplantation 1999;34:14-21.
  77. Kin T, Nakajima Y, Kanehiro H, Hisanaga M, Ohyama T, Nishio K, Sho M, Nagao M, Nakano H. Repeat hepatectomy for recurrent colorectal metastases. World J Surg 1998;22:1087-1091.
  78. Kin T, Nakajima Y, Kanehiro H, Hisanaga M, Horikawa M, Aomatsu Y, Ko S, Yagura K, Ohyama T, Nakano H. Comparison of hemodynamic changes in two veno-venous bypass techniques modified at the portal cannulation site. J Hepatobiliary Pancreat Surg 1998;5:93-96.
  79. Kin T, Shimano Y, Shinomiya Y, Nakano H. Pseudomyxioma peritonei of ovarian origin associated with mucinous adenocarcinoma of the appendix: Report of a case. Journal of Japan Surgical Association 1998;59:1323-1327.
  80. Nakajima Y, Horikawa M, Kin T, Ohyama T, Kanehiro H, Hisanaga M, Nishio K, Nagao M, Sho M, Yamada T, Ohashi K, Ko S, Nakano H. Hyperthermo-chemo-hypoxic isolated liver perfusion for hepatic metastases: a possible adjuvant approach. Recent Results Cancer Res 1998;147:28-41.
  81. Ko S, Nakajima Y, Kanehiro H, Aomatsu Y, Yoshimura A, Taki J, Kin T, Yagura K, Ohashi K, Nakano H. Transthoracic transdiaphragmatic approach for hepatectomy of Couinaud's segments VII and VIII. World J Surg 1997;21:86-90.
  82. Kobayashi T, Nakajima Y, Kanehiro H, Aomatsu Y, Yoshimura A, Ueno M, Ko S, Kin T, Ohashi K, Nakano H. A case report of ectopic primary hepatocellular carcinoma originated in the ligamentum teres hepatis. The Japanese journal of gastroenterological surgery 1997;30:1004-1008.
  83. Sakaguchi T, Sugihara S, Kin T, Hama N, Terauchi S, Yamaguchi A, Maruyama H, Nakano H. A case report of malignant phyllodes tumor in a 19-year-old woman. The Journal of the Japanese Practical Surgeon Society 1996;57:57-60.
  84. Ko S, Nakajima Y, Kanehiro H, Hisanaga M, Aomatsu Y, Kin T, Yagura K, Ohyama T, Nishio K, Ohashi K, Sho M, Yamada T, Nakano H. Significant influence of accompanying chronic hepatitis status on recurrence of hepatocellular carcinoma after hepatectomy. Result of multivariate analysis. Ann Surg 1996;224:591-595.
  85. Ko S, Nakajima Y, Kanehiro H, Kin T, Aomatsu Y, Yoshimura A, Taki J, Yagura K, Ohashi K, Nakano H. Influence of associated viral hepatitis status on recurrence of hepatocellular carcinoma after hepatectomy. World J Surg 1996;20:1082-1086.
  86. Kin T, Nakajima Y, Kanehiro H, Aomatsu Y, Yoshimura A, Taki J, Ko S, Yagura K, Oyama T, Ohashi K, Nakano H. Effect of complement activation in human serum on isolated porcine islets. Cell Transplant 1996;5:S45-47.
  87. Ohashi K, Nakajima Y, Konishi Y, Kanehiro H, Hisanaga M, Aomatsu Y, Kin T, Yagura K, Nakano H. Telomere shortening in noncancerous liver tissues from patients with hepatocellular carcinoma. Surgical Therapy 1996;74:508-509.
  88. Aomatsu Y, Nakajima Y, Kanehiro H, Hisanaga M, Taki J, Ko S, Kin T, Yagura K, Oyama T, Ohashi K, Nishio K, Yamada T, Nakano H. Agarose-microencapsulated islet xenotransplantation. The Japanese Journal of Gastroenterological Surgery 1996;29:117-121.
  89. Ohashi K, Nakajima Y, Kanehiro H, Tsutsumi M, Taki J, Aomatsu Y, Yoshimura A, Ko S, Kin T, Yagura K, Konishi Y, Nakano H. Ki-ras mutations and p53 protein expressions in intrahepatic cholangiocarcinomas: relation to gross tumor morphology. Gastroenterology 1995;109:1612-1617.
  90. Ko S, Nakajima Y, Kanehiro H, Horikawa M, Yoshimura A, Taki J, Aomatsu Y, Kin T, Yagura K, Nakano H. The enhanced immunosuppressive efficacy of newly developed liposomal FK506 in canine liver transplantation. Transplantation 1995;59:1384-1388.
  91. Ohashi K, Tsutsumi M, Nakajima Y, Majima T, Kanehiro M, Kin T, Okajima E, Nakano H, Konishi Y. Ki-ras point mutation in biliary tract cancers. Journal of Japanese Research Society for Gastroenterological Carcinogenesis 1995;7:363-365.
  92. Nakajima Y, Horikawa M, Kanehiro H, Aomatsu Y, Kido K, Taki J, Yoshimura A, Ueno M, Ko S, Kin T, Yagura K, Nakano H. Hepatectomy under hyperthermic perfusion of the liver for colorectal metastases. Journal of Japanese College of Surgeons 1995;20:89-93.
  93. Ko S, Nakajima Y, Kanehiro H, Aomatsu Y, Yoshimura A, Taki J, Ueno M, Kin T, Nakano H. Successful management of portal hypertension following artificial arterioportal shunting: report of a case. Surg Today 1995;25:557-559.
  94. Ko S, Nakajima Y, Kanehiro H, Taki J, Aomatsu Y, Yoshimura A, Yagura K, Kin T, Ohashi K, Nakano H. The significance of local immunosuppression in canine liver transplantation. Transplantation 1994;57:1818-1821.
  95. Kin T, Shimano Y, Shinomiya Y, Nouka H, Nakano H, Tsutsumi M, Konishi Y. A case of glucagonoma. The Journal of the Japanese Practical Surgeon Society 1992;53:178-182.
  96. Maruyama H, Kin T, Ito N. Ulcerative colitis in an elderly woman: an autopsy case report. Chu-gai-iyaku 1992;45;350-353.
  97. Kin T, Watanabe A, Segawa M, Nakatani K, Nakano H, Nishimura T, Yoshioka A, Fukui H. A case of gastric cancer in von Willebrand’s disease. The Journal of the Japanese Practical Surgeon Society 1990; 51:1491-1495.

Book Chapters

  1. Pepper AR, Gala-Lopez B, Kin T. Advances in clinical islet isolation. In “The Islets of Langerhans, 2nd edition, Advances in Experimental Medicine and Biology”, Springer Science, Edited by Md. S. Islam,
  2. Kin T. Biodegradable Polymers for Islet Cell Transplantation. In “Biodegradable Polymers: Processing, Degradation and Applications”, Nova Science Publishers, Inc, Edited by Felton GP, 2011
  3. Kin T. Islet isolation for clinical transplantation. In “The Islets of Langerhans, Advances in Experimental Medicine and Biology”, Springer Science, Edited by Md. S. Islam, March 2010.
  4. Lakey JRT, Mirbolooki M, Kin T, Murdoch T, Shapiro AMJ. Aspects and challenges in islet isolation. In “Islet Transplantation and Beta Cell Replacement Therapy”, Informa Healthcare, Edited by Shapiro AMJ and Shaw JAM, July 2007.
  5. Kin T, Mirbolooki M, Lakey JRT. Design and implementation of a cell processing facility. In "Cellular Transplantation: From Laboratory to Clinic", Elsevier Science & Technology, Edited by Craig Halberstatd and Dwaine F. Emerich, Nov 2006.

Invited Articles and Letters

  1. Kin T, AMJ Shapiro. Letter to the Editor (Retroportal main pancreatic duct with circumportal pancreas: radiographic visualization). Clinical Imaging 2012;36:84.
  2. Kin T, Nakajima Y. Current status and future progress of clinical islet transplantation. Frontiers in Gastroenterology 2003;8:283-290.
  3. Kin T, Iwata H, Aomastu Y, Ohyama T, Kanehiro H, Hisanaga M, Nakajima Y. Xenotransplantation of pig islets in diabetic dogs with use of a microcapsule composed of agarose and polystyrene sulfonic acid mixed gel. The Journal of Japan Pancreas Society 2003;18:85-86.
  4. Kin T. Current status of islet transplant. Renal Transplantation Vascular Surgery 2002;14:144-148.
  5. KinT. Pancreas and islet transplantation and organ donation in Japan. Insulin-Free Times 2001;Spring/Summer:30-32.
  6. Kin T, Nakajima Y. Islet transplantation at the University of Alberta. Transplantation Now 2001;14:346-347.
  7. Kin T, Nakajima Y, Nakano H. Reply to letter by Papadimitriou JD, et al. World J Surgery 2000;24:621.
  8. Kin T, Nakajima Y, Kanehiro H, Hisanaga H, Aomatsu Y, Oyama T, Yamada T, Nakano H. In vitro model of hyper acute rejection in pig to human islet cell transplantation. Transplantation Now 1996;11:81-84.
  9. Kin T, Nakajima Y, Kanehiro H, Aomatsu Y, Yoshimura J, Taki J, Ueno M, Ko S, Yagura K, Oyama T, Ohashi K, Nakano H. Pig islet isolation towards pig to human islet transplantation. Transplantation Now 1996;9:53-57.
  10. Nakajima Y, Kin T, Nakano H. Recurrence patterns in patients with pancreatic endocrine tumor. Kan-Tan-Sui 1995;22:1799-1806.

Published Congress Proceedings

  1. Kitzmann JP, O'Gorman D, Kin T, Gruessner AC, Senior P, Imes S, Gruessner RW, Shapiro AMJ, Papas KK. Islet oxygen consumption rate predicts clinical islet allo-transplant insulin independence for first transplants. Transplant Proc 2014;46:1985-1988.
  2. Kitzmann JP, Pepper AR, Lopez BG, Pawlick R, Kin T, O’Gorman D, Mueller KR, Gruessner AC, Avgoustiniatos ES, Karatzas T, Szot GL, Posselt AM, Stock PG, Wilson JR, Shapiro AM, Papas KK. Human islet viability and function is maintained during high density shipment on silicone rubber membrane vessels. Transplant Proc 2014;46:1989-1991.
  3. Kin T, O’Gorman D, Schroeder A, Onderka C, Richer B, Rosichuk S, Zhai X, AM J Shapiro. Human islet distribution program for basic research at a single center. Transplant Proc 2011;43:3195-3197.
  4. O’Gorman D, Kin T, McGhee-Wilson D, Shapiro AM, Lakey JR. Multi-lot analysis of custom collagenase enzyme blend in human islet isolations. Transplant Proc 2005;37:3417-3419.
  5. O’Gorman D, Kin T, Murdoch T, Richer B, McGhee-Wilson D, Ryan E, Shapiro AMJ, Lakey JRT. The standardization of pancreatic donors for islet isolation. Transplant Proc 2005;37:1309-1310.
  6. Tsujimura T, Kuroda Y, Avila JG, Kin T, Churchill TA, Shapiro AMJ, Lakey JRT. Resuscitation of the ischemically damaged human pancreas by the two-layer method prior to islet isolation. Transplant Proc 2003;35:2461-2462.
  7. Aomatsu Y, Nakajima Y, Ohyama T, Kin T, Kanehiro H, Hisanaga M, Ko S, Nagao M, Tatekawa Y, Sho M, Ikeda N, Kanokogi H, Kobayashi T, Urizono Y, Yamada T, Shibaji T, Kanamura T, Ogawa S, Iwata H, Nakano H. Efficacy of agarose/polystyrene sulfonic acid microencapsulation for islet xenotransplantation. Transplant Proc 2000;32:1071-1072.
  8. Kin T, Nakajima Y, Kanehiro H, Hisanaga M, Aomatsu Y, Ohyama T, Nishio K, Sho M, Nagao M, Yamada T, Nakano H. Humoral xenoreactivity in pig-to-human islet cell xenotransplantation. Transplant Proc 1998;30:81-82.
  9. Sho M, Nakajima Y, Hisanaga M, Kanehiro H, Kin T, Ohyama T, Nishio K, Nagao M, Ikeda N, Kanokogi H, Yamada T, Nakano H. Simultaneous inoculation of donor lymphocyte subsets with transplantation in a rat cardiac allograft model. Transplant Proc 1998;30:3876-3878.
  10. Ohyama T, Nakajima Y, Kanehiro H, Hisanaga M, Aomatsu Y, Kin T, Nishio K, Ohashi K, Sho M, Nagao M, Tatekawa Y, Ikeda N, Kanokogi H, Yamada T, Iwata H, Nakano H. Long-term normalization of diabetes by xenotransplantation of newly developed encapsulated pancreatic islets. Transplant Proc 1998;30:3433-3435.
  11. Nishio K, Nakajima Y, Kanehiro H, Hisanaga M, Kin T, Ohyama T, Ohashi K, Sho M, Nagao M, Tatekawa Y, Ikeda N, Kanokogi H, Yamada T, Nakano H. Development of auxiliary partial orthotopic liver transplantation model in the rat. Transplant Proc 1998;30:3237-3238.
  12. Ko S, Nakajima Y, Kanehiro H, Hisanaga M, Horikawa M, Aomatsu Y, Yagura K, Kin T, Ohyama T, Nishio K, Yamada T, Nakano H. Predominant role of local immunosuppressive effect in enhanced efficacy of liposomal FK506 in organ transplantation. Transplant Proc 1997;29:529-531.
  13. Ko S, Nakajima Y, Kanehiro H, Aomatsu Y, Yoshimura A, Taki J, Kin T, Yagura K, Oyama T, Yagi M, Shimomura H, Nakano H. Liver transplantation for hepatocellular carcinoma: consideration from the findings on autopsy. Transplant Proc 1996;28:1691-1692.
  14. Kin T, Nakajima Y, Kanehiro H, Aomatsu Y, Yoshimura A, Taki J, Ko S, Nakano H. Influence of complement in human serum on isolated porcine islets. Transplant Proc 1996;28:836.
  15. Ko S, Nakajima Y, Kanehiro H, Horikawa M, Yoshimura A, Kido K, Taki J, Aomatsu Y, Kin T, Yagura K, Ohyama T, Ohashi K, Yamada T, Nakano H. Different immunosuppressive effects of liposomal FK506 in liver and kidney transplantation. Transplant Proc 1996;28:1066-1068.
  16. Ko S, Nakajima Y, Kanehiro H, Horikawa M, Yoshimura A, Taki J, Kido K, Aomatsu Y, Ueno M, Kin T, Nakano H. Significance of newly developed liposomal FK 506 in canine liver transplantation. Transplant Proc 1995;27:351-353.
  17. Aomatsu Y, Nakajima Y, Iwata H, Amemiya H, Kanehiro H, Hisanaga M, Yoshimura A, Kido K, Taki J, Horikawa M, Ko S, Kin T, Yagura K, Oyama T, Ohashi K, Nakano H. Significance of low-doses of 15-deoxyspergualin in agarose-microencapsulated discordant islet xenotransplantation. Transplant Proc 1995;27:292-293.

 

 

Tatsuya Kin

Director

 

  • : 780-407-8671
  • DEPARTMENTClinical Islet Laboratory
    University of Alberta/Alberta Health Services

  • COUNTRYCanada